• maturation
  • Although the new system codifies and standardizes the definitions of disease entities based upon histology, genetic abnormalities, and cell surface immunophenotype, its organization is based upon cell of origin (B cell vs. T cell) and maturation stage (precursor vs. mature) of the tumor, features that are of limited value to the clinician. (wordpress.com)
  • Infectious
  • A distinctive form of mononuclear inflammation usually evoked by infectious agents that resist eradication, but are capable of stimulating strong T cell mediated immunity. (brainscape.com)
  • granulomatous
  • By contrast, most cases of necrotizing scleritis show chronic granulomatous inflammation with epithelioid cells, multinucleated giant cells, lymphocytes, plasma cells, and less often neutrophils, along with inflammatory microangiopathy. (springer.com)
  • Wegener's granulomatosis a multisystem disease chiefly affecting males, characterized by necrotizing granulomatous vasculitis involving the upper and lower respiratory tracts, glomerulonephritis, and variable degrees of systemic, small vessel vasculitis, which is generally considered to represent an aberrant hypersensitivity reaction to an unknown antigen. (thefreedictionary.com)
  • tumor
  • This strategy involved the generation of DCs from monocytes or CD34 + precursors and the subsequent re-injection into the patient to generate effective T and B cell responses against the tumor. (frontiersin.org)
  • Additionally, several studies point to improved anti-tumor efficacy when the T cells are activated immediately prior to or directly after adoptive transfer. (frontiersin.org)
  • Inflammatory myofibroblastic tumor is composed of myofibroblast and inflammatory cell infiltration of the tissue. (hindawi.com)
  • In this report, we presented a 75-year-old male patient with inflammatory myofibroblastic tumor of the tongue presenting with pediculated large mass. (hindawi.com)
  • Initially, the incisional biopsy was done from mass, and the histopathological examination showed that the lesion was either a spindle cell carcinoma with an unusual appearance or an inflammatory myofibroblastic tumor. (hindawi.com)
  • stratum basale
  • basal cell an early keratinocyte, present in the stratum basale of the epidermis. (thefreedictionary.com)
  • This stratified squamous epithelium is maintained by cell division within the stratum basale, in which differentiating cells slowly displace outwards through the stratum spinosum to the stratum corneum, where cells are continually shed from the surface. (wikipedia.org)
  • Tissue
  • However, when scrapings are negative, analysis of conjunctival and scleral specimens by histopathology (stainings and cultures), tissue homogenization (PCR, culture, or cell culture lines), and indirect immunofluorescence (antimicrobe antibodies) techniques may be important for microbe isolation. (springer.com)
  • Tissue undergoes three kinds of studies: (1) light microscopy to discern the pattern of growth and the morphologic features of the malignant cells, (2) flow cytometry for assessment of immunophenotype, and (3) genetic studies (cytogenetics, DNA extraction). (wordpress.com)
  • Arias-Stella cells columnar cells in the endometrial epithelium which have a hyperchromatic enlarged nucleus and which appear to be associated with chorionic tissue in an intrauterine or extrauterine site. (thefreedictionary.com)
  • vimentin
  • Most spindle cells were strongly and diffusely stained positive with vimentin and alpha-smooth muscle actin, whereas negative with S-100 protein (Figures 3(a) - 3(e) ). (hindawi.com)
  • chronic
  • We studied the effect of highly active antiretroviral therapy (HAART) on the frequency of HIV-1-specific CD8+ T cells in patients treated during early (n = 31) or chronic (n = 23) infection. (jove.com)
  • tissues
  • Since DCs are localized, amongst other locations, in peripheral tissues such as the skin, new vaccines are aiming at targeting antigens to DCs in situ . (frontiersin.org)
  • immune
  • In susceptible persons, beryllium exposure can lead to a cell-mediated immune response. (wikipedia.org)
  • Besides triggering activating immune responses aiming at the clearance of pathogens, DCs are also capable to down-modulate unwanted auto-immune reactions by maintaining immune tolerance via the induction of regulatory T cells ( Maldonado and von Andrian, 2010 ). (frontiersin.org)
  • monoclonal
  • However, also this therapy is very costly and since effective TILs seem to be restricted to melanoma and genetically engineered T cells only possess monoclonal specificity, targeting DCs directly in vivo therefore provides an attractive alternative. (frontiersin.org)
  • Like other cancers, the malignant cells are monoclonal and often contain numerous genetic abnormalities. (wordpress.com)
  • regulatory T cel
  • This disclosure provides a method of identifying or separating activated regulatory T cells that have a demethylated Foxp3 TSDR region from a mixture of activated T cells. (patents.com)
  • lymphoma
  • Some genetic alterations are characteristic of particular histologic entities: t(8;14) in Burkitt's lymphoma, t(14;18) in follicular lymphoma, t(11;14) in mantle cell lymphoma, t(2;5) in anaplastic large cell lymphoma, translocations or mutations involving bcl-6 on 3q27 in diffuse large cell lymphoma, and others. (wordpress.com)
  • HTLV-I is associated with adult T cell leukemia/lymphoma. (wordpress.com)
  • Gastric Helicobacter pylori infection is associated with gastric MALT lymphoma and perhaps gastric large cell lymphoma. (wordpress.com)