• oxidative stress
  • 17 Although we found no effects of PEG-CAT on myogenic contractions in afferent arterioles from normal mice, we investigated the effects of bath addition of H 2 O 2 on basal contractility and myogenic responses to determine its potential role in states of vascular oxidative stress. (ahajournals.org)
  • myogenic
  • In conclusion, increasing the pressure within afferent arterioles led to Ca 2+ -independent increased vascular superoxide production from nicotinamide adenine dinucleotide phosphate oxidase, which enhanced myogenic contractions largely independent of NO, whereas H 2 O 2 impaired pressure-induced contractions but was not implicated in the normal myogenic response. (ahajournals.org)
  • Myogenic mechanisms in the afferent arteriole are incompletely understood. (ahajournals.org)
  • endothelial
  • Coloured transmission electron micrograph (TEM) of a section through the wall of an arteriole, showing smooth muscle (brown), endothelial cells (green), and an inner and outer lamina (membrane, blue). (sciencephoto.com)
  • Mitochondrial uncoupling agents could potentially reverse endothelial dysfunction due to HG in intact human arterioles. (ahajournals.org)
  • diameter
  • Arterioles are the smallests vessels of the arterial system, with a diameter of about 1/3 millimeter or smaller. (washington.edu)
  • Saunders and Knisely (63) found unagglutinated blood flowing at physiologic rates through terminal arterioles as narrow as, depending upon species, from 5 to 7.7 micra in diameter. (ebscohost.com)
  • Cells
  • The lumen (centre) of the arteriole is filled with red blood cells. (sciencephoto.com)
  • Constricting the smooth muscle cells in the afferent arteriole, results in a reduced concentration of chloride at the MD. TGF can stabilizes the fluid and solute delivery into the distal portion of the loop of Henle and maintain the rate of filtration near its ideal value using these mechanisms. (wikipedia.org)
  • smaller
  • These arterioles get progressively smaller the more distanced they are from the heart , as most of the blood supply is required by the major organs positioned close to the heart and is provided by the [[arteries. (biology-online.org)
  • conditions
  • We have recently documented the constitutive expression of arginase-I in porcine coronary arterioles and demonstrated its functional role in modulating coronary microvascular tone under physiological 12 and pathophysiological conditions. (ahajournals.org)
  • Simply
  • Simply put, the arterioles in people with FM are remaining too dilated, which the researchers say is causing the nerves to become overly sensitive. (prohealth.com)
  • flow
  • On the ascending portion, NaCl and urea are secreted into the interstitium, while water is reabsorbed The slow blood flow in the straight arterioles makes them a likely location of thrombosis in hypercoagulable states, or tissue loss due to erythrocyte sickling in sickle cell disease. (wikipedia.org)