Its chemical structure consists of a thieno[3,2-c]pyridine ring, a piperazine ring, and a phenyl group. (thebiotek.com)
Methyl1
Our products include methyl (ethyl/butyl/propyl/benzyl) carbamate, methyl (ethyl) piperazine, trazodone hydrochloride intermediates and fosinopril sodium intermediates. (amcua.com)
Hydrochloride1
Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines;Biochemistry;Reagents for Oligosaccharide Synthesis;Highly Purified Reagents;Other Categories;Zone Refined Products;Buffer;ACS Grade Buffers;ACS Grade;Biological Buffers;Buffers A to Z;Building Blocks;C3 to C8;Chemical Synthesis;Essential Chemicals;Heterocyclic Building Blocks;Imidazoles;Inorganic Salts;Research Essentials;Solutions and Reagents;Intermediate for Propafenone hydrochloride. (lookchem.com)
A recently introduced drug, 2-[4-(2-furoyl)-1-piperazine-1-yl]-4-amino-6,7-dimethoxyquinazoline, commonly identified by the generic name prazosin, is a hypotensive drug producing peripheral arterial dilation. (justia.com)
X-ray structure of Sitagliptin with DPP-IV indicated hydrophobic interaction of the triazolo-piperazine ring system with the S2 pocket through the amino acid Phe357. (ommegaonline.org)
The current research aimed to design molecules maintaining the β-amino amide pharmacophore of Sitagliptin, but with the triazolo-piperazine ring system replaced by more lipophilic entities for better hydrophobic interactions with Phe 357 in the S2 pocket. (ommegaonline.org)
Pyridine4
studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity. (chemenu.com)
Ifenprodil can be synthesized using various methods, including the reaction of 4-bromo-2,3,6,7-tetrahydrothieno[3,2-c]pyridine with 1-(4-methoxyphenyl)piperazine in the presence of a palladium catalyst. (thebiotek.com)
Another method involves the reaction of 4-bromo-2,3,6,7-tetrahydrothieno[3,2-c]pyridine with 1-(4-fluorophenyl)piperazine in the presence of a copper catalyst. (thebiotek.com)
The Co(III) ion is six-coordinated with octahedral geometry, the pyridine rings are planar and the piperazine rings assume chair conformations. (mdpi.com)
Compounds3
Buy low price, high quality bridged compounds and bridged bicyclic compounds,choose our products,Chemenu is the leading factory & company. (chemenu.com)
As such, EFSA is requesting analytical data on levels of degradation products of aspartame in various products on the market in order to characterize the extent of exposure to these compounds. (dicentra.com)
After uptake of H.sub.2 ceased, the catalyst was filtered, the solvent concentrated, and the residue crystallized from isopropyl alcohol to give 35.2 g. tetrahydrofuroyl piperazine HBr, m.p. 152.degree. (justia.com)
ACID2
This compound converted to the acid chloride with oxalyl chloride and is then treated with N-benzyl piperazine. (justia.com)
However, the European Commission has requested that the risk assessment for aspartame be prioritized by EFSA with an earlier evaluation deadline of July 31, 2012 due to concerns over the presence of degradation products, in particular DKP (5-Benzyl-3,6-dioxo-2-piperazine acetic acid). (dicentra.com)
Pharmaceutical3
The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. (chemenu.com)
All products of Huateng pharmaceutical are only used for scientific research, research on registration and application for approval by the drug regulatory authority and the production and manufacturing of drugs licensed by the drug regulatory authority for marketing. (huatengsci.com)
Motivated by return-on-investment, WHO to help Member States to formulate the pharmaceutical industry and private national pharmaceutical policies that meet pharmacies fill the shelves with products the actual health needs of the people [ 6 ]. (who.int)
Organic2
Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. (chemenu.com)
Aftercompletion of the reaction, 10 cm3acetonitrile was addedto the reaction mixture and the mixture heated for 10 minat 50 °C. After that, the catalyst was separated from thereaction mixture by filtration and the organic residue wasextracted with 20 cm3EtOAc, washed with 10 cm3distilledwater, dried over MgSO4,and recrystallized in a mixture ofEtOH and H2Oto obtain the pure product. (ambeed.com)
Biological activity1
References are publications that support the biological activity of the product. (tocris.com)
Chemicals2
Today it produces other kinds of products including electrolytic manganese dioxide (EMD), specialty polymers, fine chemicals, scientific instruments, and thin-film materials. (wikipedia.org)
