• High cytoplasmic OPN staining was observed in 100% of gastric carcinomas, 85% of colorectal carcinomas, 82% of transitional cell carcinomas of the renal pelvis, 81% of pancreatic carcinomas, 72% of renal cell carcinomas, 71% of lung and endometrial carcinomas, 70% of esophageal carcinomas, 58% of squamous cell carcinomas of the head and neck, and 59% of ovarian carcinomas. (aacrjournals.org)
  • This cytokeratin cocktail can be useful in differentiation of the squamous cell carcinomas and adenocarcinomas. (celltechgen.com)
  • Methods and Materials: Protein levels of p21(WAF1/CIP1), p53, bax, and bcl-2 were determined in 8 carcinomas (3 mammary carcinomas designated MCa-4, MCa-29, and MCa-35, 2 squamous cell carcinomas designated SCC-IV and SCC-VII, ovarian adenocarcinoma OCa-I, hepatocarcinoma HCa-I, and adenosquamous carcinoma ACa SG) syngeneic to C3Hf/Kam mice using Western blot analysis. (elsevierpure.com)
  • Primary malignant skin neoplasms most often are carcinomas (either basal cell or squamous cell carcinomas) or melanomas. (nih.gov)
  • 90%) are squamous cell carcinomas (SCCs) with an incidence of 1 to 3/100,000 in the United States and Europe per year. (entokey.com)
  • mucinous, villoglandular, endometrioid) Clear cell adenocarcinoma Serous carcinoma Adenosquamous carcinoma Glassy cell carcinoma Adenoid cystic carcinoma Adenoid basal carcinoma Small cell carcinoma Undifferentiated carcinoma Cancers can be histopathologically graded as follows: GX: Grade cannot be assessed G1: Well differentiated G2: Moderately differentiated G3: Poorly or undifferentiated For microinvasive disease, clinicians should collect a specimen using a loop electrosurgical excision procedure (LEEP) or a cone biopsy. (wikipedia.org)
  • Sarcomas and basal cell carcinomas with underlying adenocarcinoma also occur. (msdmanuals.com)
  • Squamous cell carcinoma and adenocarcinoma are the most common variants that arise in the cervix. (medscape.com)
  • Microscopically, early gastric carcinoma is a typical glandular adenocarcinoma, usually well-differentiated. (poznayka.org)
  • Microscopically, it may be an adenocarcinoma or signet-ring cell carcinoma, extensively infiltrating the stomach wall, but due to marked desmoplasia cancer cells may be difficult to find. (poznayka.org)
  • Another change is the subclassification of adenocarcinoma: the definition of bronchioalveolar carcinoma has been restricted to noninvasive tumours. (ersjournals.com)
  • As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
  • Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
  • Squamous cell carcinoma (SCC) in various morphological forms needs to be separated from other epithelial tumors for treatment modality selection. (cytojournal.com)
  • Although OPN expression was identified in a good number of bladder, prostate, and brain tumors, the majority of 6 skin cancers, 11 of 14 salivary gland cancers, 2 thyroid carcinomas, and 23 of 26 breast cancers revealed low OPN positivity or were negative. (aacrjournals.org)
  • [ 2 ] While benign in nature, the significance of trichilemmoma resides in the association with Cowden disease (ie, multiple hamartoma syndrome), nevus sebaceous, and the need to differentiate trichilemmomas from other more aggressive cutaneous tumors, such as trichilemmal carcinoma. (medscape.com)
  • Uncommon malignant tumors of the esophagus are defined as any histological type of malignant esophageal tumors other than the typical squamous cell carcinoma. (tmu.edu.tw)
  • In addition, patients with small cell carcinoma seemed to have worse treatment outcome than those with other histological types of tumors. (tmu.edu.tw)
  • To evaluate their relationship to clinical tumors, we determined phenotypic relationships among these carcinomas, other murine models of breast cancer, and features of luminal tumors in women. (biomedcentral.com)
  • Gastric carcinoma comprises more than 90% of all gastric malignant tumors. (poznayka.org)
  • Although this most common gynecologic cancer carries the best prognosis, it is important to differentiate between the classic endometrioid tumors that tend to be estrogen dependent and well differentiated, from other less common high-risk uterine malignancies, such as uterine papillary serous carcinomas (UPSCs), clear cell carcinomas, mixed mullerian tumors (MMTs), or sarcomas, which appear to have a different biology. (medmuv.com)
  • Despite its pro-apoptotic role, caspase-2-deficient tumors have comparable basal apoptosis levels to wild-type tumors [3, 4]. (nature.com)
  • BACKGROUND: Invasive breast carcinomas (IBC) that strongly express SOX10 are almost always negative for androgen receptor (AR). (bvsalud.org)
  • Invasive carcinoma with measured deepest invasion ≥5 mm, limited to the cervix. (mdwiki.org)
  • A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane. (lookformedical.com)
  • An invasive (infiltrating) CARCINOMA of the mammary ductal system (MAMMARY GLANDS) in the human BREAST. (lookformedical.com)
  • Invasive carcinoma eliminates the regular architecture and can include lympho-vascular space invasion, neurotropism, and infiltration of other tissue components such as muscle or cartilage, demonstrating aggressive behavior of the tumor. (entokey.com)
