• Nevertheless, my EBT scan revealed a calcium score in my left anterior descending coronary artery-- the one that's nicknamed the "widow maker," because if it clogs, you can die--of 121.54. (cnn.com)
  • The medical examiner found severe atherosclerosis of the left anterior descending coronary artery and left circumflex coronary artery. (cdc.gov)
  • Coronary artery disease (CAD), also called coronary heart disease (CHD), ischemic heart disease (IHD), myocardial ischemia, or simply heart disease, involves the reduction of blood flow to the heart muscle due to build-up of atherosclerotic plaque in the arteries of the heart. (wikipedia.org)
  • On the other hand, nearly everyone agrees that EBTs are very good at detecting coronary plaque, or atherosclerosis--especially in patients who seem perfectly fine. (cnn.com)
  • This build-up is called "atherosclerotic plaque" or simply "plaque. (medtronic.com)
  • Plaque deposits can clog the coronary arteries and make them stiff and irregular. (medtronic.com)
  • The term atherosclerosis is derived from the Greek "athero," meaning gruel, or wax, corresponding to the necrotic core area at the base of the atherosclerotic plaque, and "sclerosis" for hardening, or induration, referring to the fibrous cap of the plaque's luminal edge. (medscape.com)
  • The etiology of atherosclerosis is unknown, but there are multiple factors that contribute to atherosclerotic plaque progression. (medscape.com)
  • We previously demonstrated that factor XI (FXI) deficiency in mice reduced the atherosclerotic plaque area in coronary sinuses and the aortic arch. (spandidos-publications.com)
  • ACS is a group of clinical syndromes, including non-ST elevation acute coronary syndrome (NSTE-ACS) and ST elevation acute myocardial infarction (STEMI), with the pathogenesis of vulnerable plaque rupture, subsequent red or white thrombosis, thereby resulting in incomplete or complete vascular occlusion [ 4 ]. (hindawi.com)
  • It is often asymptomatic early in the course of the disease but may lead to chest pain (angina) and/or heart attack with progressive development of narrowing (stenosis) or plaque rupture of the arterial wall. (scienceblog.com)
  • Smad3 regulates smooth muscle cell fate and mediates adverse remodeling and calcification of the atherosclerotic plaque. (stanford.edu)
  • Background: Smooth muscle cells (SMC) transition into a number of different phenotypes during atherosclerosis, including those that resemble fibroblasts and chondrocytes, and make up the majority of cells in the atherosclerotic plaque. (stanford.edu)
  • Coronary artery disease (CAD) is characterized by atherosclerotic plaque formation in the coronary arteries and underlies ischaemic heart disease, the leading cause of death worldwide. (thrombosisadviser.com)
  • 1, 2 Rupture of an atherosclerotic plaque can lead to the formation of a blood clot in the artery. (thrombosisadviser.com)
  • This promotes the formation of artery-blocking plaque, resulting in atherosclerosis , a narrowing of the arteries that restricts blood flow. (lifeextension.com)
  • The type of artery and where the plaque develops varies with each person. (health-care-articles.info)
  • It is caused by the slow buildup of plaque on the inside of walls of the arteries. (health-care-articles.info)
  • Hard plaque causes artery walls to thicken and harden. (health-care-articles.info)
  • Cardiac imaging is central to the diagnosis and risk stratification of coronary artery disease, beyond symptoms and clinical risk factors, by providing objective evidence of myocardial ischaemia and characterisation of coronary artery plaque. (bmj.com)
  • CT coronary angiography can detect coronary plaque with high resolution, estimate the degree of functional stenosis and characterise plaque features. (bmj.com)
  • However, coronary artery disease risk is also driven by biological processes, such as inflammation, that are not fully reflected by severity of stenosis, myocardial ischaemia or by coronary plaque features. (bmj.com)
  • New cardiac CT techniques can assess coronary artery inflammation by imaging perivascular fat, and this may represent an important step forward in identifying the 'residual risk' that is not detected by plaque or ischaemia imaging. (bmj.com)
