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  • oxidative
  • The manganese superoxide dismutase (MnSOD), located in the mitochondria, is a major antioxidant enzyme that plays an important role in protecting cells from oxidative damage. (hku.hk)
  • One of the most common of these hypotheses may be the antioxidant hypothesis, that is, since oxidative modification of LDL is important, and possibly obligatory, in the pathogenesis of atherosclerotic lesions, antioxidative vitamins are protective against cardiovascular disease through their defensive effect on LDL oxidation. (ahajournals.org)
  • Burned patients because of their increased oxidative stress have severely depleted vitamin E, which is a dietary antioxidant. (clinicaltrials.gov)

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  • inhibit
  • Antioxidants such as α-tocopherol, which partition into the lipid compartment of cells, or N-acetylcysteine, a free radical scavenger that partitions into the aqueous phase of the cytosol, can delay or inhibit apoptosis (24,25). (redorbit.com)
  • Thus, it is reasonable to suggest that removal of antioxidants from the diet might enhance apoptosis, and thereby inhibit tumor growth. (redorbit.com)
  • stroke
  • Tirilazad is an antioxidant steroid derivative that inhibits the lipid peroxidation that is believed to play a key role in neuronal death in stroke and head injury. (wikipedia.org)
  • Similarly, the designed antioxidant NXY-059 exhibited efficacy in animal models, but failed to improve stroke outcomes in a clinical trial. (wikipedia.org)
  • physiological
  • Accordingly, regulatory agencies like the Food and Drug Administration of the United States and the European Food Safety Authority (EFSA) have published guidance disallowing food product labels to claim an inferred antioxidant benefit when no such physiological evidence exists. (wikipedia.org)
  • Immunological stress by over-supplementation of antioxidants facilitates adverse health effects specifically including allergies, asthma, and physiological alterations (especially of the skin). (wikipedia.org)
  • diseases
  • Although dietary antioxidants have been investigated for potential effects on neurodegenerative diseases such as Alzheimer's disease , Parkinson's disease , and amyotrophic lateral sclerosis , these studies have been inconclusive. (wikipedia.org)
  • Several antioxidants are currently used to treat diseases. (news-medical.net)
  • Individuals with neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease also benefit to a certain extent from the use of antioxidants. (news-medical.net)
  • The net result: over-supplementation of antioxidants are a direct, underlying cause of allergenic diseases and skin alterations, spurring signs (objective indications) and symptoms (subjective states) of localized and disseminated medical conditions. (wikipedia.org)
  • effects
  • another antioxidant I try to implement as much as possible is catechins (the active extract in green tea), as the research I have (so far) has only pointed towards positive effects and health benefits both in terms of immunology, decreased cancer risk and increased system abilities. (hubpages.com)
  • Antioxidants also help slow down the aging process, which can have immense effects on your skin health. (mercola.com)
  • Thus
  • Thus, though early administration of antioxidants may prevent the initiation and progression of cancer by quenching the action of potentially mutagenic reactive free radicals, administration of antioxidants subsequent to a mutagenic event may effectively intercept free radicals that are critical in promoting apoptosis. (redorbit.com)
  • Antioxidants attenuate the Th-1 immune response, responsible for eliminating bacterial and fungal threats, while the Th-2 immune response compensates for a weak Th-1 response by increasing its own responders, which may be not only ineffective, but overall destructive to healthy surrounding tissues, thus harmful. (wikipedia.org)
  • unlikely
  • Red wine is high in total polyphenol count which supplies antioxidant quality which is unlikely to be conserved following digestion (see section below). (wikipedia.org)
  • biological
  • citation needed] The polyphenol content of wines is usually evaluated by the Folin-Ciocalteu reagent which correlates well with alternative chemical and biological procedures for determining antioxidant potential. (wikipedia.org)
  • Several complex biological free-radical collection systems already exist for the purpose of scavenging, which normally, do not require augmentation by supplementation of antioxidants to function nominally. (wikipedia.org)
  • good
  • Numerous studies have confirmed the benefits of antioxidants and the role they play in maintaining good health and reducing your risk of heart disease, Parkinson's, Alzheimer's, and cancer. (mercola.com)
  • Research
  • As per a report by Transparency Market Research, the global market for antioxidants will likely reach a value of US$3.11 bn by 2020 in terms of revenue. (transparencymarketresearch.com)
  • Most people know the word "antioxidant" but new research from the Dole Nutrition Institute has uncovered that we may not know exactly how they work. (dole.com)
  • cancer
  • however, by inhibiting apoptosis, these same antioxidants may exert a cancer-promoting effect in cancer patients and in individuals with precancerous DNA changes. (redorbit.com)