Caseous LymphadenitisInfectionDiphtheriaeFormation of abscessesBacterialAntibioticsDryland distemperPathogensPathogenicLymph nodesCausativeLesionsUlcerative lymphangitisStaphylococcusSpeciesStreptococcusFeverGoatsOrganismToxinAspirationDrainageUltrasoundPredominantContaminateSurgicallyCorynebacteriaInfectionsHorses developInfectiousVirulenceInfectHorse'sGramVitroStrainsOrgansOccurFormChestBiochemicalDiseaseDevelopInternalClinicalSmallCasesInvestigationFluidSpreadMultipleFlies
Caseous Lymphadenitis7
- Caseous lymphadenitis (CLA) is an infectious disease caused by the bacterium Corynebacterium pseudotuberculosis, that affects the lymphatic system, resulting in abscesses in the lymph nodes and internal organs. (wikipedia.org)
- The causative organism of caseous lymphadenitis is Corynebacterium pseudotuberculosis. (wikipedia.org)
- Caseous lymphadenitis (CL) is a chronic, contagious bacterial disease that manifests clinically as abscesses of peripheral and/or internal lymph nodes and organs. (msdvetmanual.com)
- Caseous lymphadenitis (CL) is a chronic, contagious disease caused by the bacterium Corynebacterium pseudotuberculosis . (msdvetmanual.com)
- Corynebacterium ulcerans may cause diphtheria in humans and caseous lymphadenitis in animals. (cdc.gov)
- Moreover, C. ulcerans and C. pseudotuberculosis may produce phospholipase D, the major virulence factor involved in caseous lymphadenitis, which is a disease that mainly affects sheep, goats, and horses ( 3 ). (cdc.gov)
- Hence, we sought to implement a combined approach for characterizing the entire exoproteome of the pathogenic bacterium Corynebacterium pseudotuberculosis , the etiological agent of caseous lymphadenitis (CLA) in sheep and goats. (biomedcentral.com)
Infection10
- The infection can spread through the blood or lymphatic system, causing abscesses to form in other lymph nodes or internal organs throughout the body. (wikipedia.org)
- Once found mainly in California, this bacterial infection has now been documented in 25 states across the country. (equusmagazine.com)
- The infection, which usually causes abscesses in the chest or elsewhere in the horse's body, was first reported in horses in San Mateo County (San Francisco Bay Area) of California in 1915. (equusmagazine.com)
- The incubation period-the time between the initial infection and the formation of the abscess-is about three to four weeks. (equusmagazine.com)
- Infection most commonly leads to external abscesses, though some horses develop more serious forms including internal abscesses and ulcerative lymphangitis (infection of the limb). (equishopper.com)
- Pigeon Fever is the common term for an infection caused by the bacterial organism Corynebacterium pseudotuberculosis (also referred to as Dryland Distemper). (eliteequineks.com)
- and urinary tract infections and mastitis (affecting milk production) in cattle due to infection with Corynebacterium renale , Corynebacterium cystidis , Corynebacterium pilosum , and Corynebacterium bovis . (medscape.com)
- These opportunistic anaerobic bacteria may also cause bed sores, pressure sores, aspiration pneumonia, chronic otitis media (ear infection), chronic sinusitis, and osteomyelitis (bone infection). (microgeninc.com)
- In goat kids it may be Navel infection arthritis caused by corynebacterium pyogensis, streptoceoci, staphylococci, while non-superative arthritis is by birth, caused due to deficiency of vitamins and minerals. (health-articles.net)
- Pyomyositis is a bacterial infection of the skeletal muscles which results in an abscess . (mdwiki.org)
Diphtheriae5
- The Corynebacterium species C. diphtheriae , C. ulcerans , and C. pseudotuberculosis form the C. diphtheriae group, as shown by 16S rRNA gene sequence analysis ( 1 ). (cdc.gov)
- The genus contains the species Corynebacterium diphtheriae and the nondiphtherial corynebacteria, collectively referred to as diphtheroids. (medscape.com)
- In some endemic locations, such as India, 44% of throat and nasal swabs tested positive for C diphtheriae and Corynebacterium pseudodiphtheriticum . (medscape.com)
- Corynebacterium pseudotuberculosis is a facultative intracellular pathogen that belongs to the so-called CMN ( Corynebacterium-Mycobacterium-Nocardia ) group, a distinct subgroup of the Actinobacteria that also includes other highly important bacterial pathogens, such as Corynebacterium diphtheriae and Mycobacterium tuberculosis . (biomedcentral.com)
- From the nasopharynx of a 5-year-old child it was excreted amicroorganism which is identical to Corynebacterium diphtheriae dose according to morphological and biochemical signs.Microorganism does not produce exotoxin. (eneutron.info)
Formation of abscesses2
- Typical manifestations of CLA in small ruminants include formation of abscesses in superficial and internal lymph nodes, and in visceral organs [ 3 ]. (biomedcentral.com)
