• ventral
  • During headfold formation (E8.0), expression is seen in the ventral foregut endoderm adjacent to the heart and in endocardial cells of the developing cardiac tubes, but not in the intervening myocardial cell layer. (biologists.org)
  • extracellular matrix
  • The cushion is made up of extracellular matrix components initially, but as endocardial endothelial cells are stimulated to undergo endothelial to mesenchymal transdifferentiation (EMT), the cellularity of the cushion increases as a result of the migration of endothelial cells ( 9 ). (pubmedcentralcanada.ca)
  • A zebrafish mutant embryo, called the jekyll mutant has a disruption in the gene encoding uridine 5′-diphosphate glucose dehydrogenase, which is essential for the synthesis of hyaluronic acid, an abundant component of the extracellular matrix in endocardial cushions ( 15 ). (pubmedcentralcanada.ca)
  • EC formation occurs via an epithelial-mesenchymal transformation (EMT), involving transformation of endocardial cells into mesenchymal cells, migration, and invasion into extracellular matrix. (rupress.org)
  • coronary
  • Finally, there is a rare defect called coronary sinus ASD, which is a failure of development of the separation of the coronary sinus from the left atrium, which allows left atrial blood to enter the right atrium through the orifice of the coronary sinus. (renalandurologynews.com)
  • We show that sinus venosus endocardial sprouts and proepicardial angioblasts pioneer coronary vascular formation, invading the developing heart simultaneously. (readbyqxmd.com)