RotenoneApoptosisUncoupling AgentsCaspasesApoptosis Regulatory ProteinsCaspase 3Electron Transport Complex IInhibitor of Apoptosis ProteinsProto-Oncogene Proteins c-bcl-2DNA FragmentationAntimycin ACell Line, TumorReactive Oxygen SpeciesCell SurvivalIn Situ Nick-End Labelingbcl-2-Associated X ProteinX-Linked Inhibitor of Apoptosis ProteinCells, CulturedApoptosis Inducing FactorSignal TransductionCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 9Caspase InhibitorsEnzyme ActivationCytochromes cCaspase 8MitochondriaFas Ligand ProteinTumor Suppressor Protein p53OligomycinsTumor Cells, CulturedEnzyme InhibitorsCell LineCell DeathNADH DehydrogenaseMembrane Potential, MitochondrialBlotting, Westernbcl-X ProteinCell ProliferationElectron TransportDose-Response Relationship, DrugAnnexin A5Oxidative StressParkinsonian DisordersHydrogen PeroxideParkinson Disease, SecondaryAmino Acid Chloromethyl KetonesCysteine Proteinase InhibitorsNAD(P)H Dehydrogenase (Quinone)Proto-Oncogene ProteinsFlow CytometryCell CycleCytochrome c GroupAntineoplastic AgentsPoly(ADP-ribose) PolymerasesTransfectionInsecticides1-Methyl-4-phenylpyridiniumParaquatTime FactorsNeuronsTNF-Related Apoptosis-Inducing LigandJurkat CellsStaurosporinePhosphorylationCell DivisionSubmitochondrial ParticlesRNA, Small InterferingAmobarbitalCaspase 7HL-60 CellsMitochondria, HeartDown-RegulationMice, Inbred C57BLRNA, MessengerOxidation-ReductionDrug SynergismNADH, NADPH OxidoreductasesThenoyltrifluoroacetoneRutamycinMalatesTumor Necrosis Factor-alphaRats, Sprague-DawleyGenes, bcl-2Carbonyl Cyanide p-TrifluoromethoxyphenylhydrazoneSuperoxidesUbiquinoneNADCytoprotectionMitochondria, Liverbcl-2 Homologous Antagonist-Killer ProteinCyanidesMembrane GlycoproteinsAntioxidantsNecrosisAdenosine TriphosphateDopamineSuccinic AcidUp-RegulationOxygen Consumption