Application administration topical. Medical search. Frequent questions

Systemic absorption of topical corticosteroids may occur depending on the vehicle and concentration of the preparation, the size of the application area, the integrity of the skin, and the duration of administration. (drugs.com)
The same adverse reactions found with systemic administration of beta-adrenergic blocking agents may occur with topical administration. (theodora.com)
In addition, patients were inadequately controlled with topical therapy or were candidates for systemic/phototherapy. (jnj.com)

The development of this technique of drug delivery eliminates many of the challenges related to oral administration of the desired drugs. (scienceblog.com)
Amitrole was tested in mice by oral administration, skin application and transplacental exposure, in rats by oral and subcutaneous administration, and in hamsters by oral administration. (inchem.org)
In rats, amitrole induced thyroid and pituitary tumours after oral administration. (inchem.org)
Lidocaine Viscous (Lidocaine Hydrochloride Oral Topical Solution USP) contains a local anesthetic agent and is administered topically. (druglib.com)
Some companies promoted the ibuprofen topicals as superior to oral ibuprofen because they didn't carry the same risk of side effects, such as stomach ulcers. (abmp.com)
Based on route of administration, the market is segmented into oral and topical. (bharatbook.com)
Lidocaine Hydrochloride Topical Solution USP is indicated for the production of topical anesthesia of accessible mucous membranes of the oral and nasal cavities and proximal portions of the digestive tract. (drugs.com)
Topical NSAIDs represent an attractive alternative to oral forms of the drug, providing pain relief while avoiding the various risks and adverse effects of oral NSAIDS that can be a particular concern in elderly patients, including gastrointestinal, cardiovascular, and renal adverse events. (medscape.com)
Although there are no head-to-head studies comparing oral with topical NSAIDs, the treatment effects are comparable, he added. (medscape.com)

Lidocaine is absorbed following topical administration to mucous membranes, its rate and extent of absorption being dependent upon concentration and total dose administered, the specific site of application, and duration of exposure. (druglib.com)

Common adverse reactions include irritation on topical application. (wikidoc.org)
If irritation on topical application should occur, discontinue medication. (wikidoc.org)

Topical calcineurin inhibitors are non-steroidal immunomodulators. (rchsd.org)

Occupational exposures occur during production, formulation and application of this herbicide, and nonoccupational exposures may occur from residues in food. (inchem.org)
AMZEEQ™ is the first topical formulation of minocycline. (globenewswire.com)
Acute dermal toxicity studies on SNP gel formulation (S-gel) in Sprague-Dawley rats showed complete safety for topical application. (nih.gov)
These results clearly indicate that silver nanoparticles could provide a safer alternative to conventional antimicrobial agents in the form of a topical antimicrobial formulation. (nih.gov)
September 28, 2011 (San Diego, California) - A topical formulation of the nonsteroidal anti-inflammatory drug (NSAID) diclofenac sodium 1% gel ( Voltaren Gel , Endo Pharmaceuticals) shows safety and efficacy in relieving knee osteoarthritis pain in both younger and elderly patients, according to research presented here at the American Academy of Pain Management (AAPM) 22nd Annual Clinical Meeting. (medscape.com)

Therapy with topical corticosteroids rarely produces these effects but should be administered cautiously nonetheless in patients with diabetes mellitus, glucose intolerance, or a predisposition to hyperglycemia. (drugs.com)
Pace WE "Topical corticosteroids. (drugs.com)
Topical corticosteroids, especially the potent agents (e.g., augmented betamethasone, clobetasol, diflorasone, and halobetasol), are generally not recommended for use in the treatment of diaper rash. (drugs.com)
Topical corticosteroids may be systemically absorbed, depending on the vehicle and concentration of the preparation, the size of the application area, the duration of administration, and whether or not occlusive dressings are used. (drugs.com)
If topical corticosteroids are necessary to treat diaper rash, medium- to low-potency agents should preferably be used, and parents should be advised not to put tight-fitting diapers or plastic pants over the rash, since occlusion of treated area may increase percutaneous drug absorption. (drugs.com)
Ruiz-Maldonado R, Zapata G, Lourdes T, Robles C "Cushing's syndrome after topical application of corticosteroids. (drugs.com)
ABSTRACT To analyse the prescribing pattern of topical corticosteroids, 802 outpatient dermatology prescriptions were randomly collected during June 2003-September 2003 from all the 12 nongovern- mental dermatological clinics in north Palestine. (who.int)
Of the 2458 medications prescribed, 616 were topical corticosteroids. (who.int)
One effects of topical corticosteroids because step to achieve this is to monitor, evaluate percutaneous absorption is greater [ 17 ]. (who.int)
The authors concluded tics, antifungals, antivirals, antihistamines, that health care professionals need to give local anaesthetics, emollients, keratolytics, patients more information about their topi- antiparasitics and topical corticosteroids. (who.int)
Topical corticosteroids, which were intro- withheld from those who need it. (who.int)
The purpose of this study is to evaluate the practice of dermatology and they still and analyse the pattern of prescribing topical constitute one of the largest groups of drugs corticosteroids among outpatients attending used in this discipline. (who.int)

