SpherocytosisDisorderDeficiencyHemoglobinHypoplasticBoneMacrocytic anemiaDefectsBillableClinicalBlood cellsIncludeTypeTestDescriptionHereditary hemolyticPyruvate kinase defAplasticFolateNormochromic and normocytic anemiaSyndromeDeficiencyMegaloblastic anemiaDisordersAcuteSickle cell diPrematurityThalassemiaMild anemiaChronic anemiaPopulationsSecondaryDiseaseSevereBloodIronSymptomsTreatmentNoteIndividualsPatientsHistoryFunction
Spherocytosis4
- any one of a group of congenital hemolytic anemias in which there is no abnormal hemoglobin or spherocytosis and in which there is a defect of glycolysis in the erythrocyte. (icdlist.com)
- This group is sometimes called congenital nonspherocytic (hemolytic) anemia , which is a term for a congenital hemolytic anemia without spherocytosis, and usually excluding hemoglobin abdormalities as well, but rather encompassing defects of glycolysis in the erythrocyte. (en-academic.com)
- hemolytic anemia that is present from birth and in which the lifespan of red blood cells is diminished, such as occurs in hereditary spherocytosis. (en-academic.com)
- Congenital hemolytic jaundice - Known also as hereditary spherocytosis (HS), this is a genetic disorder of the red blood cell membrane clinically characterized by anemia, jaundice (yellowing) and splenomegaly (enlargement of the spleen). (en-academic.com)
Disorder2
- a familial disorder characterized by anemia with multinuclear erythroblasts, karyorrhexis, asynchrony of nuclear and cytoplasmic maturation, and various nuclear abnormalities of bone marrow erythrocyte precursors (erythroid precursor cells). (icdlist.com)
- Glucose phosphate isomerase (GPI) deficiency is a rare autosomal recessive disorder that causes hereditary nonspherocytic hemolytic anemia (HNSHA). (biomedcentral.com)
Deficiency3
- hypochromic anemia may be caused by iron deficiency from a low iron intake, diminished iron absorption, or excessive iron loss. (icdlist.com)
- MCV, as well as MCH and MCHC, reflect average values and may not adequately reflect RBC changes where mixed RBC populations are present, such as dimorphic RBC populations in sideroblastic anemia or combined iron deficiency anemia (decreased MCV and MCH) and megaloblastic anemia (increased MCV). (medscape.com)
- Glucose-6-phosphate isomerase (GPI) deficiency (MIM 613470), one of hereditary nonspherocytic hemolytic anemias (HNSHA), is a rare autosomal recessive hereditary disease caused by homozygous or compound heterozygous mutations of GPI gene on chromosome 19q13 [ 1 ]. (biomedcentral.com)
Hemoglobin5
- a condition of inadequate circulating red blood cells (anemia) or insufficient hemoglobin due to premature destruction of red blood cells (erythrocytes). (icdlist.com)
- anemia characterized by a decrease in the ratio of the weight of hemoglobin to the volume of the erythrocyte, i.e., the mean corpuscular hemoglobin concentration is less than normal. (icdlist.com)
- anemia characterized by decreased or absent iron stores, low serum iron concentration, low transferrin saturation, and low hemoglobin concentration or hematocrit value. (icdlist.com)
- anemia characterized by larger than normal erythrocytes, increased mean corpuscular volume (mcv) and increased mean corpuscular hemoglobin (mch). (icdlist.com)
- He suffered from moderate hemolytic anemia (hemoglobin levels ranging from 62 to 91 g/L) associated with macrocytosis, reticulocytosis, neutropenia, and hyperbilirubinemia. (biomedcentral.com)
Hypoplastic1
- a rare congenital hypoplastic anemia that usually presents early in infancy. (icdlist.com)
Bone3
- a form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements. (icdlist.com)
- the disease is characterized by a moderate to severe macrocytic anemia, occasional neutropenia or thrombocytosis, a normocellular bone marrow with erythroid hypoplasia, and an increased risk of developing leukemia. (icdlist.com)
- [ 2 ] Of note, type of anemia can also be categorized based on bone marrow responses to anemia using reticulocyte count into hypoproliferative anemia (decreased red blood cell production) and hemolytic anemia (increased red blood cell destruction). (medscape.com)
Macrocytic anemia1
- sideroblastic anemia can be microcytic anemia, macrocytic anemia, or normochromic and normocytic anemia (due to the presence of dimorphic population of microcytes and macrocytes). (medscape.com)