  • Coronary artery disease risk assessment that incorporates clinical factors, plaque characteristics and perivascular inflammation offers a more comprehensive individualised approach to quantify and stratify coronary artery disease risk, with potential healthcare benefits for prevention, diagnosis and treatment recommendations. (bmj.com)
  • Intravascular imaging, using ultrasound (IVUS) or optical coherence tomography, reveals that angiographic assessment of the coronary lumen grossly underestimates the presence, nature and extent of coronary artery plaque. (bmj.com)
  • Percutaneous transluminal coronary rotational atherectomy (PTCRA) debulks atherosclerotic plaque from coronary arteries using an abrasive burr. (cochrane.org)
  • Most heart attacks occur because of atherosclerotic plaque but, unfortunately, atherosclerosis often remains asymptomatic, delaying treatment until too late. (naturemedclinic.com)
  • Goal LDL (to prevent atherosclerotic plaque formation) is between 50-70 mg/dL. (medscape.com)
  • Further metabolism of the VLDL results in the cholesterol rich LDL, which is the key ingredient for the development of an atherosclerotic plaque. (medscape.com)
  • This problem occurs when fatty material (plaque) builds up on the walls of your arteries and makes them narrower. (medlineplus.gov)
  • PET/CT (positron emission tomography/computed tomography) is used to diagnose or determine the severity of many diseases, such as cancer . (healthgrades.com)
  • Coronary computed tomography angiography (CCTA) is a noninvasive method to image the coronary arteries. (medscape.com)
  • 2013) Non-Obstructive Coronary Artery Disease Documented by Cardiac Computed Tomography: Discrepancy between Atherosclerotic Burden and Cardiovascular Risk. (scirp.org)
  • This was a prospective, observational study which included 545 adult men who underwent multi-slice computed tomography (CT) coronary angiography for suspected coronary artery disease. (sunstar.com.ph)
  • The current authors conducted a retrospective study of 61 patients with both emphysema of the upper zones and diffuse parenchymal lung disease with fibrosis of the lower zones of the lungs on chest computed tomography. (ersjournals.com)
  • The earliest pathologic descriptions of atherosclerotic lesions focused on morphologies of fatty streaks to fibroatheromas (FAs) and advanced plaques complicated by hemorrhage, calcification, ulceration, and thrombosis. (medscape.com)
  • The latter is a neurodegenerative disease, which is characterized by dementia, along with a dense deposition of amyloid-β (Aβ) protein in senile plaques in the brain, hyperphosphorylated tau protein and neuron loss. (spandidos-publications.com)
  • Periodontal pathogens have been found in carotid and coronary atherosclerotic plaques. (medscape.com)
  • Smooth muscle cells (SMCs), the major cell type in atherosclerotic plaques, are vital in coronary artery diseases (CADs). (stanford.edu)
  • Smooth muscle cell (SMC) phenotypic transition, which leads to the formation of various cell types in atherosclerotic plaques, is regulated by a network of genetic and epigenetic mechanisms and governs the risk of disease. (stanford.edu)
  • Atherosclerotic plaques consist mostly of smooth muscle cells (SMC), and genes that influence SMC phenotype can modulate coronary artery disease (CAD) risk. (stanford.edu)
  • Angiotensin II is produced primarily by angiotensin I-converting enzyme (ACE) within atherosclerotic lesions and ACE level in plaques correlates with the severity of vessel wall damage. (degruyter.com)
  • It is a disease of the arterial intima leading to the formation of fibrous plaques and to stenosis/ occlusion of the lumen. (health-care-articles.info)
  • PTCRA utilises small rotating devices to selectively remove the build-up of atherosclerotic plaques from within coronary vessels. (cochrane.org)
  • Its ongoing effectiveness and safety compared with other modes of removing atherosclerotic plaques is reviewed. (cochrane.org)
  • Atherosclerosis Atherosclerosis is a condition in which patchy deposits of fatty material (atheromas or atherosclerotic plaques) develop in the walls of medium-sized and large arteries, leading to reduced or. (msdmanuals.com)
  • Patients with coronary artery disease had a statistically significant higher hair whitening score and higher coronary artery calcification than those without coronary artery disease. (sunstar.com.ph)
  • CCT imaging for CAD initially quantified coronary artery calcification, as it was readily detected on CT images, and quantified to generate a coronary artery calcium score (CACS) that represented a surrogate marker of the presence and extent of CAD. (bmj.com)
