• Studies of phospholipid-requiring bacterial enzymes. (wikipedia.org)
  • Genes in region A encode enzymes for biosynthesis of the capsular polysaccharide, and genes in regions B and C are implicated in the translocation of the high molecular weight polysaccharides to the cell surface. (cdc.gov)
  • The deduced amino acid sequences of these ORFs showed a high degree of homology to the deduced amino acid sequences of the rfbC, rfbD, rfbA, and rfbB genes of Salmonella typhimurium LT2, which have been shown to encode a set of enzymes responsible for conversion of glucose 1-phosphate to dTDP-rhamnose. (uni-bielefeld.de)
  • protein_coding" "AAC74185","ptsG","Escherichia coli","fused glucose-specific PTS enzymes: IIB component/IIC component [Ensembl]. (ntu.edu.sg)
  • Her main research interests have been the study of Mur ligases from different bacterial species and the search for inhibitors of these enzymes. (degruyter.com)
  • His main research interests concern the identification of genes and enzymes involved in this pathway, the regulation of this metabolism, the mode of action of antibiotics and bacteriocins interfering with this pathway and the corresponding resistance mechanisms, as well as the molecular bases for the recognition of bacterial cell-wall peptidoglycan by host innate immunity mechanisms. (degruyter.com)
  • For more than 30 years, his main research interests have been the functional and structural study of the enzymes of peptidoglycan biosynthesis, the determination of the structure of peptidoglycan from certain bacterial species, and the search for peptidoglycan biosynthesis inhibitors that could act as antibacterial agents. (degruyter.com)
  • The synthesis of the peptide stem of bacterial peptidoglycan involves four enzymes, the Mur ligases (MurC, D, E and F). Among them, MurD is responsible for the ATP-dependent addition of d -glutamic acid to UDP-MurNAc- l -Ala, a reaction which involves acyl-phosphate and tetrahedral intermediates. (degruyter.com)
  • Like most enzymes of peptidoglycan biosynthesis, MurD constitutes an attractive target for the design and synthesis of new antibacterial agents. (degruyter.com)
  • In enzymology, a lipopolysaccharide glucosyltransferase I (EC 2.4.1.58) is an enzyme that catalyzes the chemical reaction UDP-glucose + lipopolysaccharide ⇌ {\displaystyle \rightleftharpoons } UDP + D-glucosyl-lipopolysaccharide Thus, the two substrates of this enzyme are UDP-glucose and lipopolysaccharide, whereas its two products are UDP and D-glucosyl-lipopolysaccharide. (wikipedia.org)
  • The systematic name of this enzyme class is UDP-glucose:lipopolysaccharide glucosyltransferase. (wikipedia.org)
  • Other names in common use include UDP-glucose:lipopolysaccharide glucosyltransferase I, lipopolysaccharide glucosyltransferase, uridine diphosphate glucose:lipopolysaccharide glucosyltransferase, I, and uridine diphosphoglucose-lipopolysaccharide glucosyltransferase. (wikipedia.org)
  • This enzyme participates in lipopolysaccharide biosynthesis and glycan structures - biosynthesis 2. (wikipedia.org)
  • 3. Purification and properties of uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I". J. Biol. (wikipedia.org)
  • Biosynthesis of bacterial lipopolysaccharide. (wikipedia.org)
  • camPestris is involved in lipopolysaccharide (1,PS) biosynthesis. (uni-bielefeld.de)
  • 2. Maxwell, E.S. and de Robichon-Szulmajster, H. Purification of uridine diphosphate galactose-4-epimerase from yeast and the identification of protein-bound diphosphopyridine nucleotide. (qmul.ac.uk)
  • MS = An enzyme that catalyzes the transfer of UMP from UDPglucose to galactose 1-phosphate, forming UDPgalactose and glucose 1-phosphate. (doctorinternet.com)
  • This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. (unl.edu)
  • This enzyme produces sucrose 6-phosphate and UDP from UDP-glucose and D-fructose 6-phosphate, and may be encoded near the gene for fructokinase. (unl.edu)
  • Sucrose synthases catalyze the synthesis of sucrose from UDP-glucose and fructose. (unl.edu)
  • Serogroup-specific capsule biosynthesis genes located in region A have been published for serogroup X, and nucleotide sequences for serogroups E, L, and Z have been submitted to GenBank (accession nos. (cdc.gov)
  • Bacterial RNA polymerase (RNA Pol) can initiate transcription in vitro by accepting nucleotide metabolites capped with flavin adenine dinucleotide (FAD), uridine diphosphate glucose (UDP-Glc), and uridine diphosphate N-acetylglucosamine (UDP-GlcNAc). (biosyn.com)
  • Sucrose plus UDP (or ADP) becomes D-fructose plus UDP-glucose (or ADP-glucose), which is then available for cell wall (or starch) biosynthesis. (unl.edu)
  • Bacterial genomes show great diversity in size and composition, and this diversity is the result of millions of years of horizontal gene transfer and other complex evolutionary events [ 5 , 6 ]. (biomedcentral.com)
  • In a comparisonof the first two bacterial genomes sequenced, Mushegian and Kooninprojected that the 256 orthologous genes shared by the Gram negativeHaemophilus influenzae and the Gram positive M. genitalium genomes area close approximation of a minimal gene set for bacterial life(2). (fullblog.com.ar)
