• Whether decreased aqueous production in the setting of choroidal effusion can occur without a component of inflammation is unclear. (medscape.com)
  • All 3 techniques share the common goal of decreased aqueous production, and all share the possible side effects of inflammation (including possible sympathetic ophthalmia), ineffective treatment, and over-treatment with resultant hypotony or even phthisis. (aao.org)
  • it produces aqueous humor, facilitates trabecular outflow, intervenes in alteration of the shape of the crystalline lens during accommodation, and secretes hyaluronic acid into the vitreous. (medscape.com)
  • The clinical diagnosis is often based on spillover inflammation (i.e., cells and protein flare) observed with a slit lamp in the aqueous or vitreous humors. (aafp.org)
  • The fluids in the eye are divided by the lens into the vitreous humor (behind the lens) and the aqueous humor (in front of the lens). (mountsinai.org)
  • Light that has been focused through the cornea and aqueous humor hits the lens, which then focuses it further, sending the light rays through the vitreous humor and onto the retina. (kidshealth.org)
  • Congenital glaucoma occurs early in life and is the result of marked developmental anterior segment abnormalities affecting the aqueous humor outflow pathway and obstructing flow. (vin.com)
  • The terms open angle and angle closure describe the basic structural issue within the eye that is disrupting aqueous flow. (allaboutvision.com)
  • In angle-closure forms, the aqueous can't leave the eye because the iris is blocking the drainage angle. (allaboutvision.com)
  • Although there is not uniform agreement, most surgeons reserve cycloablation procedures for those cases refractory to, or not amenable to, procedures that improve aqueous outflow such as angle surgery, glaucoma drainage implant surgery, and trabeculectomy ( Table 1 ). (aao.org)
  • The iridocorneal angle is bordered by the peripheral cornea, anterior sclera, iris base, and anterior ciliary body. (vin.com)
  • This flow blockage might occur at the pupil, iridocorneal angle, or ciliary cleft. (vin.com)
  • In this most common form of glaucoma, the angle where the cornea and the iris meet is open, but the aqueous humor fluid passes too slowly through the meshwork drain. (healthywomen.org)
  • These sides affects may include reduction of body potassium when treating sudden attacks of extremely high eye pressure, as what happens in acute angle closure glaucoma. (oomc.com)
  • In open angle glaucoma, aqueous fluid drains too slowly and pressure inside the eye builds up. (preventblindness.org)
  • Too much aqueous production or obstruction of its outflow causes a rise in IOP that can lead to glaucoma. (allaboutvision.com)
  • With secondary glaucoma, there are known, specific factors directly affecting aqueous flow and IOP. (allaboutvision.com)
  • In light of newer cyclodestructive procedures that can be gentler and more precise (see below), cyclocryotherapy should be reserved for those refractory pediatric glaucoma cases in which anatomy limits the likelihood of successful ciliary body treatment with either trans-scleral or endoscopic cyclophotocoagulation (below) or access to these technologies is truly unavailable and incisional surgery is impossible or has been exhausted. (aao.org)
  • Hypersecretory glaucoma (i.e., increased aqueous production with a normal drainage apparatus) is not known to occur in animals. (vin.com)
  • Primary glaucoma results from a variety of poorly understood abnormalities that block aqueous outflow from the eye. (vin.com)
  • Secondary glaucoma results from various insults to the ocular aqueous humor outflow mechanism. (vin.com)
  • Glaucoma occurs when grains of pigment from the back of the iris flake off into the aqueous humor, eventually clogging the drainage meshwork and raising eye pressure. (healthywomen.org)
  • The use of aqueous shunts or valves to manage glaucoma has been rising, and the outcomes of a current study have demonstrated improved security and efficacy of those devices. (atpobtvs.com)
