Arterial pressureBaroreceptorsStimulationArteryReflexNerveCardiacNasalGlossopharyngealSyncopeHypertensive patientsSpontaneousHypertensionManipulationImpairmentPredisposePosteriorRegulationPatientsSolitary nucleusHeart rateRegulateMassageBodiesComplicationsHistologicalCardiovascularCerebralNeckInsightsSurgicalActivationDeviceFunctionPressure
Arterial pressure1
- During surgery, the perfect keeping the electrodes within the carotid sinus is definitely assessed based on maximal reductions in arterial pressure and heartrate during electrical activation from the carotid baroreflex [9]. (scienceexhibitions.org)
Baroreceptors9
- The carotid sinus is the reflex area of the carotid artery, consisting of baroreceptors which monitor blood pressure. (wikipedia.org)
- The carotid sinus contains numerous baroreceptors which function as a "sampling area" for many homeostatic mechanisms for maintaining blood pressure. (wikipedia.org)
- The carotid sinus baroreceptors are innervated by the carotid sinus nerve, which is a branch of the glossopharyngeal nerve (CN IX). (wikipedia.org)
- Stimulation of baroreceptors at the carotid sinus can be used to treat resistant hypertension via activation of the baroreflex. (wikipedia.org)
- Carotid sinus reflex death is a potential etiology of sudden death in which manual stimulation of the carotid sinus allegedly causes strong glossopharyngeal nerve (Vagus nerve is for aortic arch baroreceptors) impulses leading to terminal cardiac arrest. (wikipedia.org)
- Changes in stretch and transmural pressure are detected by baroreceptors in the heart, carotid sinus, aortic arch, and other large vessels. (medscape.com)
- Baroreceptors: These are specialized sensory receptors located in the walls of certain blood vessels, particularly in the carotid sinus (located in the carotid artery) and the aortic arch (located at the beginning of the aorta, the main artery of the body). (openai.com)
- The BAROSTIM NEO™ implantable pulse generator is implanted below the collar bone and is connected to a lead that attaches to the carotid artery in the neck, targeting its baroreceptors. (implantable-device.com)
- Using patch-clamping techniques we discovered Rheoreceptors in the carotid sinuses and identified paracrine-endothelial, and autocrine ionic and oxidative processes that are powerful modulators of neurosensory activity, as well as increased reactive oxygen derived free radicals, that suppress baroreceptors in hypertension and atherosclerosis. (uiowa.edu)
Stimulation8
- The carotid sinus can be oversensitive to manual stimulation, a condition known as carotid sinus hypersensitivity, carotid sinus syndrome or carotid sinus syncope, in which manual stimulation causes large changes in heart rate and/or blood pressure. (wikipedia.org)
- Stimulation of the carotid sinus via a slap or a strike, to induce (usually temporary, but sometimes lethal) loss of consciousness is a self-defense technique, and is often taught in martial arts such as karate. (wikipedia.org)
- Carotid sinus hypersensitivity (CSH) is an exaggerated response to carotid sinus baroreceptor stimulation. (medscape.com)
- The hemodynamic changes following carotid sinus stimulation are independent of body position. (medscape.com)
- We hypothesized that selective manipulation of baroreflex activity through electrical carotid sinus stimulation influences insulin sensitivity by changing muscular glucose delivery. (shengsci.com)
- In this context, ideas related to baroreflex resetting during exercise are emphasized, and the potential improvement in exercise tolerance in cardiovascular disease that might be achieved by electrical stimulation of the carotid sinus nerve is highlighted. (elsevierpure.com)
- This concept clarifies basic mechanisms by which carotid sinus nerve stimulation in patients with drug resistant hypertension or heat failure may be beneficial. (uiowa.edu)
- This work provided a mechanistic background in support of clinical trials of carotid sinus nerve stimulation and carotid body resection in hypertensive patients. (uiowa.edu)
Artery4