  • Prevalence and extent of coronary artery calcification in an asymptomatic cardiovascular Mexican population: Genetics of Atherosclerotic Disease study]. (bvsalud.org)
  • A number of tests may help with diagnoses including: electrocardiogram, cardiac stress testing, coronary computed tomographic angiography, and coronary angiogram, among others. (wikipedia.org)
  • Additional models examined subsets of cardiac disease and all-cause death as outcomes, as well as adjusting for noncardiac death volume. (cdc.gov)
  • Her current research is focused on investigating the prevalence and determinants of cardiac dysfunction, and coronary artery disease, in rural Uganda, along with her multi-disciplinary mentorship team lead by Mark Siedner, MD, MPH. (massgeneral.org)
  • Dr. Samuel said asymptomatic patients at high risk of coronary artery disease should have regular check-ups to avoid early cardiac events by initiating preventive therapy. (sunstar.com.ph)
  • Patients With Acute Coronary Syndromes Admitted to Contemporary Cardiac Intensive Care Units: Insights From the CCCTN Registry. (ucsd.edu)
  • Finding acute coronary syndrome with serial troponin testing for rapid assessment of cardiac ischemic symptoms (FAST-TRAC): a study protocol. (ucsd.edu)
  • Cardiac CT (CCT) imaging has transformed the detection, characterisation and stratification of coronary artery disease (CAD) risk in individuals. (bmj.com)
  • The most common cause of mortality worldwide is cerebrovascular disease (CVD), which includes coronary heart disease (CHD), congestive heart failure, CVD and stroke, peripheral artery diseases, carotid artery diseases, and aortoiliac disease. (medscape.com)
  • therefore, the association between certain periodontal pathogens and coronary artery disease or stroke is gaining more importance. (medscape.com)
  • Atherosclerotic cardiovascular disease (ASCVD), coronary artery disease, and stroke stand as the leading causes of morbidity and mortality globally. (helsinkitimes.fi)
  • Inadequate magnesium levels have been linked with an increased risk for cardiovascular disease, including stroke, coronary heart disease, heart failure, arrhythmias , and death. (lifeextension.com)
  • Despite significant medical advances, coronary artery disease and atherosclerotic stroke are responsible for more deaths than all other causes combined. (health-care-articles.info)
  • Variations in ApoE affect cholesterol metabolism, which in turn alter your chances of having heart disease and in particular a heart attack or a stroke. (feedburner.com)
  • and may prevent long-term health problems, such as coronary heart disease, cancer, and stroke. (cdc.gov)
  • Methods: In the Malmö Diet and Cancer Study-cardiovascular cohort, 5,381 participants were free from atrial fibrillation or flutter, AD (coronary artery disease, atherothrombotic ischemic stroke, carotid artery disease, or peripheral artery disease), and AAA underwent blood sampling under standardized fasting conditions between 1991 and 1994. (lu.se)
  • Cases of ASCVD - defined as coronary artery disease (CAD), ischemic stroke , or acute complications - were identified via hospital records and death registry. (medscape.com)
  • To demonstrate the superiority of inclisiran compared to placebo in reducing the risk of 4P-MACE (composite of CV death, non-fatal MI, non-fatal ischemic stroke, and urgent coronary revascularization)Timepoint: Time to the first occurrence of 4P-MACE at every visit. (who.int)
  • In total, 1,168 patients with normal coronary arteries were included in the control group, while 1,369 patients with CAD with obstruction equal or above 75% in at least a single coronary artery or ≥ 50% in the left main coronary artery made up the case group. (scienceblog.com)
  • It is the most common of the cardiovascular diseases. (wikipedia.org)
  • We confirm that HIIT is effective for improving vascular function in individuals with metabolic disorders and cardiovascular diseases and has a superior effect compared to MICT, demonstrating time efficiency," the researchers concluded. (activistpost.com)
  • World Journal of Cardiovascular Diseases , 4 , 211-216. (scirp.org)
  • Fellows can choose their own research theses with reference to variety of research topics listed below, and are expected to obtain competence in basic and clinical knowledge in the field of cardiovascular diseases. (juntendo.ac.jp)