  • The company's CyPass Micro-Stent is a micro-invasive glaucoma stent designed to reduce IOP by enhancing aqueous outflow to the suprachoroidal space, one of the eye's natural, alternative drainage pathways. (cbinsights.com)
  • Uveoscleral outflow is across the ciliary body and iris to the suprachoroidal space and out the posterior choroidal circulation. (vin.com)
  • Dilator pupillae muscle lies in the posterior part of stroma of the ciliary zone of iris. (opthametry.com)
  • Treatment includes laser surgery and/or topical medications (eg, prostaglandin analogs, beta-blockers) and often requires incisional surgery to increase aqueous drainage. (msdmanuals.com)
  • Active aqueous humor production occurs in the non-pigmented ciliary epithlial cells of the ciliary processes. (medscape.com)
  • Cyclodestruction procedures aim to decrease intraocular pressure (IOP) by decreasing production of aqueous humor by the ciliary body (specifically the ciliary processes). (aao.org)
  • This technique, the oldest cyclodestructive method, involves freezing the ciliary processes from an external approach ( Figure 1 ). (aao.org)
  • Aqueous humor is produced by the ciliary body processes through active secretion, passive diffusion, dialysis, and ultrafiltration. (vin.com)
  • secreted by the ciliary processes. (theeyecenter.com)
  • Parasympathomimetic drugs cause contraction of the muscles associated with the ciliary body and of the iris sphincter. (wedgewoodpharmacy.com)
  • It is held in place by the ciliary muscles, which allow the lens to change shape depending on the amount of light that hits it so it can be properly focused. (md-health.com)
  • The ciliary muscles within the ciliary body allow for the viewing of objects at varying distances and regulate the flow of fluid (aqueous humor) throughout the eye. (viteyes.com)
  • Ciliary muscles help in accommodation. (opthametry.com)
  • The remaining 10-40% exits via the uveoscleral outflow, where it crosses the ciliary body, sclera, or scleral openings to reach the suprachoroidal space. (medscape.com)
  • It is connected to the lens with a network of many tiny ligaments (called ciliary zonules or zonules of Zinn) that suspend the lens in place behind the pupil. (allaboutvision.com)
  • The ciliary body also secretes the clear aqueous fluid that fills the space in the anterior segment of the eye between the cornea and the iris and lens, and it contains the muscle that controls accommodation of the eye. (allaboutvision.com)
  • The aqueous secretory inhibitors and pilocarpine may not be efficient as a result of ischemia of the ciliary body and pupillary sphincter, respectively. (atpobtvs.com)
  • Flowing through this chamber is a liquid, called the aqueous humor, which supplies oxygen and nutrients to the cornea and lens and helps maintain the shape of the eyeball. (healthywomen.org)
  • Oral administration of GTE reduces significantly infiltration of inflammatory cells and exudation of proteins in the aqueous humor, which are associated with reduced expression and secretion of proinflammatory factors in the ciliary body and iris 13 . (nature.com)
  • This necessitates the investigation of past experimental approaches in their attempt to correlate oxidative stress and ocular diseases in humans in both the epithelial cells plus the capsule (LECs/capsule) and in the aqueous humor (AH). (molvis.org)
  • The -blocking brokers produce ocular hypotensive results by lowering the manufacturing of aqueous humor by the ciliary body with out producing substantial effects on aqueous humor outflow facility. (atpobtvs.com)
  • Ciliary body is a ring-shaped tissue which holds and controls the movement of the eye lens, and thus, it helps to control the shape of the lens. (md-health.com)
  • This condition allows both protein and WBCs to extravasate into the aqueous, resulting in the typical iritis signs of cell and flare. (medscape.com)
  • The outer layer is composed of lipid from the meibomian glands, the middle aqueous layer is from the lacrimal gland and the third eyelid gland, and the inner layer of mucus that attaches the tear film to the cornea is from the conjunctival goblet cells. (merckvetmanual.com)
  • In small animals, conventional outflow is the primary mechanism by which aqueous humor exits the globe. (vin.com)