- In human anatomy, the carotid sinus is a dilated area at the base of the internal carotid artery just superior to the bifurcation of the internal carotid and external carotid at the level of the superior border of thyroid cartilage. (wikipedia.org)
- The carotid sinus extends from the bifurcation to the "true" internal carotid artery. (wikipedia.org)
- In CSH, mechanical deformation of the carotid sinus (located at the bifurcation of the common carotid artery) leads to an exaggerated response with bradycardia or vasodilatation, resulting in hypotension, presyncope, or syncope. (medscape.com)
- Patients are contraindicated if they have been assessed to have bilateral carotid bifurcations located above the level of the mandible, baroreflex failure or autonomic neuropathy, uncontrolled symptomatic cardiac bradyarrhythmias, carotid atherosclerosis that is determined by ultrasound or angiographic evaluation greater than 50%, ulcerative plaques in the carotid artery as determined by ultrasound or angiographic evaluation, known allergy to silicone or titanium. (cvrx.com)
Reflex7
- Carotid sinus syndrome is a temporary loss of consciousness that sometimes accompanies convulsive seizures because of the intensity of the carotid sinus reflex when pressure builds in one or both carotid sinuses. (wikipedia.org)
- Carotid sinus reflex death has been pointed out as a possible cause of death in cases of strangulation, hanging and autoerotic strangulation, but such deductions remain controversial. (wikipedia.org)
- The carotid sinus reflex plays a central role in blood pressure homeostasis. (medscape.com)
- 1. The effects of acute blood volume change in conscious rabbits on a.c. gain of the carotid baroreceptor reflex with respect to heart rate, blood pressure, cardiac output and systemic vascular resistance were studied. (portlandpress.com)
- 4. Thus control of blood pressure by the carotid sinus reflex is remarkably unaffected by acute change in blood volume, and is impaired only when there is depression of gain for cardiac output without a concomitant rise in gain for systemic vascular resistance. (portlandpress.com)
- The baroreflex, also known as the baroreceptor reflex, is a physiological mechanism that helps regulate blood pressure within the body. (openai.com)
- Afferents of the SN mediate the gag reflex , the carotid sinus reflex, the aortic reflex, the cough reflex , the baroreflex and chemoreceptor reflexes, several respiratory reflexes and reflexes within the gastrointestinal system regulating motility and secretion. (wikipedia.org)
Nerve3
- On the left side, the nerve enters the thorax between the left primitive carotid and the subclavian, and it converges at the deep part of the cardiac plexus. (medscape.com)
- Chemoreceptors and mechanoreceptors of the general visceral afferent pathway (GVA) from the carotid body and carotid sinus via (the carotid sinus nerve of) the glossopharyngeal nerve (CN IX), and from aortic bodies and sinoatrial node via the vagus nerve (CN X). (wikipedia.org)
- [3] Additional minor GVA input from the nasal cavity, soft palate and sinus cavities enters via the facial nerve. (wikipedia.org)
Cardiac2
- On the right side, it descends behind the primitive carotid to constitute the dorsal part of the cardiac plexus. (medscape.com)
- Once the target HR was achieved, subjects exercised for 6-8 min to assure steady-state conditions before the transfer function analysis, spontaneous baroreflex analysis and static carotid-cardiac baroreflex function were assessed. (churup.com)
Nasal2
- More procedures than ever have been removed from the CMS inpatient-only list, including 2019 newcomers like surgical nasal and sinus endoscopies (CPT 31241), implantation or replacement of carotid sinus baroreflex device (CPT 0266T), and anesthesia for extensive spine and spinal cord procedures (CPT 00670). (anesthesiaexperts.com)
- Find out what products are available best free left 4 dead 2 cheats sinus and nasal problems. (churup.com)
Glossopharyngeal1
- Afferent impulses are transmitted by the carotid sinus, glossopharyngeal, and vagus nerves to the nuclei tractus solitarius and the para median nucleus in the brain stem. (medscape.com)