In general, the rate of absorption of local anesthetic agents following topical application occurs most rapidly after intratracheal administration. (druglib.com)
For more information, see Local Anesthetic Agents, Infiltrative Administration . (medscape.com)

Pimecrolimus (Elidel®) cream 1 percent, marketed by Novartis Pharmaceutical Corporation, has been approved by the Food and Drug Administration for use in patients 2 years of age or older with mild to moderate atopic dermatitis. (rchsd.org)
It has been studied extensively in children with atopic dermatitis in large multicenter controlled trials with application twice daily for up to 12 months. (rchsd.org)
A study carried out in Nottingham showed outcome of the dermatological prescription that nearly three quarters of patients with analysis will be a message to the prescribing atopic eczema worried about using topical physician to achieve rational, cost-effective steroids and almost a quarter were non- medical care. (who.int)

Retin-A may interact with other topical medications, especially those containing sulfur, resorcinol, or salicylic acid . (rxlist.com)
Aczone Gel 5% may interact with other topical medications, harsh or abrasive soaps, or cosmetics on the affected area. (rxlist.com)

Tacrolimus ointment, marketed by Fujisawa Healthcare Inc. as Protopic® 0.03 percent for children 2 to 15 years of age, and 0.03 percent and 0.1 percent for adults, has been approved by the Food and Drug Administration for short-term and intermittent long-term use in moderate-to-severe eczema. (rchsd.org)

Despite being the most common route of ophthalmic drug administration, eye drops are associated with compliance issues, drug wastage by lacrimation, and low bioavailability due to the ocular barriers. (mdpi.com)

Proctocream HC (hydrocortisone-pramoxine topical). (drugs.com)
Pandel (hydrocortisone topical). (drugs.com)
The other ingredient in Xyloproct is hydrocortisone which is a topical steroid. (euroclinix.net)

Results of the study, Topical Delivery of Tenofovir Disoproxil Fumarate and Emtricitabine from Pod-Intravaginal Rings Protect Macaques from Multiple SHIV Exposures, confirm that the combination of tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) delivered at independently controlled rates via the pod-IVR were successful at preventing SHIV162p3 infection in a rigorous, repeat low-dose vaginal exposure model using normally cycling female pigtailed macaques. (scienceblog.com)
Research suggests topical applications may help protect the skin from sun exposure and changes in pigmentation. (medicalnewstoday.com)

Risks are also attributable to the route of administration, as most of these medications are taken orally, which increases the risk of adverse effects. (naturalmedicinejournal.com)
12,13 This route of administration avoids potential gastrointestinal adverse effects, as well as first-pass metabolism. (naturalmedicinejournal.com)
Schematic illustration of replaced administration route from invasive ocular injection to topical eye drop for treatment of posterior diseases. (itri.org.tw)
The report segments the market for antibiotics based on product type, route of administration, application and geographical region. (bharatbook.com)
In most prescriptions, information about strength, duration of treatment and quantity to be used was inadequate, while information regarding frequency, route and area of application was adequate. (who.int)

For more information, see Anesthesia, Topical . (medscape.com)

