• There is evidence to believe that certain defects of any components of the elastic matrix may impair and alter the structural appearance of elastic and collagen fibers. (wikipedia.org)
  • Is elastin a collagen? (clevelandclinic.org)
  • No, elastin isn't a collagen . (clevelandclinic.org)
  • However, elastin and collagen are both proteins that often get confused with each other. (clevelandclinic.org)
  • Structural and elastic properties of major arteries are mostly imparted by the media, which is composed of smooth muscle cells surrounded by elastin, collagen, and proteoglycans. (amfs.com)
  • Finally, students learn about collagen, elastin and proteoglycans and their roles in giving body tissues their unique functions. (teachengineering.org)
  • A transition point was defined as the pressure at which the pressure-area relation deviated from its elastic (linear) to the collagen (exponential) course. (bmj.com)
  • In six patients (five with and one without β blockade), a transition point in the pressure-area curve was observed, indicating that the load bearing component was not only elastin but also collagen. (bmj.com)
  • When, in addition to elastic fibres, collagen fibres are recruited, the pressure-area curve shows a transition from elastic (linear) to a stiff (exponential) course. (bmj.com)
  • The medial layer of the aorta consisting of elastin, collagen, and smooth muscle cells, ensures the elasticity and tensile strength of the aortic wall. (escardio.org)
  • Tissues that expand, such as blood vessels and lungs, need to be both strong and elastic, so they contain both collagen and elastin. (nih.gov)
  • These arteries have several collagen and elastin filaments to stretch by a single pulse of a heart. (rightquotes4all.com)
  • Dermology immensely helps skin to stay healthy and firm, greatly increases the production of collagen and elastin within the epidermis and increases the elasticity of the skin, which helps individuals to fully have elastic skin which helps prevent the ongoing growth of stretch marks. (naturalenhancementsreviews.com)
  • o Cross linking theory promises that cross linking (which occurs in proteins, DNA, and lipids from publicity to environmental and dietary compounds) actually modifications the attributes of the tissues of entire body organs, such as collagen and elastin, which then turn out to be considerably less pliable and considerably less elastic, ensuing in gross improvements in the pores and skin, artery walls, the musculoskeletal system, and the lens of the eye. (azitropharma.com)
  • It contains all three types of fibers (collagen, elastic, and reticular), which are distributed randomly and crisscross in all directions, as shown in Figure 1. (github.io)
  • These are water-insoluble animal proteins, e.g. collagen (major protein of connective tissues), elastins (protein of arteries and elastic tissues) and keratins (proteins of hair, wool and nails) are good examples of fibrous proteins. (topperlearning.com)
  • The research team separated the aortic tissue into two types of proteins, collagen and elastin. (washington.edu)
  • Fibrous collagen is widespread in biological tissues, while elastin has only been found in animals with a backbone. (washington.edu)
  • Heart attack and stroke sometimes happen when the atheroma 'bursts' - the fibrous cap (of smooth muscles cells, cholesterol-rich foam cells, collagen and elastin) which surrounds the atheroma is ruptured, or breaks free from the arterial wall, causing a blood clot (thrombus). (ussromantics.com)
  • This layer is surrounded by the tunica intima (sometimes the epithelium is described as part of the T intima), an elastic layer quite rich in collagen. (ussromantics.com)
  • Elastic fibers are composed of elastin molecules and can be found together with collagen fibers in tissues that require elasticity in addition to tensile strength, e.g., the lung . (amboss.com)
  • The skin has particularly high compositions of two connective tissue proteins called elastin and collagen. (nasobih.com)
  • . Grape seed extract has been found to be especially helpful in protecting connective tissue against the effects of sun damage as the grape seed extract has an affinity for the collagen and elastin in connective tissue and helps to maintain their normal biochemical structures. (nasobih.com)
