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  • BF638R
  • However, disruption of feoAB also diminished the capacity of BF638R to grow in a mouse intraperitoneal abscess model, suggesting that inorganic ferrous iron assimilation is essential for B. fragilis survival in vivo. (nih.gov)
  • pathogenic
  • Selection for feoAB mutations as a result of metronidazole treatment will disable the pathogenic potential of B. fragilis and could contribute to the clinical efficacy of metronidazole. (nih.gov)
  • susceptible
  • In general, B. fragilis is susceptible to metronidazole, carbapenems, tigecycline, beta-lactam/beta-lactamase inhibitor combinations (e.g. (wikipedia.org)
  • treatment
  • Provided is an application of bacteroides fragilis in prevention and/or treatment of meningitis, in particular, an application of the bacteroides fragilis in preparation of medicines, pharmaceutical compositions, food, health care products, and food additives for preventing and/or treating meningitis. (wipo.int)
  • enzyme
  • The cloned gene, designated katB, encoded a catalase enzyme with electrophoretic mobility identical to that of the purified protein from the B. fragilis parental strain. (ecu.edu)
  • The active-site residues, proximal and distal hemebinding ligands, and NADPH-binding residues of the bovine liver catalase-type enzyme were highly conserved in B. fragilis KatB. (ecu.edu)
  • Fragilysin (EC 3.4.24.74, Bacteroides fragilis (entero)toxin) is an enzyme. (wikipedia.org)