- aureus
- The name S. intermedius was proposed for isolates that differed from Staphylococcus aureus in various biochemical reactions and with regard to cell wall composition (Hajek 1976). (scielo.org.za)
- Similar to S. aureus colonisation seen in humans, healthy dogs frequently carry S. intermedius as part of their normal microflora. (scielo.org.za)
- Although information regarding the pathogenic process of S. pseudintermedius is limited, the bacterium is known to possess virulence factors similar to those found in S. aureus , including a leukotoxin comparable to the Panton-Valentine leukocidase associated with community-acquired S. aureus infection ( 1 ). (cdc.gov)
- The emergence of livestock-associated methicillin-resistant Staphylococcus aureus and the description of a novel methicillin-resistant gene, mecC, have renewed concerns regarding the role of animals as reservoirs and a source for the evolution of novel, virulent zoonotic pathogens. (intechopen.com)
- Staphylococcus aureus is the most significant species within this genus by virtue of its versatility as a pathogen in humans and animals [ 4 , 5 ]. (intechopen.com)
- Two species were described in 2015 - Staphylococcus argenteus and Staphylococcus schweitzeri - both of which were previously considered variants of S. aureus. (wikipedia.org)
- These species belong to two separate groups - the S. aureus (S. aureus alone) group and the S. hyicus-intermedius group (the remaining five). (wikipedia.org)
- Staphylococcus aureus infections of the skin and soft tissue pose a major concern to public health, largely owing to the steadily increasing prevalence of drug resistant isolates. (lpmhealthcare.com)
- Recently we have used bioengineering strategies to enhance the activity of nisin against several high profile targets, including multi-drug resistant clinical pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) and also against staphylococci and streptococci associated with bovine mastitis. (nih.gov)
- Það var Sir Alexander Ogston , skoskur læknir og prófessor við Háskólann í Aberdeen , sem fyrstur lýsti tegundinni sem í dag kallast Staphylococcus aureus og sýndi fram á að hún getur valdið sýkingum í mönnum árið 1880 . (wikipedia.org)
- Staphylococcus aureus, especially methicillin-resistant S. aureus (MRSA), is a significant pathogen in both human medicine and veterinary medicine. (hindawi.com)
- Longitudinal studies in humans distinguish between at least three carriage patterns of Staphylococcus aureus in healthy individuals: persistent carriage, intermittent carriage, and noncarriage. (hindawi.com)
- Detection of methicillin-resistant S. aureus (MRSA) represents the most important task in determining the antimicrobial susceptibilities of staphylococci. (asmscience.org)
- methicillin-resistant Staphylococcus pseudintermedius
- However, newly emerging pathogens such as methicillin resistant Staphylococcus pseudintermedius (MRSP) pose a significant threat in terms of veterinary health and as a reservoir for antibiotic resistance determinants. (nih.gov)
- Against this backdrop, methicillin-resistant Staphylococcus pseudintermedius (MRSP) has emerged over the last decade as a critically important, opportunistic canine pathogen responsible for skin, soft tissue, and surgical site infections . (nih.gov)
- In this study, we treated bacterial biofilms produced by methicillin-resistant Staphylococcus pseudintermedius (MRSP) with a combination of fosfomycin and clarithromycin. (biomedcentral.com)
- MRSP
- Of concern is the emergence and widespread international recognition of methicillin-resistant S. pseudintermedius (MRSP) ( 1 ). (cdc.gov)
- The potential for zoonotic transmission and concerns that MRSP could be mistaken for other methicillin-resistant staphylococci ( 1 , 2 ) suggest the need for further investigation into the epidemiology of this pathogen. (cdc.gov)
- At the end of my study I also analysed the clinical implications of methicillin-resistant S. pseudintermedius (MRSP) infections using as an example the isolation of this microorganism from a pyoderma lesion in a dog that underwent various antibiotic treatments before the correct diagnosis was made and an appropriate antibiotic treatment was administered. (unibas.ch)
- species
- Staphylococcus species are facultatively anaerobic, Gram-positive, coccal bacteria that belong to the family Micrococcaceae (Rich 2005). (scielo.org.za)
- Staphylococcus pseudintermedius is a coagulase-positive species in the S. intermedius group. (cdc.gov)
- Previously misidentified as S. intermedius , S. pseudintermedius is now recognized as a leading cause of opportunistic infection in dogs ( 1 ) and a cause of sporadic infections in other species, including humans ( 1 , 2 ). (cdc.gov)
- Staphylococci are natural residents on the skin and mucous membranes of a wide range of host species [ 1 ]. (intechopen.com)
