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  • bacteria
  • This underlying chronic infection leaves COPD patients particularly vulnerable to acute viral infections, which further destabilize host immunity to bacteria. (frontiersin.org)
  • Due to the increasing emergence of antibiotic-resistant strains of enteropathogenic bacteria, development of alternative treatments to fight against gut infections is a major health issue. (frontiersin.org)
  • As far as parasites and bacteria infection usure. (backyardchickens.com)
  • The absence of integrins or impaired PMN activation results in diminished responses to a number of pathogens, including bacteria such as Staphylococcus aureus , fungal infections such as Aspergillus fumigatus , and protozoan infection by Toxoplasma gondii ( 7 - 10 ). (jimmunol.org)
  • Upon reaching the site of the infection, PMNs phagocytose Ig-opsonized foreign particles, such as bacteria or fungi, via Fc receptors or complement-opsonized particles through integrins for degradation in lysosomes ( 1 , 13 - 15 ). (jimmunol.org)
  • It is often seen in infections with C. perfringens or any of myriad soil-borne anaerobic bacteria. (wikipedia.org)
  • Gangrenous infection by soil-borne bacteria was common in the combat injuries of soldiers well into the 20th century, because of nonsterile field surgery and the basic nature of care for severe projectile wounds. (wikipedia.org)
  • Opportunistic infection may be caused by microbes ordinarily in contact with the host, such as pathogenic bacteria or fungi in the gastrointestinal or the upper respiratory tract, and they may also result from (otherwise innocuous) microbes acquired from other hosts (as in Clostridium difficile colitis) or from the environment as a result of traumatic introduction (as in surgical wound infections or compound fractures). (wikipedia.org)
  • When viruses, including bacteriophages (viruses that infect bacteria), infect bacterial cells, their normal mode of reproduction is to harness the replicational, transcriptional, and translation machinery of the host bacterial cell to make numerous virions, or complete viral particles, including the viral DNA or RNA and the protein coat. (wikipedia.org)
  • Blisters and sores appear on numb areas of the feet and legs such as metatarso-phalangeal joints, heel region and as a result pressure or injury goes unnoticed and eventually become portal of entry for bacteria and infection. (wikipedia.org)
  • The three main causes of vaginitis are infections by bacteria (bacterial vaginosis), yeast (vaginal candidiasis), or the protozoan that causes trichomoniasis. (wikipedia.org)
  • Although the fecal content and high bacterial loads of the intestine are normally safely contained, progressive ischemia causes to tissue breakdown and inevitably leads to bacteria spreading to the bloodstream. (wikipedia.org)
  • pathogens
  • M-CSF treatment during engraftment or after infection efficiently protected from these pathogens as early as 3 days after transplantation and was effective as a single dose. (rupress.org)
  • Since approximately 80% of infectious diseases are known to be transmitted by touch, and pathogens found in healthcare facilities can survive on inanimate surfaces for days and even months, the microbial burden of frequently touched surfaces is believed to play a significant role in infection causality. (wikipedia.org)
  • In Chile, 70,000 nosocomial infections are reported each year, most commonly from common hospital-borne pathogens such as S. aureus, P. aeruginosa and A.baumanii. (wikipedia.org)
  • To get around the usage annoyance, it is common for health professionals to speak of colonization (rather than infection) when they mean that some of the pathogens are present but that no clinically apparent infection (no disease) is present. (wikipedia.org)
  • clinically
  • Hematopoiesis from the transplanted hematopoietic stem cells (HSCs) and progenitor cells (HS/PCs) occurs with a significant lag phase, in which the patient shows severe myeloid cytopenia and is vulnerable to severe and potentially lethal infections, for example by the clinically important gram-negative bacterium Pseudomonas aeruginosa or the fungus Aspergillus fumigatus . (rupress.org)
  • The word infection can denote any presence of a particular pathogen at all (no matter how little) but also is often used in a sense implying a clinically apparent infection (in other words, a case of infectious disease). (wikipedia.org)
