Apoptosis protein structure tertiary. Medical search. Frequent questions

Exposure of sensitive cell lines with PFI-1 results in G1 cell-cycle arrest, downregulation of MYC expression, as well as induction of apoptosis and induces differentiation of primary leukemic blasts. (ox.ac.uk)
Notch activator cyclopiazonic acid induces apoptosis in HL-60 cells through calcineurin activation. (go.jp)
Purpose: Previous in vitro and in vivo studies have reported that 1'-S-1'-acetoxychavicol acetate (ACA) isolated from rhizomes of the Malaysian ethno-medicinal plant Alpinia conchigera Griff (Zingiberaceae) induces apoptosis-mediated cell death in tumour cells via dysregulation of the NF-κB pathway. (oncotarget.com)

Many factors, such as peroxide, ox-low density lipoprotein (LDL), angiotensin I, and tumor-necrosis-factor-(TNF-) α can induce the production of reactive oxygen species (ROS) by NADPH oxidase in endothelium and vascular smooth muscle [ 2 ], which results in oxidative stress to the endothelial cells (ECs) and, thus, the induction of cell apoptosis. (hindawi.com)
RCD, referring to apoptosis, necrosis and autophagy, can be triggered either via intrinsic or extrinsic cell stimuli. (parasite-journal.org)
RT can directly induce cancer cell death through various mechanisms, such as apoptosis, necrosis, and autophagy. (nature.com)

The calpains ostensibly participate in a variety of cellular processes including remodelling of cytoskeletal/membrane attachments, different signal transduction pathways, and apoptosis. (embl.de)
The mechanism of action of this compound involves the inhibition of key enzymes and proteins involved in cell function and signal transduction pathways. (evitachem.com)
Cell signaling: Hormones and their receptors, cell surface receptor, signaling through G-protein coupled receptors, signal transduction pathways, second messengers, regulation of signaling pathways, bacterial and plant two-component signaling systems, bacterial chemotaxis and quorum sensing. (pathfinderacademy.in)

MAPKs are involved in directing cellular responses to a diverse array os stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines regulating cell functions including proliferation, gene expression, differentiation, mitosis, cell survival or apoptosis. (wikipedia.org)
In cardiac conditional Ezh2-knockout mice, cardiomyocyte proliferation was repressed, and the apoptosis process was induced [ 10 ]. (hindawi.com)
The hallmarks of development during pregnancy are the formation of tertiary branches, which terminate in alveolar buds, and the rapid proliferation of the luminal epithelium accompanied by differentiation and commitment to the secretory alveolar lineage. (biologists.com)
Pathway analysis of these 42 human proteins shows that they are involved in key host cellular processes related to cell cycle regulation, proliferation, protein degradation, apoptosis, and immune responses. (springernature.com)
This compound has been shown to induce apoptosis in cancer cells by inhibiting the activity of key enzymes involved in cell survival and proliferation. (evitachem.com)

The negative supercoiling of DNA can induce sequence-dependent conformational changes that give rise to local DNA structures and alternative DNA conformations such as cruciforms, A-DNA, left-handed DNA (Z-DNA), triplexes, four-stranded DNA (quadruplexes) and others [ 2 , 3 ]( ref )" But we don't really get into most of those other types here. (anti-agingfirewalls.com)
If the damage is extensive, it can induce APOPTOSIS. (lookformedical.com)

The gene of cIAP1 resides on chromosome 11 and its protein has a quaternary structure. (wikipedia.org)

Strikingly, overexpression of imd leads to constitutive transcription of these genes and to apoptosis, and both effects are blocked by coexpression of the caspase inhibitor P35. (cnrs.fr)
Bromo and extra terminal (BET) proteins (BRD2, BRD3, BRD4, and BRDT) are transcriptional regulators required for efficient expression of several growth promoting and antiapoptotic genes as well as for cell-cycle progression. (ox.ac.uk)
Our data show that the stable knockdown of HIPK2 led to wtp53 misfolding, as detected by p53 immunoprecipitation with conformation-specific antibodies, and that p53 protein misfolding impaired p53 DNA binding and transcription of target genes. (aacrjournals.org)
A focused analysis of transcription factors that directly interact with the predicted DENV-NS5 interacting proteins was performed, followed by the identification of downstream genes that are differentially expressed after dengue infection using previously published RNA-seq data. (springernature.com)

