AnatomyOrganismsChemicals and DrugsPhenomena and Processes
Cell Wall SkeletonNocardiaCell WallApoptosis
NeuronsProliferationCycle arrestNecrosisPathwaysTissueInductionBonesProteinsTumor cellsTissuesVitroProgenitorTherapeuticReactiveInhibitionTurnoverCompoundsTypicallyGrowthTuberculosisControlStructuralInflammatoryHumanCulturesSurvivalCytoplasmicTranscription factorsInfectionsOrderShapeDivisionSideDevelopmentOptimalLineTreatmentBloodGenerationProceduresResponseProductionSignalDeathWaterBodyTimeLiveFreeFigureLayersSmall
Neurons3
  • your entire lifetime for your heart cells and the neurons in your cerebral cortex (brain! (zenandvitality.com)
  • Although some beneficial phytochemicals might function solely as antioxidants, it is becoming clear that many of the beneficial chemicals in vegetables, herbs, plants and fruits evolved as toxins (to dissuade insects and other predators) that, at subtoxic doses, activate adaptive cellular stress-response pathways in a variety of cells including neurons. (psychosocialsomatic.com)
  • In these ways, neurohormetic phytochemicals such as resveratrol, sulforaphanes and curcumin might protect neurons against injury and disease by stimulating the production of antioxidant enzymes, neurotrophic factors, protein chaperones and other proteins that help cells to withstand stress. (psychosocialsomatic.com)
Proliferation7
  • These mechanisms include the inhibition of T-cell proliferation and of macrophage microbicidal activity via diminished IFN-γ response. (wikipedia.org)
  • decreased cell proliferation, cell cycle arrest, and induction of apoptosis. (123dok.net)
  • It was suggested that HOXD9 contributes to both cell proliferation and/or cell survival. (123dok.net)
  • HOXD9 siRNA treatment of SK-MG-1 SP cells resulted in reduced cell proliferation. (123dok.net)
  • Conclusions: Our results suggest that HOXD9 may be a novel marker of GCSCs and cell proliferation and/or survival factor in gliomas and glioma cancer stem-like cells, and a potential therapeutic target. (123dok.net)
  • Homeobox proteins are master regulators of develop-ment and control many cellular processes, including proliferation, apoptosis, cell shape, and cell migration. (123dok.net)
  • Cell proliferation is important in maintaining healthy, vibrant skin. (tlsslim.com)
Cycle arrest2
  • PTOX prevents cell growth via polymerization of tubulin, leading to cell cycle arrest and suppression of the formation of the mitotic-spindles microtubules. (ac.ir)
  • Aloe emodin is also reported to induce cell cycle arrest and apoptosis [ 11 ]. (longdom.org)
Necrosis3
  • Increased production of mediators, such as interleukin (IL)‐8, tumour necrosis factor‐α (TNF‐α) and leukotriene B 4 , which both attract inflammatory cells and increase oxidant production by these cells, has been found. (ersjournals.com)
  • Necrosis - injury driven cell death which involves the cell bursting and spewing their contents creating a localized inflammatory response. (zenandvitality.com)
  • Death of cells can be either harsh or gentle to the extracellular environment termed necrosis or apoptosis, respectively. (co.ke)
Pathways2
  • This demonstrates one virulence-associated mechanism by which bacteria are able to up-regulate signaling pathways to control host cell apoptosis. (wikipedia.org)
  • Examples of such 'preconditioning' or 'neurohormesis' pathways include those involving cell-survival signaling kinases, the transcription factors NRF2 and CREB, and histone deacetylases of the sirtuin family. (psychosocialsomatic.com)
Tissue4
  • While sponges (with the exception of hexactinellids) lack tissue-layer organisation, they do possess diverse cell types with specific roles. (microbiologynote.com)
  • This rule-based approach involves studying bone mechanobiology at the cell scale and extrapolating this to millions of cells at the tissue scale to understand the pharmacokinetics of treatments and identify possible new therapies and approaches to patient-specific treatment. (sirop.org)
  • Loeys-Dietz syndrome (LDS) is a genetic condition affecting the connective tissue and involving multiple organ systems including the blood vessels, skeleton, eyes and skin. (rarediseases.org)
  • LDS is a disorder of connective tissue, so it affects the bones, ligaments, arterial walls, and skin most significantly. (rarediseases.org)
Induction1
  • Similarly studies with Emodin and Aloe emodin derivatives have also revealed greater therapeutic potential, DNA intercalation property, and reactive oxygen species generation and thereby induction of apoptosis in cancer cells [ 12 ]. (longdom.org)
Bones1
  • The constant turnover of cells all over the body results in your outer layer of skin being recycled every two weeks, your liver being completely replaced every year and a half, the bones of your skeleton being all "brand new" every decade or so. (zenandvitality.com)
Proteins2
  • Once produced within a cell, free radicals can damage a wide variety of cellular constituents, including proteins, lipids and DNA. (enzolifesciences.com)
  • Examples include finding proteins indicating cardiac problems or looking for circulating tumour cells that can indicate the spread of cancer. (50webs.com)
