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  • receptor
  • According to Japanese and Russian researchers' data, the patients suffering from larynx cancer and some other malignant growths, even before treatment starts experience increase of quantity of lymphocytes with T-cell receptor (TCR) genes mutations. (innovations-report.com)
  • phenotype
  • Lymphocyte activation triggers multiple signalling cascades that converge in the cell nucleus to cause significant changes in the pattern of gene expression that determine the phenotype of activated lymphocytes and, ultimately, the type of immune response. (els.net)
  • 2001
  • S. J. McLeod and M. R. Gold, "Activation and function of the Rap1 GTPase in B lymphocytes," International Reviews of Immunology , vol. 20, no. 6, pp. 763-789, 2001. (hindawi.com)
  • Lewis CM, Broussard C, Czar MJ and Schwartzberg PL (2001) Tec kinases: modulators of lymphocyte signaling and development. (els.net)
  • Neutrophils
  • D.M. Lewinsohn, R.F. Bargatze, and E.C. Butcher, Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes, J. Immunol. (springer.com)
  • dendritic
  • Further characterization of the lymphocytes, accessory cells (dendritic cells, macrophage) and cytokines that participate in the MLR have been done as this assay continues to be used to define mechanisms for understanding cellular immune function in vitro. (wikipedia.org)
  • viral
  • A high lymphocyte count is referred to as lymphocytosis and is caused by a bacterial or viral infection, cancer, autoimmune disorders, tuberculosis, HIV/AI. (reference.com)
  • Reactive lymphocytes are usually associated with viral illnesses, but they can also be present as a result of drug reactions (such as phenytoin), immunizations, radiation, and hormonal causes (such as stress and Addison's disease), as well as some autoimmune disorders (such as rheumatoid arthritis). (wikipedia.org)
  • lymphocytosis
  • HealthCentral explains that lymphocytosis, or the presence of a high number of lymphocytes, can be caused by many different disorders and diseases, including mononucleosis, toxoplasmosis, AIDS and tuberculosis. (reference.com)
  • however, adults with more than 3,000 lymphocytes per milliliter of blood are generally considered to suffer from lymphocytosis. (reference.com)
  • In some cases, children must have more than 9,000 lymphocytes per milliliter of blood to be considered to suffer from lymphocytosis. (reference.com)
  • A person with a high lymph count could be suffering from a condition called lymphocytosis, an elevated level of white blood cells called lymphocytes. (reference.com)
  • resembles
  • The symptom of episodic angioedema in lymphocyte-variant hypereosinophilia resembles that occurring in Gleich's syndrome, a rare disease that is accompanied by secondary hypereosinophilia plus a sub-population of CD3(-), CD4(+) T cells and therefore proposed, at least in many patients, a subtype of lymphocyte-variant hypereosiophilia. (wikipedia.org)
  • cells
  • The Encyclopaedia Britannica states that lymphocytes are primarily categorized into B lymphocytes and T lymphocytes, also called B cells and T cells. (reference.com)
  • Lymphocytes generally last for a short time, with an average life span ranging from a week to a few months, although some cells live for years and form a group of long-lived T and B cells, according to the Encyclopaedia Britannica. (reference.com)
  • Lymphocytes are produced by the same stem cells that produce red blood cells. (reference.com)
  • Double increase of mutant lymphocyte frequency (more than 6.2 mutants per 10,000 cells) as compared to the background group was discovered with 37 percent of cancer patients, and this result cannot be considered accidental. (innovations-report.com)
  • T lymphocytes (T cells) are responsible for cell-mediated immunity. (howstuffworks.com)
  • Seventy-five percent of lymphocytes are T cells. (howstuffworks.com)
  • Lymphocytes, sometimes referred to as "fighter cells," attack infection-causing microorganisms. (ehow.co.uk)
  • Lymphocytes are white blood cells whose function is to fight off infection. (ehow.co.uk)
  • There are three major categories of lymphocytes: B-cells, T-cells and NK-cells. (ehow.co.uk)
  • lymphocytes, particularly T-cells, and have had trouble finding one. (bio.net)
  • They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation. (fpnotebook.com)
