AutophagyCell DeathApoptosisCause of DeathPhagosomesMicrotubule-Associated ProteinsApoptosis Regulatory ProteinsCell SurvivalCaspasesDeathSignal TransductionCell Line, TumorLysosomesMitochondriaNecrosisUbiquitin-Activating EnzymesCaspase 3TOR Serine-Threonine KinasesProto-Oncogene Proteins c-bcl-2Reactive Oxygen SpeciesModels, BiologicalCells, CulturedDNA FragmentationVacuolesCell LineClass III Phosphatidylinositol 3-KinasesMembrane ProteinsAdenineRNA, Small Interferingbcl-2-Associated X ProteinIn Situ Nick-End LabelingCaspase InhibitorsDeath, Sudden, CardiacCytoprotectionNeuronsRNA InterferenceEnzyme ActivationTime FactorsBlotting, WesternAntigens, CD95Microscopy, Electron, TransmissionAmino Acid Chloromethyl KetonesEndoplasmic Reticulum StressLysosomal-Associated Membrane Protein 2Membrane Potential, MitochondrialMutationAntineoplastic AgentsBrain DeathSirolimusCytochromes cOxidative StressCysteine Proteinase InhibitorsCaspase 8Cell ProliferationMitochondrial DegradationMice, KnockoutMice, Inbred C57BLTumor Suppressor Protein p53NeoplasmsPoly(ADP-ribose) PolymerasesHeLa Cellsbcl-X ProteinProteolysisChloroquineEndoplasmic ReticulumFetal DeathProteinsEnzyme InhibitorsNeurodegenerative DiseasesCaspase 9Adaptor Proteins, Signal TransducingGene Knockdown TechniquesFas Ligand ProteinProtein TransportProtein-Serine-Threonine KinasesTumor Cells, CulturedHydrogen PeroxideMicroscopy, FluorescenceTransfectionFibroblastsDNA DamageProto-Oncogene ProteinsCarrier ProteinsProteasome Endopeptidase ComplexGreen Fluorescent ProteinsStress, PhysiologicalPhosphorylationDose-Response Relationship, DrugReceptors, Death DomainDisease Models, AnimalMice, TransgenicApoptosis Inducing FactorAttitude to DeathFlow Cytometrybcl-2 Homologous Antagonist-Killer ProteinProto-Oncogene Proteins c-aktCell CycleGene Expression RegulationMultiprotein ComplexesDown-Regulation