  • [ 5 , 7 ] Although the underlying mechanisms are complex, the chronic inflammatory state and microbial burden in people with periodontal disease may predispose them to cardiovascular diseases in ways proposed for other infections. (medscape.com)
  • The Tulane study, utilizing data from the UK Biobank collected from 450,000 adults, assessed participants' susceptibility to cardiovascular diseases based on family history, established risk factors, and genetic predispositions. (helsinkitimes.fi)
  • Fisetin, a flavonoid phytonutrient present in almost all kinds of fruits and vegetables, has recently emerged as a powerful antioxidant for health promotion [ 9 , 10 ] and exerts multiple protective effects in different oxidative stress-related conditions in human, such as degenerative diseases (e.g., vascular dementia), cancer, diabetes, and cardiovascular diseases [ 11 - 14 ]. (hindawi.com)
  • My laboratory is engaged in system biology approaches to investigate cardiovascular diseases. (yale.edu)
  • The drawings focus primarily on blockages in the following arteries: left anterior descending (LAD) artery, left main coronary artery, circumflex artery, and the right coronary artery. (smartimagebase.com)
  • The right coronary artery and the left coronary artery, which branch off the aorta just after it leaves the heart, deliver oxygen-rich blood to the heart muscle. (msdmanuals.com)
  • The right coronary artery branches into the marginal artery and the posterior interventricular artery, located on the back surface of the heart. (msdmanuals.com)
  • LDL-C is one of the major culprits in the development of atherosclerotic heart disease. (medscape.com)
  • Lesion reference to AHA types V and VI was discarded, because it failed to account for the 3 different morphologies (rupture, erosion, and calcified nodule) that give rise to acute coronary thrombosis. (medscape.com)
  • This battery of measurements are used in the diagnosis and treatment of certain liver, heart, and kidney diseases, acid-base imbalance in the respiratory and metabolic systems, other diseases involving lipid metabolism and various endocrine disorders as well as other metabolic or nutritional disorders. (cdc.gov)
  • Alanine aminotransferase measurements are used in the diagnosis and treatment of certain liver diseases (e.g., viral hepatitis and cirrhosis) and heart diseases. (cdc.gov)
  • Alkaline phosphatase measurements are used in the diagnosis and treatment of liver, bone, and parathyroid disease. (cdc.gov)
  • AST measurements are used in the diagnosis and treatment of certain types of liver and heart disease. (cdc.gov)
  • BUN measurements are used in the diagnosis of certain renal and metabolic diseases. (cdc.gov)
  • Calcium measurements are used in the diagnosis and treatment of parathyroid disease, bone diseases, chronic renal disease and tetany. (cdc.gov)
  • Creatinine measurements are useful in the diagnosis and treatment of renal diseases. (cdc.gov)
  • Iron (non-heme) measurements are used in the diagnosis and treatment of diseases such as iron deficiency anemia, chronic renal disease, and hemochromatosis (a disease associated with widespread deposit in the tissues of two iron-containing pigments, hemosiderin and hemofuscin, and characterized by pigmentation of the skin). (cdc.gov)
  • Patients with connective tissue disease at the time of the diagnosis of CFPE were excluded from the study, as well as patients with a diagnosis of other interstitial lung diseases, such as drug-induced interstitial lung disease, pneumoconiosis, hypersensitivity pneumonitis, sarcoidosis, pulmonary histiocytosis, lymphangioleiomyomatosis and eosinophilic pneumonia 4 . (ersjournals.com)
  • ESC Guidelines on the diagnosis and treatment of peripheral artery diseases: document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries: the task force on the diagnosis and treatment of peripheral artery diseases of the European Society of Cardiology (ESC). (thrombosisadviser.com)
  • Consequently, invasive coronary angiography (ICA) became the gold standard for diagnosis of CAD. (bmj.com)
  • It is a chronic inflammatory disease of the arterial wall, which is characterized by lipid accumulation, leukocyte infiltration and smooth muscle cell proliferation. (spandidos-publications.com)