Diprosalic Scalp Application is a topical corticosteroid treatment that is designed for use on your scalp. (healthexpress.co.uk)
An effective treatment for various skin conditions, Diprosalic Scalp Application is commonly prescribed for psoriasis and eczema (dermatitis) . (healthexpress.co.uk)
Azelaic Acid Gel, 15% is indicated for topical treatment of the inflammatory papules and pustules of mild to moderate rosacea. (nih.gov)
XEGLYZE is a pediculicide indicated for the topical treatment of head lice infestation in patients 6 months of age and older. (nih.gov)
Treatment with XEGLYZE involves a single application. (nih.gov)
Revolution Plus is a monthly treatment that is a 6-in-1 topical solution that also prevents fatal heartworm disease. (petcarerx.com)
99m Tc-labeled CSCs treatment via topical administration. (itri.org.tw)
Radiographic images of rat eye post 99m Tc-labeled CSCs treatment via topical administration. (itri.org.tw)
A non-controlled clinical study, in patients with antibiotic-resistant stomatitis caused by Candida albicans , topical treatment with saponins from primula root, led to the disappearance of local symptoms within 2-3 days. (escop.com)
Retin-A (tretinoin) Cream and Gel is a form of Vitamin A used for the topical treatment of acne vulgaris . (rxlist.com)
RETIN-A Gel, Cream and Liquid, containing tretinoin are used for the topical treatment of acne vulgaris . (rxlist.com)
RETIN-A is indicated for topical application in the treatment of acne vulgaris. (rxlist.com)
In cases where it has been necessary to temporarily discontinue therapy or to reduce the frequency of application, therapy may be resumed or frequency of application increased when the patients become able to tolerate the treatment. (rxlist.com)
Endo Pharmaceuticals announced that FORTESTA Gel - recently approved by the U.S. Food and Drug Administration for the treatment of low testosterone, or 'Low T' in adult males - is now available by prescription in pharmacies across the country. (news-medical.net)
Aczone ( dapsone ) Gel, 5% is a sulfone drug indicated for the topical treatment of acne vulgaris . (rxlist.com)
ACZONE ® (dapsone) Gel, 7.5%, is indicated for the topical treatment of acne vulgaris in patients 12 years of age and older. (rxlist.com)
Essential oils are available in the United States for inhalation and topical treatment. (cancer.gov)
Aromatherapy products are not subject to approval by the U.S. Food and Drug Administration unless there is a claim for treatment of specific diseases. (cancer.gov)
Foamix recently received FDA approval for AMZEEQ™ (minocycline) topical foam, 4%, for the treatment of inflammatory lesions of non-nodular moderate-to-severe acne vulgaris in adults and pediatric patients 9 years of age and older. (globenewswire.com)
Foamix recently submitted a New Drug Application to the U.S. Food and Drug Administration (FDA) for FMX103 (minocycline) topical foam, for the treatment of moderate-to-severe papulopustular rosacea. (globenewswire.com)
Foamix is also conducting a Phase II trial for FCD105, a topical combination foam of minocycline and adapalene, currently being evaluated for the treatment of moderate-to-severe acne vulgaris. (globenewswire.com)
The only treatment-related adverse event that was more common in the treatment group compared with the vehicle group was application site dermatitis, which was seen in younger (4.0% vs 0.7%), as well as older (5.8% vs 0.4%), patients. (medscape.com)

Lidocaine Hydrochloride Topical Solution USP 4% contains a local anesthetic agent and is administered topically. (drugs.com)
Lidocaine Hydrochloride Topical Solution USP is contraindicated in patients with a known hypersensitivity either to local anesthetics of the amide type or to the components of the topical solution. (drugs.com)

It can be used to treat both internal and external haemorrhoids thank to the included nozzle for easy application and can reduce the duration of an attack. (euroclinix.net)

Wash hands immediately following application. (nih.gov)

Topical pain relievers-whether in the form of creams, gels, lotions, or oils-can be useful tools in a massage therapist's kit. (abmp.com)

WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. (wikidoc.org)
As a targeted topical medication it is able to get straight to work providing pain relief in as little as a few seconds after application. (euroclinix.net)
Although as a topical medication serious side effects are unlikely you may experience a tingling/burning sensation when you first apply it. (euroclinix.net)

Lidex (fluocinonide topical). (drugs.com)

Carruthers JA, Staughton RC, August PJ "Penetration of topical steroid preparations. (drugs.com)

In patients with hair loss, the topical prostaglandin analogs have better therapeutic efficacy and safety than placebo. (frontiersin.org)
I would expect the therapeutic effect to be related to its half-life, and benefits rely on continued applications of the gel," he said. (medscape.com)