  • Macroscopically, ulcerative carcinomas are poorly-differentiated adenocarcinomas, which invade deeply into the stomach wall. (poznayka.org)
  • Microscopically, fungating or polypoid carcinomas are well-differentiated adenocarcinomas, commonly papillary type. (poznayka.org)
  • citation needed] The carcinoma is confined to the surface layer (cells lining) of the cervix. (wikipedia.org)
  • The carcinoma has grown into the cervix, but has not spread beyond it (extension to the corpus would be disregarded). (wikipedia.org)
  • Carcinoma cervix is not the only cancer caused by HPV. (cytojournal.com)
  • Metastatic malignant neoplasms to the skin include carcinomas and lymphomas. (nih.gov)
  • Kasuganti D, Cimbaluk D, Gattuso P. Lymph node metastasis of large-cell carcinoma of the lung in a seventeen-year-old patient: diagnosis by fine-needle aspiration. (rush.edu)
  • The large cell carcinoma class has been enriched with several variants, including the LCNEC and the basaloid carcinoma, both with a dismal prognosis. (ersjournals.com)
  • Our studies demonstrate that prolactin can promote diverse carcinomas in mice, many of which resemble luminal breast cancers, providing a novel experimental model to examine the pathogenesis, progression and treatment responsiveness of this tumor subtype. (biomedcentral.com)
  • Chromosome 17p is frequently involved, which contains the p53 gene known to confer a poor prognosis in endometrial cancers when mutated or deleted, and which plays an important role in the transition to carcinoma from atypical hyperplasia. (medmuv.com)
  • Kirsten (Ki)-ras activating point mutations in codons 12 and 13 have been implicated in the development of atypical endometrial hyperplasias and endometrioid carcinomas in Japanese women, as well as in colon cancers. (medmuv.com)
  • This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. (bvsalud.org)
  • It represents a large group of epithelial lung malignancies which can be divided into two clinical groups: SMALL CELL LUNG CANCER and NON-SMALL-CELL LUNG CARCINOMA . (lookformedical.com)
  • Lung cancer is classified as small cell lung carcinomas (SCLCs) and non-small cell lung carcinomas (NSCLCs). (oncotarget.com)
  • NSCLC is divided into adeno-, squamous- and large cell lung carcinomas, accounting for about 40%, 30% and 10-15% of all lung cancer cases, respectively. (oncotarget.com)
  • OBJECTIVES: I. Evaluate the efficacy of paclitaxel and carboplatin with amifostine on progression free survival and overall survival in patients with metastatic or recurrent epithelial endometrial carcinoma not amenable to surgery or radiotherapy. (knowcancer.com)
  • Adjuvant therapy including irradiation and chemotherapy may be helpful, particular for small cell carcinoma. (tmu.edu.tw)
  • Large cell neuroendocrine carcinoma (LCNEC) is now recognized as a histologically high grade non small cell carcinoma showing histopathological features of neuroendocrine differentiation as well as immunohistochemical neuroendocrine markers. (ersjournals.com)
  • Similarly, under Carcinoma, specific renamed or deleted in later revisions of tumour classifications. (who.int)
  • HPVs of the beta genera (ß-HPV) are risk factors for cutaneous squamous cell carcinoma (cSCC) and may be related to carcinomas originating in other cutaneous sites such as the vulva. (bvsalud.org)
  • Low response rates in immune check-point blockade (ICB)-treated head and neck squamous cell carcinoma (HNSCC) drive a critical need for robust, clinically validated predictive biomarkers. (bvsalud.org)
  • Carcinoma, Colorectal. (booksdo.com)
  • The study is based on recent observations demonstrating that in vitro cancer cell lines are resistant to cytotoxic drugs when they express high basal levels of p21(WAF1/CIP1) protein, and that the loss of the p21 gene in the HCT116 human colorectal cancer cell line results in increased radioresponse of xenografts derived from that cell line. (elsevierpure.com)
  • Purpose: The study investigated whether basal, constitutive levels of p21(WAF1/CIP1) protein in murine carcinoma are related to in vivo tumor radioresponse. (elsevierpure.com)
  • carcinoma contains abundant pools of mucin in which are seen a small number of tumor cells, sometimes having signet-ring appearance. (poznayka.org)
  • Este tumor se originó espontáneamente como carcinoma del pulmón en un ratón C57BL. (bvsalud.org)
  • Finally, a new class was defined called carcinoma with pleomorphic, sarcomatoid, or sarcomatous elements, which brings together a number of proliferations characterized by a spectrum of epithelial to mesenchymal differentiation. (ersjournals.com)
  • Also called intraductal carcinoma or stage 0 breast cancer, its considered a noninvasive breast cancer. (breastcancertalk.net)
  • Although the male population has a higher prevalence of oropharyngeal cancer, future counts will depend on tobacco and alcohol consumption behavior, which is the major risk factor for oropharyngeal carcinoma, followed by occupational and environmental pollutants and endogenous risks. (entokey.com)
  • An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. (lookformedical.com)