  • causative
  • Further, there are complications which lead to daily discomfort such as: persistent discomfort superficial skin infection (from scratching) complications of the causative condition (such as gonorrhea and candida infection) Vaginitis is the disruption of the healthy vaginal microbiota. (wikipedia.org)
  • strains
  • Clinical trials are being conducted on microbial strains unique to individual healthcare facilities around the world to evaluate to what extent copper alloys can reduce the incidence of infection in hospital environments. (wikipedia.org)
  • Taksta (previously CEM-102) is a front-loaded oral dosing regimen of sodium fusidate under development in the U.S. as an antibiotic for gram-positive infections including drug-resistant strains such as methicillin-resistant Staphylococcus aureus (MRSA). (wikipedia.org)
  • The first colistin-resistance gene in a plasmid which can be transferred between bacterial strains was found in 2011 in China and became publicly known in November 2015. (wikipedia.org)
  • genes
  • We compared the cellular processes after infection in each anatomical site by confocal fluorescence imaging and determined the implication of inflammatory immune genes by measuring gene expression by qPCR. (frontiersin.org)
  • At the same time, some phage genes are left behind in the bacterial chromosome. (wikipedia.org)
  • Specialized transduction occurs when the prophage excises imprecisely from the chromosome so that bacterial genes lying adjacent to the prophage are included in the excised DNA. (wikipedia.org)
  • antibiotics
  • Physical factors that have been claimed to contribute to the development of infections include the following: constantly wet vulva due to tight clothing, chemicals coming in contact with the vagina via scented tampons, antibiotics, birth control pills, or a diet favoring refined sugar and yeast. (wikipedia.org)
  • innate
  • Polymorphonuclear leukocytes or neutrophils (PMNs) are an essential component of the innate host defense response and are often the first cells to respond to an infection ( 1 ). (jimmunol.org)
  • treatment
  • treatment of infected, human bronchial 16-HBE cells with 25(OH)D liposomes however resulted in a significant reduction in bacterial survival. (ljmu.ac.uk)
  • Available data suggests that individuals with higher bacterial infection loads are less likely to resolve infection following a single dose of treatment, and thus remain a source of re-emergent infection following treatment. (biomedcentral.com)
  • The findings from our mathematical model suggest that implementing the new double-dose strategy for 5 years or less was predicted to control infection more successfully than annual or 6-monthly treatment. (biomedcentral.com)
  • Infection was controlled more readily if treatment was combined with enhanced F&E. The results appeared robust to variation in a number of key epidemiological parameters. (biomedcentral.com)
  • Despite advances in antimicrobial treatment and increased availability of health facilities, the outcome in infants with serious bacterial infection remains poor [ 4 ]. (plos.org)
  • Many infants with serious bacterial infection never reach treatment facilities and the case fatality for those who do, range from 13% to 69% [ 4 ]. (plos.org)
  • Jun 2011: Taksta may be effective in the treatment of chronic prosthetic joint infections and osteomyelitis. (wikipedia.org)
  • A randomized, double-blind Phase 2 study comparing the efficacy and safeety of an oral fusidic acid loading-dose regimen to oral linezolid in the treatment of acute bacterial skin and skin structure infections. (wikipedia.org)
  • Recent studies have found that the cause of chronic sinus infections lies in the nasal mucus, not in the nasal and sinus tissue targeted by standard treatment. (wikipedia.org)
  • Without treatment, the average survival time after infection is 11 years. (wikipedia.org)
  • Without treatment, this second stage of the natural history of HIV infection can last from about three years to over 20 years (on average, about eight years). (wikipedia.org)
  • While the exact association between trichomoniasis infection and HIV genital shedding has not been consistently demonstrated, "there is good evidence that TV treatment reduces HIV genital shedding. (wikipedia.org)