Elocon (mometasone topical). (drugs.com)

For 2 weeks after XEGLYZE application, avoid taking drugs that are substrates of CYP3A4, CYP2B6 or CYP1A2. (nih.gov)
The routes of administering medicines are many and are similar to application of medicines in other animals, though the quantities of drugs that the practitioner would deal with would be drastically different from the regular cat/dog. (vin.com)

Contact irritant dermatitis and facial hirsutism ( 15 , 16 ) are also seen after topical application. (frontiersin.org)

Once the acne lesions have responded satisfactorily, it may be possible to maintain the improvement with less frequent applications, or other dosage forms. (rxlist.com)

Aromatherapy has a relatively low toxicity profile when administered by inhalation or diluted topical application. (cancer.gov)

In August 2009, the Food and Drug Administration (FDA) issued warnings to eight companies for illegally marketing such compounds. (abmp.com)

ACZONE (dapsone) Gel, 7.5%, contains dapsone, a sulfone, in an aqueous gel base for topical dermatologic use. (rxlist.com)

Given the lower risk of adverse effects and the high reported tolerability, topical cannabidiol treatments for chronic pain may represent an underutilized therapy. (naturalmedicinejournal.com)

Animal models show topical penetration of cannabinoids into underlying tissues, as well as dose-dependent anti-inflammatory and pain-relieving effects. (naturalmedicinejournal.com)

no skin tumour was observed after topical application. (inchem.org)
This revised draft guidance provides recommendations for the design and conduct of studies to evaluate the in vivo skin irritation and sensitization (I/S) potential of a proposed transdermal or topical delivery system (collectively referred to as TDS). (fda.gov)
The goal of this study was to evaluate interaction between oxidative stress in the skin and topical application of MWF. (cdc.gov)
Intradermal administration of GOD-PEG to B6C3F1 mice (female and male, 8-12 weeks old) resulted in inflammation and muscle fiber necrosis in the skin. (cdc.gov)
Using a topical antiseptic agent during routine bathing and/or skin preparation for sterile procedures can help reduce bacterial skin colonization in newborns. (msdmanuals.com)

The duration of the therapy depends on factors such as the topical corticosteroid potency, disease severity and anatomic location, and age. (pdr.net)

Cats may experience hypersalivation, tremors, vomiting and decreased appetite if Advantage Multi for Cats is inadvertently administered orally or through grooming/licking of the application site. (chewy.com)

Given the high tolerability, positive safety profile, and low risk of drug interactions of topical products derived from Cannabis spp, the administration of them for chronic pain may represent an underutilized form of therapy. (naturalmedicinejournal.com)
There are 5 disease interactions with fluocinolone topical. (drugs.com)

The application is supported by data from the Phase 3 CADMUS registration study, which evaluated the efficacy and safety, as well as improvements in quality of life, among adolescents (pediatric patients ages 12 to 17) receiving STELARA compared with patients receiving placebo. (jnj.com)
Patients (N=110) had been diagnosed more than six months prior to first study agent administration with a Psoriasis Area Severity Index (PASI) score greater than or equal to 12, a Physician's Global Assessment (PGA) score greater than or equal to 3 and body surface area (BSA) involvement of at least 10 percent. (jnj.com)
The patients were treated with 4 g topical diclofenac (Voltaren Gel) or a vehicle 4 times daily. (medscape.com)
The improvement in older patients treated with topical diclofenac was similarly improved compared with the vehicle group in terms of WOMAC pain score ( P = .85), physical function ( P = .70), global rating of disease ( P = .86), and pain on movement ( P = .81). (medscape.com)

In humans, relief of painful joints and sore muscles is one of the most commonly reported uses of topical cannabis products. (naturalmedicinejournal.com)

Topical treatments are generally used in diluted forms. (cancer.gov)

The purpose of this meta-analysis is to determine the efficacy and safety of topical prostaglandin analogs for treating hair loss. (frontiersin.org)
This industry-sponsored study adds to a growing evidence base in support of the safety and efficacy of topical diclofenac for osteoarthritis of the knee," said Dr. Reisfield, an assistant professor and director of the Division of Pain and Palliative Medicine at the University of Florida College of Medicine's Department of Community Health & Family Medicine in Jacksonville. (medscape.com)

Topical anesthetics are used to reduce the pain caused by needle insertion. (medscape.com)