  • Additionally, collagen and elastin, two proteins that keep your skin both firm and elastic, are significantly reduced by smoking. (disruptedphysician.com)
  • It is mainly determined by components of the arterial wall, such as elastin, collagen, and vascular smooth muscle tone, among others. (cardiex.com)
  • This collagen type supports the structure of muscles, organs, and arteries. (mdhair.co)
  • 12, 13 This transition point is a denominator of aortic elastic behaviour in the normal blood pressure range, and is of additional importance in relation to the forces the aorta can withstand before rupturing. (bmj.com)
  • The normal ascending aorta functions as an elastic reservoir to enhance arterial flow. (escardio.org)
  • The ascending part of the aorta is more elastic than the descending part due to its greater concentration of elastic fibres. (escardio.org)
  • Whereas other aneurysms of the aorta are associated with atherosclerosis, aneurysms of the ascending aorta are mostly associated with degenerative changes in elastic media. (escardio.org)
  • Degenerative processes in ascending aorta - cystic medial degeneration - affect the medial layer by varying degrees of elastic fibre fragmentation and smooth muscle loss. (escardio.org)
  • Although fragmentation of elastic fibre is a normal process of aging, it may occasionally accelerate and cause partial or complete loss of elastic fibres and smooth muscle cells in the medial layer of the aorta. (escardio.org)
  • The aorta in Marfan's syndrome exhibits the typical features of cystic medial degeneration with disruption of elastic fibres and fibrosis of media. (escardio.org)
  • The majority of Dr. Kozel's work focuses on the study of two elastin insufficiency-related diseases: the neurodevelopmental condition known as Williams syndrome (WS) and isolated supravalvular aortic stenosis (SVAS), a narrowing of the aorta, the vessel that carries blood from the heart to the rest of the body. (nih.gov)
  • In fact, the major artery of your body, the aorta, lies just in front of the vertebral column. (yogauonline.com)
  • Every time you bring your back into extension, the aorta, and the heart itself, are under gentle tension that can keep the smooth muscle and cardiac muscle supple and elastic. (yogauonline.com)
  • The arteries receive blood directly from the heart, e.g. the aorta and pulmonary artery. (rightquotes4all.com)
  • A] Elastin stain (black) showing damaged elastic lamina in aorta. (nih.gov)
  • Inset (higher magnification) shows fluorescent nanoparticles attached to aorta where elastin is damaged. (nih.gov)
  • B] Elastin stain showing aorta with undamaged elastic lamina. (nih.gov)
  • It pumps blood directly into arteries, more specifically the aorta or the pulmonary artery. (physio-pedia.com)
  • The largest artery is the aorta, which extends from the left ventricle down the left side of the body. (physio-pedia.com)
  • For example, they include the pulmonary artery and the aorta. (veininstitutenj.com)
  • The aorta is the main artery carrying blood away from the heart. (veininstitutenj.com)
  • 50% of the dry weight of the normal aorta is elastin. (unboundmedicine.com)
  • Smokers are also at risk for diseases of the blood vessels such as the carotid artery and aorta. (healthjockey.com)
  • An aortic aneurysm is a weak spot in the aorta - the main artery that carries oxygen-rich blood from the heart to the rest of the body. (nih.gov)
  • That's because as the aortic pressure pulse (the difference between the systolic and diastolic pressures) travels down the aorta into other arteries (which distribute the blood to other parts of the body), characteristic changes occur in both the systolic and diastolic pressures, as well as in the mean pressure. (cardiex.com)
  • This occurs because of reflective waves when the blood branches off into the other arteries and because of increased blood vessel stiffness as the pressure pulse moves away from the aorta into the other arteries. (cardiex.com)
  • Giant cell arteritis Giant Cell Arteritis Giant cell arteritis (GCA), also known as temporal arteritis, is a type of large-vessel vasculitis that predominantly affects the aorta and its major branches, with a predilection for the branches of the carotid (including the temporal artery). (lecturio.com)