To investigate the efficiency of growth differentiation factor 9 and bone morphogenetic protein 15 during folliculogenesis in a dehydroepiandrosterone-induced mouse Polycystic ovary syndrome model. (balkanmedicaljournal.org)
Ovarian tissues were examined for growth differentiation factor 9 and bone morphogenetic protein 15 using immunofluorescent labelling and electron microscopic examinations. (balkanmedicaljournal.org)
These results suggest that the decrease in the growth differentiation factor 9 and bone morphogenetic protein 15 expression initiated at the primary follicle stage effect the follicle development and zona pellucida structure and may cause subfertility or infertility in Polycystic ovary syndrome. (balkanmedicaljournal.org)
Two related members of the TGFB superfamily are involved in the function and development of the ovary: Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) (7). (balkanmedicaljournal.org)

Stability of protein and nucleic acid structures. (pathfinderacademy.in)

Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. (edu.au)
We have employed a multidimensional approach involving electronic absorption, S and Cu K-edge XAS, EPR, and resonance Raman spectroscopies together with QM/MM computational analysis to examine the relationships between structure and molecular mechanism in this reaction. (stanford.edu)
Only a few follicles in the human ovary survive to complete the cytodifferentiation process, with 99.9% dying by a programmed cell death mechanism called apoptosis. (glowm.com)
Membrane structure and function: Structure of model membrane, lipid bilayer and membrane protein diffusion, osmosis, ion channels, active transport, ion pumps, mechanism of sorting and regulation of intracellular transport, electrical properties of membranes. (pathfinderacademy.in)

This technique has frequently been applied to animal tissue slices for the purpose to map proteins, peptides , lipids, sugars or small metabolites to find disease specific bio-markers or to study drag metabolism. (go.jp)
Due to their large surface area and ability to interact with proteins and peptides, graphene oxides offer valuable physiochemical and biological features for biomedical applications and have been successfully employed for optimizing scaffold architectures for a wide range of organs, from the skin to cardiac tissue. (mdpi.com)

cIAP1 (also named BIRC2) is the abbreviation for a human protein, cellular inhibitor of apoptosis protein-1. (wikipedia.org)
Using a cell apoptosis assay based on stimulation of a RANK:Fas fusion protein, and a cellular NF-kappaB signaling assay, we showed that R12-31 was agonist for both species. (cnrs.fr)
It is believed that NS2 plays a crucial role in major processes during the propagation of virus such as viral replication, assembly, regulation of cellular gene expression and in the induction of apoptosis. (ijbbb.org)
β-Catenin is a fascinating protein with many important cellular and developmental functions. (chemdiv.com)
β -catenin has many binding partners that mediate a diverse set of cellular functions, and the protein probably acts as a 'hub' on which many cellular signaling networks impinge. (chemdiv.com)
Dynamic cellular events beyond genetic encodings, such as epigenetics, and intermolecular protein interaction, play critical roles in dictating cellular functions. (go.jp)
PrP C , the cellular isoform of the prion protein, serves to transduce the neurotoxic effects of PrP Sc , the infectious isoform, but how this occurs is mysterious. (elifesciences.org)
These diseases are caused by refolding of the cellular prion protein (PrP C ) into an infectious isoform (PrP Sc ) that catalytically templates its abnormal conformation onto additional molecules of PrP C ( Prusiner, 1998 ). (elifesciences.org)
Bacteria are simple cells with simple organization of cellular structure and limited compartmentalization as compared to eukaryotes. (easyreport.in)

B ) Schematic representation of the p53 3D structure with the GOF mutation sites shown (purple). (encyclopedia.pub)
Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. (lookformedical.com)
In melanoma, i have focused in acral lentiginous melanoma for which we described KIT mutation and protein expression status in a large series of cases and described TERT amplification in progression to metastasis. (mdanderson.org)

15 The dynamic addition and removal of O-GlcNAc has been described for multiple cytoplasmic and nuclear proteins and it affects the function of various signaling molecules and transcription factors. (nature.com)