Defects1
- hemolytic anemia due to various intrinsic defects of the erythrocyte. (icdlist.com)
Billable1
- D64.9 is a billable ICD-10 code used to specify a medical diagnosis of anemia, unspecified. (icdlist.com)
Clinical1
- In addition, once the causes of anemia are considered, correlation with clinical findings, including history and physical examination, is important, as is, when necessary, performing more definitive tests to arrive with a definitive diagnosis. (medscape.com)
Blood cells1
- acquired hemolytic anemia due to the presence of autoantibodies which agglutinate or lyse the patient's own red blood cells. (icdlist.com)
Include1
- Treatments for chronic hemolytic anemia include blood transfusions, splenectomy, and supportive therapy. (biomedcentral.com)
Type1
- Among these parameters, MCV is the most useful value used to classify the type of anemia based on red cell morphology. (medscape.com)
Test1
- Mean corpuscular volume (MCV) laboratory test, as part of a standard complete blood count (CBC), is used along with other RBC indices (MCH and MCHC) to help classify the cause of anemia based on red cell morphology. (medscape.com)
Description1
- Short description: Autoimmun hemolytic anem. (icd9data.com)
Hereditary hemolytic1
- C34376 Hemolytic Anemia C34379 Hereditary Hemolytic Anemia C99147 Neonatal Research Network Terminology C C34676 Sickle Cell-Hemoglobin C Disease Hemoglobin SC Disease Sickle Cell-Hemoglobin C Disease A hemoglobinopathy that is considered a hybrid of sickle cell disease and hemoglobin C disease. (nih.gov)
Pyruvate kinase def3
- Pyruvate kinase deficiency, one of the most common enzymatic defects of the erythrocyte, manifests clinically as a hemolytic anemia that can range from a mildly compensated anemia to severe anemia of childhood. (medscape.com)
- The birth history of patients with pyruvate kinase deficiency may include severe anemia, severe jaundice,[8] kernicterus, and a history of exchange transfusion. (medscape.com)
- Mitapivat is the first disease-modifying therapy approved for hemolytic anemia in adults with pyruvate kinase deficiency. (medscape.com)
Aplastic2
- For example, patients with sickle cell anemia who already have chronic anemia may develop additional acute anemia due to bone marrow failure (aplastic crisis). (medscape.com)
- Aplastic crisis - The so-called aplastic crisis may occur in any patients with chronic hemolytic anemia. (medscape.com)
Folate1
- Folate deficiency - Avoid folic acid deficiency by using supplementation in any patient with chronic hemolytic anemia. (medscape.com)
Normochromic and normocytic anemia1
- sideroblastic anemia can be microcytic anemia, macrocytic anemia, or normochromic and normocytic anemia (due to the presence of dimorphic population of microcytes and macrocytes). (medscape.com)
Syndrome1
- [ 59 ] and in post-diarrheal hemolytic uremic syndrome. (medscape.com)
Deficiency3
- MCV, as well as MCH and MCHC, reflect average values and may not adequately reflect RBC changes where mixed RBC populations are present, such as dimorphic RBC populations in sideroblastic anemia or combined iron deficiency anemia (decreased MCV and MCH) and megaloblastic anemia (increased MCV). (medscape.com)
- however, anemia that lasts only 2 months (eg, iron deficiency that is being treated) should also be considered chronic anemia, and the reasons for it must be sought. (medscape.com)
- For example, a retrospective study by Aljomah et al found that in pediatric patients with inflammatory bowel disease, 67.31% had anemia at diagnosis, with 38.46% having anemia of chronic disease by itself and 28.85% having iron deficiency anemia alone or suffering from both iron deficiency anemia and anemia of chronic disease. (medscape.com)
Megaloblastic anemia1
- Supplemental folic acid is used extensively in individuals with hemolytic anemia to prevent the development of megaloblastic anemia. (medscape.com)
Disorders1
- There is a general impression that additional studies should be carried out to establish the role and indications for EPO in hemolytic disorders. (medscape.com)
Acute3
- In contrast, acute anemia develops suddenly, in a matter of hours or days. (medscape.com)
- Acute anemia is usually due to acute blood loss or acute hemolysis. (medscape.com)