  • proposed a 206 protein-coding gene core of aminimal bacterial gene set based on analysis of several free-living andendosymbiotic bacterial genomes (3). (fullblog.com.ar)
  • Sucrose synthase is found, so far, exclusively in plants and cyanobacteria [Energy metabolism, Biosynthesis and degradation of polysaccharides]. (unl.edu)
  • This family consists of the N-terminal regions, or in some cases the entirety, of bacterial proteins closely related to plant sucrose-phosphate synthases (SPS). (unl.edu)
  • The antimicrobial wasp Polybia-MP1 peptide selectively kills bacterial cells! (biosyn.com)
  • protein_coding" "Cz09g17180.t1","No alias","Chromochloris zofingiensis","Inosine/uridine-preferring nucleoside hydrolase domain [Interproscan]. (ntu.edu.sg)
  • Bifunctional purine biosynthesis protein PurH-like [Interproscan]. (ntu.edu.sg)
  • Molecular mechanisms involved in N. meningitidis capsule biosynthesis have also been identified, and genes involved in this process and in cell surface translocation are clustered at a single chromosomal locus termed cps . (cdc.gov)
  • Amino acids also contribute to cellular energy metabolism by providing a carbon source for entry into the citric acid cycle (tricarboxylic acid cycle), especially when a primary source of energy, such as glucose, is scarce, or when cells undergo metabolic stress. (wikipedia.org)
  • It is expected that the removal of a number of non-essential regions from a bacterial chromosome will facilitate the optimization of metabolic pathways and energy utilization by enhancing the predictability of genetic engineering, which can improve overall metabolic performance [ 7 ]. (biomedcentral.com)
  • In this review, we discuss the key differences in the structural features of xylans across diverse plant species, how these features affect their interactions with cellulose and lignin, and recent developments in understanding their biosynthesis. (biomedcentral.com)
  • He is director of research at CNRS and, since 2001, is the head of the Laboratory of Bacterial Envelopes and Antibiotics which, for more than 30 years, has been studying the biochemistry, genetics and physiology of the bacterial cell-wall peptidoglycan biosynthesis pathway as a whole. (degruyter.com)
  • For more than 15 years he has been involved in discovery of inhibitors of bacterial cell-wall biosynthesis as potential antibacterial agents. (degruyter.com)
  • Thus, with its lack of genomic redundancy and contingenciesfor different environmental conditions, M. genitalium is already closeto being a minimal bacterial cell. (fullblog.com.ar)
  • Furthermore, our data suggested that cold-seep tubeworm is capable of de novo sterol biosynthesis, as well as incorporation and transformation of cycloartenol and lanosterol into unconventional sterols, and the critical enzyme involved in this process might have properties similar to those in the enzymes from plants or fungi. (biomedcentral.com)
  • They have been shown to be important virulence factors in a number of Gram-negative pathogens and to be involved in the biosynthesis of different polysaccharide structures. (nih.gov)
  • This enzyme participates in lipopolysaccharide biosynthesis and glycan structures - biosynthesis 2. (wikipedia.org)
  • Serves as the biological precursor of insect chitin, of muramic acid in bacterial cell walls, and of sialic acids in mammalian glycoproteins. (nih.gov)
  • The transmembrane chitin synthase transports N-acetylglucosamine residues from uridine diphosphate-N-acetylglucosamine (brown hexagon) to an expanding fibre that is transported across the cell membrane (light blue). (vedantu.com)
  • Glucan and chitin, the two primary structural polysaccharides, are connected together in perfect harmony, but when the natural equilibrium is upset, as could happen after treatment with echinocandin medicines, the chitin biosynthesis pathway reacts by adding more chitin to the wall to strengthen it. (vedantu.com)
  • The higher yield of chitosan was obtained when used glucose as carbon source for all fungal strains. (ijser.org)
  • Molecular mechanisms involved in N. meningitidis capsule biosynthesis have also been identified, and genes involved in this process and in cell surface translocation are clustered at a single chromosomal locus termed cps . (cdc.gov)
  • A b-1,3-glucan synthase (yellow) converts uridine diphosphate-N-glucose (green hexagon) into glucose, which is then transferred to the extruded b-1,3-glucan fibre. (vedantu.com)
  • As the fruit ripens, a dynamic color change is observed from green to yellow to red due to the biosynthesis of pigments like chlorophyll, carotenoids, and anthocyanins. (biomedcentral.com)
  • In contrast, gls2/alg6 double-mutant cells that transfer Man 9 GlcNAc 2 and that are unable to remove the glucose units added by GT as they lack glucosidase II (GII), grew at 37°C and had, when grown at 28°C, a phenotype of growth and morphology almost identical to that of wild-type cells. (rupress.org)
  • 16S rRNA was used to detect composition changes in the intestinal bacterial community of animals after treatment with hydroxyurea. (thno.org)