Tumor cells1
  • Moreover, further preclinical studies are warranted to explore the molecular mechanisms of these agents in treatment of cancer and their possible potential to overcome chemoresistance of tumor cells. (ac.ir)
Tissues1
  • Results: In this study, we found high expression of the HOXD9 gene transcript in glioma cell lines and human glioma tissues by quantitative real-time PCR. (123dok.net)
Vitro2
  • ManLAM has been shown to be an anti-inflammatory molecule that inhibits production of TNF-α and IL-12 production by human dendritic cells and human macrophages in vitro and to modulate M. tuberculosis-induced macrophage apoptosis via binding to host macrophage mannose receptors. (wikipedia.org)
  • Based on preclinical and in vitro studies of cell behaviour and cytokine reaction-diffusion and mechanical tests we have generated an in-house biofidelic agent-based model of the human skeleton and its response to diseases and their treatments. (sirop.org)
Progenitor2
  • This ancient biochemical progenitor of eukaryotic cells therefore gave birth to the cytoplasmic mevalonate machinery in plants and the 1-deoxy-D-xylulose pathway was later derived from the endosymbiotic cyano- bacteria. (tradingsignalsforex.com)
  • Finally, we cultured human glioma cancer stem cells (GCSCs) from patient specimens found with high expression of HOXD9 in GCSCs compared with normal astrocyte cells and neural stem/progenitor cells (NSPCs). (123dok.net)
Therapeutic1
  • Emodin and its derivatives are anthraquinone skeleton containing compounds having varied therapeutic applications ( Figure 1 ). (longdom.org)
Reactive2
  • Both reactive oxidant species from inhaled cigarette smoke and those endogenously formed by inflammatory cells constitute an increased intrapulmonary oxidant burden. (ersjournals.com)
  • Enzo Life Sciences ROS-ID® ROS/RNS detection kit is designed to directly monitor real time reactive oxygen and/or nitrogen species (ROS/RNS) production in live cells using fluorescence microscopy. (enzolifesciences.com)
Inhibition1
  • Properly designed drug delivery systems like liposomes and nanoparticles have been reported as efficient emodin carriers and to enhance emodin activity in cancer cell inhibition. (longdom.org)
Turnover1
  • [ 3 ] In fact, there is so much turnover that in 4 years, the skeleton of a young person will be completely new as compared with their skeleton today. (medscape.com)
Compounds2
  • HPLC separation of Rhubarb extract isolated five compounds with the anthroquinone skeleton among other compounds [ 1 ]. (longdom.org)
  • Based on the significant antibacterial activity, the sorting of bacterial cells against the compounds (MID6 and MID9) was analyzed by flow cytometry. (degruyter.com)
Typically1
  • Choanocytes or flagellated collar cells typically line the canal system's chambers. (microbiologynote.com)
Growth2
  • An extremely important zone in human development, the epiphyseal plate is responsible for longitudinal growth of the skeleton and therefore one's height and stature. (medscape.com)
  • These antioxidants are coupled with specific vitamins and minerals that are conducive to cell growth and division. (tlsslim.com)
Tuberculosis1
  • Computed tomography scan of a year-old woman with documented infectious ileitis secondary to tuberculosis and ileal wall thickening arrows. (ab-uebersetzer.com)
Control3
  • L-arginine-induced cells incubated with NO Scavenger (c-PTIO) demonstrate minimal red fluorescence comparable to control values. (enzolifesciences.com)
  • Pyocyanin-induced cells incubated with ROS Inhibitor (N-acetyl-L-cysteine) demonstrate minimal green or orange fluorescence signal comparable to control values. (enzolifesciences.com)
  • MID9 showed a moderate level of cell death compared to the control. (degruyter.com)
Structural1
  • Structural changes to essential components of the lung are caused by oxidative stress, contributing to irreversible damage of both parenchyma and airway walls. (ersjournals.com)
Inflammatory2
  • In addition to serving as a major cell wall component, it is thought to serve as a modulin with immunoregulatory and anti-inflammatory effects. (wikipedia.org)
  • The inflammatory process in patients with stable COPD is dominated by macrophages, CD8+ T‐lymphocytes and neutrophils, and to a lesser extent mast cells, in the bronchial submucosa and alveoli 5 . (ersjournals.com)
Human3
  • 1998. Protection of human upper respiratory tract cell lines against sulphur mustard toxicity by hexamethylenetetramine (HMT). (cdc.gov)
  • Functional analysis of HOXD9 in human gliomas and glioma cancer stem cells. (123dok.net)
  • The MTT assay was used to examine the cytotoxic effects of fungal taxol against the human liver cancer cell line HepG2. (degruyter.com)
Cultures1
  • Production of podophyllotoxin by plant cell cultures of Podophyllum hexandrum in bioreactor. (ac.ir)
Survival1
  • Dephosphorylated Bad serves as a pro-apoptotic protein and its activation allows for cell survival. (wikipedia.org)
Cytoplasmic1
  • Stained HeLa cells induced with L-arginine exhibit bright red fluorescence with a red punctuate cytoplasmic staining pattern. (enzolifesciences.com)
