These transformations tolerated a broad range of the nucleophilic reagents thus allowing the synthesis of a wide variety of hetero- and carbocyclic compounds including the derivatives of pyridine, pyrimidine, pyrazole, pyran, dioxane, and isoxazole as well as their heterofused derivatives. (researchgate.net)
The benzene and phenyl rings form dihedral angles of 85.81 (2) and 88.90 (2)°, respectively, with the mean plane of the di-hydro-pyridine ring. (iucr.org)
Phenyl2
This structure is further coupled with a phenyl pyrimidine derivative, making it a compound of significant interest in the field of organic electronics. (noctiluca.eu)
The ring system of benzene is called benzene ring, and the structure after removing one hydrogen atom from the benzene ring is called phenyl. (chemenu.com)
Compounds10
The fusion of two benzene rings gives rise to a third large family of organic compounds. (wikipedia.org)
Analogs of the previously mentioned heterocycles for this third family of compounds are acridine, dibenzothiophene, carbazole, and dibenzofuran, respectively. (wikipedia.org)
Likewise, the compounds with two benzene rings fused to the central heterocycle are carbazole, acridine, and dibenzoazepine. (wikipedia.org)
1990. Significance of exposure to benzene and other toxic compounds through environmental tobacco smoke. (cdc.gov)
Imidazolidine derivatives are key components in the development of bioactive compounds for the treatment of various diseases, especially Chagas disease. (chemenu.com)
Among the numerous heterocyclic compounds, imidazole and its derivatives are regarded as a unique and multifaceted scaffold material due to their diverse applications in industrial, organic and pharmaceutical chemistry. (chemenu.com)
All the derivatives are characterized by TLC and spectral analysis 1H NMR, 13 C NMR, IR, MASS. All the synthesized compounds were screened as in vitro anti-cancer, and anti-bacterial activity. (jyoungpharm.org)
Quinoxalines, also known as benzopyrazines, are heterocyclic compounds containing a ring complex consisting of a benzene ring and a pyrazine ring. (chemenu.com)
Aliphatic hydrocarbons and their derivatives (including halogenated hydrocarbons) and alicyclic hydrocarbons and their derivatives are collectively referred to as aliphatic compounds. (chemenu.com)
Quinuclidine derivatives are used as catalysts, chiral building blocks, and intermediates in the synthesis of pharmaceutical compounds. (chemenu.com)
Pyrimidine3
Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. (chemenu.com)
Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. (chemenu.com)
In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. (chemenu.com)
Intermediates2
Many important chemical intermediates can be derived from benzene through substitution reaction, addition reaction and benzene ring cleavage reaction. (chemenu.com)
Benzoisothiazole is a benzo derivative of isothiazole, which is a kind of bicyclic aromatic organic compound, which is formed by fusion of a six-membered benzene ring and a five-membered heterocyclic ring composed of two adjacent heteroatoms, N and S. Benzoisothiazoles are important pharmaceutical intermediates. (chemenu.com)
Atoms1
Benzene is an important organic compound with the chemical formula C6H6, and its molecule consists of a ring of 6 carbon atoms, each with 1 hydrogen atom. (chemenu.com)
19871
1987. Exposure to benzene in Turkey between 1983 and 1985: A haematological study on 231 workers. (cdc.gov)
Antitumor activities2
Aim: A series of novel trifluoromethylquinoline derivatives were designed, synthesized and evaluated for antitumor activities. (bvsalud.org)
Some benzoisothiazole derivatives exhibit potent cytotoxic and antitumor activities. (chemenu.com)
Inhibition1
5'-O-tritylated nucleoside derivatives: inhibition of thymidine phosphorylase and angiogenesis. (shengsci.com)
Heterocycles2
Another large class of organic heterocycles refers to those fused to benzene rings. (wikipedia.org)
The saturated organic heterocycles behave like the acyclic derivatives. (wikipedia.org)
Aromatic1
Benzene is a sweet, flammable, colorless and transparent liquid with carcinogenic toxicity at room temperature, and has a strong aromatic odor. (chemenu.com)
Anticancer2
In a previous study, the research group discovered a series of chalcone derivatives with stronger anticancer activities. (bvsalud.org)
To find better anticancer drugs, novel chalcone derivatives A1-A14, B1-B14 have continuously been designed and synthesized. (bvsalud.org)
Synthesis3
The Project Gutenberg eBook of Synthesis of 2-methyl-4-selenoquinazolone 2-phenylbenzoselenazole, and Its Derivatives, by Y -Gwan Chen, M. A. (gutenberg.org)
