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  • platelets
  • Phagocytosis of autoantibody-opsonized platelets may be enhanced by components of infectious agents such as bacterial LPS ( 17 ). (jimmunol.org)
  • Immune thrombocytopenic purpura is a condition in which platelets are destroyed by an autoimmune process. (wikipedia.org)
  • TTP, as with other microangiopathic hemolytic anemias (MAHAs), is caused by spontaneous aggregation of platelets and activation of coagulation in the small blood vessels. (wikipedia.org)
  • Laboratory tests may also reveal low levels of platelets (cells in the blood that aid in clotting), elevated lactate dehydrogenase (LDH, a chemical released from damaged cells, and which is therefore a marker of cellular damage), decreased haptoglobin (indicative of the breakdown of red blood cells), anemia (low red blood cell count)/schistocytes (damaged red blood cells), elevated creatinine (indicative of kidney dysfunction), and proteinuria (indicative of kidney injury). (wikipedia.org)
  • RBCs
  • Anemia is a blood disorder characterized by abnormally low levels of healthy red blood cells (RBCs) or reduced hemoglobin (Hgb), the iron-bearing protein in red blood cells that delivers oxygen to tissues throughout the body. (encyclopedia.com)
  • severe anemia
  • Laboratory findings include severe anemia, increased mean corpuscular volume (MCV, due to the presence of a large number of reticulocytes), and hyperbilirubinemia (from increased red cell destruction) that can be of the conjugated or unconjugated type. (wikipedia.org)
  • Prednisone may be used in individuals with PCH and severe anemia. (wikipedia.org)
  • commonly
  • Signs and symptoms of anemia are commonly found, due to the association between T-LGLL and erythroid hypoplasia. (wikipedia.org)
  • IL-6 is the most commonly elevated cytokine, but some affected people may have normal IL-6 levels and present with non-iron-deficient microcytic anemia. (wikipedia.org)
  • Tissue
  • Ehrlich later adjusted his theory to recognize the possibility of autoimmune tissue attacks, but believed certain innate protection mechanisms would prevent the autoimmune response from becoming pathological. (wikipedia.org)
  • newborn
  • Anemia in newborn infants is noted when hemoglobin levels are lower than expected for the birth weight and postnatal age. (encyclopedia.com)