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  • immune
  • 2. A method of ablating normal cells in the spleen in immune disease by parenterally administering an unconjugated monoclonal antibody which targets normal cells in the spleen and is directed against normal and malignant B-cells. (google.com)
  • uterus
  • Like lignans, many bioflavonoids are estrogenic and can help to regulate the effects of our own body's estrogen on sensitive target tissue like the breast and uterus. (healthy.net)
  • While the hamartomas are benign, people with Cowden syndrome are at increased risk of certain forms of cancer, including breast, thyroid, uterus (endometrial), and kidney cancers. (wikipedia.org)
  • however, people with Cowden syndrome are at increased risk of developing several types of cancer, including cancers of the breast, thyroid, uterus (endometrial), and kidney cancers. (wikipedia.org)
  • tissue
  • Cowden syndrome (also known as Cowden's disease and sometimes as multiple hamartoma syndrome) is a rare autosomal dominant inherited disorder characterized by multiple non-cancerous tumor-like growths called hamartomas, which typically are found in the skin, mucous membranes (mouth, nasal membranes, GI tract), thyroid gland, and breast tissue. (wikipedia.org)
  • At the front of the chest, the breast tissue can extend from the clavicle (collarbone) to the middle of the sternum (breastbone). (wikipedia.org)
  • At the sides of the chest, the breast tissue can extend into the axilla (armpit), and can reach as far to the back as the latissimus dorsi muscle, extending from the lower back to the humerus bone (the longest bone of the upper arm). (wikipedia.org)
  • and glandular tissue, which affects the lactation functions of the breasts. (wikipedia.org)
  • The tissue composition ratios of the breast also vary among women. (wikipedia.org)
  • Some women's breasts have varying proportions of glandular tissue than of adipose or connective tissues. (wikipedia.org)
  • The fat-to-connective-tissue ratio determines the density or firmness of the breast. (wikipedia.org)
  • develop
  • People with Cowden syndrome develop characteristic lesions called hamartomas, which are small, noncancerous growths that are most commonly found on the skin and mucous membranes (such as the lining of the mouth, nose, and intestines), but can also occur other parts of the body, such as the thyroid and breast. (wikipedia.org)
  • skin
  • Milk exits the breast through the nipple, which is surrounded by a pigmented area of skin called the areola. (wikipedia.org)
  • benign
  • While the hamartomas are benign, people with Cowden syndrome are at increased risk of certain forms of cancer, including breast, thyroid, uterus (endometrial), and kidney cancers. (wikipedia.org)
  • These mutations lead to characteristic features including macrocephaly, intestinal hamartomatous polyps, benign skin tumors (multiple trichilemmomas, papillomatous papules, and acral keratoses) and dysplastic gangliocytoma of the cerebellum (Lhermitte-Duclos disease). (wikipedia.org)
  • changes
  • Alzheimer's disease - A progressive, incurable condition that destroys brain cells, gradually causing loss of intellectual abilities - such as memory - and extreme changes in personality and behavior. (nyhq.org)
  • development
  • During pregnancy, the breast responds to a complex interaction of hormones, including estrogens, progesterone, and prolactin, that mediate the completion of its development, namely lobuloalveolar maturation, in preparation of lactation and breastfeeding. (wikipedia.org)
  • body
  • The primary tumor begins in the breast itself, but once it becomes invasive, it may progress beyond the breast to the regional lymph nodes or travel (metastasize) to other organ systems in the body and become systemic in nature. (thefreedictionary.com)