The p53 protein, to exert its function, binds in a sequence-specific manner to the DNA-binding sites by forming a tetramer, via four self-assembling p53 molecules, which are stabilized by protein-protein and base-stacking interactions [ 3 ] . (encyclopedia.pub)
eIF4B and PABP also bind to a site within the central region of eIF4G that partially overlaps the HEAT-1/eIF4G-MIG but they do not bind the HEAT-2/eIF4G-MA3 domain [ 9 ], demonstrating the functional diversity of the HEAT-1/eIF4G-MIG and HEAT-2/eIF4G-MA3 domains in their interactions with partner proteins. (biomedcentral.com)
The non-structural protein 5 (NS5) of dengue virus may be involved in host-pathogen interactions in addition to its core, essential functions - replicating and capping the viral RNA. (springernature.com)
Given these antecedents, it was tempting to for us to make an attempt to computationally predict interactions with human proteins that could form the basis of testable hypotheses leading to a better understanding of the mechanisms underlying observed immunological effects of dengue infection. (springernature.com)
Internal signals producing apoptosis depend on interactions of several proteins and may serve to protect the organism from cancer by killing cells that have pre-cancerous changes. (agemed.org)

The T-cell immunoglobulin domain and mucin domain (TIM) family, including TIM-1, TIM-2, TIM-3, and TIM-4, is a relatively newly described group of molecules with a conserved structure and important immunological functions, including T-cell activation, induction of T-cell apoptosis and T-cell tolerance, and the clearance of apoptotic cells. (nih.gov)

Mutations on the gene that encodes cIAP1 are related to hemorrhage and vascular regression because of the defects it represents on the endothelial cell survival and the modification of apoptosis. (wikipedia.org)
In this study, the sp2 gene was cloned and expressed in Escherichia coli to produce a 6xHis-tagged fusion protein, which was then used to generate a polyclonal antibody. (hindawi.com)
We now know those structures are very relevant to many critical biological processes like gene regulation, expression of telomerase and telomere maintenance, understanding of growth/oncogenes like C-myc, understanding of organismic development, comprehension of certain enigmatic diseases like ALS and possible new cancer treatments. (anti-agingfirewalls.com)
Among the various genetic metabolic disorders, Angelman syndrome (AS) has attracted considerable attention due to the abnormal expression of the ubiquitin-protein ligase E3A (UBE3A) gene ( 1 ). (spandidos-publications.com)
The human UBE3A gene encodes an E3 ubiquitin ligase, which exhibits three known protein subtypes ( 1 , 8 ). (spandidos-publications.com)
The roles of b-catenin are 'classically' defined: as an adhesion protein and as a signaling protein, transducing extracellular signals to the nucleus to modify gene expression. (chemdiv.com)
In this report antiviral effects of IFN- α 2b on translation were examined in a hepatic cell line using chimeric clones of internal ribosome entry site (IRES) sequences from six different HCV genotypes and the green fluorescence protein (GFP) gene. (microbiologyresearch.org)
Polycomb Group (PcG) proteins are a family of protein complex that regulate gene expression, especially repressing gene transcription [ 1 ]. (hindawi.com)
As one of the two distinct complexes, namely, Polycomb Repressive Complex 1 (PRC1) and PRC2, PRC2 mediates gene silencing by modulating chromatin structure [ 2 ]. (hindawi.com)
Alternative splicing of gene can generate multiple transcripts and proteins to regulate tissue and organ development [ 17 ]. (hindawi.com)

The activation of this pathway stops the noncanonical one and simultaneously the apoptosis. (wikipedia.org)
Compounds 1 and 2 but not 3 induced apoptosis through the mitochondrial pathway as suggested from the relative p53, caspase3 and bcl2 mRNA levels measured by real-time quantitative PCR analysis. (rsc.org)
The appearance of a unique form of PDCD4 in plants correlates with the appearance of components of the ethylene signaling pathway, suggesting that it may represent the adaptation of an existing protein involved in programmed cell death to one that functions in abiotic stress responses through hormone signaling. (biomedcentral.com)

The expressed protein in Escherichia coli was used to generate polyclonal antibodies. (hindawi.com)
Antibodies can be found on the surface of lymphocytes as an integral part of the cell membrane protein or can be freely circulating in the blood or be part of one of the body's gland secretion. (medscape.com)
Antibodies belong to immunoglobulin family of protein and have 5 isotypes (G, A, M, E, D) with further subclasses of G and A. The classes are differentiated with the characteristics of the Ig heavy chain of the antibody. (medscape.com)