  • In line with the ageing population, the prevalence of coronary artery disease (CAD), lower extremity peripheral arterial disease (PAD), supra-aortic arterial disease (SAD) and renal stenosis (RAS) is increasing. (who.int)
  • Therefore, we investigated the possible association of ACE gene insertion/deletion (I/D) polymorphism and the severity of atherosclerosis, estimated on the basis of the number of coronary stenoses and critical arterial occlusions observed during coronary angiography. (degruyter.com)
  • In addition, the thickness of the carotid artery-a measure of unhealthy arterial thickening-rose in placebo patients but remained unchanged in magnesium- treated patients. (lifeextension.com)
  • Deficiencia de vitamina D y su asociación con enfermedad arterial coronaria en población mexicana: estudio Genético de la Enfermedad Aterosclerosa. (bvsalud.org)
  • Prevalencia y extensión de la calcificación arterial coronaria en población mexicana asintomática cardiovascular: estudio Genética de la Enfermedad Aterosclerosa. (bvsalud.org)
  • To investigate whether the use of statin is associated with a risk reduction in lower-extremity amputation in type 2 diabetes mellitus (DM) patients with peripheral arterial disease (PAD). (medscape.com)
  • The ACE I/D polymorphism influences individual differences in severity of coronary artery disease and the D allele promotes generation of numerous and critical atherosclerotic lesions. (degruyter.com)
  • To assess the effects of PTCRA for coronary artery disease in patients with non-complex and complex lesions (e.g. ostial, long or diffuse lesions or those arising from in-stent re-stenosis) of the coronary arteries. (cochrane.org)
  • this phenomenon is termed stable angina and is associated with narrowing of the arteries of the heart. (wikipedia.org)
  • With advanced disease, the narrowing of coronary arteries reduces the supply of oxygen-rich blood flowing to the heart, which becomes more pronounced during strenuous activities during which the heart beats faster. (wikipedia.org)
  • Coronary artery disease is characterized by heart problems that result from atherosclerosis. (wikipedia.org)
  • EBTs are cutting-edge diagnostic tools that can detect tumors anywhere in the body and uncover hidden evidence of heart disease. (cnn.com)
  • Coronary calcium scan looks for calcium deposits in the coronary (heart) arteries. (healthgrades.com)
  • A coronary calcium scan uses medication to slow your heart and an EKG machine to record your heart's electrical activity during the scan. (healthgrades.com)
  • A blocked coronary artery can result in a heart attack. (medtronic.com)
  • Coronary artery disease (CAD) is a heart disease that causes an inadequate supply of blood to the heart muscle - a potentially damaging condition. (medtronic.com)
  • Coronary artery disease is also referred to as coronary heart disease (CHD). (medtronic.com)
  • Approximately 2.3 million people in the UK have coronary heart disease. (medtronic.com)
  • These deposits slowly narrow the coronary arteries, causing your heart to receive less blood and oxygen. (medtronic.com)
  • If your doctor suspects you have coronary artery disease, he or she can refer you to a cardiologist that specialises in problems of the heart, arteries and veins. (medtronic.com)
  • Heart disease is the No. 1 cause of death in the U.S., with one person dying from the condition every 34 seconds. (activistpost.com)
  • Not only does working out at high intensity lead to powerful health gains, even in older adults and those with heart disease, but it does so in a fraction of the time compared to moderate- or low-intensity workouts. (activistpost.com)
  • Vascular function is also critical for cardiovascular health, and HIIT is beneficial for this as well, even in people with metabolic disorders and heart disease. (activistpost.com)
  • Not only does it protect against heart disease, but it has also been linked with a lower likelihood of diabetes, certain cancers, and other health problems. (worldhealth.net)
  • Although recent progress in cardiovascular medicine has introduced major scientific and technological breakthroughs, heart disease has been the second cause of death in Japan and the leading cause of death in the entire world. (juntendo.ac.jp)
  • the latest research from Tulane University suggests that taking as few as 50 steps and climbing stairs each day can significantly lower the risk of heart disease. (helsinkitimes.fi)