  • Coarctation of aorta Aorta The main trunk of the systemic arteries. (lecturio.com)
  • Elastosis is the buildup of elastic fibers in tissues, and is a form of degenerative disease. (wikipedia.org)
  • Elastin helps tissues and organs in your body stretch. (clevelandclinic.org)
  • Your lungs create potential energy as they contract, and the elastic tissues in your lungs store that potential energy. (clevelandclinic.org)
  • The tunica intima, the innermost layer, consists of an inner surface of smooth endothelium covered by a surface of elastic tissues. (onteenstoday.com)
  • Describe the importance of elastin in human tissues and give an example of a tissue that uses elastin to function correctly. (teachengineering.org)
  • As its name implies, elastin is an elastic protein - it helps blood vessels as well as other tissues in the body stretch and recoil. (nih.gov)
  • Arteries are responsible for delivering oxygenated blood from the heart to tissues. (yogauonline.com)
  • Arteries are the blood vessels responsible for carrying oxygen-rich blood away from the heart to the body tissues. (rightquotes4all.com)
  • Arteries are tube-like and have smooth tissues. (rightquotes4all.com)
  • The layer of connective tissues anchors the artery in nearby other arteries. (rightquotes4all.com)
  • Arteries transport blood away from the heart to the tissues of the body. (rightquotes4all.com)
  • Arteries carry oxygen-rich blood from your heart to your tissues and organs. (veininstitutenj.com)
  • The systemic vessels are arteries that carry oxygen-rich blood from the heart's left ventricle to the tissues in all parts of the body. (veininstitutenj.com)
  • Elastin is a protein found in many tissues that allow flexibility, including elastic arteries. (veininstitutenj.com)
  • Pseudoxanthoma Elasticum (PXE) is a rare genetic disease caused by a mutation of the ABCC6 gene, resulting in calcification of elastic fibers of the skin, eye and other organs and tissues that contain elastin. (mssm.edu)
  • Only recently discovered in animal tissues, researchers have traced this property to elastin and found that when exposed to sugar, the elastin protein sometimes slows or stops its ferroelectric switching. (washington.edu)
  • This could lead to the hardening of those tissues and, ultimately, degrade an artery or ligament. (washington.edu)
  • The research team has focused solely on the aortic tissues, but this finding likely applies to other biological tissues that have the protein elastin, such as the lungs and skin. (washington.edu)
  • Fibrillin-1 is found in tissues that are rich in so-called elastic fibers, such as the skin, lungs, ligaments, and blood vessel walls. (nih.gov)
  • Like spandex fibers woven into clothing, elastic fibers let these tissues stretch without tearing. (nih.gov)
  • The mutant mice created by Ramirez and colleagues had sharply reduced levels of fibrillin-1 microfibrils, which the researchers predicted would impair formation of the normal elastic fiber network in tissues such as skin and blood vessels. (nih.gov)
  • To their surprise, the researchers found that elastin-containing elastic fiber networks still formed in connective tissues from these mice, and that these fibers appeared normal when examined under a microscope. (nih.gov)
  • Elastic fibers (or yellow fibers) are an essential component of the extracellular matrix composed of bundles of proteins (elastin) which are produced by a number of different cell types including fibroblasts, endothelial, smooth muscle, and airway epithelial cells. (wikipedia.org)
  • Elastic fibers are formed via elastogenesis, a highly complex process involving several key proteins including fibulin-4, fibulin-5, latent transforming growth factor β binding protein 4, and microfibril associated protein 4. (wikipedia.org)
  • Maintenance of crosslinked elastin is carried out by a number of proteins including lysyl oxidase-like 1 protein. (wikipedia.org)
  • Mature elastic fibers consist of an amorphous elastin core surrounded by a glycosaminoglycans, heparan sulphate, and number of other proteins such as microfibrillar-associated glycoproteins, fibrillin, fibullin, and the elastin receptor. (wikipedia.org)
