Yokogawa CSU is renowned in microscopy field not only for the high image quality and fast capturing speed, but also for the live cell friendliness. (yokogawa.com)
Although manufacturers use the same technology for their urine chemical analyzers, the approach used for automated microscopy varies among three principles-digital flow morphology, flow cytometry, and digital microscopy using a cuvette or cell. (basicmedicalkey.com)
Analyzer2
Uses for flow cytometry include: Cell counting Cell sorting Determining cell characteristics and function Detecting microorganisms Biomarker detection Protein engineering detection Diagnosis of health disorders such as blood cancers Measuring genome size A flow cytometry analyzer is an instrument that provides quantifiable data from a sample. (wikipedia.org)
The ZE5 Cell Analyzer eliminates pain points that have hindered the full adoption of flow cytometry for drug discovery. (bioradiations.com)
20211
Meet us at International Conference Analytical Cytometry 2021. (accela.eu)
Assays3
With the advancement of technology, flow cytometers are now able to detect a much greater range of fluorescent dyes, facilitating the analysis of more extensive and complex multicolor immunophenotyping assays. (bioradiations.com)
Flow cytometry is an attractive alternative to imaging and plate reader assays for HTS in drug discovery, due to its increased sensitivity and multiplexing capabilities. (bioradiations.com)
Today's top choices (i.e., enzymatic assays, binding/immunoassays) will decrease somewhat in popularity to make room for cellular target engagement (CETSA), Label-free techniques like surface plasmon resonance (SPR), and HT FACS/Flow for primary blood cells. (perkinelmer.com)
Microfluidic4
The first label-free high-frequency impedance flow cytometer based on a patented microfluidic "lab-on-chip", Ampha Z30, was introduced by Amphasys (2012). (wikipedia.org)
This method forces the blood cells in a small drop of blood to flow extremely rapidly through a narrow microfluidic channel while they are imaged by a fast camera. (elifesciences.org)
The microfluidic devices include a cell capture chamber having a cell funnel positioned within the cell capture chamber to direct a cell passing through the cell capture chamber towards one or more a cell traps positioned downstream of the funnel to receive a cell flowing. (justia.com)
Microfluidic systems provide numerous advantages for single cell analysis: economies of scale, parallelization and automation, and increased sensitivity and precision that comes from small volume reactions. (justia.com)
Fluorescence4
The first fluorescence-based flow cytometry device (ICP 11) was developed in 1968 by Wolfgang Göhde from the University of Münster, filed for patent on 18 December 1968 and first commercialized in 1968/69 by German developer and manufacturer Partec through Phywe AG in Göttingen. (wikipedia.org)
Soon after, flow cytometry instruments were developed, including the Cytofluorograph (1971) from Bio/Physics Systems Inc. (later: Ortho Diagnostics), the PAS 8000 (1973) from Partec, the first FACS (fluorescence-activated cell sorting) instrument from Becton Dickinson (1974), the ICP 22 (1975) from Partec/Phywe and the Epics from Coulter (1977/78). (wikipedia.org)
citation needed] The original name of the fluorescence-based flow cytometry technology was "pulse cytophotometry" (German: Impulszytophotometrie), based on the first patent application on fluorescence-based flow cytometry. (wikipedia.org)
At the 5th American Engineering Foundation Conference on Automated Cytology in Pensacola (Florida) in 1976 - eight years after the introduction of the first fluorescence-based flow cytometer (1968) - it was agreed to commonly use the name "flow cytometry", a term that quickly became popular. (wikipedia.org)
Characteristics1
Flow cytometry (FC) is a technique used to detect and measure physical and chemical characteristics of a population of cells or particles. (wikipedia.org)
Cellular5
Cell-generated EV spike-in models were isolated and purified by size-exclusion chromatography, stained with cellular dyes and characterized by nano flow cytometry. (biomedcentral.com)
Address the full range of current and future multi-parameter cellular analysis research needs with the NovoCyte flow cytometer . (accela.eu)
Based on high-resolution microscopic images, high content analysis (HCA) enables you to detect cellular phenotypic changes at a molecular level, so the technology can be utilized as a powerful tool to study effects of physiologically active substances, such as compounds, siRNA, peptides and antibodies, on cultured cells, tissue samples and whole organisms, like zebrafish. (yokogawa.com)
Assessing a vast number of compounds is time consuming, therefore, acquiring a large number of high resolution cellular images with fast scanning speed is critically important for drug screening. (yokogawa.com)
Intravital imaging of pathophysiological cellular dynamics in natural in vivo microenvironment in various preclinical animal model can provide an unprecedented insight in the dynamic processes of human diseases beyond conventional histological observation of ex vivo sample or in vitro culture sample. (accela.eu)
Therapies1
This study demonstrates the existence and dissemination of high-affinity autoreactive plasma cells in multiple anatomical compartments of patients with ITP that may cause the failure of current therapies. (espci.fr)
Microscope2
A flow cytometer is similar to a microscope, except that, instead of producing an image of the cell, flow cytometry offers high-throughput, automated quantification of specified optical parameters on a cell-by-cell basis. (wikipedia.org)
In order to ensure high fidelity performance, we have implemented a high-speed microscope for in-process quality control, and image-based confluence measurements for automated dilution ratio calculation. (frontiersin.org)
Scientists1
For many scientists, high-throughput flow cytometry screens are associated with drug or compound libraries, but did you know that you can also apply this technique to study microorganisms, clinical melanoma samples, and even protein trafficking? (bioradiations.com)
Analysis4
