RemifentanilMorphineOpioid painkillerSufentaDoseFentanyl and sufentanilAnesthesiaEpidural sufentanilIntrathecal sufentanilPropofolLabor AnalgesiaDsuviaCitratePotentMicrogramsConcentrationsLidocaineAnaphylaxisDosesIntraperitonealInductionIntravenous administrationIndicationsInjectionIntestinalRatsChronicDrugsDrugEffectsStudyGroupEffectAdministrationTreatmentPatientsGroupsResultsBloodMicro
Remifentanil4
- In this study, the investigators evaluate the effect of total intravenous anesthesia using sufentanil-remimazolam and remifentanil-remimazolam on postoperative pain in patients undergoing laparoscopic gastrectomy. (centerwatch.com)
- The main objective is the comparison of intubation conditions after anesthetic induction bolus of propofol-sufentanil when compared to injection of propofol-remifentanil in patients undergoing surgery for tooth extraction. (druglib.com)
- However, remifentanil was never compared to sufentanil in terms of intubating conditions without muscle relaxant. (druglib.com)
- Comparison of Intubation Conditions After Induction With Propofol Associated With a Dose of Remifentanil or Sufentanil in Surgical Tooth Extraction. (druglib.com)
Morphine8
- This study was designed to investigate the effects of dezocine, morphine and sufentanil on both intestinal smooth muscle contraction and propulsion in rats. (medsci.org)
- Contractile tension and frequency of isolated rat small intestine smooth muscle were measured using tension transducer after incubation with different concentrations of dezocine, morphine and sufentanil. (medsci.org)
- The propulsive rate of methylene blue in rat intestinal tract was measured 30 minutes after intraperitoneal injection of morphine, sufentanil and dezocine. (medsci.org)
- Morphine and sufentanil significantly increased the contractile tension of isolated small intestine smooth muscle at high doses. (medsci.org)
- The propulsive rate of methylene blue in intestinal tract was significantly decreased after the treatment with morphine, sufentanil and dezocine (45.6%, 43.7%, and 42.1% respectively) compared to control group(57.1%), while the difference among the 3 drug groups were not significant. (medsci.org)
- Morphine and sufentanil may dose dependently increase the contractile tension and contraction ability of isolated rat small intestine smooth muscle, while dezocine has no significant effect on intestine smooth muscle contraction. (medsci.org)
- An increase in illicit fentanyl production and distribution - it is often mixed into heroin or cocaine - has led to a spike in opioid overdose deaths around the United States because fentanyl and its analogs, like sufentanil, are much more potent than morphine and heroin. (serenityatsummit.com)
- It contains 30 micrograms of a synthetic opioid painkiller known as sufentanil, which is 5 to 10 times more potent than fentanyl, and 1,000 times more potent than morphine. (healthline.com)
Opioid painkiller2
- Currently sufentanil is the most potent opioid painkiller available for use in humans. (wikipedia.org)
- Dsuvia is a new brand name for a prescription opioid painkiller , sufentanil, which is a very potent narcotic analgesic. (serenityatsummit.com)
Sufenta2
- Sufentanil, sold under the brand names Dsuvia and Sufenta, is a synthetic opioid analgesic drug approximately 5 to 10 times as potent as its parent drug, fentanyl, and 500 times as potent as morphine. (wikipedia.org)
- Sufentanil is marketed for use by specialist centers[clarification needed] under different trade names, such as Sufenta and Sufentil. (wikipedia.org)
Dose9
- One group received intrathecal sufentanil (S) and the other group received the same dose of sufentanil plus supplemental bupivacaine (SB). (longdom.org)
- This study assessed and compared the characteristics of anaesthesia induced with combinations of sufentanil and medetomidine administered as a single subcutaneous or intraperitoneal dose, and reversal with butorphanol and atipamezole. (ncl.ac.uk)
- We studied 60 (randomised) patients who were to receive a 10 ml bolus dose of sufentanil , 1µg/ml, 2 µg/ml and3 µg/ml, in bupivacaine 0.125%, via thoracic epidural. (bvsalud.org)
- The present study aimed to determine the optimal sufentanil dose for epidural initiation in the latent and active phases during the first stage of labor. (bvsalud.org)
- A research dose of sufentanil combined with ropivacaine 13 mg in epidural initiation with a volume of 15 mL was administered to the puerperant. (bvsalud.org)