Determination of skin irritation potential is an international regulatory requirement to ensure safe handling, packaging, labeling and transport of chemicals and evaluation of cosmetics and household products. (mattek.com)
Drug3
Natural Products as Tools for Neuroscience: Discovery and Development of Novel Agents to Treat Drug Abuse. (acs.org)
Our products aim to reduce the organ shortage and speed up drug development by providing accessible life science solutions that combine biology and technology, fundamentally shifting the global healthcare industry. (mattek.com)
X-ray crystal structure of Sitagliptin bound to DPP-IV, (Figure-2), illustrates that the triazolo-piperazine fragment of the drug is oriented towards the Phe357 residue in the catalytic site, and the trifluromethyl group towards the Ser209 residue. (ommegaonline.org)
Services2
Search for products or services , then visit the suppliers website for prices or more information. (americanchemicalsuppliers.com)
Please let us know what you think of our products and services. (mdpi.com)
Storage1
For its full review of aspartame, EFSA is seeking data on degradation products of aspartame that may arise under certain storage conditions of foods and/or beverages. (dicentra.com)
Natural health p2
Aspartame, also known as E 951, is an artificial sweetener that has been approved for use in foods and beverages in the European Union (EU), and as a flavour enhancer or sweetening agent for non-medicinal purposes in natural health products (NHPs) in Canada. (dicentra.com)
Natural health Products Ingredients Database (NHPID), 2012. (dicentra.com)
Important1
Keep in mind that natural products are not always necessarily safe and dosages can be important. (medlineplus.gov)
Tablets2
parts of plants, dried plants, pressed plants, powders, tablets, capsules, extracts, tinctures and any other products of the abovementioned plants that contain the substances included in the Schedule I of Narcotic Substances, Psychotropic Substances and Precursors to be Controlled in Latvia, except products that are allowed for distribution in accordance with the laws and regulations regarding food handling. (likumi.lv)
3. The physical appearance of the tablets, capsules or other finished product containing the substance is substantially identical to a specified controlled substance. (ncleg.net)
Primary3
Listed below are the five groups and their primary products: Petrochemical Group Olefins: ethylene, propylene and polypropylene, tert-Butanol, and aromatics. (wikipedia.org)
Due to limitations in the available data for DKP and other primary and secondary degradation products of aspartame when the evaluation commenced in September 2011, EFSA has requested and was granted an extension for the full re-evaluation until May 2013 by the European Commission 4 . (dicentra.com)
The extension will allow stakeholders and all interested parties to submit not only published data, but any unpublished or newly generated data for DKP and primary and secondary degradation products of aspartame to EFSA. (dicentra.com)
Data1
For interested parties and stake holders, the deadline to submit data to EFSA for aspartame and its degradation products (including DKP) has been extended until September 30, 2012 3 . (dicentra.com)
Quality1
And we always serve customers throughout the world with high quality products and good service. (amcua.com)
Professional2
b) Guide our clients by professional knowledge and teach them how to use our product after sales. (chemicalorigin.com)
Be sure to follow relevant directions on product labels and consult a healthcare professional before using. (medlineplus.gov)
High1
The Specialty Group focuses on products for high-tech industries such as semiconductors, consumer electronics, pharmaceuticals, and healthcare. (wikipedia.org)
Animal1
With respect to the degradation product DKP, extensive animal studies have been examined and summarized by The Joint FAO/WHO Expert Committee on Food Additives (JECFA). (dicentra.com)
Research1
The product is for non-human research only. (thebiotek.com)
Evaluation1
Synthesis, Fluorine-18 Radiolabeling, and Biological Evaluation of N-((E)-4-Fluorobut-2-en-1-yl)-2β-carbomethoxy-3β-(4′-halophenyl)nortropanes: Candidate Radioligands for In Vivo Imaging of the BrainDopamine Transporter with Positron Emission Tomography. (acs.org)