aureus
- The name S. intermedius was proposed for isolates that differed from Staphylococcus aureus in various biochemical reactions and with regard to cell wall composition (Hajek 1976). (scielo.org.za)
- Similar to S. aureus colonisation seen in humans, healthy dogs frequently carry S. intermedius as part of their normal microflora. (scielo.org.za)
- Although information regarding the pathogenic process of S. pseudintermedius is limited, the bacterium is known to possess virulence factors similar to those found in S. aureus , including a leukotoxin comparable to the Panton-Valentine leukocidase associated with community-acquired S. aureus infection ( 1 ). (cdc.gov)
- Two species were described in 2015 - Staphylococcus argenteus and Staphylococcus schweitzeri - both of which were previously considered variants of S. aureus. (wikipedia.org)
- These species belong to two separate groups - the S. aureus (S. aureus alone) group and the S. hyicus-intermedius group (the remaining five). (wikipedia.org)
- The emergence of livestock-associated methicillin-resistant Staphylococcus aureus and the description of a novel methicillin-resistant gene, mecC, have renewed concerns regarding the role of animals as reservoirs and a source for the evolution of novel, virulent zoonotic pathogens. (intechopen.com)
- Staphylococcus aureus is the most significant species within this genus by virtue of its versatility as a pathogen in humans and animals [ 4 , 5 ]. (intechopen.com)
- International Journal of Medical Microbiology Available online 3 May 2017 Methicillin-resistant Staphylococcus aureus Screening PCR adapted to locally emerging variants-Evaluation of novel SCCmec primers. (pearltrees.com)
- University of Denmark - MAI 2012 - Zinc resistance of Staphylococcus aureus of animal origin is strongly associated with methici. (pearltrees.com)
- The bacteria tracked by the researchers was methicillin-resistant Staphylococcus aureus, or MRSA, and is also known as multidrug-resistant Staphylococcus aureus as it has developed resistance to beta-lactam antibiotics. (pearltrees.com)
- Staphylococcus aureus infections of the skin and soft tissue pose a major concern to public health, largely owing to the steadily increasing prevalence of drug resistant isolates. (lpmhealthcare.com)
- Recently we have used bioengineering strategies to enhance the activity of nisin against several high profile targets, including multi-drug resistant clinical pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) and also against staphylococci and streptococci associated with bovine mastitis. (nih.gov)
- Það var Sir Alexander Ogston , skoskur læknir og prófessor við Háskólann í Aberdeen , sem fyrstur lýsti tegundinni sem í dag kallast Staphylococcus aureus og sýndi fram á að hún getur valdið sýkingum í mönnum árið 1880 . (wikipedia.org)
methicillin-resistant Staphylococcus pseudintermedius
- FRONTIERS IN MICROBIOLOGY 18/10/16 Systematic Review on Global Epidemiology of Methicillin-Resistant Staphylococcus pseudintermedius: Inference of Population Structure from Multilocus Sequence Typing Data. (pearltrees.com)
- However, newly emerging pathogens such as methicillin resistant Staphylococcus pseudintermedius (MRSP) pose a significant threat in terms of veterinary health and as a reservoir for antibiotic resistance determinants. (nih.gov)
- Against this backdrop, methicillin-resistant Staphylococcus pseudintermedius (MRSP) has emerged over the last decade as a critically important, opportunistic canine pathogen responsible for skin, soft tissue, and surgical site infections . (nih.gov)
- In this study, we treated bacterial biofilms produced by methicillin-resistant Staphylococcus pseudintermedius (MRSP) with a combination of fosfomycin and clarithromycin. (biomedcentral.com)
MRSP
- Of concern is the emergence and widespread international recognition of methicillin-resistant S. pseudintermedius (MRSP) ( 1 ). (cdc.gov)
- The potential for zoonotic transmission and concerns that MRSP could be mistaken for other methicillin-resistant staphylococci ( 1 , 2 ) suggest the need for further investigation into the epidemiology of this pathogen. (cdc.gov)
- The study also confirmed the emergence of meticillin-resistant Staphylococcus pseudintermedius (MRSP), a multidrug-resistant small animal pathogen with similarities to MRSA. (rvc.ac.uk)
- Beever L, Bond R, Graham PA, Jackson B, Lloyd DH, Loeffler A. Increasing antimicrobial resistance in clinical isolates of Staphylococcus intermedius group bacteria and emergence of MRSP in the UK . (rvc.ac.uk)