  • Vaginal infections often have multiple causes (varies between countries between 20 and 40% of vaginal infections), which present challenging cases for treatment. (wikipedia.org)
  • viruses
  • This detailed biochemical study of a new branch of the CRISPR-Cas defense systemone that targets RNA moleculeshas shed light on a powerful weapon in the bacterial arsenal against invading viruses and mobile elements," says Michael Bender, who oversees RNA processing and function grants at the National Institutes of Health's National Institute of General Medical Sciences. (infectioncontroltoday.com)
  • larvae
  • We used an early-embryo infection model at 3 days post-fertilization (dpf) through the microinjection of A. hydrophila into the duct of Cuvier, caudal vein, notochord, or muscle and two bath infection models using 4 dpf healthy and injured larvae. (frontiersin.org)
  • inflammatory
  • Bowel obstruction is most often caused by intestinal adhesions, which frequently form after abdominal surgeries, or by chronic infections such as diverticulitis, hepatitis, and inflammatory bowel disease. (wikipedia.org)
  • sinus
  • Maxillary sinusitis is common due to the close anatomic relation of the frontal sinus, anterior ethmoidal sinus and the maxillary teeth, allowing for easy spread of infection. (wikipedia.org)
  • Furthermore, the drainage orifice lies near the roof of the sinus, and so the maxillary sinus does not drain well, and infection develops more easily. (wikipedia.org)
  • tissues
  • Gas gangrene (also known as clostridial myonecrosis and myonecrosis) is a bacterial infection that produces gas in tissues in gangrene. (wikipedia.org)
  • Infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce. (wikipedia.org)
  • confocal
  • We now establish that such polyreactive preparations bind efficiently to Salmonella enterica Typhimurium and trigger bacterial agglutination, as observed by laser scanning confocal microscopy. (frontiersin.org)
  • Therefore
  • Therefore, during Mtb infection, IL-27R acts intrinsically on T cells to limit protection and reduce fitness, whereas the IL-27R-deficient environment alters the phenotype and location of T cells. (rupress.org)
  • fatal
  • When you have chronic disease like HIV, liver problems, you're predisposed, and infection could form and it could be fatal," said WDSU medical editor Dr. Corey Hebert. (wdsu.com)
  • This can be especially troublesome in hospital environments where patients with immunodeficiencies are at enhanced risk for contracting nosocomial infections (hospital-acquired infection), often with fatal consequences. (wikipedia.org)
  • vascular
  • After adhesion, PMNs then migrate through the vascular endothelium to the site of the infection, following gradients of chemokines ( 11 , 12 ). (jimmunol.org)
  • Risk factors implicated in the development of diabetic foot ulcers are infection, older age, diabetic neuropathy, peripheral vascular disease, cigarette smoking, poor glycemic control, previous foot ulcerations or amputations, and ischemia of small and large blood vessels. (wikipedia.org)
  • cause
  • AIDS was first recognized by the United States Centers for Disease Control and Prevention (CDC) in 1981 and its cause-HIV infection-was identified in the early part of the decade. (wikipedia.org)
  • They can create a gateway for infection as well as cause wound edge deterioration preventing wound closure. (wikipedia.org)
  • The disruption of the normal microbiota can cause a vaginal yeast infection. (wikipedia.org)
  • further
  • The newspaper notes, "Further research must be done to draw a direct connection between these changes in the microbiome and subsequent HIV infection" (Morin, 4/15). (kff.org)
  • resistant
  • The microbiological success in each ME population with methicillin-resistant S. aureus (MRSA) infection is 100 percent (99/99) at both the EOT and PTE visits. (wikipedia.org)
  • vulnerability
  • The idea of the werewolf's supposed vulnerability to silver probably dates back to the legend of the Beast of Gévaudan, in which a gigantic wolf is killed by a hunter with the name of "Argent" which is Latin for silver, wielding a gun loaded with silver bullets. (wikipedia.org)
  • particles
  • If the lysogen is induced (by UV light for example), the phage genome is excised from the bacterial chromosome and initiates the lytic cycle, which culminates in lysis of the cell and the release of phage particles. (wikipedia.org)