  • Many of the genes associated with autosomal dominant and autosomal recessive forms of cutis laxa are involved in the formation and function of elastic fibers, which are slender bundles of proteins that provide strength and flexibility to connective tissue throughout the body. (medlineplus.gov)
  • Other proteins involved in cutis laxa that have critical roles in the assembly of elastic fibers are produced from the EFEMP2 , FBLN5 , LTBP4 , and ATP6V0A2 genes. (medlineplus.gov)
  • Elastin is one of the most abundant proteins in your body. (clevelandclinic.org)
  • New research suggests that more sugar in the body could damage the elastic proteins that help us breathe and pump blood. (washington.edu)
  • Although Elastin is one of the most stable proteins known, with a half-life of approximately 74 years, Elastin production ceases and is no longer available in adulthood. (elastrin.com)
  • The elastin core is covered by a sheath of fibers (called microfibrils) made up of fibrillin-1 and other proteins. (nih.gov)
  • He predicts that a second fibrillin gene, fibrillin-2, or perhaps several genes, play an important role in elastic fiber development, and that fibrillin-1 is just one of several proteins that form the scaffolding for elastin in developing elastic fibers. (nih.gov)
  • Atherosclerosis may induce AAA formation by causing mechanical weakening of the aortic wall with loss of elastic recoil, along with degenerative ischemic changes, through obstruction of the vasa vasorum. (amfs.com)
  • Atherosclerotic processes in aortic media cause extensive disruption of elastic fibres and smooth muscle cells which may then be replaced by extracellular matrix and lipids. (escardio.org)
  • Hypertension and some congenital heart defects are associated with alterations in the great arteries, arteries, and arterioles with alterations in the elastic matrix. (wikipedia.org)
  • We conclude that CH amplifies the detrimental effects of CS on the pulmonary circulation by altering the mechanical properties of pulmonary arteries and enhancing the remodelling of pulmonary arterioles. (ersjournals.com)
  • These arteries and their branches, down to the arterioles, have the structural characteristics of most systemic arteries. (onteenstoday.com)
  • Medium-sized arteries get blood from elastic arteries and transport the blood in arterioles and capillaries. (rightquotes4all.com)
  • Arterioles are small arteries that transport blood into capillaries. (rightquotes4all.com)
  • Blood travels from the arteries to the arterioles and on to the capillaries, where gaseous exchange takes place. (physio-pedia.com)
  • Elastic fibers allow the skin to stretch, the lungs to expand and contract, and arteries to handle blood flowing through them at high pressure. (medlineplus.gov)
  • A shortage of these fibers weakens connective tissue in the skin, arteries, lungs, and other organs. (medlineplus.gov)
  • Elastin allows your lungs to work like an elastic bag. (clevelandclinic.org)
  • The elastin in your lungs breaks down, and you may have symptoms including shortness of breath, a cough, wheezing, fatigue and long-term mucus production. (clevelandclinic.org)
  • Vena Cava ➜ RA ➜ Tricuspid valve ➜ RV ➜ Pulmonary valve ➜ Pulmonary artery ➜ lungs ➜Pulmonary vein ➜ LA ➜ Mitral valve ➜ LV. (physio-pedia.com)
  • these carry deoxygenated blood to the lungs , and the umbilical artery, which carries deoxygenated blood from the foetus to the placenta. (physio-pedia.com)
  • The pulmonary vessels are arteries that transport oxygen-poor blood from the heart's right ventricle to the lungs. (veininstitutenj.com)
  • Moreover, they may have difficulty exchanging oxygen as their lungs tend to become less elastic. (healthjockey.com)
  • She along with her colleagues found that some patients seem to not have the elastin-specific cells in their lungs, even though they had smoked. (healthjockey.com)
  • Elastin, as its name suggests, is springy and helps the heart and lungs stretch and contract. (washington.edu)
  • Is there smooth muscle in artery walls? (onteenstoday.com)