- At the end of my study I also analysed the clinical implications of methicillin-resistant S. pseudintermedius (MRSP) infections using as an example the isolation of this microorganism from a pyoderma lesion in a dog that underwent various antibiotic treatments before the correct diagnosis was made and an appropriate antibiotic treatment was administered. (unibas.ch)
coagulase-positive
- The Staphylococcus intermedius Group includes S. intermedius, S. pseudintermedius and S. delphini, coagulase-positive bacteria commonly isolated from animals. (supsi.ch)
- Staphylococcus pseudintermedius is a coagulase-positive species in the S. intermedius group. (cdc.gov)
- Coagulase-positive Staphylococcus spp. (intechopen.com)
isolates
- Researchers from the Queen Mother Hospital for Animals studying Staphylococcus pseudintermedius , the predominant dog skin pathogen, showed for the first time that resistance is increasing to the most clinically relevant antimicrobials.Results from a large longitudinal retrospective survey including over 14,500 bacterial isolates from two UK laboratories showed a trend of increasing resistance over the 10-year period. (rvc.ac.uk)
- The analysis of the staphylococcal population composition of healthy cats and dogs revealed that S. pseudintermedius was present in 27 % (70/256) of healthy dogs and 3 % (8/277) of healthy cats, whereas S. felis was isolated only from cats and represented 31 % of their coagulase-negative staphylococcal isolates. (unibas.ch)
pyoderma
- Canine deep pyoderma (CDP) is a difficult to treat skin disease in small animals1 characterized by dissemination of bacteria into the deep dermis and/or bacterial infection of the panniculus. (pharmiweb.com)
- Bacteria in lesions of deep pyoderma are often located in the center of fibrotic or inflammatory foci, associated with chronic diseases and scarring. (pharmiweb.com)
- 2009). Nearly all cases of pyoderma in dogs are caused by Staphylococcus intermedius (DeBoer 2006). (scielo.org.za)
- Deep pyoderma associated with S. intermedius is possibly the most common reason for administration of antimicrobials in dogs (Guardabassi, Loeber & Jacobson 2004a). (scielo.org.za)
- Within the SIG, S. pseudintermedius represents the major pathogenic species and is involved in a wide variety of infections, mainly in dogs (it is also associated with pyoderma), but also, to a lesser degree, in other animals and humans. (lpmhealthcare.com)
pathogenic
- however, the bacteria may become pathogenic if they gain entry into the host tissue through trauma of the cutaneous barrier [ 2 , 3 ]. (intechopen.com)
- The diminished capacity of currently available antibiotics to control pathogenic bacteria is a major cause for concern. (nih.gov)
delphini
- 69 strains of different biological and geographic origins, identified by partial hsp60 gene sequencing as S. intermedius (n=15), S. pseudintermedius (n=32) and S. delphini (n=22), were analyzed by MALDI-TOF MS. The estimated sensitivity, specificity and efficiency were calculated. (supsi.ch)
- The Cohen's kappa coefficient indicated almost perfect agreement between MALDI-TOF MS and hsp60 gene sequencing for the identification of S. intermedius [0.96 (95% CI: 0.87-1.04)], and substantial agreement for S. delphini and S. pseudintermedius [0.70 (95% CI: 0.52-0.89) and 0.76 (95% CI: 0.616-0.92), respectively]. (supsi.ch)
- The overall efficiency of the proteomic identification ranged between 0.88 (95% CI: 0.78-0.95) for S. pseudintermedius and S. delphini and 0.99 (95% CI: 0.92-0.99) for S. intermedius. (supsi.ch)
- in people and pets, also to differentiate among phylogenetically close related species such as S. delphini, S. intermedius, and S. pseudintermedius. (unibas.ch)
- A first MLST scheme based on five loci was initially proposed in 2007 to provide insight into the overall population genetic structure of the Staphylococcus intermedius Group (SIG), which includes S. intermedius and S. delphini in addition to S. pseudintermedius (Bannoehr et al. (pearltrees.com)
- TThe Staphylococcus intermedius group (SIG) consists of three closely related coagulasepositive bacterial species including S. intermedius , S. pseudintermedius and S. delphini . (lpmhealthcare.com)
clinical
- For the secondary endpoints, the Phovia treated group showed a statistically significant reduction of clinical scores, and an improvement in neutrophil engulfing bacteria scores. (pharmiweb.com)
- Due to the ubiquity of many of the species within this group, their clinical significance has traditionally been dismissed, and when isolated from clinical specimens, the bacteria have merely been regarded as contaminants [ 12 ]. (intechopen.com)
