RauwolfiaAnti-hypertensiveHypertensionAntipsychoticMedicationGuanethidineSpironolactoneSarpagandhaNorepinephrinePotentiateRescinnamineDepletesCatecholamineClonidineHydrALAZINEAntidepressantsSedativePeripheralAgentsAgentDepressionDrugCompoundIncreasesWithdrawalTherapyTreatmentAdultLevelsHighPropertyMedicineProperties
Rauwolfia10
- reserpine , drug derived from the roots of certain species of the tropical plant Rauwolfia . (britannica.com)
- Reserpine, isolated in 1952, was the first of many Rauwolfia alkaloids found in the crude drug. (britannica.com)
- Reserpine is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. (immunoportal.com)
- Reserpine is derived from Rauwolfia serpentina, and was commonly used as an antihypertensive agent in the 1950s 12 . (drugbank.com)
- Reserpine is in a class of medications called rauwolfia alkaloids. (drugbank.com)
- Reserpine, an active compound found in Rauwolfia, renders the herb its antihypertensive property. (kayawell.com)
- The Rauwolfia alkaloid, reserpine, was soon found to be a powerful tranquilizing agent and was identified as a valuable addition to psychiatric therapy. (laskerfoundation.org)
- The main active constituent in Rauwolfia Serpentina is Reserpine, which is well-known for its antipsychotic and antihypertensive action. (yourmedkart.com)
- Reserpine present in Rauwolfia removes the store of noradrenaline from artery walls which relaxes the blood vessels which makes the blood flow more easily slowering the heart rate leading to reduction of blood pressure. (yourmedkart.com)
- Reserpine, an alkaloid in Rauwolfia reduces BP by decreasing the activity of central and peripheral noradrenergic neurons. (hempstreet.in)
Anti-hypertensive3
- A number of reports of substance-induced mood disorders (SIMDs) have emerged since the 1950s, when psychiatric complications were described in patients treated with the anti-hypertensive reserpine. (medscape.com)
- In their 2009 book, "Medicinal Plants of the World," botanist Ben-Erik van Wyk and biologist Michael Wink say that Indian snakeroot is anti-hypertensive because reserpine inhibits the re-uptake of norepinephrine, causing its depletion by enzymes 2 . (healthfully.com)
- 1) Alpha-asarone is similar in structure to reserpine, a drug used as anti-hypertensive and sedative, and gives the same effects. (dhpforum.nl)
Hypertension9
- Reserpine is sometimes used in treating hypertension, though newer antihypertensive drugs with fewer central nervous system side effects are the preferred treatment . (britannica.com)
- Reserpine is infrequently used alone for the treatment of hypertension due to possible side effects. (syrianclinic.com)
- Reserpine is an adrenergic blocking agent used to treat mild to moderate hypertension via the disruption of norepinephrine vesicular storage. (drugbank.com)
- At its meeting in 2002, the Committee recommended that the section 12.3 of the Model List (Antihypertensive medicines) be reviewed in the light of new clinical guidelines for the treatment of hypertension that were being prepared jointly by WHO and the International Society for Hypertension (ISH) (1). (essentialmeds.org)
- The Committee assessed all seven antihypertensive medicines currently included in section 12.3 of the Model List in the light of the draft statement on the management of hypertension. (essentialmeds.org)
- The Committee noted that the role of the older medicines for the treatment of essential hypertension (i.e. reserpine, hydralazine and methyldopa) is now considered to be questionable. (essentialmeds.org)
- On the basis of the evidence before it, the Committee recommended that reserpine and hydralazine be deleted from the Model List for the treatment of essential hypertension on the grounds of the lack of evidence of long-term effects on mortality and morbidity and the availability of better and safer alternatives. (essentialmeds.org)
- For studies on the use of reserpine in the treatment of hypertension. (laskerfoundation.org)
- Reserpine is a catecholamine -depleting sympatholytic that is FDA approved for the {{{indicationType}}} of mild essential hypertension . (wikidoc.org)
Antipsychotic2
- It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use. (immunoportal.com)
- Overall, Sarpagandha churna and vati have been used in traditional medicine to treat various health conditions due to its antihypertensive, anxiolytic, antipsychotic, and digestive properties. (aarogyacbd.com)
Medication3
- Reserpine used in conjunction with other psychotropic medication may be considered in the treatment of refractory mania, but controlled trials are necessary to support our finding more generally. (sajp.org.za)
- relief of symptoms in agitated psychotic states (e.g., schizophrenia ), primarily in those individuals unable to tolerate phenothiazine derivatives or in those who also require antihypertensive medication. (wikidoc.org)
- This medication has antihypertensive, antianginal and antiarrhythmic action. (medicatione.com)
Guanethidine2
- Traditional blood pressure lowering medications, like reserpine and guanethidine, often cause sexual dysfunction in men, along with dizziness and depression, and for this reason many doctors have moved away from them. (healthyplace.com)
- Reserpine depletes brain (depression) and peripheral (PPH) noradrenaline (NA) storage sites, guanethidine depleted NA storage via blockade of reuptake 14 . (drugbank.com)
Spironolactone1
- Reduces the effectiveness of spironolactone, Furosemide, antihypertensive drugs, anti-gout remedies that promote the excretion of uric acid. (bestpharmbuy.com)
Sarpagandha2
- In Ayurvedic medicine, under the name sarpagandha, it has been known as an effective antihypertensive (agent: Reserpine) and as an anxiolytic remedy for centuries and is also used by Indian yogis for promoting meditation. (magicgardenseeds.com)
