Atherosclerosis saphenous vein. Medical search. Frequent questions

Coronary artery revascularization with saphenous vein grafts (SVGs) has become a surgical standard for treatment of coronary artery disease since Favaloro first described it in 1967. (medscape.com)
In medicine, vein graft failure (VGF) is a condition in which vein grafts, which are used as alternative conduits in bypass surgeries (e.g. (wikipedia.org)
Having an intact outer fat pedicle is what differentiates the two main techniques for harvesting saphenous vein grafts. (wikipedia.org)
The solutions in which vein grafts are stored after harvesting also play an important role. (wikipedia.org)
Despite advances in surgical technique and optimised pharmacological treatment, approximately 50% of all saphenous vein grafts (SVGs) fail at 10 years following coronary implantation often requiring potentially life-threatening and costly re-interventions. (gla.ac.uk)
Thus, even though total arterial revascularization is preferable, the patient population has become older and emergency situations are still frequent so that the need to use vein grafts remains high [ 3 ]. (biomedcentral.com)
Vein grafts need a proximal anastomosis which is usually performed on the ascending aorta. (biomedcentral.com)
Autologous saphenous vein grafts are the most common bypass grafts for treating peripheral artery diseases. (clemson.edu)
Perfusion bioreactors have allowed researchers to study vein grafts ex-vivo, creating a better understanding of vein remodeling. (clemson.edu)
Tissue was obtained from coronary arteries without prior instrumentation (primary lesions, n = 31), aortocoronary saphenous vein bypass grafts with primary lesions (n = 8), coronary arteries with lesions developing after prior balloon angioplasty or mechanical atherectomy (reste-notic lesions, n = 30) and vein bypass grafts with restenotic lesions (n = 4). (elsevierpure.com)
These lesions frequently contained cholesterol crystals (45% of coronary arteries, 50% of vein grafts) and calcium deposits (65% of coronary arteries, 38% of vein grafts). (elsevierpure.com)
If left untreated, about half of bypass vein grafts become occluded within 10 years of surgery. (pleasecritiqueme.com)
She underwent bilateral upper extremity bypasses using saphenous vein grafts. (lvhn.org)
We hypothesized that short-term treatment with atorvastatin before CABG would improve the redox state in saphenous vein grafts (SVGs), independently of low-density lipoprotein cholesterol (LDL)-lowering. (ox.ac.uk)
With regard to conduit type, vein grafts are superior to all prosthetic conduits for infrapopliteal bypass, regardless of target vessel. (medscape.com)
[ 5 ] and spliced vein grafts from the arm can also be used. (medscape.com)
[ 3 ] The 1-year patency rates of vein conduit in the infrapopliteal position reach 70-80%, whereas those of prosthetic grafts reach 30-50% at best. (medscape.com)

To analyse atherosclerotic plaques of the carotid artery, samples of apparently healthy greater saphenous veins and circulating leucocytes from the same individual patients for the presence of Helicobacter pylori and Mycoplasma pneumoniae . (bmj.com)
Reijnen and colleagues treated 104 greater saphenous veins in 85 patients at two participating centres. (vascularnews.com)

Differences in duration of anticoagulation after pulmonary embolism and deep vein thrombosis: Findings from the SWIss Venous ThromboEmbolism Registry (SWIVTER). (uzh.ch)
Outcome after bilateral deep vein thrombosis. (uzh.ch)

In-stent restenosis and atherosclerosis in a human saphenous vein graft. (ox.ac.uk)

Veins, mainly the great saphenous vein (GSV) are the most frequently used conduits in bypass surgeries (CABG or PABG), due to their ease of use and availability. (wikipedia.org)
25 April 2018 - Publisher: Journal of the American Medical Association RCT (n=500) showed among patients undergoing elective CABG with saphenous vein grafting, ticagrelor + aspirin significantly increased graft patency rate after … Altogether, 114 papers were found from Medline and 59 papers were found from the Cochrane Central Register of Controlled Trials using the reported search, of which seven presented the best evidence to answer the clinical question. (pleasecritiqueme.com)
Preoperative atorvastatin treatment in CABG patients rapidly improves vein graft redox state by inhibition of Rac1 and NADPH-oxidase activity. (ox.ac.uk)
BACKGROUND: Statins improve clinical outcome of patients with atherosclerosis, but their perioperative role in patients undergoing coronary artery bypass grafting (CABG) is unclear. (ox.ac.uk)