- Clinical efficacy was established in skin and soft tissue infections (wounds and abscesses) in the dog and cat, and urinary tract infections (cystitis) in the dog, associated with bacteria susceptible to orbifloxacin. (drugs.com)
infections
- Previously misidentified as S. intermedius , S. pseudintermedius is now recognized as a leading cause of opportunistic infection in dogs ( 1 ) and a cause of sporadic infections in other species, including humans ( 1 , 2 ). (cdc.gov)
- Pradofloxacin is indicated for the treatment of: acute infections of the upper respiratory tract caused by susceptible strains of Pasteurella multocida, Escherichia coli and the Staphylococcus intermedius group (including S. pseudintermedius). (wikipedia.org)
- wound infections and abscesses caused by susceptible strains of Pasteurella multocida and the Staphylococcus intermedius group (including S. pseudintermedius) [for oral suspension only]. (wikipedia.org)
- Other Staphylococcus species, collectively termed coagulase-negative staphylococci (CNS), are responsible for a variety of opportunistic infections in humans and animals [ 11 ]. (intechopen.com)
- Moreover, in the case of human medicine, the costs associated with the treatment of infections caused by antimicrobial-resistant bacteria represent a serious public health burden in hospital and community settings [ 10 ]. (intechopen.com)
- Introduction Staphylococcus pseudintermedius is a bacterial commensal of the skin and mucosae of dogs and also the most prevalent cause of canine bacterial infections (Bannoehr and Guardabassi, 2012). (pearltrees.com)
- Ear and skin infections with the bacteria Staphylococcus pseudintermedius and the yeast Malassezia pachydermatis are common secondary to atopic dermatitis. (wikipedia.org)
- Escherichia coli , Pseudomonas aeruginosa , and Staphylococcus pseudintermedius ) and is thus indicated for treatment of canine bacterial infections, including urinary, skin, and ear infections. (biomedcentral.com)
- In this study we created a nisin derivative with enhanced antimicrobial activity against S. pseudintermedius.In addition, the novel nisin derivative exhibits an enhanced ability to impair biofilm formation and to reduce the density of established biofilms.The activities of this peptide represent a significant improvement over that of the wild-type nisin peptide and merit further investigation with a view to their use to treat S. pseudintermedius infections. (nih.gov)
- The activities of this peptide represent a significant improvement over that of the wild-type nisin peptide and merit further investigation with a view to their use to treat S. pseudintermedius infections. (nih.gov)
pathogens
- Nisin is a member of the lantibiotic family of antimicrobial peptides that exhibit potent antibacterial activity against many gram-positive bacteria, including human and animal pathogens such as Staphylococcus, Bacillus, Listeria, and Clostridium. (nih.gov)
- Common bacterial pathogens associated with the perpetuation of canine OE include Staphylococcus spp , Streptococcus , Pseudomonas, Proteus and Escherichia coli , with Staphylococcus pseudintermedius being the most frequent. (bmj.com)
bacterial
- Reversible association between pradofloxacin and DNA gyrase or DNA topoisomerase IV in the target bacteria results in inhibition of these enzymes and rapid death of the bacterial cell. (wikipedia.org)
species
- Staphylococcus species are facultatively anaerobic, Gram-positive, coccal bacteria that belong to the family Micrococcaceae (Rich 2005). (scielo.org.za)
- The Staphylococcus genus includes at least 40 species. (wikipedia.org)
- A new coagulase negative species - Staphylococcus edaphicus - has been isolated from Antarctica. (wikipedia.org)
- succinus As with all generic names in binomial nomenclature, Staphylococcus is capitalized when used alone or with a specific species. (wikipedia.org)
- Staphylococcus species can be differentiated from other aerobic and facultative anaerobic, Gram-positive cocci by several simple tests. (wikipedia.org)
- Staphylococcus species are facultative anaerobes (capable of growth both aerobically and anaerobically). (wikipedia.org)
- On Baird Parker medium, Staphylococcus species grow fermentatively, except for S. saprophyticus, which grows oxidatively. (wikipedia.org)
- Staphylococcus species are resistant to bacitracin (0.04 U disc: resistance = (wikipedia.org)
- A seventh species has also been described - Staphylococcus leei - from patients with gastritis. (wikipedia.org)