- Sarpagandha churna and vati are known to have antihypertensive properties, which help in regulating blood pressure levels. (aarogyacbd.com)
Norepinephrine2
- Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. (immunoportal.com)
- Reserpine works by depleting the levels of certain neurotransmitters, such as norepinephrine and serotonin, in the brain. (pricepropharmacy.su)
Potentiate1
- This combination may potentiate the action of other antihypertensive agents used concominantly. (medeasy.health)
Rescinnamine1
- The active ingredients in this drug are alkaloids and about 50 have been identified through various studies, although the primary psychoactive components appear to be reserpine, rescinnamine, and deserpidine 10 . (drugbank.com)
Depletes1
- An antihypertensive that depletes stores of catecholamines and 5-hydroxytryptamine in many organs, including the brain and adrenal medulla. (hempstreet.in)
Catecholamine1
- Concominant use with catecholamine depletor (eg, reserpine) may cause hypotension and/or marked bradycardia Calcium channel blockers, Amiodarone may have an additive effect when given with this combination. (medeasy.health)
Clonidine1
- These drugs include certain antidepressants and antihypertensive drugs such as clonidine or reserpine. (lifeafterjob.com)
HydrALAZINE2
- In such patients hydrALAZINE should be discontinued unless the benefit-to-risk determination requires continued antihypertensive therapy with this drug.Symptoms and signs usually regress when the drug is discontinued but residua have been detected many years later. (nih.gov)
- The Committee also noted that hydralazine, reserpine and methyldopa are all off-patent and therefore usually relatively inexpensive. (essentialmeds.org)
Antidepressants1
- These drugs include some antidepressants, antihypertensive drugs, and drugs that are used for psychiatric illnesses. (lifeafterjob.com)
Sedative1
- The plant has a long history of use in Ayurvedic medicine for its sedative and antihypertensive properties. (aarogyacbd.com)
Peripheral2
- The antihypertensive actions of Reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. (drugbank.com)
- Reserpine results in a rapid reduction in cardiac output, heart rate, and peripheral vascular resistance. (hempstreet.in)
Agents3
- Alkaloids from plants in this genus have been used as tranquilizers and antihypertensive agents. (dictionary.net)
- The mechanism of the antihypertensive effects of beta-blocking agents has not been fully elucidated. (nih.gov)
- It may be used alone or in combination with other antihypertensive agents, especially thiazide-type diuretics. (rxlist.com)
Agent1
- If an optimal response is not achieved, another antihypertensive agent may be added gradually beginning with 50 percent of the usual recommended starting dose to avoid an excessive fall in blood pressure. (medeasy.health)
Depression1
- Reserpine may cause mental depression . (wikidoc.org)
Drug4
- Methoserpidine is an antihypertensive drug related to reserpine. (wikipedia.org)
- Emergency Central , emergency.unboundmedicine.com/emergency/view/Davis-Drug-Guide/51659/all/reserpine. (unboundmedicine.com)
- Reserpine is almost completely metabolized in the body, and only about 1% is excreted as unchanged drug in the urine 15 . (drugbank.com)
- There is limited information regarding Clinical Trial Experience of Reserpine in the drug label. (wikidoc.org)
Compound1
- The plant contains a compound called reserpine, which has been shown to have potent antihypertensive effects. (pricepropharmacy.su)
Increases3
- reserpine increases toxicity of deutetrabenazine by pharmacodynamic synergism. (medscape.com)
- reserpine increases levels of berotralstat by P-glycoprotein (MDR1) efflux transporter. (medscape.com)
- Since reserpine increases gastrointestinal motility and secretion, it should be used cautiously in patients with a history of peptic ulcer , ulcerative colitis , or gallstones ( biliary colic may be precipitated). (wikidoc.org)
Withdrawal1
- Preoperative withdrawal of reserpine does not assure that circulatory instability will not occur. (wikidoc.org)
Therapy1
- Potential advantages for hydroflumethiazide and reserpine combination therapy may include improved compliance and synergistic reductions in blood pressure with an accompanied reduction in side effects. (syrianclinic.com)
Treatment1
- His manic symptoms improved markedly with the addition of reserpine to the treatment regimen. (sajp.org.za)
Adult2
- There is limited information regarding Off-Label Guideline-Supported Use of Reserpine in adult patients. (wikidoc.org)
- There is limited information regarding Off-Label Non-Guideline-Supported Use of Reserpine in adult patients. (wikidoc.org)
Levels3
- However, antihypertensive activity does not appear to be related to plasma levels. (nih.gov)
- Because of variable plasma levels attained with a given dose and lack of a consistent relationship of antihypertensive activity to dose, selection of proper dosage requires individual titration. (nih.gov)
- Mean maximum plasma levels of plasma concentrations after 0.5 mg of Reserpine, administered as two 0.25 mg tablets or as an aqueous solution, peaked after 2.5 hours. (drugbank.com)
High1
- Reserpine is used to treat high blood pressure. (drugbank.com)
Property1
- Reserpine (an indole alkoloid) is the antihypertensive principle having tranguillizing property also. (sdach.ac.in)
Medicine1
- Methyldopa was originally added to the EML in 1977 as an antihypertensive medicine. (essentialmeds.org)
Properties1
- Reserpine is a centrally acting antihypertensive with anti-adrenergic properties. (sajp.org.za)