- However, incidence of pulmonary suppuration and formation of abscesses increases with the age. (cswri.res.in)
Bacterial7
- Some horses have developed lung abscesses after inhaling a concentration of bacterial organisms. (eliteequineks.com)
- Corynebacterium pseudotuberculosis has been cultured from some cases (particularly of ulcerative lymphangitis, but in others, a bacterial culture is negative. (wikipedia.org)
- In fact, one might expect that the majority of the virulence determinants of C. pseudotuberculosis would be present in the exoproteome, i.e . the entire set of bacterial proteins found in the extracellular milieu [ 7 ]. (biomedcentral.com)
- Among animals with bacterial isolation, Staphylococcus aureus (6/34 = 17.6%), Escherichia coli (5/34 = 14.7%), Staphylococcus beta-hemolytic (5/34 = 14.7%), and Trueperella pyogenes (3/34 = 8.8%) were predominant, in addition to a miscellaneous of other bacteria isolated in minor frequency, e.g. (bvsalud.org)
- In general the agents implicated in etiology of respiratory syndrome include a wide spectra of viruses such as PI 3, Adeno and Reo viruses, bacterial species such as Hemophilus, Bordetella, Pasteurella, Corynebacterium, Mycoplasma and Chlamydia along with a chain of predisposing factors mainly the environmental and managemental fluctuations. (cswri.res.in)
- Axial T1 weighted fat suppressed post IV gadolinium contrast enhanced MRI image showing a mutliloculated bacterial abscess in the left gluteal muscle which grew Staphylococcus aureus (methicillin sensitive) thought to be due to tropical pyomyositis. (mdwiki.org)
- Coronal fat suppressed post contrast image showing a multiloculated bacterial abscess in the left gluteus minimus muscle due to tropical pyomyositis. (mdwiki.org)
Antibiotics4
- Despite the fact that C. pseudotuberculosis is sensitive in vitro to almost all antibiotics that have been tested, antibiotic therapy is not very efficient. (wikipedia.org)
- Many clinicians believe that antibiotics will delay the maturation of developing abscesses and might facilitate internal abscessation. (eliteequineks.com)
- [3] However, intracellular organisms such as Corynebacterium pseudotuberculosis will be susceptible to certain antibiotics in vitro that are not effective for the specific organism in the horse. (wikipedia.org)
- These bacteria also have natural resistance to many antibiotics. (microgeninc.com)
Dryland distemper1
- Also called dryland distemper or Colorado strangles, pigeon fever develops when Corynebacterium pseudotuberculosis bacteria enter a horse's body, probably via insect bites or breaks in the skin. (equusmagazine.com)
Pathogens1
- Once a horse becomes infected with C. pseudotuberculosis, the bacteria release a toxin that ultimately spurs the body to build a thick-walled abscess around the pathogens. (equusmagazine.com)
Pathogenic2
- This article provides an overview of the most important human pathogenic bacteria. (amboss.com)
- The following table provides an overview of the nomenclature of important human pathogenic bacteria, according to their form and Gram staining properties. (amboss.com)
Lymph nodes3
- Treatment of affected animals consists of the drainage of abscesses, followed by cleansing and chemical cauterization, usually with 10% iodine, or even removal of the affected superficial lymph nodes. (wikipedia.org)
- Whereas the peripheral form presents as abscesses of single or multiple peripheral palpable lymph nodes, internal CL typically manifests as chronic weight loss and ill thrift. (msdvetmanual.com)
- The disease is characterized by abscess formation in or near major peripheral lymph nodes (external form) or within internal organs and lymph nodes (internal form). (msdvetmanual.com)
Causative2
- Pigeon fever Houseflies, stable flies, and horn flies can spread the bacterium Corynebacterium pseudotuberculosis, the causative agent of pigeon fever. (equishopper.com)
- This bacterium infects the airway, and is closely related to the causative agent of whooping cough, Bordetella pertussis. (microgeninc.com)
Lesions3
- Culture of active lesions for Corynebacterium pseudotuberculosis is diagnostically definitive. (msdvetmanual.com)
- Once established on a farm or region (endemic), it is primarily maintained by contamination of the environment with active draining lesions, animals with the internal form of the disease that contaminate the environment through nasal discharge or coughing, the ability of the bacteria to survive harsh environmental conditions, and lack of strict biosecurity necessary to reduce the number and prevent introduction of new cases. (msdvetmanual.com)
- Strains of C. ulcerans were isolated during routine bacteriological investigations in conjunction with necropsies of wild animals that were found dead or that had suspicious lesions during 1997-2013. (cdc.gov)
Ulcerative lymphangitis1