The Project Gutenberg EBook of Synthesis of 2-methyl-4-selenoquinazolone, 2-phenylbenzoselenazole, and its derivatives, by Y -Gwan Chen This eBook is for the use of anyone anywhere in the United States and most other parts of the world at no cost and with almost no restrictions whatsoever. (gutenberg.org)
In this study, we explored the catalyst‐free one‐pot multi‐component synthesis of 1,4‐dihydropyridine derivatives by following green chemistry protocol. (researchgate.net)
Biological5
Some noteworthy developments: 1818: Brugnatelli makes alloxan from uric acid 1832: Dobereiner produces furfural (a furan) by treating starch with sulfuric acid 1834: Runge obtains pyrrole ("fiery oil") by dry distillation of bones 1906: Friedlander synthesizes indigo dye, allowing synthetic chemistry to displace a large agricultural industry 1936: Treibs isolates chlorophyl derivatives from crude oil, explaining the biological origin of petroleum. (wikipedia.org)
1936: Treibs isolates chlorophyl derivatives from crude oil, explaining the biological origin of petroleum. (alchetron.com)
The crystal structures of acridinedione derivatives are expected to provide useful information on the mol-ecular conformation, which has a direct relationship to biological activity. (iucr.org)
In this review we summarize the current state of the art in detailing the three main categories of quadruplex-binding macrocycles described so far (telomestatin-like polyheteroarenes, porphyrins and derivatives, polyammonium cyclophanes), and in addressing both synthetic issues and biological aspects. (hindawi.com)
Biological effects resulting from the Cu/Zn-superoxide dismutase-accelerated oxidation of the benzene metabolite 1,4-hydroquinone. (shengsci.com)
Organic4
The study of organic heterocyclic chemistry focuses especially on organic unsaturated derivatives, and the preponderance of work and applications involves unstrained organic 5- and 6-membered rings. (wikipedia.org)
Among these, DMQA officially known as 5,12-Dihydro-5,12-dimethylquino[2,3-b]acridine-7,14-dione stands as a pivotal component in the technology stack for organic devices, particularly OLEDs and organic photovoltaic (OPV) devices. (noctiluca.eu)
DMQA is an organic compound characterized by its unique molecular structure, which comprises two 9,9-dimethyl-9,10-dihydroacridine units substituted to a benzene ring. (noctiluca.eu)
Benzene is one of the most important basic organic chemical raw materials. (chemenu.com)
Occupational1
Different types of malignancies due to occupational exposure to benzene: A review of recent observations in Turkey. (cdc.gov)
Compound2
These results suggested that compound A14 could be a promising chalcone derivative for further anti-breast cancer research. (bvsalud.org)
An azido derivative of [3H2](2S, 3S)-cis-2-(diphenylmethyl)-N-((2-methoxyphenyl) methyl)-1-azabicyclo[2.2.2]octon-3-amine (CP-96,345), a potent nonpeptide antagonist of the substance P (SP) (neurokinin-1) receptor, was synthesized and shown to have an affinity for the human SP receptor similar to that of the parent compound, CP-96,345. (shengsci.com)
Widely1
There are many kinds of 1,8-naphthyridine derivatives, and they are widely used. (chemenu.com)
Molecular1
The benzimidazole drugs share a common molecular structure, triclabendazole being the exception in having a chlorinated benzene ring but no carbamate group. (curezone.org)
Rings1
There are ten isomers of naphthyridine, because naphthyridine has two benzene rings, has strong π-π conjugation, and has better luminescence properties. (chemenu.com)
Structure1
Acetone has a simple structure (CH3COCH3) and is the smallest ketone, whereas benzaldehyde (C6H5CHO) contains a benzene ring. (askanydifference.com)
Form1
Glucosamine usually exists in microbial, animal derived polysaccharides and bound polysaccharides in the form of N-neneneba acetyl derivatives (such as chitin) or N-nenenebb sulfate and N-acetyl-3-O-lactate ether (cell wall acid). (chemenu.com)
Study1
Followup study on the mortality and the development of leukemia in 44 pancytopenic patients with chronic benzene exposure. (cdc.gov)
Large1
Although the DMAC derivatives show negligible delayed emission because of their large singlet-triplet excited state energy difference, 1EST, PXZ-based molecules, especially PXZ-OBO with an experimental 1EST of 0.25 eV, demonstrate delayed emission in blend mCP films at room temperature, which suggests triplet exciton harvesting occurs in these samples, potentially by thermally activated delayed fluorescence. (itn-tadflife.de)
Blocks1
A new series of thiazolyl-pyrazoline derivatives (4a-d, 5a-d 6a, b, 7a-d, 8a, b, and 10a, b) have been designed and synthesized through the combination of thiazole and pyrazoline moieties, starting from the key building blocks pyrazoline carbothioamides (1a-b). (bvsalud.org)