- A 1-microgram sufentanil dose and a 2.5-micrograms sufentanil dose were used for the first puerperant of each group. (bvsalud.org)
- The dose of sufentanil for the subsequent puerperant was determined by the response of the previous puerperant according to the biased coin up-and-down design in each trial. (bvsalud.org)
- The primary outcome was a visual analog scale score of administration , including the given dose of sufentanil . (bvsalud.org)
- Determination of the analgesic dose-response relationship for epidural fentanyl and sufentanil with bupivacaine 0.125% in laboring patients. (scielo.br)
Fentanyl and sufentanil1
- This research has been done to compare the effects of three drugs, epinephrine, fentanyl and sufentanil with lidocaine on spinal anesthesia to find the best drug. (ac.ir)
Anesthesia3
- General anesthesia was maintained with sevoflurane in oxygen and sufentanil infusion. (unicam.it)
- In one group (E) 0.2 mg epinephrine and in other group (F) 25 µg fentanyl and in the 3rd group (S) 2.5 µg sufentanil with 100 mg lidocaine 5% were used for spinal anesthesia. (ac.ir)
- Epidural anesthesia with bupivacaine, bupivacaine and fentanyl, or bupivacaine and sufentanil during intravenous administration of propofol for ovariohysterectomy in dogs. (scielo.br)
Epidural sufentanil1
- The aim of this prospective, double blind, randomised trial was to compare the analgesic and adverse effectsof three concentrations of the thoracic epidural sufentanil with bupivacaine in patients undergoing thoracotomy . (bvsalud.org)
Intrathecal sufentanil3
- The administration of intrathecal sufentanil plus bupivacaine seems to keep the hemodynamic status of the patients more stable than intrathecal sufentanil alone. (longdom.org)
- We report a series of six cases exhibiting a high sensory "block" after intrathecal sufentanil for labor analgesia. (silverchair.com)
- In each case, intrathecal sufentanil was administered as part of a combined spinal-epidural technique. (silverchair.com)
Propofol1
- Intubation without myorelaxant with propofol and sufentanil is classic but less efficient than induction with curare on achieving perfect intubation conditions. (druglib.com)
Labor Analgesia1
- ED90 of Sufentanil in Epidural Initiation for Labor Analgesia in Latent Phase and Active Phase During the First Labor Stage. (bvsalud.org)
Dsuvia1
- Dsuvia, in particular, and sufentanil in general, is designed to treat acute, severe pain when other pain medications are ineffective. (serenityatsummit.com)
Citrate4
- Sufentanil Citrate Injection, USP 50 mcg/mL (equivalent to 50 mcg/mL sufentanil base). (pfizermedicalinformation.com)
- Sufentanil Citrate Injection should be administered only by persons specifically. (pfizermedicalinformation.com)
- Sufentanil Citrate Injection contains sufentanil, a Schedule II controlled substance. (pfizermedicalinformation.com)
- Table 3 includes clinically significant drug interactions with Sufentanil Citrate Injection. (pfizermedicalinformation.com)
Potent2
- Although more potent narcotic pain medications do exist, all medications stronger than sufentanil are approved for veterinary use only. (wikipedia.org)
- citation needed] Because sufentanil is very potent, practitioners must be prepared to reverse the effects of the drug should the patient exhibit symptoms of overdose such as respiratory depression or respiratory arrest. (wikipedia.org)
Micrograms1
- The 90% effective doses of sufentanil for puerperants were 1.91 micrograms (95% confidence intervals 1.82-2.35 micrograms) and 4.90 micrograms (95% confidence intervals 4.82-5.35 micrograms) in epidural initiation in the latent and active phases, respectively. (bvsalud.org)
Concentrations1
- In this study, the authors examined whether intrathecally administered sufentanil has similar effects in pain-free individuals with low concentrations of progesterone (i.e., male volunteers). (silverchair.com)
Lidocaine1
- Sufentanil with and without lidocaine or mepivacaine is available as a transdermal patch similar to Duragesic in Europe under trade names such as Chronogesic. (wikipedia.org)
Anaphylaxis1
- Sufentanil has been associated with extremely rare instances of life-threatening anaphylaxis. (wikipedia.org)
Doses2
- Adamus M, Koutná J, Gabrhelík T, Zapletalová J. [Tracheal intubation without muscle relaxant--the impact of different sufentanil doses on the quality of intubating conditions: a prospective study]. (druglib.com)
- Different sufentanil doses should be adopted in epidural initiation in different phases during the first stage of labor due to the large differences in the demand for sufentanil . (bvsalud.org)