- Other Staphylococcus species, collectively termed coagulase-negative staphylococci (CNS), are responsible for a variety of opportunistic infections in humans and animals [ 11 ]. (intechopen.com)
- Due to the ubiquity of many of the species within this group, their clinical significance has traditionally been dismissed, and when isolated from clinical specimens, the bacteria have merely been regarded as contaminants [ 12 ]. (intechopen.com)
- The Staphylococcus genus includes at least 40 species. (wikipedia.org)
- A new coagulase negative species - Staphylococcus edaphicus - has been isolated from Antarctica. (wikipedia.org)
- succinus As with all generic names in binomial nomenclature, Staphylococcus is capitalized when used alone or with a specific species. (wikipedia.org)
- Staphylococcus species can be differentiated from other aerobic and facultative anaerobic, Gram-positive cocci by several simple tests. (wikipedia.org)
- Staphylococcus species are facultative anaerobes (capable of growth both aerobically and anaerobically). (wikipedia.org)
- On Baird Parker medium, Staphylococcus species grow fermentatively, except for S. saprophyticus, which grows oxidatively. (wikipedia.org)
- Staphylococcus species are resistant to bacitracin (0.04 U disc: resistance = (wikipedia.org)
- A seventh species has also been described - Staphylococcus leei - from patients with gastritis. (wikipedia.org)
- in people and pets, also to differentiate among phylogenetically close related species such as S. delphini, S. intermedius, and S. pseudintermedius. (unibas.ch)
- As an alternative mode of treatment both bacteriophage endolysins and bacteriocins have been shown to possess antimicrobial efficacy against multiple species of bacteria including otherwise drug resistant strains. (lpmhealthcare.com)
- TThe Staphylococcus intermedius group (SIG) consists of three closely related coagulasepositive bacterial species including S. intermedius , S. pseudintermedius and S. delphini . (lpmhealthcare.com)
- Within the SIG, S. pseudintermedius represents the major pathogenic species and is involved in a wide variety of infections, mainly in dogs (it is also associated with pyoderma), but also, to a lesser degree, in other animals and humans. (lpmhealthcare.com)
- MPCs for S. pseudintermedius varied between the low-susceptible (16-128 μg/ml) and the high-susceptible strains (4-16 μg/ml) and were the most broadly distributed among the three species. (biomedcentral.com)
- Staphylococcus species can be identified phenotypically on the basis of a variety of conventional characteristics. (asmscience.org)
- pathogenic
- however, the bacteria may become pathogenic if they gain entry into the host tissue through trauma of the cutaneous barrier [ 2 , 3 ]. (intechopen.com)
- The diminished capacity of currently available antibiotics to control pathogenic bacteria is a major cause for concern. (nih.gov)
- Still Y. enterocolitica is a group of very heterogeneous bacteria, which can be divided into 6 biotypes and about 30 serotypes and into pathogenic and non-pathogenic strains. (helsinki.fi)
- infections
- Moreover, in the case of human medicine, the costs associated with the treatment of infections caused by antimicrobial-resistant bacteria represent a serious public health burden in hospital and community settings [ 10 ]. (intechopen.com)
- Pradofloxacin is indicated for the treatment of: acute infections of the upper respiratory tract caused by susceptible strains of Pasteurella multocida, Escherichia coli and the Staphylococcus intermedius group (including S. pseudintermedius). (wikipedia.org)
- wound infections and abscesses caused by susceptible strains of Pasteurella multocida and the Staphylococcus intermedius group (including S. pseudintermedius) [for oral suspension only]. (wikipedia.org)
- Ear and skin infections with the bacteria Staphylococcus pseudintermedius and the yeast Malassezia pachydermatis are common secondary to atopic dermatitis. (wikipedia.org)
- Escherichia coli , Pseudomonas aeruginosa , and Staphylococcus pseudintermedius ) and is thus indicated for treatment of canine bacterial infections, including urinary, skin, and ear infections. (biomedcentral.com)
- In this study we created a nisin derivative with enhanced antimicrobial activity against S. pseudintermedius.In addition, the novel nisin derivative exhibits an enhanced ability to impair biofilm formation and to reduce the density of established biofilms.The activities of this peptide represent a significant improvement over that of the wild-type nisin peptide and merit further investigation with a view to their use to treat S. pseudintermedius infections. (nih.gov)
- The activities of this peptide represent a significant improvement over that of the wild-type nisin peptide and merit further investigation with a view to their use to treat S. pseudintermedius infections. (nih.gov)