- Staphylococci are natural residents on the skin and mucous membranes of a wide range of host species [ 1 ]. (intechopen.com)
- As an alternative mode of treatment both bacteriophage endolysins and bacteriocins have been shown to possess antimicrobial efficacy against multiple species of bacteria including otherwise drug resistant strains. (lpmhealthcare.com)
- MPCs for S. pseudintermedius varied between the low-susceptible (16-128 μg/ml) and the high-susceptible strains (4-16 μg/ml) and were the most broadly distributed among the three species. (biomedcentral.com)
resistant
- A critical part of the results includes reducing the duration of systemic antibiotic use, as it is becoming abundantly clear in the international community that long-term antibiotic use has a high risk factor for the development of antibiotic resistant bacteria. (pharmiweb.com)
- The widespread and often indiscriminate use of antimicrobials in animals is considered an important driving force behind the emergence and spread of antimicrobial-resistant bacteria. (intechopen.com)
- The transfer of antimicrobial-resistant bacteria residing in, or on, animals to close human contacts or the introduction of the bacteria into the food supply chain is a cause for concern. (intechopen.com)
- Methods: I investigated the presence of multi-drug resistant (MDR) staphylococci in cats, dogs and people in the nursing homes and in the community of four Swiss Cantons (Berne, Ticino, Vaud and Zurich). (unibas.ch)
- In evaluating the role of pets as reservoir of antibiotic resistant staphylococci, the network of contacts and their physical intensity, together with information on multi-drug resistance carriage in humans and pets should be considered for a correct estimation of the transmission and distribution of antibiotic resistant strains among different hosts. (unibas.ch)
- Researchers discover link between use of antibiotics and MRSA [Date: 2012-09-Researchers tracking a penicillin-type resistant bacterium that leads to infection in some hospital patients have discovered that occurrence falls significantly when prescriptions of a common antibiotic of the fluoroquinolone family also fall. (pearltrees.com)
- Developing novel assays for testing environmental effects of antibiotics residues on microbial populations in polluted river catchments (BBSRC / AstraZeneca) Estimating human exposure to antibiotic resistant bacteria in the environment (EU/ERDF). (exeter.ac.uk)
- Human recreational exposure to antibiotic resistant bacteria in coastal bathing waters. (exeter.ac.uk)
emergence
- The purpose of this mini-review is to provide a background to the genus Staphylococcus and the emergence of antimicrobial resistance as well as a discussion on the most significant antimicrobial resistance mechanisms. (intechopen.com)
Pseudomonas
- In this study, we compared for the first time orbifloxacin MPCs between susceptible strains of Escherichia coli , Pseudomonas aeruginosa , and Staphylococcus pseudintermedius of canine origin. (biomedcentral.com)
strains
- However, although a relevant proportion of pets and nursing home residents was found to be carrier of MDR staphylococci, the residents had no increased risk of being carriers of these strains when living in homes with pets or having contact with these animals at least once a week. (unibas.ch)
antimicrobial resistance
- Antimicrobial resistance of S. intermedius was most prevalent with reference to ampicillin followed by resistance to tetracycline and then potentiated sulphonamides. (scielo.org.za)
- The propensity for staphylococci to develop antimicrobial resistance is a cause for great concern in both human and veterinary medicine [ 14 ]. (intechopen.com)
- The bacterium is increasingly difficult to treat and K. pneumoniae is considered a reservoir of antimicrobial resistance genes, including those encoding resistance to carbapenems and colistin. (lpmhealthcare.com)
antibiotic
- Isolated bacteria were identified and their phenotypic antibiotic resistance profile evaluated. (unibas.ch)
Microbiology
- Identification of Staphylococcus intermedius Group by MALDI-TOF MS. Systematic and Applied Microbiology , 34 (1). (supsi.ch)
canine
- Canine skin samples submitted to a veterinary diagnostic laboratory for microbiological culture and sensitivity between January 2007 and June 2010, from which Staphylococcus intermedius was isolated, were selected for this investigation. (scielo.org.za)
- Analysis of antimicrobial susceptibility profiles of S. intermedius isolated from canine pyodermas will guide veterinarians' use of the most appropriate agent and encourage prudent use of antimicrobials in companion animals. (scielo.org.za)