  • The study not only highlights the efficacy of daily stair climbing but also suggests that even those at higher risk of heart disease can offset this risk through regular stair climbing. (helsinkitimes.fi)
  • MALAGA, Spain -- Grey hair has been linked with an increased risk of heart disease in men, in research presented today at EuroPrevent 2017. (sunstar.com.ph)
  • The 2019 ACC/American Heart Association Guideline on the Primary Prevention of Cardiovascular Disease recommends a diet that emphasizes the intake of vegetables, fruits, legumes, whole grains and fish to decrease heart disease risk factors. (scienceblog.com)
  • Participants were given a food frequency questionnaire for dietary assessments to evaluate dietary behaviors and evaluate the association between whole grain and refined grain intake and the risk of PCAD in individuals without a prior diagnoses of heart disease. (scienceblog.com)
  • Even worse than the huge number of people dying from coronary disease every year is that researchers have estimated that 80-90% of heart disease can be prevented (Kones R. 2011) (Mozaffarian D, et al. (athleteinme.com)
  • Sanchis-Gomar F, Perez-Quilis C, Leischik R, Lucia A. Epidemiology of coronary heart disease and acute coronary syndrome. (thrombosisadviser.com)
  • Recent human studies confirm a strong association between low magnesium levels and higher heart disease risk. (lifeextension.com)
  • This happens when a fluttering atrial chamber in the heart causes a clot (thrombus) to form that travels up a carotid artery and blocks blood flow to a portion of the brain. (lifeextension.com)
  • Atherosclerosis can affect the arteries of the brain, heart, kidneys, other vital organs, and the arms and legs. (health-care-articles.info)
  • when it develops in the arteries that supply the heart (coronary arteries), a heart attack may occur. (health-care-articles.info)
  • Arteries are blood vessels that carry oxygen-rich blood from the heart to other parts of the body. (health-care-articles.info)
  • This series of medical illustrations shows atherosclerotic coronary artery disease (atherosclerosis) of the heart. (smartimagebase.com)
  • Eighty million adults are affected by heart disease (one in three people) and twenty-five percent of deaths in the United States are due to heart disease. (naturemedclinic.com)
  • Coronary artery disease is a condition in which the blood supply to the heart muscle is partially or completely blocked. (msdmanuals.com)
  • This is based on The Framingham Heart Study, which was the first study to reveal a positive association between total cholesterol and coronary artery disease (CAD). (medscape.com)
  • Serum cholesterol, lipoproteins, and the risk of coronary heart disease. (medscape.com)
  • Libby P. Mechanisms of acute coronary syndromes and their implications for therapy. (thrombosisadviser.com)
  • Unstable Angina) Acute coronary syndromes result from a sudden blockage in a coronary artery. (msdmanuals.com)
  • Coronary artery disease is caused by a build-up of fatty, waxy deposits on the inside of your arteries. (medtronic.com)
  • [iii] Coronary atheroma volume refers to the amount of degeneration in artery walls due to accumulated fatty deposits and scar tissue. (activistpost.com)
  • Non-alcoholic fatty liver disease is marked by hepatic fat accumulation not due to alcohol abuse. (mdpi.com)
  • Atherosclerosis is a condition in which fatty material collects along the walls of arteries. (health-care-articles.info)
  • This fatty material thickens, hardens, and may eventually block the arteries. (health-care-articles.info)
  • It's the name of the process in which deposits of fatty substances, cholesterol, cellular waste products, calcium and other substances build up in the inner lining of an artery. (health-care-articles.info)
  • We have developed expertise in in vivo investigation of lipid and glucose metabolism, insulin secretion and sensitivity, and vascular biology and in human physiological studies, leading to discovery of attractive drug targets that have been either patented or being investigated for their utility in treatment of fatty liver disease and diabetes in 2 clinical trials in the outlier populations of Fars/Iran. (yale.edu)
  • One of our groundbreaking discoveries was the identification of founder mutations in the DYRK1B gene, underlying atherosclerosis, metabolic syndrome, and fatty liver disease. (yale.edu)