G-quadruplexes are secondary semi-stable folded structures found in our DNA and RNA which tend to assemble around guanine-rich sequences in the presence of cation molecules like potassium. (anti-agingfirewalls.com)
Bases These are molecules with one or two nitrogen-containing ring structures. (agemed.org)
Structure of atoms, molecules and chemical bonds. (pathfinderacademy.in)
These may be different molecules within the cells like proteins, polysaccharides, or nucleoproteins and may also be the whole cell, like a tumor cell or organisms like bacteria, viruses, fungi, parasites, or agents containing genetic material such as nucleic acids or lipids. (medscape.com)

During apoptosis, Bax undergoes a conformational change involving NH 2 -terminal exposure and translocates to mitochondria to release apoptogenic factors. (rupress.org)

Abstract -Hepatitis C virus (HCV) nonstructural protein 2 (NS2) is a transmembranal protein with a hydrophobic amino-terminal subdomain containing up to three putative transmembrane segments and a carboxyterminal cytoplasmic domain. (ijbbb.org)

Additional studies have also shown that hemolymph from the silkworm ( Bombyx mori ) can inhibit insect and mammalian cell apoptosis that is induced by viruses and several chemical inducers, such as staurosporine, camptothecin, and actinomycin D [ 6 - 8 ]. (hindawi.com)
imd encodes a protein with a death domain similar to that of mammalian RIP (receptor interacting protein), a protein that plays a role in both NF-kappaB activation and apoptosis. (cnrs.fr)

article{georgel_drosophila_2001, title = {Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis}, author = {Philippe Georgel and S Naitza and Christine Kappler and Dominique Ferrandon and Daniel Zachary and C Swimmer and C Kopczynski and G Duyk and Jean-Marc Reichhart and Jules A Hoffmann}, issn = {1534-5807}, year = {2001}, date = {2001-10-01}, journal = {Dev. (cnrs.fr)
TIM-3, expressed on T cells and dendritic cells, regulates T-cell apoptosis and immune tolerance. (nih.gov)

cIAP1 is recruited to TNF receptor complexes where they support cell survival through NF-κB activation while suppressing apoptosis by preventing caspase activation. (wikipedia.org)
Organic solvent-induced proximal tubular cell apoptosis via caspase-9 activation. (cdc.gov)

The molecular weight of proteins were 102, 88 and 80 kDa, so they were named α, β and γ-catenin. (chemdiv.com)

cIAP1 is an inhibitor of apoptosis protein. (wikipedia.org)
PFI-1, a highly selective protein interaction inhibitor, targeting BET Bromodomains. (ox.ac.uk)
Cocrystal structures showed that PFI-1 acts as an acetyl-lysine (Kac) mimetic inhibitor efficiently occupying the Kac binding site in BRD4 and BRD2. (ox.ac.uk)

A terminal section of a chromosome which has a specialized structure and which is involved in chromosomal replication and stability. (lookformedical.com)
This review critically focuses on opportunities to employ protein-graphene oxide structures either as nanocomposites or as biocomplexes and highlights the effects of carbonaceous nanostructures on protein conformation and structural stability for applications in tissue engineering and regenerative medicine. (mdpi.com)
One specific RNA structure, G-quadruplexes (G4s), possess various roles in viruses and all domains of life, including transcription and translation regulation and genome stability, and serves as nucleation points for RNA liquid-liquid phase separation. (bvsalud.org)

Taken at face value, senile cataract is intimately associated with the increased risk of oxidative stress, which levies irrevocable changes in the lenticular proteins that impel the lens epithelial cells to the apoptotic phase. (molvis.org)

Following transcription and processing of an mRNA, the ribosome is responsible for performing protein synthesis. (biomedcentral.com)
The signal transducer and activator of transcription 5A (STAT5A) and STAT5B transcription factors have a conserved functional domain structure organized in N-terminal oligomerization, Coiled-coil, DNA-binding, Linker, SH2 and C-terminal transactivation domain. (nature.com)
18 Both enzymes, OGT and OGA as well as multiple O-GlcNAcylated proteins are enriched at sites of active transcription in human cells. (nature.com)

cIAP1 is a multi-functional protein which can be found in the cytoplasm of cells and in the nucleus of tumor cells. (wikipedia.org)
The programmed cell death 4 (PDCD4) protein is induced in animals during apoptosis and functions to inhibit translation and tumor promoter-induced neoplastic transformation. (biomedcentral.com)

