AntimetabolitesAntimetaboliteRheumatoid arthritisDMARDImmunosuppressiveMethotrexateInhibitorsAnti-inflammatoryPotent2021BiologicChemicalsRheumaticInhibitsGeneralReceptorSpecificAntimetaboliteAnalgesicImmunosuppressive agentAnthracyclineAntibioticAntiparasiticVitroTherapeuticInflammationReceptorDrugsProstaglandinChemotherapeutic agentsAnalgesicsVaried metabolicAnti-InflamLeflunomide
Antimetabolites1
- It belongs to a class of drugs known as antimetabolites and is considered as a cytotoxic chemotherapy agent. (gminsights.com)
Antimetabolite2
- An antineoplastic antimetabolite with immunosuppressant properties. (illumina.com)
- Azacitidine is an antimetabolite antineoplastic with general properties similar to those of cytarabine. (pocketdrugguide.com)
Rheumatoid arthritis1
- Actarit is a disease-modifying antirheumatic drug (DMARD) developed in Japan for use in rheumatoid arthritis. (wikipedia.org)
DMARD1
- It is classified as a disease-modifying anti-rheumatic drug (DMARD) when used for autoimmune diseases and as a chemotherapeutic agent for cancer treatment. (gminsights.com)
Immunosuppressive4
- Most patients are treated with oral prednisone, with or without a cytotoxic/immunosuppressive agent, such as methotrexate, cyclophosphamide, or chlorambucil, or a tumor necrosis factor (TNF)-alpha antagonist. (medscape.com)
- Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. (nih.gov)
- Cyclophosphamide, together with its active metabolites, aldophosphamide, acrolein and nitrogenated mustard, is an antineoplastic from the group of nitrogen mustards with very marked immunosuppressive properties. (e-lactancia.org)
- The concomitant use of other immunosuppressive medications with synergistic adverse immunologic effects - In addition, the use of multiple biologic agents is rarely studied formally but is becoming increasingly common in clinical practice. (medilib.ir)
Methotrexate1
- Methotrexate is an antineoplastic anti-metabolite. (illumina.com)
Inhibitors1
- See "Overview of biologic agents in the rheumatic diseases" and "Principles of cancer immunotherapy", section on 'Checkpoint inhibitor immunotherapy' and "Toxicities associated with immune checkpoint inhibitors" . (medilib.ir)
Anti-inflammatory2
- These agents have anti-inflammatory properties and cause profound and varied metabolic effects. (medscape.com)
- These agents have analgesic, anti-inflammatory, and antipyretic activities. (medscape.com)
Potent2
- Prevalence may be decreasing with the advent of more potent antirheumatic agents. (medscape.com)
- Imidazole-pyridine hybrids as potent anti-cancer agents. (jefferson.edu)
20211
- Objetivo: Describir el uso de TCZ en pacientes adultos hospitalizados por COVID-19 en Hospital María Especialidades Pediátricas (HMEP), agosto 2020-marzo 2021. (bvsalud.org)
Biologic2
- OVERVIEW - Biologic therapies that can increase the risk of infectious diseases include antithymocyte globulin, monoclonal antibodies to T and B cells, anticytokine therapies, agents that disrupt T cell costimulation signals, and agents that interfere with T cell inhibitory (checkpoint) signals. (medilib.ir)
- Factors that increase the risk of infectious complications - With any biologic agent, the likelihood of clinically significant infection primarily depends upon the actions of the drug in question, its dose, and the duration of treatment. (medilib.ir)
Chemicals1
- The medical treatments available to treat sun-induced skin damage include destruction of the lesions with cryogens (freezing), electrodessication (burning), curettage (cutting), chemical peeling agents and medical therapy with chemicals such as 5-Flurouracil and retinoids. (herbs.org.nz)
Rheumatic2
- These agents selectively target cells and pathways of the immune system to achieve specific therapeutic effects and are used primarily in the treatment of rheumatic, inflammatory, and malignant diseases. (medilib.ir)
- Overview discussions of the use of these agents in rheumatic disorders and oncologic diseases are found separately. (medilib.ir)
Inhibits1
- This agent inhibits prostaglandin synthesis. (medscape.com)
General1
- In general, infections with common bacterial pathogens may become more frequent with agents targeting the B cell system, whereas intracellular pathogens, including opportunistic microbes, are often seen in treatment that is more focused on T cell immunity. (medilib.ir)
Receptor1
- El Tocilizumab (TCZ), un anticuerpo monoclonal humanizado que actúa como antagonista del receptor de Interleucina 6 (IL-6), ha sido utilizado en enfermedades inmunológicas y en pacientes críticos por COVID-19. (bvsalud.org)