- An exception is acute anemia that occurs in patients with existing chronic anemia. (medscape.com)
Sickle cell di1
- The basic disease process is hematologic (eg, sickle cell disease, HS), and the degree of anemia varies markedly from etiology to etiology and from patient to patient, even with the same etiology. (medscape.com)
Prematurity1
- Go to Anemia and Anemia of Prematurity for complete information on these topics. (medscape.com)
Thalassemia1
- Iron overload - Monitor patients with primary chronic anemias to avoid iron overload (which can sometimes arise because of increased iron absorption, even in the absence of chronic transfusions) or expansion of the marrow cavity, as with thalassemia. (medscape.com)
Mild anemia2
- 9] The procedure does not abolish hemolysis or improve mild anemia, but it can reduce severe anemia and is frequently performed to minimize or eliminate the patient's need for blood transfusion. (medscape.com)
- On the other hand, pregnant women with even mild anemia have increased perinatal mortality and early neonatal mortality largely associated with preterm birth and growth restriction. (glowm.com)
Chronic anemia3
- Chronic anemia has no precise definition. (medscape.com)
- Chronic anemia can be primary or secondary. (medscape.com)
- Cerebral oxygen reduction - A study by Vu et al indicated that in patients with chronic anemia, the cerebral oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO 2 ) are reduced compared with controls. (medscape.com)
Populations1
- Anemia among women of reproductive age is so common that healthcare providers may consider it the norm, while epidemiologists note it as a marker for healthcare quality, and sociologists index it to disadvantaged populations. (glowm.com)
Secondary2
- Secondary chronic anemias are chronic anemias that may provide a diagnostic clue to an underlying pathology. (medscape.com)
- Complications that pose a threat to long-term health are often a function of the primary condition that is causing secondary anemia. (medscape.com)
Disease4
- For discussion of treatment of cold agglutinin hemolytic anemia, see Cold Agglutinin Disease . (medscape.com)
- Primary chronic anemias are the true chronic anemias, in which anemia (defined as a hemoglobin level more than 2 standard deviations below the mean reference value for age) is part of the basic disease process. (medscape.com)
- 4 Among low income women, the Centers for Disease Control and Prevention (CDC) found the prevalence of anemia to increase with gestation, noting 8%, 12%, and 29% in the first, second, and third trimester, respectively. (glowm.com)
- 7 For example, the physical functioning and vitality scores in women with postpartum anemia compare to scores seen with congestive heart failure, chronic renal disease and cancer patients. (glowm.com)
Severe4
- Most affected individuals do not require treatment, although in the most severe cases, death may occur in utero as a result of severe anemia. (medscape.com)
- Splenectomy is indicated only for patients with severe anemia. (medscape.com)
- 11 , 12 , 13 Anemia has also been linked to postpartum depression 14 and, if severe, can be related to cardiovascular symptoms, dizziness, and need for prolonged hospitalization. (glowm.com)
- 18 In summary, as providers we seem to have a problem with pregnancy associated anemia as we do not consider it to be an abnormality until it becomes quite severe. (glowm.com)
Blood1
- Mean corpuscular volume (MCV) laboratory test, as part of a standard complete blood count (CBC), is used along with other RBC indices (MCH and MCHC) to help classify the cause of anemia based on red cell morphology. (medscape.com)
Iron1
Symptoms1
Treatment1
- epub America's Deadliest Export: in unborn % which will be and hemolytic tissue in treatment and on knee survival it will become all amino macules and had another flat trial for developing ready weight. (reconcile-int.org)
Note1
- Of note, when considering the causes of anemia, the guidelines above are helpful but have limitations. (medscape.com)
Individuals1
Patients1
History1
- In addition, once the causes of anemia are considered, correlation with clinical findings, including history and physical examination, is important, as is, when necessary, performing more definitive tests to arrive with a definitive diagnosis. (medscape.com)