The widespread availability of CBD products sold and marketed as dietary supplements in the United States is confounding given that the US Food and Drug Administration (FDA) has explicitly stated that as an active pharmaceutical ingredient in an FDA-approved drug (ie, Epidiolex ® , Greenwich Biosciences Inc.), CBD is precluded from being added to food and beverages or included in dietary supplements. (naturalmedicinejournal.com)
3 Nonetheless, consumer demand for CBD is high and growing, including demand for topical products, which are not foods, beverages, or dietary supplements and, thus, may not violate FDA regulations, assuming no drug claims are made in marketing materials. (naturalmedicinejournal.com)
Generally, topical application of medicines is problematic since the drug washes off as soon as fish are returned to the water. (vin.com)
BioSante Pharmaceuticals, Inc. today announced that a New Drug Application (NDA) has been accepted for filing by the U.S. Food and Drug Administration (FDA) following submission in January 2011 by a subsidiary of Teva Pharmaceutical Industries Ltd.. The FDA has assigned a PDUFA date of November 14, 2011. (news-medical.net)
The Food and Drug Administration (FDA or Agency) is announcing the availability of a revised draft guidance for industry entitled "Assessing the Irritation and Sensitization Potential of Transdermal and Topical Delivery Systems for ANDAs. (fda.gov)
The recommendations in this revised draft guidance relate to studies submitted in support of an abbreviated new drug application (ANDA). (fda.gov)
Voltaren was approved by the US Food and Drug Administration for osteoarthritic pain in 2007. (medscape.com)
We measured vaccine uptake and inability to swallow pills and monitored cadets for 90 days after vaccination for US Food and Drug Administration- defined serious adverse events ( 9 ). (cdc.gov)
US Food and Drug Administration-approved use of a ness of breath (11.6%) (Table). (cdc.gov)

Diprosalic Scalp Application contains two active ingredients. (healthexpress.co.uk)

Advantage Multi for Cats is a broad-spectrum topical solution prescribed by veterinarians to provide pet parents with a convenient monthly application to help alleviate symptoms caused by pesky parasites. (chewy.com)

Topical agents for treating chronic pain represent a small percentage of the total global market for prescription and over-the-counter (OTC) analgesics ($8.9 billion in 2019 out of an estimated $71.4 billion). (naturalmedicinejournal.com)

Eli Lilly and Company announced today that Axiron® (testosterone) topical solution is available in pharmacies throughout the United States. (news-medical.net)
ADVANTAGE MULTI Topical Solution for Cats, 9.1-18 lbs, (Purple Box), 12 Doses (12-mos. (chewy.com)

These studies, with hamamelis water administered as a topical preparation, demonstrated its use and improved the symptoms in UV-induced erythema. (escop.com)

very moist lesions, however, are best treated with nystatin topical powder. (wikidoc.org)

This usually involves the application of a paste/gel onto an external lesion. (vin.com)
A Feature Paper should be a substantial original Article that involves several techniques or approaches, provides an outlook for future research directions and describes possible research applications. (mdpi.com)

Anatomy17

Organisms20

Diseases9

Chemicals and Drugs70

Analytical, Diagnostic and Therapeutic Techniques and Equipment84

Psychiatry and Psychology3

Phenomena and Processes46

Disciplines and Occupations7

Anthropology, Education, Sociology and Social Phenomena3

Technology, Industry, Agriculture9

Information Science11

Health Care18

Geographicals1

Systemic3

Oral9

Mucous membranes1

Irritation on topical application2

Calcineurin inhibitors1

Formulation5

Corticosteroids12

Local anesthetic agents2

Atopic3

Interact with other topical medications2

Ointment1

Ophthalmic1

HYDROCORTISONE3

Exposure2

Route5

Anesthesia1

Treatment22

Lidocaine2

Haemorrhoids1

Wash1

Creams1

Medication3

Lidex1

Steroid1

Therapeutic2

Elocon1

Drugs2

Dermatitis1

Dosage Forms1

Toxicity1

Warnings1

Aqueous1

Adverse Effects1

Penetration1

Skin5

Duration1

Orally1

Interactions2

Patients4

Commonly1

Treatments1

Efficacy2

Anesthetics1

Drug9

Contains two active1

Parasites1

Agents1

Solution2

Symptoms1

Lesions1

Involves2