Specific1
- The impact in terms of altering host defense and infectious susceptibility varies depending on the specific agent(s) used. (medilib.ir)
Antimetabolite2
- Methotrexate (MTX) is an antineoplastic antimetabolite and folic acid analogue and antagonist with antineoplastic and immunosuppressive properties from interfering with the synthesis and cellular replication of DNA. (e-lactancia.org)
- With the exception of rituximab (HR 1.72, 1.10-2.69), there was no increased risk of mechanical ventilation or in-hospital death for the rheumatological, antineoplastic, or antimetabolite therapies examined. (covidreference.com)
Analgesic1
- These agents have analgesic, anti-inflammatory, and antipyretic activities. (medscape.com)
Immunosuppressive agent1
- Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. (nih.gov)
Anthracycline1
- Aclarubicm is an anthracycline antibiotic with antineoplastic actions similar to those of the other anthracyclines (see Doxorubicin Hydrochloride), although it inhibits RNA synthesis more strongly than DNA synthesis. (pocketdrugguide.com)
Antibiotic1
- Some chemotherapeutic agents with antibiotic effects can alter the composition of the microbiota (bacterial cluster or bacterial flora) of the milk and the concentration of some of its components (Urbaniak 2014) . (e-lactancia.org)
Antiparasitic3
- To date, several current studies have provided supporting evidence on the significant antiseptic, anesthetic, and antitumor properties of myrrh, and more clinical trials are yet to validate the role of myrrh as an antineoplastic and antiparasitic agent and as an adjunct to wound healing. (herbshealthhappiness.com)
- Between 2000 and 2005, twenty new antiparasitic agents were developed or in development. (mdwiki.org)
- Nitazoxanide [NTZ: 2-acetyloxy-N-(5-nitro-2-thiazolyl)benzamide] is a thiazolide antiparasitic agent with excellent activity against a wide variety of protozoa and helminths. (mdwiki.org)
Vitro2
- Although NIOSH hazardous drug evaluation includes consideration of carcinogenicity and geno- toxicity, this evaluation is tailored to identify and evaluate data from human toxicity profiles, animal studies and in vitro studies unique to evaluating therapeutic agents. (cdc.gov)
- 1. In vitro antineoplastic effects of auranofin in canine lymphoma cells. (nih.gov)
Therapeutic1
- The systemic organ-specific therapeutic approach may follow, as a general rule, the sequential (or combined) use of glucocorticoids, immunosuppressive agents, and biologics. (medscape.com)
Inflammation2
- This agent decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reducing capillary permeability. (medscape.com)
- Current drug therapies for rheumatoid arthritis (RA), including nonsteroidal anti-inflammatory drugs and disease-modifying antirheumatic drugs, help control inflammation but can cause significant toxicity. (nih.gov)
Receptor1
- Pfizer has an agent in preclinical development (JO-2871, a sigma opioid receptor modulator and novel antidiarrheal), while both GSK (UK-321130, a delta opioid antagonist) and Eli Lilly (alvimopan, a mu receptor antagonist) have compounds in Phase I development for irritable bowel syndrome. (pocketdrugguide.com)
Drugs1
- Early concerns about occupational exposure to provides some guidance on engineering controls antineoplastic drugs first appeared in the 1970s. (cdc.gov)
Prostaglandin1
- This agent inhibits prostaglandin synthesis. (medscape.com)
Chemotherapeutic agents1
- Administer melphalan under the supervision of a qualified health care provider experienced in the use of cancer chemotherapeutic agents. (medicine.com)
Analgesics1
- Consider analgesics or other pain-modifying agents for musculoskeletal pain, considering the balance between potential benefits and side-effects. (medscape.com)
Varied metabolic1
- These agents have anti-inflammatory properties and cause profound and varied metabolic effects. (medscape.com)
Anti-Inflam3
- Anti-Inflammatory Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (wakehealth.edu)
- This graph shows the total number of publications written about "Anti-Inflammatory Agents" by people in this website by year, and whether "Anti-Inflammatory Agents" was a major or minor topic of these publications. (wakehealth.edu)
- Below are the most recent publications written about "Anti-Inflammatory Agents" by people in Profiles. (wakehealth.edu)
Leflunomide1
- Leflunomide is an agent that affects the inflammatory process, particularly in RA. (nih.gov)