MitochondriaMitochondria, LiverMitochondria, HeartApoptosisLiver DiseasesLiverCaspasesLiver NeoplasmsLiver TransplantationApoptosis Regulatory ProteinsCaspase 3Mitochondria, MuscleProto-Oncogene Proteins c-bcl-2Liver CirrhosisMitochondrial Proteinsbcl-2-Associated X ProteinCytochromes cMicrosomes, LiverInhibitor of Apoptosis ProteinsLiver RegenerationFatty LiverDNA FragmentationMitochondrial MembranesMembrane Potential, MitochondrialCell Line, TumorApoptosis Inducing FactorReactive Oxygen SpeciesMitochondrial SwellingIn Situ Nick-End LabelingCell SurvivalIntracellular MembranesCaspase 9Cells, CulturedSignal TransductionOxidative PhosphorylationX-Linked Inhibitor of Apoptosis ProteinCytochrome c GroupCaspase InhibitorsEnzyme ActivationOxygen ConsumptionCaspase 8Cell LineLiver Function TestsBlotting, WesternDrug-Induced Liver Injurybcl-X ProteinCell RespirationCASP8 and FADD-Like Apoptosis Regulating ProteinTumor Cells, CulturedMitochondrial Membrane Transport ProteinsTime FactorsDNA, MitochondrialMolecular Sequence DataTumor Suppressor Protein p53KineticsOxidative StressUncoupling AgentsRNA, MessengerFas Ligand ProteinElectron Transport Complex IVOxidation-ReductionMicroscopy, ElectronCarrier ProteinsAdenosine TriphosphateLiver Neoplasms, ExperimentalHepatocytesCell ProliferationAmino Acid Chloromethyl KetonesMembrane ProteinsCell DeathRats, WistarRats, Sprague-DawleyCysteine Proteinase InhibitorsDose-Response Relationship, DrugEnzyme InhibitorsProto-Oncogene ProteinsBH3 Interacting Domain Death Agonist ProteinAmino Acid SequenceFlow CytometryOligomycinsAnnexin A5TransfectionProtein TransportMalatesCytosolModels, BiologicalLiver CirculationRotenoneLiver ExtractsAntineoplastic AgentsBase SequenceCell NucleusPoly(ADP-ribose) PolymerasesNecrosisCalciumRats, Inbred StrainsCell CycleBiological TransportAntimycin AMutation