AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesNamed GroupsHealth CareGeographicals
ClonidineAustraliaWestern AustraliaAdrenergic alpha-AgonistsSouth AustraliaAdrenergic alpha-2 Receptor AgonistsQueenslandYohimbinePreanesthetic MedicationNew South WalesReceptors, Adrenergic, alpha-2SympatholyticsVictoriaNorthern TerritoryAdrenergic alpha-AntagonistsImidazoline ReceptorsReceptors, Adrenergic, alphaGuanfacineInjections, SpinalAnalgesicsOceanic Ancestry GroupIdazoxanAdrenergic alpha-2 Receptor AntagonistsAdjuvants, AnesthesiaOxymetazolinePrazosinNorepinephrineBlood PressureNew ZealandPhentolamineAnalgesia, EpiduralReceptors, AdrenergicPremedicationHeart RateDioxanesDouble-Blind MethodMorphineTasmaniaDose-Response Relationship, DrugGuanabenzAnesthetics, LocalHypnotics and SedativesNaloxoneHemodynamicsNeostigminePain, PostoperativeDexmedetomidineMedetomidineMethoxamineMethyldopaDrug InteractionsSympathetic Nervous SystemEpinephrineBupivacaineDesipramineInjections, Epidural
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Lowers blood pressure1
  • Clonidine lowers blood pressure by stimulating α2 receptors in the brain, which results in relaxation of many arteries. (wikipedia.org)
Opioid3
  • Clonidine has also been used to treat refractory diarrhea associated with irritable bowel syndrome, fecal incontinence, diabetes, diarrhea associated with opioid withdrawal, intestinal failure, neuroendocrine tumors, and cholera. (wikipedia.org)
  • Now a team of investigators [ 1 ] from the University of Adelaide, Australia, has undertaken a systematic review of 27 studies involving 3048 participants to assess the effects of buprenorphine versus tapered doses of methadone , alpha-2-adrenergic agonists, symptomatic medications or placebo, or different buprenorphine regimens for managing opioid withdrawal. (medscape.com)
  • The researchers found that buprenorphine is more effective than clonidine or lofexidine for managing opioid withdrawal and that buprenorphine and methadone appear to be equally effective. (medscape.com)
Withdrawal6
  • Clonidine may be used to ease drug withdrawal symptoms associated with abruptly stopping the long-term use of opioids, alcohol, benzodiazepines and nicotine. (wikipedia.org)
  • In infants with neonatal withdrawal syndrome, clonidine may improve the neonatal intensive care unit Network Neurobehavioral Score. (wikipedia.org)
  • Clonidine has also been suggested as a treatment for rare instances of dexmedetomidine withdrawal. (wikipedia.org)
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  • Clonidine can be used to relieve the withdrawal and containment symptoms associated with the use of long-term narcotics and alcohol, such as benzodiazepines and nicotine (smoking). (scopeheal.com)
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ADHD4
  • In Australia, clonidine is an accepted but not approved use for ADHD by the TGA. (wikipedia.org)
  • Clonidine, along with methylphenidate, has been studied for treatment of ADHD. (wikipedia.org)
  • Clonidine has been used to reduce sleep disturbances in ADHD, including to help offset stimulant-associated insomnia. (wikipedia.org)
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Hypertension1
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Tics2
  • Clonidine can be used in the treatment of Tourette syndrome (specifically for tics). (wikipedia.org)
  • Clonidine can be used to treat Tourette syndrome (precisely to control or decrease tics). (scopeheal.com)
Tablets3
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Dose1
  • The trial separately randomized 10 010 patients at 135 centers in 23 countries to receive low-dose clonidine (n=5009) vs placebo (n=5001) and low-dose aspirin (n=4998) vs placebo (n=5012). (medscape.com)
Sedative1
Attention deficit4
  • Clonidine may improve symptoms of attention deficit hyperactivity disorder in some people but causes many adverse effects and the beneficial effect is modest. (wikipedia.org)
  • The United States Food and Drug Administration (FDA) has approved Clonidine to treat attention deficit hyperactivity disorder, under Kapvay alone or with stimulants in 2010, for pediatric patients between 6 and 17 years. (scopeheal.com)