  • Arteries have a great deal more smooth muscle within their walls than veins, thus their greater wall thickness. (onteenstoday.com)
  • Elastin , another fibrous protein in the ECM, is abundant in artery walls. (nih.gov)
  • As we age, the elastin in the walls of our arteries deteriorates and it is not replaced, leading to stiffening. (yogauonline.com)
  • Arteries have thick muscular walls. (rightquotes4all.com)
  • Some people develop clogged arteries as a result from a buildup of plaque on the inner walls of the arteries. (veininstitutenj.com)
  • Damaged elastin fibers weaken the skin and arterial walls. (elastrin.com)
  • Elastic fibers in the walls of large blood vessels enable them to bounce back after being stretched. (nih.gov)
  • The diameter of vessels is controlled by both the amount of elastic fibers present and the degree of squeezing from smooth muscle cells in the vessel walls. (nih.gov)
  • Cutis laxa and Williams syndrome have elastic matrix defects that have been directly associated with alterations in the elastin gene. (wikipedia.org)
  • A mutation in the elastin gene is typically responsible for cutis laxa. (clevelandclinic.org)
  • Indeed, researchers have identified individuals with hemizygosity limited to the gene for elastin, a structural protein found in large arteries and other elastic connective tissue, and have established that SV AS results from this deletion. (psychologicalscience.org)
  • Individuals with WS are missing one copy of 25-27 coding genes, including the elastin gene - usually there are two copies of each of these genes. (nih.gov)
  • With only one good copy of the elastin gene, persons with WS and SVAS make inadequate quantities of elastin, which predisposes them to stiff blood vessels that are prone to stenosis (or vessel narrowing), restricting blood flow. (nih.gov)
  • The variability of the clinical signs of WS suggests that other genes work with the elastin gene in determining disease severity. (nih.gov)
  • To investigate this, Dr. Kozel initially began her work by studying mice with less elastin and looking to find additional gene changes throughout the genome (modifiers) that were associated with blood pressure and blood vessel size differences. (nih.gov)
  • One group of modified mice received minoxidil in their drinking water from weaning until 3 months, a second group was treated for only the two weeks before elastin gene studies, and a third group had plain water instead. (nih.gov)
  • Gene studies revealed that minoxidil revs up not only elastin and elastic fiber genes but also more than 100 other genes related to blood vessel structure. (nih.gov)
  • Because calcified arteries can bleed, hemorrhage from various organs is a reported complication of PXE. (mssm.edu)
  • So, generally, our arteries carry oxygenated blood from the heart to other organs and regions of the body. (ussromantics.com)
  • This is the blood pressure that the target organs-kidneys, heart, brain, and arteries-are exposed to. (cardiex.com)
  • Stiffening of the arteries damages the capillaries that nourish your organs, which means organ damage is very possible. (cardiex.com)
  • Atherosclerosis is a disease where plaque builds up inside of your arteries, which causes your arteries to narrow and can lead to blood clots, a heart attack or a stroke. (clevelandclinic.org)
  • Several studies on atherosclerosis have noted a decrease in native elastin in arteries. (clevelandclinic.org)
  • I'll turn now to atherosclerosis - though I don't currently know whether statins can perform roles other than reducing the build-up of plaque in the arteries. (ussromantics.com)
  • Atherosclerosis is sometimes called 'hardening of the arteries', as sklerosis is from Greek, meaning 'hardening', but it's really a narrowing rather than a hardening, or perhaps it's better described as both, as we'll see. (ussromantics.com)
  • Atherosclerosis of the carotid artery, which feeds the brain, may have different symptoms, including headaches, dyspnea and facial numbness. (ussromantics.com)
  • If you're thinking "atherosclerosis" or "hardening of the arteries," you're in the ballpark. (cardiex.com)
  • The innermost layer, the tunica intima (also called tunica interna), is simple squamous epithelium surrounded by a connective tissue basement membrane with elastic fibers. (onteenstoday.com)