- Coagulase-negative staphylococci (CoNS) are an important cause of nosocomial bloodstream infections, but they are also the most common contaminants of blood cultures. (asmscience.org)
- pyoderma
- 2009). Nearly all cases of pyoderma in dogs are caused by Staphylococcus intermedius (DeBoer 2006). (scielo.org.za)
- Deep pyoderma associated with S. intermedius is possibly the most common reason for administration of antimicrobials in dogs (Guardabassi, Loeber & Jacobson 2004a). (scielo.org.za)
- strains
- However, although a relevant proportion of pets and nursing home residents was found to be carrier of MDR staphylococci, the residents had no increased risk of being carriers of these strains when living in homes with pets or having contact with these animals at least once a week. (unibas.ch)
- In evaluating the role of pets as reservoir of antibiotic resistant staphylococci, the network of contacts and their physical intensity, together with information on multi-drug resistance carriage in humans and pets should be considered for a correct estimation of the transmission and distribution of antibiotic resistant strains among different hosts. (unibas.ch)
- In this study, we compared for the first time orbifloxacin MPCs between susceptible strains of Escherichia coli , Pseudomonas aeruginosa , and Staphylococcus pseudintermedius of canine origin. (biomedcentral.com)
- antimicrobial-resistant
- The widespread and often indiscriminate use of antimicrobials in animals is considered an important driving force behind the emergence and spread of antimicrobial-resistant bacteria. (intechopen.com)
- The transfer of antimicrobial-resistant bacteria residing in, or on, animals to close human contacts or the introduction of the bacteria into the food supply chain is a cause for concern. (intechopen.com)
- resistant
- Methods: I investigated the presence of multi-drug resistant (MDR) staphylococci in cats, dogs and people in the nursing homes and in the community of four Swiss Cantons (Berne, Ticino, Vaud and Zurich). (unibas.ch)
- Developing novel assays for testing environmental effects of antibiotics residues on microbial populations in polluted river catchments (BBSRC / AstraZeneca) Estimating human exposure to antibiotic resistant bacteria in the environment (EU/ERDF). (exeter.ac.uk)
- Human recreational exposure to antibiotic resistant bacteria in coastal bathing waters. (exeter.ac.uk)
- pathogens
- Nisin is a member of the lantibiotic family of antimicrobial peptides that exhibit potent antibacterial activity against many gram-positive bacteria, including human and animal pathogens such as Staphylococcus, Bacillus, Listeria, and Clostridium. (nih.gov)
- antimicrobials
- Analysis of antimicrobial susceptibility profiles of S. intermedius isolated from canine pyodermas will guide veterinarians' use of the most appropriate agent and encourage prudent use of antimicrobials in companion animals. (scielo.org.za)
- providing the bacteria with chemical and physical protection from the host immune response and the effects of antimicrobials . (nih.gov)
- anaerobic
- As a result, pradofloxacin is active against a wide range of Gram-positive and Gram-negative bacteria including anaerobic bacteria. (wikipedia.org)
- staphylococcal
- However, Staphylococcus is not capitalized or italicized when used in adjectival forms, as in a staphylococcal infection, or as the informal plural (staphylococci). (wikipedia.org)
- The analysis of the staphylococcal population composition of healthy cats and dogs revealed that S. pseudintermedius was present in 27 % (70/256) of healthy dogs and 3 % (8/277) of healthy cats, whereas S. felis was isolated only from cats and represented 31 % of their coagulase-negative staphylococcal isolates. (unibas.ch)
- virulence
- Biofilm formation is now recognized as an important virulence factor in several Staphylococcus spp. (nih.gov)
- veterinary
- Canine skin samples submitted to a veterinary diagnostic laboratory for microbiological culture and sensitivity between January 2007 and June 2010, from which Staphylococcus intermedius was isolated, were selected for this investigation. (scielo.org.za)
- The propensity for staphylococci to develop antimicrobial resistance is a cause for great concern in both human and veterinary medicine [ 14 ]. (intechopen.com)
- biofilms
- A bioengineered nisin derivative to control biofilms of Staphylococcus pseudintermedius. (nih.gov)
- sessile
- complex, sessile communities of bacteria embedded in an organic polymer matrix . (nih.gov)
- We propose that the bacteriostatic activity of clarithromycin is accentuated when fosfoymcin is present, as it may allow better penetration into the biofilm matrix, allowing fosfomycin access to sessile bacteria near the surface of attachment. (biomedcentral.com)