  • We are now fully characterizing this protein and evaluating its utility as a drug target for diabetes, dyslipidemia, and fatty liver disease. (yale.edu)
  • literally "hardening of the arteries," which involves fatty deposits in the artery walls and may progress to narrowing and even blockage of blood flow in the artery), occurs in about 2 to 9% (depending on sex and race) of people aged 20 and older. (msdmanuals.com)
  • Recently, numerous studies have shown that the fibrinogen-to-albumin ratio (FAR) does not only have a high prognostic value in certain types of cancer including gastric, colorectal, and gallbladder cancer [ 8 - 10 ] but also have an association with the presence and poor clinical outcome of cardiovascular disease [ 11 - 14 ]. (hindawi.com)
  • However, none has addressed the association between FAR and severity of coronary artery disease (CAD), clinical outcome in NSTE-ACS patients firstly implanted with drug-eluting stent (DES). (hindawi.com)
  • Family physicians need to identify and mitigate risk factors early, as well as recognize and respond to acute coronary syndrome events quickly in any clinical setting. (aafp.org)
  • Stent induced hemodynamic changes in the coronary arteries are associated with higher risk of adverse clinical outcome. (researchgate.net)
  • A widely cited study published in the journal Radiology in 2003 found a high correlation between "the extent of coronary calcium"--that's the calcium score--and "mortality risk. (cnn.com)
  • Symptomatic peripheral artery disease (PAD) as evidenced by either intermittent claudication, previous revascularization, or amputation due to atherosclerotic disease at any time prior to randomization. (who.int)
  • Climbing more than five flights of stairs daily is associated with a reduced risk of atherosclerotic cardiovascular disease (ASCVD) of about 20%, new observational data suggest. (medscape.com)
  • The frequencies of DD genotype, D allele carrier-state ( DD+ID genotypes) and the D allele increased with the number of stenoses in coronary vessels. (degruyter.com)
  • D allele carriers ( DD+ID genotypes) were more frequent in the subgroup of patients with stenoses in at least four coronary vessels than in other patients including subjects with one-, two- and three-vessel disease (97.4% vs. 74.4%, OR=13.05, 95% CI: 1.81-100.00, χ 2 =9.84, p=0.0017). (degruyter.com)
  • Peripheral artery disease (PAD) is a condition of the blood vessels that supply the legs and feet. (medlineplus.gov)
  • In this study, we sought to evaluate the relationship between FAR and severity of CAD, long-term prognosis in non-ST elevation acute coronary syndrome (NSTE-ACS) patients firstly implanted with drug-eluting stent (DES). (hindawi.com)
  • The host response to this infection is an important factor in determining the extent and severity of the disease. (medscape.com)
  • Smoking is associated with increased risk of cardiovascular events, disease severity, and mortality among patients hospitalized for SARS-CoV-2 infections. (ucsd.edu)
  • 22 Thickening of the carotid artery indicates progression of atherosclerosis. (lifeextension.com)
  • The in vivo neointimal hyperplasia model was established 2 weeks after the carotid artery balloon injury in SHR rats. (hindawi.com)
  • article{31eec8df-8a41-4279-ab4d-15281485e454, abstract = {{Background: Traditional risk factors for atherosclerotic disease (AD) are well-known, of which some are relevant also for abdominal aortic aneurysms (AAA). (lu.se)
  • However, this calculator has been criticized for overestimating the risk of cardiovascular disease in adults without diabetes. (aafp.org)
  • Over time, however, too much pressure in your arteries can make the walls thick and stiff sometimes restricting blood flow to your organs and tissues. (health-care-articles.info)
  • The walls of the arteries also become stiffer and cannot widen (dilate) to allow greater blood flow when needed. (medlineplus.gov)
  • The ε4 allele has been associated with a higher risk of cardiovascular disease and AD, while the ε2 allele has a protective effect against AD. (spandidos-publications.com)
  • The findings unveiled that daily stair climbing significantly lowered the risk of cardiovascular disease, especially for those who were deemed less susceptible. (helsinkitimes.fi)