Syncope2
- Massage of the carotid sinus, carotid sinus massage is used to diagnose carotid sinus syncope and is sometimes useful for differentiating supraventricular tachycardia (SVT) from ventricular tachycardia. (wikipedia.org)
- Spontaneous carotid sinus syndrome is rare and accounts for about 1% of causes of syncope. (medscape.com)
Hypertensive patients1
- We enrolled 16 hypertensive patients who responded to treatment with an electrical carotid sinus stimulator. (shengsci.com)
Spontaneous1
- The term spontaneous carotid sinus syndrome refers to a clinical situation in which the symptoms can be clearly attributed to a history of accidental mechanical manipulation of the carotid sinuses (eg, taking pulses in the neck, shaving) and CSH is reproduced by carotid sinus massage. (medscape.com)
Hypertension5
- This can be used therapeutically in treatment of resistant hypertension by baroreflex activation. (wikipedia.org)
- Doumas M, Faselis C, Tsioufis C, Papademetriou V. Carotid baroreceptor activation for the treatment of resistant hypertension and heart failure. (gwu.edu)
- Baroreflex-mediated changes in sympathetic vasomotor tone may have a limited acute effect on muscle glucose metabolism in patients with treatment-resistant hypertension. (shengsci.com)
- Labile hypertension is a vascular disease commonly associated with disorders in autonomic regulation such as baroreflex failure, where the baroreflex input that helps stabilize blood pressure is prevented from traveling from the carotid sinus to the nucleus tractus solitarii. (veincenter.doctor)
- Clinical Tests of BAT in Resistant Hypertension Device-Based Therapy of Hypertension Trial (DEBuT-HT) Confirming EKB-569 earlier experimental research [10, 11], a first-in-human proof-of-concept research from the Rheos program indicated that severe electrical activation from the carotid sinus in individuals going through elective carotid medical procedures elicits significant and instant reductions in blood circulation pressure and heartrate [12]. (scienceexhibitions.org)
Manipulation1
- Third, are there any pathophysiological conditions in which manipulation of baroreflexes or baroreflex 'dysfunction' might alter exercise responses? (elsevierpure.com)
Impairment2
- [ 8 ] Data have been reported on neuronal degeneration with accumulation of hyperphosphorylated tau or alpha-synuclein in neurones in medulla, leading to impairment of central regulation of baroreflex responses and predispose elderly patients to CSH. (medscape.com)
- for the GDS group, Impairment in Baroreflex Sensitivity in Recent-Onset Type 2 Diabetes Without Progression Over 5 Years. (diabetesjournals.org)
Predispose1
- Since these plaques, if large and unstable, predispose to ischemic strokes and transient ischemic attacks, carotid endarterectomies are frequently done for prophylaxis. (wikipedia.org)
Posterior2
- Herein, we wish to highlight paramount anatomical, clinical, and stent placement considerations related to DSS located in the dural venous sinus at the posterior cranial fossa and the interventional complications caused by the presence of this variation during stenting procedures. (bvsalud.org)
- The technique of posterior approach used in this study was found to have a higher rate of success in cannulation and lower rate of complication such as carotid puncture. (lookformedical.com)
Regulation2
- First, do baroreflexes contribute to arterial blood pressure regulation during exercise? (elsevierpure.com)
- Second, if baroreflexes contribute to blood pressure regulation during exercise, how do they do it? (elsevierpure.com)
Patients2
- Endoscopic sinus surgery (ESS) is considered a selective treatment method and is widely performed in chronic sinusitis patients who do not respond to drug treatment. (ekja.org)
- Sixty-eight patients with the American Society of Anesthesiologists physical status class I or II diagnosed with chronic sinusitis and scheduled to receive endoscopic sinus surgery were chosen as subjects. (ekja.org)