- emergence
- The purpose of this mini-review is to provide a background to the genus Staphylococcus and the emergence of antimicrobial resistance as well as a discussion on the most significant antimicrobial resistance mechanisms. (intechopen.com)
- strain
- B) Growth inhibition of S. intermedius DSM 20373, S. pseudintermedius DK729 and S. pseudintermedius DSM21284 by the nisin A producing strain L. lactis NZ9800 pDF05 (pCI372-nisA) and the nisin derivative I4V producing strain L. lactis NZ9800 pDF12 (nisA-I4V). (nih.gov)
- humans
- 2005). Although S. intermedius is not usually isolated from humans owing to its host-specificity for canine corneocytes, transmission between humans and their pets has been demonstrated (Fitzgerald 2009). (scielo.org.za)
- Additionally, evidence of zoonotic transmission of S. pseudintermedius from dogs to humans has been reported ( 3 , 4 ). (cdc.gov)
- genus
- The current Linnaean classification scheme for the genus Staphylococcus . (intechopen.com)
- Staphylococcus (from the Greek: σταφυλή, staphylē, "grape" and κόκκος, kókkos, "granule") is a genus of Gram-positive bacteria. (wikipedia.org)
- bacterial
- Reversible association between pradofloxacin and DNA gyrase or DNA topoisomerase IV in the target bacteria results in inhibition of these enzymes and rapid death of the bacterial cell. (wikipedia.org)
- antibiotic resistance
- Isolated bacteria were identified and their phenotypic antibiotic resistance profile evaluated. (unibas.ch)
- conclusions
- Discussion and conclusions: MDR staphylococci were recovered in relevant proportions from healthy pets and people. (unibas.ch)
- group
- This group is the only clade within the staphylococci to possess this gene. (wikipedia.org)
- Micrococcaceae
- Ættkvíslinni Staphylococcus var áður skipað í ættina Micrococcaceae en hefur nú verið skipað í ættina Staphylococcaceae innan fylkingarinnar Firmicutes en míkrókokkarnir teljast býsna fjarskyldir (eru í fylkingunni Actinobacteria ). (wikipedia.org)
- Historically, the genera Staphylococcus and Micrococcus were placed together with the genera Stomatococcus and Planococcus in the family Micrococcaceae containing grampositive, catalase-positive cocci. (asmscience.org)
- carriage
- I could show strong physical closeness of pets with their owners in households and the high emotional importance of this relationship, but I did not observe any evident impact of pets on carriage of MDR staphylococci in their owners. (unibas.ch)
- dogs
- Between March 2008 and December 2009 I collected nasal swabs from 978 people and nasal and ear swabs from 256 dogs and 277 cats and checked them for the presence of staphylococci. (unibas.ch)
- rapid
- Results: Rapid and reliable identification of staphylococci by matrix assisted laser desorption ionisation - time of flight mass spectrometry (MALDI-TOF MS) was a pre-requisite to understand the distribution of Staphylococcus spp. (unibas.ch)
- skin
- A hot spot can manifest and spread rapidly in a matter of hours as secondary Staphylococcus infection causes the top layers of the skin to break down and as pus becomes trapped in the hair. (wikipedia.org)
- presence
- In the presence of an EPI, the MICs of P. aeruginosa mutants decreased markedly, those of E. coli mutants decreased moderately, and those of S. pseudintermedius mutants were unaffected. (biomedcentral.com)
- treat
- The bacterium is increasingly difficult to treat and K. pneumoniae is considered a reservoir of antimicrobial resistance genes, including those encoding resistance to carbapenems and colistin. (lpmhealthcare.com)
- formation
- One of the most important phenotypical features used in the classification of staphylococci is their ability to produce coagulase, an enzyme that causes blood clot formation. (wikipedia.org)
- We selected these agents, because they prevent biofilm formation and induce antimicrobial synergism that may also target other staphylococci. (biomedcentral.com)
- found
- Staphylococcus has been found to be a nectar-inhabiting microbe. (wikipedia.org)
- Regarding resistance mechanisms, only one QRDR mutation in gyrA was found in all of the 10 mutants of E. coli and in 4 of the 10 mutants of P. aeruginosa , whereas mutations in both grlA and gyrA were found in 3 mutants and one mutation in grlA was found in 2 mutants among the 10 mutants of S. pseudintermedius . (biomedcentral.com)
- reference
- Antimicrobial resistance of S. intermedius was most prevalent with reference to ampicillin followed by resistance to tetracycline and then potentiated sulphonamides. (scielo.org.za)
- study
- In this study we created a nisin derivative with enhanced antimicrobial activity against S. pseudintermedius. (nih.gov)
- activity
- This antimicrobial agent exhibits bactericidal activity against numerous Gram-negative and Gram-positive bacteria (e.g. (biomedcentral.com)