ApoptosisCell SurvivalSurvival RateCaspasesApoptosis Regulatory ProteinsCaspase 3Proto-Oncogene Proteins c-bcl-2Signal TransductionCell Line, TumorInhibitor of Apoptosis ProteinsDisease-Free SurvivalIn Situ Nick-End LabelingDNA FragmentationCells, Culturedbcl-2-Associated X ProteinCell ProliferationSurvivalX-Linked Inhibitor of Apoptosis ProteinEnzyme Activationbcl-X ProteinSurvival AnalysisTime FactorsTumor Suppressor Protein p53Proto-Oncogene ProteinsCell LineTumor Cells, CulturedGraft SurvivalMitochondriaBlotting, WesternAntineoplastic AgentsCell DeathCaspase InhibitorsCaspase 9CASP8 and FADD-Like Apoptosis Regulating ProteinApoptosis Inducing FactorPhosphorylationProto-Oncogene Proteins c-aktRNA, Small InterferingCaspase 8Fas Ligand ProteinCell CycleTransfectionCytochromes cCell DivisionProtein-Serine-Threonine KinasesEnzyme InhibitorsMice, Inbred C57BLbcl-Associated Death ProteinMice, KnockoutPhosphatidylinositol 3-KinasesDose-Response Relationship, DrugAnnexin A5Flow CytometryDown-RegulationGene Expression Regulation, NeoplasticImmunohistochemistryNF-kappa BRNA, MessengerReverse Transcriptase Polymerase Chain ReactionUp-RegulationPoly(ADP-ribose) PolymerasesReactive Oxygen SpeciesAmino Acid Chloromethyl KetonesCysteine Proteinase InhibitorsTreatment OutcomeDNA DamageRNA InterferenceTumor Necrosis Factor-alphaMutationGene Expression RegulationJurkat CellsGenes, bcl-2Models, BiologicalOxidative StressDNA-Binding ProteinsCell DifferentiationBreast NeoplasmsAutophagyMice, TransgenicCaspase 7TNF-Related Apoptosis-Inducing LigandMembrane Potential, MitochondrialKaplan-Meier EstimateNeoplasm ProteinsMitogen-Activated Protein KinasesMyeloid Cell Leukemia Sequence 1 ProteinMembrane ProteinsNeoplasmsNecrosisCarrier ProteinsDrug Resistance, NeoplasmGene ExpressionMembrane GlycoproteinsLung NeoplasmsHL-60 CellsMice, NudeRetrospective StudiesHeLa CellsDisease Models, AnimalTranscription Factors