Solitary nucleus2
- The neurons which innervate the carotid sinus centrally project to the solitary nucleus in the medulla of the brainstem. (wikipedia.org)
- [ 1 ] The solitary nucleus, being an integrating hub for the baroreflex, receives sensory input about the state of the cardiovascular system. (medscape.com)
Heart rate2
- The predominant manifestation is a decreased heart rate, which results in sinus bradycardia, atrioventricular block, or asystole due to vagal action on sinus and atrioventricular nodes. (medscape.com)
- Overall, the baroreflex helps maintain stable blood pressure by constantly adjusting heart rate and blood vessel diameter in response to changes in blood pressure. (openai.com)
Regulate2
- Arterial baroreflexes may regulate resistance vessels supplying glucose to skeletal muscle by modulating efferent sympathetic nervous system activity. (shengsci.com)
- This paper briefly reviews the historical evolution of ideas about how baroreflexes operate and continue to regulate arterial blood pressure during exercise. (elsevierpure.com)
Massage2
- Medical literature examining the use of carotid sinus massage involving brief gentle pressure of the carotid sinus in therapeutic settings as a diagnostic and therapeutic examination tool have reported few potentially fatal complications. (wikipedia.org)
- A carotid massage can also possibly dislodge a thrombus, or some plaque. (wikipedia.org)
Bodies1
- Patch-clamping glomus cells of the carotid bodies allowed us to uncover new ionic determinants of sensitivity to hypoxia and low pH. (uiowa.edu)
Complications1
- Recently, an interesting study regarding "Dural sinus septum: an underlying cause of cerebral venous sinus stenting failure and complications. (bvsalud.org)
Histological1
- The anatomical and histological evaluation of the intraluminal trabeculae within this sinus were evaluated. (bvsalud.org)
Cardiovascular1
- Impaired baroreflex sensitivity (BRS) predicts cardiovascular mortality and is prevalent in long-term diabetes. (diabetesjournals.org)
Cerebral1
- Physical assault at this point, producing massive baroreflex activation can cause dramatic falls in blood pressure and cerebral ischemia. (wikipedia.org)
Neck2
- These cervical ganglia go down the primitive carotid and in front of the large muscles of the neck. (medscape.com)
- Anxiety, depression, panic attacks , allergy, digestive disorders, chronic sinus pain, balance problems caused by inner ear fluids, (please see my article Neck Pain Chronic Sinusitis and Eustachian Tube Dysfunction ,) and cough. (caringmedical.com)
Insights1
- Stay up-to-date on the latest news, insights and best practices on Barostim Baroreflex Activation Therapy. (cvrx.com)
Surgical2
- Rheos Program and Surgical Implantation The first-generation Rheos program for activation from the carotid baroreflex includes stimulating electrodes linked to a pulse generator implanted subcutaneously in the infraclavicular area. (scienceexhibitions.org)
- Reduction of intraoperative bleeding is necessary to achieve the ideal surgical field for the endoscopic sinus surgery (ESS). (ekja.org)
Activation3
- This is the mechanism of baroreflex activation therapy. (wikipedia.org)
- Carotid baroreceptor activation for the treatment of resistant hyperte" by Michael Doumas, Charles Faselis et al. (gwu.edu)
- This enables for managed current delivery during the day, such as the possibility of offering personalized patterns of baroreflex activation. (scienceexhibitions.org)
Device1
- Recent specialized advances have resulted in the introduction of a medical device that may reliably activate the carotid baroreflex with a satisfactory amount of safety. (scienceexhibitions.org)
Function1
- Although baroreceptor function usually diminishes with age, some people experience hypersensitive carotid baroreflexes. (medscape.com)
Pressure2
- Aims Mayer waves are low frequency blood pressure waves, whose modulation involves central/peripheral baroreflex pathways. (tcd.ie)
- The mechanosensors PIEZO1 and 2 are important determinants of blood pressure and the baroreflex. (uiowa.edu)