  • 10 , 11 Dyslipidemia in ESRD patients is characterized by a dysregulation of the synthesis and activity of HDL, leading to decreased plasma levels of HDL cholesterol (HDL-C). 10 Many epidemiologic studies have documented an inverse relationship between HDL-C levels and the progression of atherosclerosis and increased risk of cardiovascular disease in the general population. (lww.com)
  • Despite of the use of current guideline-recommended therapies, including prompt coronary revascularization, dual antiplatelet therapy, and intensive lipid-lowering therapy, ACS patients still have a poor prognosis [ 1 - 3 ]. (hindawi.com)
  • Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient partitioning. (nature.com)
  • Recently, it has been recognized dren and Adolescents9, recommending that changes in the serum lipid levels in changes in the desirable values of lipi- childhood may be predictive of the oc- ds, with reductions in the total choleste- currence of cardiovascular disease in rol and LDL-C values and increase in the adults. (bvsalud.org)
  • Therefore, this study is aimed at Moreover, the persistence of an unfavo- contributing to this aspect and verifying rable lipid profile increases the risk of the occurrence of changes in the lipid coronary events, which explains the im- profile since preschool age, as well as portance of adopting preventive measu- associated factors in overweight children res early in childhood2,3. (bvsalud.org)
  • In this prospective, randomized, controlled trial, 42 men with angiographically proven coronary artery disease (cad) were randomized to control (n = 21) and yoga intervention group (n = 21) and were followed for one year. (qigonginstitute.org)
  • The left coronary artery (typically called the left main coronary artery) branches into the circumflex and the left anterior descending artery. (msdmanuals.com)
  • The National Center for Health Statistics (NCHS) is part of the Centers for Disease Control and Prevention (CDC) and is responsible for the collection and analysis of mortality data in the United States. (medscape.com)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • Furthermore, inactivating variants in ANGPTL4 are associated with reduced risk of coronary artery disease in humans, suggesting that ANGPTL4 and related LPL modulators may be targets for modification of dyslipidemia-related atherosclerotic cardiovascular disease 8 , 9 . (nature.com)
  • Cause of death was coded according to the International Classification of Diseases, 5th Revision (ICD-5) ( 6 ). (cdc.gov)
  • For both men and women, coronary disease is a major cause of death in the UK. (medtronic.com)
  • The medical examiner's report listed the cause of death as atherosclerotic coronary artery disease. (cdc.gov)
  • However, cardiovascular disease still takes the lives of more than 2,150 Americans each day, an average of one death every 40 seconds, and is still the number one cause of death. (naturemedclinic.com)
  • In high-income countries, coronary artery disease is the leading cause of death in both men and women, accounting for about one third of all deaths. (msdmanuals.com)
  • Simultaneously, blood stasis, endothelial damage, and hypercoagulability were also considered risk factors for acute coronary thrombotic events [ 7 ]. (hindawi.com)
  • A systematic review and meta-analysis involving 36 studies and 1,437 participants revealed that HIIT increased flow-mediated dilation (FMD) - a measure of endothelial function - in people with cardiometabolic diseases, while moderate-intensity continuous training (MICT) or no exercise did not. (activistpost.com)
  • Atherosclerosis and Alzheimer's disease (AD) are a major cause of morbidity and mortality in Western societies. (spandidos-publications.com)
  • Atherosclerosis is considered to be a risk factor for cognitive deterioration in the elderly, including Alzheimer's disease (AD) ( 3 , 4 ). (spandidos-publications.com)
  • Title: Apolipoprotein D modulates amyloid pathology in APP/PS1 Alzheimer's disease mice. (genscript.com)
  • Variations in ApoE are also associated with altered odds of having Alzheimer's disease and other diseases. (feedburner.com)
  • The study recruited 2099 individuals with PCAD from hospitals with catheterization labs in different cities and ethnicities throughout Iran who underwent coronary angiography (women aged ≤ 70 and men ≤ 60). (scienceblog.com)
  • This refers to the atherosclerotic narrowing of the coronary arteries in men under 55 and women under 65. (worldhealth.net)