- In ulcerative lymphangitis, intravenous iodine salts may also be used, and abscesses should be poulticed or lanced. (wikipedia.org)
Staphylococcus2
- Well-recognized and common causes of community-acquired pneumonia (CAP) in adults include bacteria such as Streptococcus pneumoniae, Haemophilus influenzae , and Staphylococcus aureus , and viruses such as influenza virus, respiratory syncytial virus, human metapneumovirus, and parainfluenza virus. (biomedcentral.com)
- Pyomyositis is most often caused by the bacterium Staphylococcus aureus . (mdwiki.org)
Species3
- C. ulcerans is a zoonotic pathogen and has been found in various animal species that have contact with humans ( 5 ). (cdc.gov)
- C. ulcerans is most closely related to C. pseudotuberculosis , and distinction between these species is often difficult when using standard bacteriological methods ( 5 ). (cdc.gov)
- Ruminants-such as sheep, goats, and cattle-can also become infected with these bacteria, although cross-species transmission is rare and usually only occurs between horses and cattle because they can carry the same strain. (eliteequineks.com)
Streptococcus1
- The other bacteria identified were Proteus and Streptococcus sp. (cswri.res.in)
Fever5
- For much of the 20th century, pigeon fever was most commonly found in the Southwest and in California. (equusmagazine.com)
- It takes longer for horses with internal abscesses to show signs of disease, and those that appear tend to be fairly nonspecific, such as lethargy, decreased appetite, fever, colic, coughing and/or weight loss. (equusmagazine.com)
- Pigeon fever cases used to be found primarily in California, although within the last several years veterinarians have diagnosed cases in many areas of the western United States. (eliteequineks.com)
- Hot, dry weather is the most common environment where the organism is found, and most pigeon fever cases appear in late summer/early fall (the author first diagnosed a case in August, and her number of cases has increased exponentially since that time). (eliteequineks.com)
- Treating pigeon fever consists mainly of surgically opening the abscesses to allow drainage. (eliteequineks.com)
Goats3
- It is found mostly in goats and sheep and at the moment it has no cure. (wikipedia.org)
- During 1985-88, in sheep and goats, 7.01% of the animals were found positive for BTV antibodies on AGPT. (cswri.res.in)
- The management system also found to affect the sero-prevalence of BTD and it was higher in migratory flocks (63.29% in sheep to 84.84% in goats) compared to stationary flocks (35.03% in sheep to 72.88% in goats). (cswri.res.in)
Organism1
- c) The organism is not a bacterium, but a fungus , so is very difficult to culture. (wikipedia.org)
Toxin2
- When DNA of the phage integrates into the host bacteria's genetic material, the bacteria develop the capacity to produce this polypeptide toxin. (medscape.com)
- Consumption of foods contaminated with B. cereus may result in disease either by the consumption of pre-formed toxin or by toxins produced by these bacteria in during growth the gut. (microgeninc.com)
Aspiration1
- The authors of the present study have previously hypothesized that unrecognized aspiration of less virulent bacteria that normally inhabit the nasopharynx might also cause pneumonia, especially in persons whose upper airways are bypassed or whose ability to clear aspirated organisms is damaged [ 5 ]. (biomedcentral.com)
Drainage2
- Affected horses should be isolated because drainage from their abscesses contains a high amount of bacteria that will contaminate the environment. (eliteequineks.com)
- Ideally, an abscess should only be lanced after it has matured well and has an obvious soft spot, or the procedure should be guided with ultrasound to find the best site for drainage that avoids important structures. (wikipedia.org)
Ultrasound2
- Ultrasound may be needed to locate abscesses, assess their size and determine their maturity. (equusmagazine.com)
- Your veterinarian can also ultrasound the abscesses and find the best place to drain them. (eliteequineks.com)
Predominant2
- When identified as the predominant isolate in sputum from a patient with CAP, Corynebacterium spp. (biomedcentral.com)
- The present study examined the possibilities that: (i) careful examination of Gram-stained sputum and culture plates may reveal a predominant bacterium such as Corynebacterium spp. (biomedcentral.com)
Contaminate1
- The spores of B. cereus bacteria commonly contaminate raw foods and food materials, particularly foods that have been in contact with soil. (microgeninc.com)
Surgically1
- The abscesses within the muscle must be drained surgically (not all patient require surgery if there is no abscess). (mdwiki.org)
Corynebacteria1
Infections2
- Some develop more severe infections where they acquire multiple abscesses and become systemically ill (inappetent, febrile, and lethargic). (eliteequineks.com)
- certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)
Horses develop1
- If the horses develop internal abscesses, their disease is more serious and carries a guarded prognosis. (eliteequineks.com)
Infectious1
- The goat suffers with various disease, which are caused by bacteria, viruses, parasites and other non- infectious agents. (health-articles.net)
Virulence1
- Comparative analyses of the exoproteomes of two C. pseudotuberculosis strains, in addition to comparison with other experimentally determined corynebacterial exoproteomes, were helpful to gain novel insights into the contribution of the exported proteins in the virulence of this bacterium. (biomedcentral.com)
Infect1
- Internal abscesses can develop when the bacteria are carried into the body and infect the liver, kidney, lungs or other internal organs. (equusmagazine.com)
Horse's2
- The swellings can, however, appear anywhere on the body, especially if the bacteria entered the horse's body through a cut or abrasions. (equusmagazine.com)
- It was named because the abscesses cause swelling and give the horse's chest a "pigeon-breast" appearance. (eliteequineks.com)
Gram1
- were major Gram negative and positive bacteria, respectively. (cswri.res.in)
Vitro1
- The biotype of Corynebacterium pseudotuberculosis affecting horses and cattle is distinguishable from the biotype that infects small ruminants based on its ability to reduce nitrate in vitro. (wikipedia.org)
Strains2
- 44 proteins were commonly identified in two different strains, isolated from distinct hosts, then composing a core C. pseudotuberculosis exoproteome. (biomedcentral.com)
- Also, multidrug resistance to ≥ 3 classes of antimicrobials was found in 23.5% (8/34) strains. (bvsalud.org)
Organs1
- Abscesses can also develop on internal organs. (wikipedia.org)
Occur1
- CT scan can confirm the diagnosis before abscesses occur with enlargement of the involved muscles and hypodensity when abscess is present, terogenous attenuation and fluid collection with rim enhancement can be found. (mdwiki.org)
Form2
- Abscesses form within lymph channels, causing marked swelling of a leg with abscesses that open along a chain or progress into cellulitis. (equusmagazine.com)
- C. pseudotuberculosis bacteria tend to localize and form abscesses in the pectoral region and ventral abdomen of the horse. (eliteequineks.com)
Chest2
- According to one large study Spier and colleagues published of 538 cases, 91 percent of the horses had external abscesses, and nearly 60 percent of the abscesses were in the chest. (equusmagazine.com)
- An affected animal might be sore at the walk, usually after swelling and abscess of his chest and abdomen have occurred. (eliteequineks.com)
Biochemical1
Disease2
- The disease is also easily spread through the materials that are used during the operation of the animals such as castration, identification with ear tags or by tattooing, and dehydration of abscesses. (wikipedia.org)
- From a public health perspective, diphtheria is the most critical human disease attributed to coryneform bacteria ( 3 ). (cdc.gov)
Develop3
- An abscess can develop either at the location where the bacteria enters the body or at a nearby lymph node. (wikipedia.org)
- External abscesses develop just under the skin or within the muscles near the surface of the body. (equusmagazine.com)
- A small percentage of horses can develop internal abscesses, which are more serious. (eliteequineks.com)
Internal1
- But the internal abscesses are more difficult to identify and treat, and so these cases accounted for 40 percent of all fatalities. (equusmagazine.com)
Clinical1
- This bacterium is of relatively low clinical significance, but is used frequently to test water filters due to its very small size. (microgeninc.com)
Small1
- Although prevalence of CL varies by region and country, it is found worldwide and is of major concern for small ruminant producers in North America. (msdvetmanual.com)
Cases1
- This report present 3 cases of CAP in which Corynebacterium spp. (biomedcentral.com)
Investigation1
- Defect with dysfunction of antigen-presentation to the immunocompetent cells was found during investigation on the molecule level. (eneutron.info)
Fluid1
- CT exam showing a multiloculated fluid collection in the left gluteus minimus muscle found to be a staph aureus pyomyositis in a 12-year-old healthy boy. (mdwiki.org)
Spread1
- Flies are a major vector and can spread the bacteria, so spray affected and unaffected horses (especially ones with open wounds) with fly repellent if it is still fly season. (eliteequineks.com)
Multiple1
Flies2
- Flies can travel miles to find your horse. (equishopper.com)
- This is a site for proliferation of bacteria and the smell attracts blow flies leading to irritation and suffering. (angoras.co.za)