  • The Therapeutic Goods Administration (Clonidine) is an accepted but not approved use for attention deficit hyperactivity disorder in Australia. (scopeheal.com)
  • The contiguous Clonidine with methylphenidate has been studied for attention deficit hyperactivity disorder medication and treatment. (scopeheal.com)
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Hypotension3
  • And with clonidine, there were significant increases in clinically important hypotension and bradycardia and in nonfatal cardiac arrest. (medscape.com)
  • clonidine may reduce hypertensive swings only to be countered by clinically important hypotension. (medscape.com)
  • Considering these findings, a clinical trial for the use of clonidine in the treatment of persistent vasopressor-refractory hypotension in patients with septic shock would be worthwhile. (monash.edu)
Medications1
  • There are several online pharmacies based in Australia that allow you to purchase medications and health-related products over the internet. (rx24scan.com)
Beta-blockers1
  • Dr John A Jarcho (Brigham and Women's Hospital, Boston, MA), speaking at a briefing on POISE-2 for the media, pointed out that clonidine blocks the sympathetic nervous system and that beta-blockers do the same thing but by a difference mechanism. (medscape.com)
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Menopause1
  • Clonidine can also be used for migraine headaches and hot flashes associated with menopause. (wikipedia.org)
Postoperative1
  • However, the potential use of Clonidine for postoperative pain relief requires further investigation. (scopeheal.com)
Anxiety1
  • Clonidine also has several off-label uses, and has been prescribed to treat psychiatric disorders including stress, sleep disorders, hyperarousal caused by post-traumatic stress disorder, borderline personality disorder, and other anxiety disorders. (wikipedia.org)
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Infants1
  • Clonidine may also reduce severity of neonatal abstinence syndrome in infants born to mothers that are using certain drugs, particularly opioids. (wikipedia.org)
Sympathetic3
  • We therefore examined the effects of the alpha2-adrenergic agonist clonidine on mean arterial pressure, renal sympathetic nerve activity, and pressor responsiveness to phenylephrine and angiotensin II during hypotensive sepsis in conscious sheep. (monash.edu)
  • Clonidine treatment prevented the further decline in mean arterial pressure, substantially reduced heart rate and renal sympathetic nerve activity and restored pressor responsiveness to both phenylephrine and angiotensin II toward preseptic levels. (monash.edu)
  • CONCLUSIONS: Administration of clonidine during hypotensive sepsis reduced renal sympathetic nerve activity, restored vascular sensitivity to both phenylephrine and angiotensin II, and resulted in better preservation of arterial pressure. (monash.edu)
Prices1
  • Catapres (Clonidine) Prices and the Best Way to SaveWe do not have access to real-time information o. (rx24scan.com)
Drug2
  • WASHINGTON, DC - Neither aspirin nor clonidine reduced the risk of death or nonfatal MI when given in conjunction with noncardiac surgery, a large trial demonstrated using separate double-blind randomizations for each drug [ 1 , 2 ] . (medscape.com)
  • The food and drug administration approved Clonidine in September 1974. (scopeheal.com)
Surgery3
  • Injection of α2 receptor agonists into the knee joint space, including clonidine, may reduce the severity of knee pain after arthroscopic knee surgery. (wikipedia.org)
  • Clonidine was given as 0.2 mg/day two to four hours before surgery and continued for 72 hours after surgery. (medscape.com)
  • Administering Clonidine to children before surgery may help relieve pain after an operation. (scopeheal.com)
Work2
  • What is Clonidine, and how does it work? (scopeheal.com)
  • These guidelines also build on work conducted in Australia on assisting smoking cessation and on other risk factors for preventable disease. (who.int)
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Reduction1
  • Clonidine works by slowing the pulse rate and exerts a reduction of serum concentrations of renin, aldosterone, and catecholamines. (wikipedia.org)