• inhibitor of apoptosis prot
  • The inhibitory potency of acetyl-Asp-Glu-Val-Asp-aldehyde ('Ac-DEVD-CHO'), benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone ('Z-VAD-FMK') and the endogenous caspase inhibitor X-chromosome-linked inhibitor of apoptosis protein ('XIAP') against recombinant caspase-9 were predictive of the efficacy of these compounds in a cell-free system. (biochemj.org)
  • What does x-linked inhibitor of apoptosis protein mean? (phrases.net)
  • Molecular antagonists of the inhibitor of apoptosis protein survivin have shown promise as novel anticancer strategies for triggering tumor cell apoptosis, dysregulating mitotic progression, and inhibiting tumor growth in preclinical models. (aacrjournals.org)
  • factor
  • Adenoviral transduction of endothelial cells with pAd-Survivin inhibited growth factor deprivation- or ceramide-induced apoptosis, reduced caspase-3 and -7 generation, and stabilized three-dimensional capillary networks in vitro . (aacrjournals.org)
  • cells
  • CardioTACS™ In Situ Apoptosis Detection Kits Ordering Information ORDER ONLINE 4827-30-K CardioTACS Kit, 30 Samples $285 The CardioTACS Kit was developed to provide the heart researcher with an effective method for identifying apoptotic cells in cardiac samples. (selectscience.net)
  • In situ detection of apoptosis in fixed frozen, paraffin embedded, or plastic embedded cardiac cells and tissues. (selectscience.net)
  • Conversely, expression of pAd-T34A caused apoptosis in umbilical vein and dermal microvascular endothelial cells and resulted in caspase-3 activity. (aacrjournals.org)
  • Thus, we now show that selection for interferon resistance can generate cells with increased expression of cFLIP, which protects the cells from both IFN-α and death receptor mediated apoptosis. (diva-portal.org)
  • In Hq mice, instead of supernumerary cells attributable to failed apoptosis, surprisingly their cerebellum degenerates progressively and Hq neurons are more sensitive to oxidative stress. (jneurosci.org)