Transcription factors1
  • Background: HOX genes encode a family of homeodomain-containing transcription factors involved in the determination of cell fate and identity during embryonic development. (123dok.net)
Infections1
  • Ridding the body of toxins, removing mutated cells parts, eliminating infections and bacteria, and reducing inflammation are all the jobs of autophagy. (zenandvitality.com)
Order1
  • Apoptosis - cell suicide which is carefully controlled, programmed in advance, and allows full recycling of all cell components in order to support and maintain the organism (you! (zenandvitality.com)
Shape1
  • If uncorrected, craniosynostosis can lead to increased intracranial pressure (ICP) and abnormalities in the shape and symmetry of the craniofacial skeleton. (medscape.com)
Division1
Side1
  • The HOXD9 gene was highly expressed in a side population (SP) of SK-MG-1 cells that was previously identified as an enriched-cell fraction of glioma cancer stem-like cells. (123dok.net)
Development1
  • Animal Physiology-Cell, Artificial Intelligence and Signal and Image Processing, Cell Development (incl. (sirop.org)
Optimal2
  • This constant cellular renewal means that we benefit greatly from providing optimal cell conditions throughout our lifetime - not just when we are growing children. (zenandvitality.com)
  • This orderly death to a cell happens all over the body and is nature's way of keeping you in optimal condition. (zenandvitality.com)
Line1
  • The ROS-ID ® ROS/RNS detection kit is a member of the CELLESTIAL ® product line, reagents and assay kits comprising fluorescent molecular probes that have been extensively benchmarked for live cell analysis applications. (enzolifesciences.com)
Treatment2
  • This project aims to investigate bone's response to sclerostin antibody treatment and uncover the cellular mechanisms governing bone adaptation using single-cell mechanomics cluster analysis. (sirop.org)
  • A significant decrease (0.05-0.5 μM) was observed in the cell viability and IC 50 dosage was fixed as 0.25 μM after 24 h of treatment. (degruyter.com)
Blood2
  • HN - 2008 BX - Granulosa Cells, Cumulus MH - Coronary Sinus UI - D054326 MN - A07.231.908.194.500 MS - A short vein that collects about two thirds of the venous blood from the MYOCARDIUM and drains into the RIGHT ATRIUM. (bvsalud.org)
  • Clinically, systemic systolic blood pressure at or shortly after the aortic valve opens correlates with peak systolic wall stress and approximates afterload. (msdmanuals.com)
Generation1
  • Representative experiment demonstrating peroxynitrite and NO generation in HeLa cells using the ROS/RNS Detection Kit. (enzolifesciences.com)
Procedures1
  • ROS-ID ® ROS/RNS detection kit is used to stain HeLa cells using the procedures described in the user manual. (enzolifesciences.com)
Response1
  • Autophagy - partial cell rebirth where certain parts of the cell are renewed as a response to stressors such as nutrient and oxygen deprivation. (zenandvitality.com)
Production2
  • Co-culture of arbuscular mycorrhiza-like fungi (Piriformospora indica and Sebacina vermifera) with plant cells of Linum album for enhanced production of podophyllotoxins: a first report. (ac.ir)
  • Finally, as discussed in the above examples, bacteria that make their living by exploiting eukaryotic hosts have coupled production of the virulence factors necessary for a pathogenic lifestyle to their ability to detect changes in cell population density. (lihuadong.net)
Signal1
  • Stained HeLa cells induced with pyocyanin exhibit bright orange signal in the nucleus as well as bright green fluorescence in the cytoplasm, but no red signal specific for nitric oxide. (enzolifesciences.com)
Death1
  • Autophagy can help reduce the effects of aging but too much results in cell death. (zenandvitality.com)
Water2
  • Many pores in the body wall allow water to enter the spongocoel. (microbiologynote.com)
  • Nonetheless, sponges exhibit a variety of body morphologies, including differences in the size of the spongocoel, the number of osculi, and the location of the cells that filter food from the water. (microbiologynote.com)
Body1
  • Your body is made up of tens of trillions of cells - those numbers have 13 or more zeroes in them! (zenandvitality.com)
Time2
  • In pregnancy, to understand the place and importance of micronutrients or any nutrient, we must go back to the beginning-at the time when the sperm fertilizes the egg and implantation 5-6 days later into the uterine wall. (vitamindwiki.com)
  • It is determined by LV chamber pressure, radius, and wall thickness at the time the aortic valve opens. (msdmanuals.com)
Live3
Free1
Figure1
  • In due course, these depolarizations propagate to adjoining cells via hole junctions (Figure 4). (ehd.org)
Layers1
  • NMR is a archaeological protein which provides past, visual skeleton materials into the vast resources of layers in textual microscopy. (private-art.com)
Small1
  • There are two main subcategories of lung cancer: nonsmall cell lung cancer (NSCLC) and small cell lung cancer (SCLC). (hindawi.com)