This technique shown to improve vein graft patency and less development of intimal hyperplasia. (wikipedia.org)
Results of the Clopidogrel After Surgery for Coronary Artery Disease (CASCADE) trial confirmed that this practice independently associated with improved graft patency, as demonstrated by coronary angiography and saphenous vein graft intravascular ultrasonography. (medscape.com)

Aetiologies include atherosclerosis as well as rheumatologic diseases. (lvhn.org)

After 5 years the patency rate drops to 65% and at 10 years GSV patency rates are approximately 50%, with only half of the veins are atherosclerosis free. (wikipedia.org)

Image courtesy of Rustempasic N, Cvorak A, Agincic A. Outcome of endovenous laser ablation of varicose veins. (medscape.com)
Much about the etiology of varicose veins remains unknown. (medscape.com)
Although few studies document the natural history of varicose veins (shown) , superficial venous insufficiency is considered to be progressive over time, typically beginning as reticular veins or corona phlebectatica ("corona"), developing into isolated calf varicosities and, eventually, resulting in a tortuous and distended great saphenous vein. (medscape.com)
In recent years, there was a substantial progress with regard to laser techniques and systems in the treatment of varicose veins of lower extremities. (klinikaflebologii.pl)
Compared to elder laser systems, using shorter wavelengths, e.g. 810 or 980 nm, innovative systems made laser therapy of varicose veins to be the most effective, universal and exceptionally safe for patient. (klinikaflebologii.pl)
Laser therapy of varicose veins is the most popular method out of all minimally invasive methods of varicose vein treatment. (klinikaflebologii.pl)
In the Clinic of Phlebology in Warsaw, laser therapy of varicose veins is performed using laser system of the newest generation by Biolitec (ELVeS 1470 nm). (klinikaflebologii.pl)
In the Clinic of Phlebology, thanks to the multidiscipline team we use very often hybrid procedures (combined), consisting in adopting several types of methods allowing for effective treatment of leg varicose veins. (klinikaflebologii.pl)
Besides the fact that the potential of modern laser systems is very high, there are situations in which the effective treatment of varicose veins of lower extremities by means of endovenous laser is hindered or impossible. (klinikaflebologii.pl)
In the Clinic of Phlebology, thus, the decision on the selection of adequate method of treatment of varicose veins is always preceded by the precise Doppler ultrasound of veins of lower extremities. (klinikaflebologii.pl)

The most common site for saphenous vein graft aneurysm (SVGA) formation appears to be the right coronary artery (38.0%), followed by the left anterior descending (25.3%), obtuse marginal (10.9%), and left circumflex (10.5%), according to a systematic review of published cases by Ramirez et al. (medscape.com)

M pneumoniae -specific DNA was detected in the atherosclerotic plaques of 13 of 36 (36.1%) patients, in the saphenous veins of 9 of 36 (25%) patients and in the leucocytes of 27 of 36 (75%) patients. (bmj.com)
No salient association was observed between the presence of M pneumoniae -specific DNA in leucocytes and atherosclerotic plaques or veins. (bmj.com)
Vein graft atherosclerotic lesions are more diffuse and concentric, yet less calcified, compared to native atherosclerotic lesions, and are more susceptible to thrombosis formation and rupture. (wikipedia.org)
Atherosclerosis Atherosclerosis is a condition in which patchy deposits of fatty material (atheromas or atherosclerotic plaques) develop in the walls of medium-sized and large arteries, leading to reduced or. (msdmanuals.com)

The cardiac veins collect blood containing waste products from the heart muscle and empty it into a large vein on the back surface of the heart called the coronary sinus, which returns the blood to the right atrium. (msdmanuals.com)
The treatment goals for patients with coronary artery atherosclerosis are to relieve symptoms of coronary artery disease (CAD) and to prevent future cardiac events, such as unstable angina, AMI, and death. (medscape.com)
Nevertheless, prevention of cardiac events is likely to have the largest impact on decreasing the burden of atherosclerosis. (medscape.com)