- 2005). Although S. intermedius is not usually isolated from humans owing to its host-specificity for canine corneocytes, transmission between humans and their pets has been demonstrated (Fitzgerald 2009). (scielo.org.za)
antimicrobials
- providing the bacteria with chemical and physical protection from the host immune response and the effects of antimicrobials . (nih.gov)
anaerobic
- As a result, pradofloxacin is active against a wide range of Gram-positive and Gram-negative bacteria including anaerobic bacteria. (wikipedia.org)
virulence
- Biofilm formation is now recognized as an important virulence factor in several Staphylococcus spp. (nih.gov)
biofilms
- A bioengineered nisin derivative to control biofilms of Staphylococcus pseudintermedius. (nih.gov)
sessile
- complex, sessile communities of bacteria embedded in an organic polymer matrix . (nih.gov)
- We propose that the bacteriostatic activity of clarithromycin is accentuated when fosfoymcin is present, as it may allow better penetration into the biofilm matrix, allowing fosfomycin access to sessile bacteria near the surface of attachment. (biomedcentral.com)
Group
- Identification of Staphylococcus intermedius Group by MALDI-TOF MS. (supsi.ch)
- MALDI-TOF MS is thus a valuable and reliable tool for the rapid and accurate identification of bacteria belonging to the S. intermedius Group. (supsi.ch)
- This group is the only clade within the staphylococci to possess this gene. (wikipedia.org)
strain
- B) Growth inhibition of S. intermedius DSM 20373, S. pseudintermedius DK729 and S. pseudintermedius DSM21284 by the nisin A producing strain L. lactis NZ9800 pDF05 (pCI372-nisA) and the nisin derivative I4V producing strain L. lactis NZ9800 pDF12 (nisA-I4V). (nih.gov)
orbifloxacin
- ORBAX ® (orbifloxacin) Tablets are indicated for the management of diseases in dogs and cats associated with bacteria susceptible to orbifloxacin. (drugs.com)
zoonotic
- Additionally, evidence of zoonotic transmission of S. pseudintermedius from dogs to humans has been reported ( 3 , 4 ). (cdc.gov)
genus
- Staphylococcus (from the Greek: σταφυλή, staphylē, "grape" and κόκκος, kókkos, "granule") is a genus of Gram-positive bacteria. (wikipedia.org)
- The current Linnaean classification scheme for the genus Staphylococcus . (intechopen.com)
conclusions
- Discussion and conclusions: MDR staphylococci were recovered in relevant proportions from healthy pets and people. (unibas.ch)
infection
- However, Staphylococcus is not capitalized or italicized when used in adjectival forms, as in a staphylococcal infection, or as the informal plural (staphylococci). (wikipedia.org)
- A hot spot can manifest and spread rapidly in a matter of hours as secondary Staphylococcus infection causes the top layers of the skin to break down and as pus becomes trapped in the hair. (wikipedia.org)
resistance
- 1996) that had indicated a stable, predictable resistance pattern for S. pseudintermedius from dogs during the 1980s and 1990s. (rvc.ac.uk)
- Regarding resistance mechanisms, only one QRDR mutation in gyrA was found in all of the 10 mutants of E. coli and in 4 of the 10 mutants of P. aeruginosa , whereas mutations in both grlA and gyrA were found in 3 mutants and one mutation in grlA was found in 2 mutants among the 10 mutants of S. pseudintermedius . (biomedcentral.com)
Micrococcaceae
- Ættkvíslinni Staphylococcus var áður skipað í ættina Micrococcaceae en hefur nú verið skipað í ættina Staphylococcaceae innan fylkingarinnar Firmicutes en míkrókokkarnir teljast býsna fjarskyldir (eru í fylkingunni Actinobacteria ). (wikipedia.org)
dogs
- Between March 2008 and December 2009 I collected nasal swabs from 978 people and nasal and ear swabs from 256 dogs and 277 cats and checked them for the presence of staphylococci. (unibas.ch)
results
- Results: Rapid and reliable identification of staphylococci by matrix assisted laser desorption ionisation - time of flight mass spectrometry (MALDI-TOF MS) was a pre-requisite to understand the distribution of Staphylococcus spp. (unibas.ch)
cases
- The causative organism is Staphylococcus pseudintermedius (formerly S. intermedius ) in the vast majority of cases. (pharmiweb.com)
important
- One of the most important phenotypical features used in the classification of staphylococci is their ability to produce coagulase, an enzyme that causes blood clot formation. (wikipedia.org)
study
- In this study we created a nisin derivative with enhanced antimicrobial activity against S. pseudintermedius. (nih.gov)