  • Tumor-infiltrating lymphocytes, also tumour infiltrating lymphocytes, are white blood cells that have left the bloodstream and migrated into a tumor. (wikipedia.org)
  • The three major types of lymphocyte are T cells, B cells and natural killer (NK) cells. (wikipedia.org)
  • Splenic lymphoma with villous lymphocytes is a rare type of lymphoma that involves mature B cells. (wikipedia.org)
  • Stimulator cell populations that also contain T-cells (Two way mixed lymphocyte reaction) will replicate in the presence of the Responder cells, therefore for a One way mixed lymphocyte reaction, stimulator cells are prevented from replicating by irradiation or treatment with mitomycin C, a DNA crosslinker to prevent cell replication. (wikipedia.org)
  • Clinically, this is similar to severe combined immunodeficiency (SCID), in which lymphocyte precursor cells are improperly formed. (wikipedia.org)
  • As a notable contrast, however, bare lymphocyte syndrome does not result in decreased B- and T-cell counts, as the development of these cells is not impaired. (wikipedia.org)
  • Donor leukocyte infusion is the infusion in which lymphocytes from the original stem cell donor are infused, after the transplant, to augment an anti-tumor immune response or ensure that the donor stem cells remain engrafted. (wikipedia.org)
  • Patients might require standard chemotherapy, to reduce the amount of cancer cells they have prior to their donor lymphocyte infusion. (wikipedia.org)
  • protein
  • This protein came to be known as Lymphocyte T-Cell Immunomodulator (LTCI). (wikipedia.org)
  • Lymphocyte expansion molecule (LEM) is a protein discovered in 2015, found to be involved in immune responses (in mice) to some cancers and viruses. (wikipedia.org)
  • Lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa), also known as LCP2 or SLP-76, is a gene that encodes a signal-transducing adaptor protein. (wikipedia.org)
  • infusion
  • Donor lymphocyte (or leukocyte) infusion (DLI) or buffy coat infusion is a form of adoptive immunotherapy used after hematopoietic stem cell transplantation. (wikipedia.org)
  • variant
  • Lymphocyte-variant hypereosinophila, also termed lymphocyte variant eosinophilia, is a rare disorder in which eosinophilia or hypereosinophilia (i.e. a large or extremely large increase in the number of eosinophils in the blood circulation) is caused by aberrant population of lymphocytes. (wikipedia.org)
  • Hence, lymphocyte-variant hypereosinophilia can be regarded as a precancerous disease. (wikipedia.org)
  • The typical patient with lymphocyte-variant hypereosinophilia presents with an extended history of hypereosinophilia and cutaneous allergy-like symptoms. (wikipedia.org)
  • Lymphocyte-variant hypereosinophilia usually takes a benign and indolent course. (wikipedia.org)
  • genes
  • The bare lymphocyte syndrome, type II (BLS II) is a rare recessive genetic condition in which a group of genes called major histocompatibility complex class II (MHC class II) are not expressed. (wikipedia.org)
  • interaction
  • E.C. Butcher, R.G. Scollay, and I.L. Weissman, Organ specificity of lymphocyte migration: Mediation by highly selective lymphocyte interaction with organ-specific determinants on high endothelial venules, Eur. (springer.com)
  • recognition
  • R.A. Rasmussen, Y-H Chin, J.J. Woodruff, and T.G. Easton, Lymphocyte recognition of lymph node high endothelium. (springer.com)
  • S. Jalkanen, R. Bargatze, L. Herron, and E.C. Butcher, A lymphoid cell surface glycoprotein involved in endothelial recognition and lymphocyte homing in man, Eur. (springer.com)
  • S. Jalkanen, R. Bargatze, M. Jalkanen, M. Tammi, and E.C. Butcher, Biochemical properties of glycoproteins involved in lymphocyte recognition of high endothelial venules in man, submitted. (springer.com)
  • cell
  • Lymphocyte T-Cell Immunomodulator is a single chain polypeptide that is a strongly cationic glycoprotein and is purified with cation exchange resin. (wikipedia.org)
  • Detection of gene expression specific for different kind of immune cell populations can then be used to determine the degree of lymphocyte infiltration as has been shown in breast cancer. (wikipedia.org)
  • If the mutated cell divides significantly, the resulting clonal population may be eliminated by a T lymphocyte response. (wikipedia.org)