LigandsApoptosisApoptosis Regulatory ProteinsCaspasesCaspase 3Fas Ligand ProteinProto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsDNA FragmentationSignal TransductionCell Line, TumorIn Situ Nick-End Labelingbcl-2-Associated X ProteinX-Linked Inhibitor of Apoptosis ProteinCell SurvivalCD40 LigandCells, CulturedCASP8 and FADD-Like Apoptosis Regulating ProteinApoptosis Inducing FactorCaspase 9Caspase InhibitorsCaspase 8Tumor Cells, CulturedCell LineEnzyme ActivationTNF-Related Apoptosis-Inducing LigandMitochondriaTumor Suppressor Protein p53Cytochromes cMembrane GlycoproteinsCell Proliferationbcl-X ProteinFlow CytometryBlotting, WesternProtein BindingTransfectionAnnexin A5Proto-Oncogene ProteinsAmino Acid Chloromethyl KetonesCysteine Proteinase InhibitorsAntineoplastic AgentsCell CycleMolecular Sequence DataJurkat CellsMice, Inbred C57BLDose-Response Relationship, DrugCell DivisionEnzyme InhibitorsPoly(ADP-ribose) PolymerasesRNA, MessengerDown-RegulationTumor Necrosis Factor-alphaPhosphorylationRNA, Small InterferingAmino Acid SequenceReactive Oxygen SpeciesUp-RegulationReceptors, TNF-Related Apoptosis-Inducing LigandBinding SitesHL-60 CellsCarrier ProteinsMembrane ProteinsCell DeathReverse Transcriptase Polymerase Chain ReactionTime FactorsMice, KnockoutCaspase 7Membrane Potential, MitochondrialNF-kappa BCytochrome c GroupGenes, bcl-2Gene Expression RegulationRANK LigandRecombinant ProteinsProto-Oncogene Proteins c-aktNecrosisbcl-2 Homologous Antagonist-Killer ProteinBH3 Interacting Domain Death Agonist ProteinProtein Structure, TertiaryImmunohistochemistryMyeloid Cell Leukemia Sequence 1 ProteinReceptors, Tumor Necrosis FactorMutationModels, MolecularDNA DamageGene Expression Regulation, NeoplasticModels, BiologicalGene ExpressionHeLa CellsProteinsDrug SynergismStaurosporineProtein-Serine-Threonine KinasesKineticsNeoplasm ProteinsCell DifferentiationT-LymphocytesIntracellular Signaling Peptides and Proteinsbcl-Associated Death ProteinDNA-Binding Proteins