  • These veins usually have a corresponding artery nearby and are in muscle tissue. (veininstitutenj.com)
  • Apparently, these T-cells attack a key protein called elastin thereby leading to death of lung tissue and emphysema. (healthjockey.com)
  • Dense connective tissue proper is composed of a higher density of fibers, which may be regular (with parallel fibers such as that of tendons and ligaments) or irregular (with multidirectional fibers such as that of the pericardium), or elastic (with significant embedded elastin such as that of arteries). (github.io)
  • The paired corpora cavernosa contain erectile tissue and are each surrounded by the tunica albuginea, a dense fibrous sheath of connective tissue with relatively few elastic fibers. (medscape.com)
  • The erectile tissue within the corpora contains arteries, nerves, muscle fibers, and venous sinuses lined with flat endothelial cells, and it fills the space of the corpora cavernosa. (medscape.com)
  • Loss of elastic fibers due to age-related degradation, disease, or injury can lead to loss of tissue integrity and functionality. (elastrin.com)
  • The therapy uses nanoparticles that are conjugated with antibodies that specifically bind to damaged elastin in the tissue. (elastrin.com)
  • EDTA helps to decalcify the tissue while PGG promotes the formation of new, healthy elastin. (elastrin.com)
  • Using protein analyses and tissue studies, the team showed that minoxidil increased elastin deposits in blood vessels. (nih.gov)
  • OPCs are potent antioxidants which protect and repair tissue, and relax arteries. (nasobih.com)
  • These reactive aldehydes and allysines can react with other lysine and allysine residues to form desmosine, isodesmosine, and a number of other polyfunctional crosslinks that join surrounding molecules of tropoelastin into an extensively crosslinked elastin matrix. (wikipedia.org)
  • The induced birefringence demonstrates the highly ordered molecular structure of the elastin molecules in the elastic fiber. (wikipedia.org)
  • Many molecules of a large, flexible molecule called tropoelastin join together to form elastin. (clevelandclinic.org)
  • Microfibrils are believed to play an important role in the early stages of elastic fiber development, acting as a scaffold onto which elastin molecules are deposited. (nih.gov)
  • Another fibrous protein, but this time elastic and stretchy. (stylfile.com)
  • To investigate a function of fibulin-5 in the elastic fiber formation, we studied the molecular interactions among elastin, fibrillin-1, and fibulin-5 in the extracellular space and the maturation of tropoelastin using retinal pigment epithelial cells (ARPE-19). (nih.gov)
  • Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537). (nih.gov)
  • Prior studies with animals suggested that another function of the drug is to turn on the genes for elastin (a protein found in elastic fibers) and other elastic fiber genes, such as Fbn-1 and Lox , causing elastin deposits within the blood vessel wall. (nih.gov)
  • As the elastic fiber grows and matures, the microfibrils move to the outside, forming a wrapping around the elastin core. (nih.gov)
  • The results "indicate that, unlike what was thought before, the progression of Marfan syndrome is not due to failure of formation of an elastic fiber network, but is because the network that forms is defective," says Ramirez. (nih.gov)
  • The permanganate-bisulfite-toluidine blue reaction is a highly selective and sensitive method for demonstrating elastic fibers under polarizing optics. (wikipedia.org)
  • Our objective was to determine the association between environmental lead exposure based on blood lead (B-Pb) concentrations and the prevalence of atherosclerotic plaque in the carotid artery. (nih.gov)
  • The presence of atherosclerotic plaque in the carotid artery was determined by B-mode ultrasonography. (nih.gov)
  • We used logistic regression to estimate odds ratios (ORs) for prevalence of plaque in the carotid artery according to B-Pb quartiles. (nih.gov)
  • Our study shows an association between B-Pb concentrations and occurrence of atherosclerotic plaque in the carotid artery, adding evidence for an underlying pro-atherogenic role of lead in cardiovascular disease. (nih.gov)