The absence of H pylori and the random distribution of M pneumoniae in tissue samples obtained from patients with symptomatic carotid artery stenosis do not support a role for these pathogens in the development of atherosclerosis due to a direct interaction of the bacteria with the vasculature. (bmj.com)
In the case of ascending aortic disease and saphenous vein grafting, the Slit Device avoids aortic clamping thereby preventing atheroembolism and also avoiding the need for hypothermic circulatory arrest in patients with unclampable aorta. (biomedcentral.com)
Nevertheless, for many reasons, saphenous vein grafting is still the norm and is a widespread technique in elderly patients or in emergency situations. (biomedcentral.com)
Association of the ACE rs4646994 and rs4341 polymorphisms with the progression of carotid atherosclerosis in slovenian patients with type 2 diabetes mellitus. (cdc.gov)
Association of Angiotensin-Converting Enzyme Genotype, Insertion/Deletion Polymorphism and Saphenous Vein Graft Atherosclerosis in Iranian Patients. (cdc.gov)
BACKGROUND: Thirty-eight patients with intermediate (30%-60% diameter stenosis) saphenous vein graft lesions were randomized to extended-release niacin (ER-niacin) or placebo for 12 months. (elsevierpure.com)
Reticular veins are typically small (1-3 mm), highly visible, and often pose a cosmetic problem for patients. (medscape.com)
Large, multicenter randomized trials of various pharmacologic modalities have recently achieved great success in the treatment of patients with coronary artery atherosclerosis. (medscape.com)

In conclusion, MOCA is proven to be effective and safe for treating greater saphenous vein insufficiency," Reijnen said. (vascularnews.com)

Partially reversible lung consolidation after revascularization of a total occlusion of both left pulmonary veins following ablation of atrial fibrillation: a case report. (uzh.ch)

Primary lesions were characterized by dense intimai fibrosis with necrotic debris (83% of intimai tissue) and foam cells typical of atherosclerosis. (elsevierpure.com)
Restenotic lesions were characterized by an increased proportion of loose fibroproliferative tissue (45% of coronary artery intima, 35% of vein graft intima). (elsevierpure.com)
Atherosclerosis (also known as arteriosclerotic vascular disease) is a chronic inflammatory disease of the arterial wall, characterized by the formation of lipid-laden lesions. (shengsci.com)

ICD-10-CM Code for Atherosclerosis of coronary artery bypass graft(s) without angina pectoris I25. (locke-movie.com)

In more than 50% of the general population, superficial venous disease appears in the form of "spider" or reticular veins, but in approximately 20%-25% of the population, the disease can progress to visible varicosities at its extremes, such as ulceration or skin changes. (medscape.com)

Atherosclerosis in peripheral arteries is a major contributing factor. (clemson.edu)

Nonetheless, it is important to diagnose PAD because it is a marker of systemic atherosclerosis with excess cardiovascular risk, and it may identify a patient who may develop progressive disability and risk of limb loss. (nih.gov)

Although, EVH has been associated with higher risk of vein graft stenosis and occlusion. (wikipedia.org)

The procedure itself consists in the insertion of special optical fibre to the lumen of affected vein and then its occlusion. (klinikaflebologii.pl)

In cases of vein-to-aorta proximal anastomosis it is obtained by a partial occluding, side-biting clamp on the aortic wall (Figure 1 ). (biomedcentral.com)

Riahi and associates described the rare complication of saphenous vein graft aneurysm (SVGA) in 1975. (medscape.com)
The mechanism responsible for the formation of saphenous vein graft aneurysm (SVGA) is poorly understood. (medscape.com)

The great saphenous vein of the leg remains the most used conduit for all non-left anterior descending (LAD) territories. (gla.ac.uk)
The most durable and effective revascularization procedure for PAD in diabetes is surgical bypass with saphenous vein as the conduit. (nih.gov)
The bypass conduit should usually be composed of autogenous vein, but prosthetic material can be used in the absence of suitable autogenous conduit. (medscape.com)

Gene therapy is another strategy that been suggested to prevent VGF as the veins are ideally suited for ex vivo treatment prior to grafting. (wikipedia.org)
The goals of therapy should include arresting atherosclerosis or even reversing its progression. (medscape.com)

A diagnostic procedure in which a catheter is placed in a large vein in the leg or arm and advanced to the heart to check for blood pressure within the heart, oxygen in the blood, and/or pumping ability of the heart muscle. (buffalovascularcare.com)

The Alu polymorphism of angiotensin I converting enzyme (ACE) and atherosclerosis, incident chronic diseases and mortality in an elderly Chinese population. (cdc.gov)
Criteria to predict mid-term outcome after stenting of chronic iliac vein obstructions (PROMISE trial). (uzh.ch)