citation needed] A flow cytometer has five main components: a flow cell, a measuring system, a detector, an amplification system, and a computer for analysis of the signals. (wikipedia.org)
Agilent provides xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers. (accela.eu)
Paired with our advanced analysis software, our HCA systems provide high quality 3D imaging for enhanced live cell analysis. (yokogawa.com)
Real-time2
Modern flow cytometers are able to analyze many thousands of particles per second, in "real time" and, if configured as cell sorters, can actively separate and isolate particles with specified optical properties at similar rates. (wikipedia.org)
now show that this is possible using a technique called real-time deformability cytometry. (elifesciences.org)
Life Sciences1
To lead in product development and partner with customers in solving everyday challenges, we gather information regularly about current practices and future trends," said Volker Eckelt, PhD, Senior Strategy Leader, PerkinElmer Life Sciences. (perkinelmer.com)
Fast1
In addition to the image aqcisition unit, precisely controled fast moving automated stage chamber is also an essensial component of our imaging systems. (yokogawa.com)
Technology2
Acting as a single dye detector with a billion nanowires per flow cell, this patented technology will enable a breakthrough in sequencing cost, throughput and read-length. (mediconbridge.se)
The core technology, the microlens-ehananced dual Nipokow disk in Yokogawa Confocall Scanner or Confocal Spinning disc Unit (CSU), makes it possible to capture high quality images with remarkably short aquisition time. (yokogawa.com)
High6
At both high (x ray) and low (radio frequency [RF]) energies the body is mostly transparent, thus allowing the non-invasive imaging of the internal structure of organs and bones. (nationalacademies.org)
The company offers high energy, high current, and medium current implanters for various application requirements. (danelfin.com)
Read on for five examples of the use of flow cytometry in diverse, high-throughput screening applications. (bioradiations.com)
ACEA brings researchers high performance flow cytometry at a low investment cost with the NovoCyte platform. (accela.eu)
We will present our high-content imaging devices with which you can elevate your organoid research to the next level. (yokogawa.com)
Our high-content confocal imaging systems based on the CSU are the ideal solution for drug screening using elaborated 3D and live cell assay systems as well as 2D fixed samples. (yokogawa.com)
Compound1
Bismuth iodide (BiI 3 ), lead iodide (PbI 2 ) and mercuric iodide (HgI 2 ) have theoretical gamma-ray detection efficiencies approximately 2-3 times higher than CdZnTe, the current compound semiconductor material proposed for use in several homeland/national security applications, over the range of 200-3000 keV. (spie.org)
Instruments2
Other instruments using flow cytometry include cell sorters which physically separate and thereby purify cells of interest based on their optical properties. (wikipedia.org)
You'll learn about innovation in biomedical imaging instruments produced by Spectral Instruments Imaging and Precision X-Ray, both from US. (accela.eu)
Methods1
Methods for cell capture and preparation are also provided that include flowing cells through a chamber, funneling the cells towards a cell trap, capturing a predefined number of the cells within the trap, interrupting the flow of cells, flowing a wash solution through the chamber to remove contaminants from the chamber, and sealing the predefined number of cells in the chamber. (justia.com)
Therapeutics1
Designed to recognize two distinct epitopes, bsAbs have enhanced binding, specificity, and efficacy compared to current monovalent antibody therapeutics, making them exciting candidates for more targeted cancer treatments. (bioradiations.com)
Analyzers1
Siemens Healthineers announced today the CE Mark and global commercial availability of its Atellica™ Solution-flexible, scalable, automation-ready immunoassay and chemistry analyzers. (cytofluidix.com)
Laboratory1
All image credit: Colder Product Company The in vitro diagnostics (IVD) market continues to grow at an almost breakneck pace, along with laboratory demands for increasingly complex and efficient equipment. (cytofluidix.com)
Tissue1
The amount of this intrinsic absorption can be used to determine the physiological health of an organ-for example, whether the tissue is getting sufficient oxygenated blood flow. (nationalacademies.org)
Software1
Acquisition is mediated by a computer physically connected to the flow cytometer, and the software which handles the digital interface with the cytometer. (wikipedia.org)
Digital1
The meeting is co-located with the 8th qPCR & Digital PCR Congress and the 3rd Flow Cytometry Congress . (global-engage.com)
As early as 1990s, the Research Institute for Advanced Computer Science at NASA's Ames Research Centre were collecting so much (complex) data leading their Director, Peter J Denning to comment, "The imperative to save all the bits forces us into an impossible situation: the rate and volume of information flow overwhelm our networks, storage devices and retrieval systems, as well as the human capacity for comprehension. (perkinelmer.com)
Process1
In this process, a sample containing cells or particles is suspended in a fluid and injected into the flow cytometer instrument. (wikipedia.org)
Device1
The device combines acoustic detection of turbulent arterial flow and myocardial movement with advanced algorithms in a handheld device to provide a patient specific CAD-score immediately on the device screen. (mediconbridge.se)
Research1
citation needed] Flow cytometry is routinely used in basic research, clinical practice, and clinical trials. (wikipedia.org)
Sample1
The sample is focused to ideally flow one cell at a time through a laser beam, where the light scattered is characteristic to the cells and their components. (wikipedia.org)
Liquid2
The flow cell has a liquid stream (sheath fluid), which carries and aligns the cells so that they pass single file through the light beam for sensing. (wikipedia.org)
and reagents for use in turbidimetry and flow cytometry, as well as develops liquid-based pharmacodiagnostics. (danelfin.com)