  • It is important to be aware, no matter how old you are, of the causes of artery plaque and treatment strategies to prevent serious consequences. (veininstitutenj.com)
  • Since plaque build-up and blood clots are major contributing factors of blocked arteries, poor circulation and cardiovascular diseases, maintaining he. (lifestreamgroup.com)
  • The condition results from the buildup of plaque in the arteries and, in rare cases, the development of blood clots. (disruptedphysician.com)
  • These are the elastic arteries because they are thinner than their diameter. (rightquotes4all.com)
  • The corpus spongiosum possesses a much thinner and more elastic tunica albuginea to allow for distention of the corpus spongiosum for passage of the ejaculate through the urethra. (medscape.com)
  • The aim of our study was to assess the timing of smooth muscle and endothelial proliferation in the carotid arteries in Eln+/- and WT mice. (nih.gov)
  • The tunica media, or middle coat, is thicker in arteries, particularly in the large arteries, and consists of smooth muscle cells intermingled with elastic fibres. (onteenstoday.com)
  • Nevertheless, structural changes in the pulmonary arteries of COPD patients differ from those observed in subjects exposed to a hypoxic environment. (ersjournals.com)
  • In this process tropoelastin, the soluble monomeric precursor to elastic fibers is produced by elastogenic cells and chaperoned to the cell surface. (wikipedia.org)
  • Following deposition onto microfibrils tropoelastin is insolubilized via extensive crosslinking by members of the lysyl oxidase and lysyl oxidase like family of copper-dependent amine oxidases into amorphous elastin, a highly resilient, insoluble polymer that is metabolically stable over a human lifespan. (wikipedia.org)
  • These elastic fibers were evaluated by immunofluorescence staining, the quantitative analysis of cross-linked amino acids, and semi-quantitative analysis of matrix-associated tropoelastin. (nih.gov)
  • Variants in any of these genes disrupt the formation, assembly, or function of elastic fibers. (medlineplus.gov)
  • Some features of WBS have no obvious relationship to elastin but are caused by loss of other genes in the WBSCR. (unboundmedicine.com)
  • We believe that particular cells circulating in the body could react to elastin molecule at these remote sites," continues Kheradmand. (healthjockey.com)
  • Aneurysms are defined as a focal dilatation in an artery, with at least a 50% increase over the vessel's normal diameter. (medscape.com)
  • The tunica intima is surrounded by a thin membrane comprised of elastic fibers running parallel to the vessel. (onteenstoday.com)
  • Marfan's syndrome, a genetic disorder affecting fibrillin synthesis with fibrillin and elastin being basic components of elastic fibre. (escardio.org)
  • On the dorsal aspect of the corpora cavernosa, the deep dorsal vein and paired dorsal arteries and branches of the dorsal nerves are contained within the deep penile (Buck) fascia. (medscape.com)
  • Ferroelectric switching gives elastin the flexibility needed to perform repeated pulses as with an artery. (washington.edu)
  • Elastin microfibril interface located protein 2 (EMILIN2) is an extracellular glycoprotein associated with cardiovascular development. (biomedcentral.com)
  • The narrowing of the arteries means that less blood and oxygen is reaching the cardiovascular system (ischemia), and this may result in vomiting, angina (chest pain), and general feelings of faintness and anxiety. (ussromantics.com)
  • Twin and sibling studies [ 4 ] show that inherited risk factors contribute significantly to the development of coronary artery disease and ischemic stroke. (biomedcentral.com)
  • The heart then pumps it out of the right ventricle and into the pulmonary arteries to begin pulmonary circulation. (physio-pedia.com)
  • Alpha-1 antitrypsin deficiency is a genetic disorder where elastin is excessively degraded by elastase, a degrading protein released by neutrophils during the inflammatory response. (wikipedia.org)
  • Those with elastin-associated SVAS have genetic changes affecting only elastin. (nih.gov)