Some structural changes of intima thickening and vein wall remodeling are necessary for vein graft adaptation to the arterial environment. (wikipedia.org)

Blood may flow directly from the artery to the vein, bypassing the small vessels where oxygen and tissue nutrients are exchanged. (buffalovascularcare.com)

Over time continued SMC migration and proliferation cause extracellular matrix deposition and fibrotic change that lead to development of intimal hyperplasia, which results in luminal loss that makes the graft more susceptible to atherosclerosis. (wikipedia.org)
Providing the vein with external support prior to grafting has shown to reduce intimal hyperplasia formation and improve the hemodynamics within the graft. (wikipedia.org)
A combination of mechanical damage and sclerotherapy, MOCA uses a rotating wire to cause cellular damage to the intimal layer of the vein and result in spasm. (vascularnews.com)

Pathogenic drivers of SVG disease include early thrombosis, neointima formation (NF) and accelerated atherosclerosis. (gla.ac.uk)
In addition, venous injuries can occur such as subclavian vein thrombosis. (sicot-j.org)

Probably because of the shift toward improved cosmetic outcome and patient satisfaction provided by endoscopic vein harvesting (EVH). (wikipedia.org)

That infections with certain pathogens, by initiating an inflammatory response, may contribute to the development of atherosclerosis is suggested by clinical and experimental evidence. (bmj.com)

The mean diameter of the treated veins was 5.2mm (range 3.5-12.8mm) and the length of treated segment was 45cm (range 20-62cm). (vascularnews.com)

Code 33510 describes a single vessel bypass using a vein. (locke-movie.com)
Such approach provides us with the possibility of precise deactivation of the incompetent vessel from circulation with simultaneous maintenance of functioning of other normally working veins. (klinikaflebologii.pl)

Valve insertion points along the vein graft are especially prone to true SVGA formation, where smooth muscle in the media changes from circular to a weaker longitudinal orientation. (medscape.com)

The No-touch technique is where the vein is harvested with the surrounding tissues, keeping the vasa vasorum and the nerves in the adventitia intact. (wikipedia.org)

Side clamping to perform saphenous vein-to-aorta proximal anastomosis is a well known cause of cerebral embolization during coronary bypass surgery. (biomedcentral.com)
[ 2 ] If a prosthetic graft is used in the infrapopliteal position, an adjunctive vein cuff at the distal anastomosis improves patency. (medscape.com)

This cascade of events is exacerbated by arterial pressures within the vein graft. (medscape.com)
The grafting exposes the vein to arterial pressure and flow that causes increased shear stress and wall tension, which further damages the endothelial layer and SMC. (wikipedia.org)

RAGE has been extensively implicated in inflammatory states such as atherosclerosis, but the role of S100A12 as its ligand is less clear. (keyopinionleaders.com)

Progressive atherosclerosis is the primarily cause of late vein graft failure. (wikipedia.org)

Within the veins, a system of valves helps overcome the pull of gravity and maintains a unidirectional flow of blood (shown) . (medscape.com)

Studies in small and large animal models have shown that TGF-b1 is up-regulated following vein grafting. (gla.ac.uk)

Anatomy56

Organisms5

Diseases45

Chemicals and Drugs36

Analytical, Diagnostic and Therapeutic Techniques and Equipment51

Phenomena and Processes16

Disciplines and Occupations1

Technology, Industry, Agriculture1

Information Science1

Health Care12

Geographicals1

Grafts17

Greater saphenous veins2

Deep Vein Throm2

Human saphenous1

CABG4

Graft patency2

Include atherosclerosis1

Patency rates1

Varicose10

Right corona1

Atherosclerotic4

Cardiac3

Patients8

Insufficiency1

Atrial fibrillation1

Lesions3

Angina pectoris1

Reticular veins1

Peripheral arteries1

CARDIOVASCULAR1

Stenosis1

Occlusion1

Aortic1

Aneurysm2

Conduit3

Therapy2

Large vein1

Chronic2

Intima1

Vessels1

Intimal3

Thrombosis2

Outcome1

Clinical1

Diameter1

Vessel2

Insertion1

Vasa1

Anastomosis2

Arterial2

Inflammatory1

Primarily1

Valves1

Small1