Signals to trigger apoptosis may come from within the cell or from outside, by stimulating suicide receptors in the cell's external membrane. (agemed.org)

The proteolysis of pol η was found to occur at position 465, leading to a catalytically active truncated protein containing the PCNA-interacting motif PIP1. (cnrs.fr)
Cite:Sadia Anjum, Faryal Mahwish, Tahir Ahmad, and Muhammad Sohail Afzal, 'Mutational and Structural Analysis of HCV Non Structural Protein 2 (NS2) Revealed Genotype Specific Motif in TMD3 of the Protein,' International Journal of Bioscience, Biochemistry and Bioinformatics vol. 3, no. 4, pp. 384-386, 2013. (ijbbb.org)

These data raise the possibility that antibacterial response and apoptosis share common control elements in Drosophila. (cnrs.fr)
ROS have antibacterial effects mainly attributed to DNA and protein damage by the Fenton reaction. (easyreport.in)

However, studies investigating the roles of GDF9 and BMP15 proteins through the stages of folliculogenesis in the pathogenesis of PCOS do not currently exist. (balkanmedicaljournal.org)

In an important model of premature aging, Werner's Syndrome, the genetic problem seems to be lack of a helicase protein that can unwind G-quadruplexes. (anti-agingfirewalls.com)
Angelman syndrome (AS) is an autosomal dominant neurodevelopmental genetic disease with maternal imprint, which is associated with the presence of the abnormal chromosome 15q11‑q13, and the loss of maternal specific expression of ubiquitin‑protein ligase E3A (UBE3A). (spandidos-publications.com)

BET proteins are recruited on transcriptionally active chromatin via their two N-terminal bromodomains (BRD), a protein interaction module that specifically recognizes acetylated lysine residues in histones H3 and H4. (ox.ac.uk)
It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 1 in that it contains basic N-terminal amino acid residues. (lookformedical.com)
OGT transfers O-GlcNAc moieties from UDP-GlcNAc to serine and threonine residues of proteins and O-GlcNAcase (OGA) catalyzes the opposite reaction to remove O-GlcNAc. (nature.com)

In healthy cells the protein is usually found in the nucleus. (wikipedia.org)
When a cell is tumorous it does not cease to proliferate inhibiting the apoptosis, as a result, in cancerous cells cIAP1 is rarely located in the cytoplasm. (wikipedia.org)
A single-stranded DNA-binding protein that is found in EUKARYOTIC CELLS. (lookformedical.com)
It had been shown that certain altered PrP proteins caused the death of brain cells by allowing excessive electrical charges to cross the membranes of the cell. (elifesciences.org)
This process gets rid of unneeded cells and is particularly important for "sculpting" tissue and organ structure during development of the embryo (or larval metamorphosis in insects), but may occur at any time even in adult cells when a tissue needs to be remodeled. (agemed.org)

These unusual DNA structures play critical roles in regulation of very basic biological functions and are integral part of the complex regulatory systems of living beings. (anti-agingfirewalls.com)
It is currently unknown if this structure is conserved and maintained in a large ZIKV RNA transcript and its specific roles in viral replication. (bvsalud.org)
The discovery that dengue virus NS5 protein (DENV-NS5) can also localize to the nucleus has resulted in renewed interest in its potential roles at the host-virus interface. (springernature.com)

The APC protein, which comprises of 2843 amino acids, plays an important role in the β-catenin nuclear localization ( 8 ). (spandidos-publications.com)

This library represents a selection of drug-like compounds aimed at modulating protein-protein interaction (PPI) of β-catenin with different proteins involved in significant physiological processes. (chemdiv.com)

Although eIF4A is an ATP-dependent RNA helicase that binds the MA3 domain of eIF4G to promote translation initiation, binding of eIF4A to the MA3 domains of PDCD4 inhibits protein synthesis. (biomedcentral.com)
This paper aims to provide a comprehensive overview of the synthesis, chemical structure, biological activity, and potential applications of this compound. (evitachem.com)