Intraperitoneal1
- Combinations of sufentanil/medetomidine at 40 μg/150 μg and 50 μg/150 μg/kg administered subcutaneously, and 80 μg/300 μg/kg by intraperitoneal injection were found to produce surgical anaesthesia for 101 ± 49, 124 ± 45 and 76 ± 23 min (means ± SD) respectively. (ncl.ac.uk)
Induction1
- The induction of anaesthesia with sufentanil/medetomidine and its reversal with a combination of atipamezole and butorphanol is an effective technique for anaesthetizing rats. (ncl.ac.uk)
Intravenous administration1
Indications1
- Indications de la curarisation en anesthésie : conférence de consensus (texte court). (druglib.com)
Injection1
- Ten male volunteers were randomly assigned to receive an intrathecal injection of either 10 microg sufentanil or saline in a double-blind fashion. (silverchair.com)
Intestinal1
- apalutamide will decrease the level or effect of sufentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
Rats2
- This study aims to explore the protective effects of sufentanil-postconditioning on myocardial cells in rats. (dpi-journals.com)
- Conclusion: Post-treatment with sufentanil alleviates myocardial ischemia-reperfusion injury in rats. (dpi-journals.com)
Chronic2
- This report describes the long term safety and efficacy of intrathecal therapy using Sufentanil for the management of chronic intractable neuropathic pain in 12 chronic pain patients. (epain.org)
- The purpose of the study is to describe the long-term safety and efficacy of intrathecal therapy using Sufentanil for the management of chronic intractable neuropathic pain, including failed back surgery syndrome. (epain.org)
Drugs1
- Although Dsuvia's primary ingredient, sufentanil, is a Schedule II medication, opioid drugs related to it (like fentanyl) have been diverted, produced illicitly, and widely abused. (serenityatsummit.com)
Drug1
- Pediatrics Central , peds.unboundmedicine.com/pedscentral/view/Davis-Drug-Guide/51817/all/SUFentanil. (unboundmedicine.com)
Effects2
- Depending on the amount administered, it can reverse the respiratory depression and, if enough is administered, completely reverse the effects of sufentanil. (wikipedia.org)
- The other effects of sufentanil, however, were similar to those observed in women undergoing labor. (silverchair.com)
Study1
- This study assesses the effect of intrathecal adjuvant bupivacaine plus sufentanil on intraoperative hemodynamic changes in elective coronary artery bypass surgery. (longdom.org)
Group3
- Structurally, sufentanil differs from fentanyl through the addition of a methoxymethyl group on the piperidine ring (which increases potency but is believed to reduce duration of action), and the replacement of the phenyl ring by thiophene. (wikipedia.org)
- Pruritus and sensory changes to pin prick and cold occurred in the sufentanil group but not the saline group. (silverchair.com)
- There was a small increase in the current perception thresholds at 250 Hz in the sufentanil group. (silverchair.com)
Effect1
- bremelanotide will decrease the level or effect of sufentanil by Other (see comment). (medscape.com)
Administration1
- But at the same time, the head of FDA's own advisory committee warned the administration that approval of the new version of sufentanil will only make overdoses that much more likely. (healthline.com)
Treatment1
- Intrathecal therapy with Sufentanil therapy offers a good treatment alternative for those cases that have failed both surgery and standard pain treatment. (epain.org)
Patients1
- In one report in which 20 [micro sign]g of intrathecally administered sufentanil (ITS) was given to men and women for lithotripsy, [5] no mention was made of hypotension, nausea was absent, and pruritus occurred in only 27% of the patients. (silverchair.com)
Groups1
- There was a clinically insignificant difference in the calf minus toe temperature index between the saline and sufentanil groups. (silverchair.com)
Results1
- [1,2] Whether the decrease in blood pressure results from a sympathectomy caused by weak local anesthetic action of sufentanil [1] or to pain relief remains controversial, although recent studies support the latter explanation. (silverchair.com)
Blood1
- Intrathecally administered sufentanil did not affect blood pressure in male volunteers. (silverchair.com)
Micro1
- Sufentanil, 10 micro gram, diluted to 1 or 2 ml with preservative-free saline, was injected and the spinal needle withdrawn. (silverchair.com)