• death
  • This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. (wikipedia.org)
  • For the death pathway, the caspase-8 zymogen is cleaved into subunits that assemble to form the mature, highly active caspase heterotetramer whereas for the activation pathway, the zymogen appears to remain intact perhaps to limit its proteolytic function but enhance its capability as an adapter protein. (wikipedia.org)
  • activity
  • However, results in the ability of these isoforms to bind to the BAD and BAK proteins, as well as in the structural topology and electrostatic potential of the binding groove, suggest differences in antiapoptotic activity for the two isoforms. (wikipedia.org)
  • Cytochrome c can also catalyze several redox reactions such as hydroxylation and aromatic oxidation , and shows peroxidase activity by oxidation of various electron donors such as 2,2-azino- bis (3-ethylbenzthiazoline-6-sulphonic acid) ( ABTS ), 2-keto-4-thiomethyl butyric acid and 4-aminoantipyrine. (wikipedia.org)
  • produce
  • But simultaneous over-expression of Bcl-2 and the proto-oncogene myc may produce aggressive B-cell malignancies including lymphoma. (wikipedia.org)
  • found
  • Cytochrome c is a highly conserved protein across the spectrum of species, found in plants, animals, and many unicellular organisms. (wikipedia.org)