However, when the cell is apoptotic nuclear export of cIAP1 is induced provoking an increase in the cytosolic concentration of the protein. (wikipedia.org)
Furthermore, both ELISA and flow cytometry results indicated that SP2 has anti-apoptotic effects on staurosporine-induced HUVEC apoptosis. (hindawi.com)
In addition, the expressed protein in the silkworm baculovirus system was used to study the anti-apoptotic effects of SP2 on human umbilical vein ECs (HUVECs) induced by peroxidation. (hindawi.com)

Studies show that when the protein is exposed to palmitate the concentration of cIAP1 decreases and, as a result, the apoptosis is no longer inhibited resulting in the death of the cell. (wikipedia.org)
Apoptosis Programmed Cell Death (PCD). (agemed.org)

At secondary structure level, a significant difference in the transmembrane segment 3 helix1 was noticed which is critically involve in viral assembly on the other hand the protease domain was fully conserved. (ijbbb.org)
A ) Simplified representation of the secondary structure showing domain organization of the human p53 protein (Uniprot #P04637). (encyclopedia.pub)
While eIF4E binds to the 5′-cap structure, eIF4A is an ATP-dependent RNA helicase that hydrolyzes ATP in order to unwind secondary structure present in the 5′-leader of an mRNA that would otherwise inhibit 40S subunit scanning during its search for the initiation codon [ 2 ]. (biomedcentral.com)
Secondary structure of the 5′ nontranslated regions of hepatitis C virus and pestivirus genomic RNAs. (microbiologyresearch.org)

Although first observed in the 19th century, their structures were not identified until in the 1960s and their presence and fuller relevance in the human genome only clarified in the last few years. (anti-agingfirewalls.com)
Novel therapeutics are an avenue of interest that could probe viral RNA-human protein communication to stop viral replication. (bvsalud.org)
Of the 42 human proteins predicted by both these methods, 34 are novel. (springernature.com)
Many research groups have sought to determine the human proteins that interact with NS5 using a variety of experimental approaches, which have been compiled in a review we published in 2021 7 . (springernature.com)

In this study, we have used two complementary computational approaches in parallel - one based on linear motifs (ELM) and another based on tertiary structure of the protein (DALI) - to predict the host proteins that DENV-NS5 might interact with. (springernature.com)

3D fluorescence studies showed that the HSA structure was altered at the secondary and tertiary levels upon binding with the complexes. (rsc.org)

The experiments showed that one end of the protein, called the N-terminus, is involved in the movement of electrical charges across the cell membrane and is able to cause cell degeneration. (elifesciences.org)

It belongs to the IAP family of proteins and therefore contains at least one BIR (baculoviral IAP repeat) domain. (wikipedia.org)

PDCD4 is composed of two MA3 domains that share similarity with the single MA3 domain present in the eukaryotic translation initiation factor (eIF) 4G, which serves as a scaffold protein to assemble several initiation factors needed for the recruitment of the 40S ribosomal subunit to an mRNA. (biomedcentral.com)
We review the principles of RNA structure conservation in viruses and discuss potential applications of xrRNAs in synthetic biology and future mRNA vaccines. (bvsalud.org)

Anatomy13

Organisms9

Diseases8

Chemicals and Drugs98

Analytical, Diagnostic and Therapeutic Techniques and Equipment38

Phenomena and Processes75

Disciplines and Occupations6

Technology, Industry, Agriculture2

Information Science20

Health Care6

Induces3

NECROSIS3

Signal transduc3

Proliferation5

Induce2

Quaternary structure1

Genes4

Differentiation4

Nucleic acid1

Mechanism4

Peptides2

Cellular9

Mutation3

Nuclear Proteins1

Interactions5

Induction1

Gene10

Pathway3

Antibodies3

Molecules4

Conformational1

Hydrophobic1

Mammalian2

Immune2

Activation2

Molecular1

Inhibitor3

Stability3

Epithelial cells1

Transcription3

Tumor2

Receptors1

Motif2

Antibacterial2

Pathogenesis1

Genetic2

Residues3

Cells5

Roles3

Amino acids1

Physiological1

Synthesis2

Apoptotic3

Death2

Secondary structure4

Human4

Interact1

Fluorescence1

Membrane1

Belongs1

MRNA2