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  • bind
  • Complement fragments, such as C3a, C4a and C5a, activate granular leukocytes (e.g., neutrophils), while other components of the system (C6, C7, C8, C9) either can form the membrane attack complex (MAC) or can bind the antibody, aiding phagocytosis by macrophages (C3b). (wikipedia.org)
  • More recently antibodies have been used to bind to molecules involved in T-cell regulation to remove inhibitory pathways that block T-cell responses. (wikipedia.org)
  • vaccine
  • Edible algae based vaccination is a developing vaccination strategy that usually combines a genetically engineering sub-unit vaccine and an immunologic adjuvant into Chlamydomonas reinhardtii micro algae. (wikipedia.org)
  • However, a significant production of IgG antibodies, which are the most common antibodies in circulation, was not found in mice that were only immunized solely via the edible algae vaccine. (wikipedia.org)
  • occurs
  • AIHA) occurs when antibodies directed against the person's own red blood cells (RBCs) cause them to burst (lyse), leading to an insufficient number of oxygen-carrying red blood cells in the circulation. (wikipedia.org)
  • tissues
  • Anatomical pathology (Commonwealth) or Anatomic pathology (U.S.) is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues. (wikipedia.org)
  • human
  • It was the first example of a human viral pathogen discovered using unbiased metagenomic next-generation sequencing with a technique called digital transcriptome subtraction. (wikipedia.org)
  • During this time, she learned about cutting-edge techniques in bacteriology and serology from Fredrick Parker Gay, and about immunologic tools in diagnosing human disease from Claus W. Jungeblu. (wikipedia.org)
  • Four major antibody types that have been developed are murine, chimeric, humanised and human. (wikipedia.org)
  • cells
  • Monoclonal antibody therapy may prove to be beneficial for cancer, autoimmune diseases, and neurological disorders that result in the degeneration of body cells, such as Alzheimer's Disease. (wikipedia.org)
  • Cytopathology - the examination of loose cells spread and stained on glass slides using cytology techniques. (wikipedia.org)
  • Flow immunophenotyping - the determination of the immunophenotype of cells using flow cytometry techniques. (wikipedia.org)
  • activity
  • Determine if intrathecal iodine I 131 monoclonal antibody 3F8 activity in patients with GD2-expressing central nervous system or leptomeningeal neoplasms is sufficiently promising (i.e., 6-month overall survival rate ≥ 25%) to warrant further study. (clinicaltrials.gov)
  • Classification of the antibodies is based on their activity at different temperatures and their etiology. (wikipedia.org)
  • Antibodies with high activity at physiological temperature (approximately 37 °C) are termed warm autoantibodies. (wikipedia.org)
  • types
  • Research and development is underway to create antibodies for diseases (such as rheumatoid arthritis, multiple sclerosis, Alzheimer's disease, Ebola and different types of cancers). (wikipedia.org)
  • surface
  • These methods of surface cooling were improved by the introduction of techniques in which the kidney's vascular system was flushed out with cold fluid prior to storage. (wikipedia.org)
  • Cancer
  • PURPOSE: This phase II trial is studying the side effects and how well iodine I 131 monoclonal antibody 3F8 works in treating patients with central nervous system cancer or leptomeningeal cancer. (clinicaltrials.gov)
  • With improvements in breast imaging and image-guided interventions, there is interest in ablative techniques for breast cancer. (wikipedia.org)
  • study
  • 2) Experiments using current techniques to study different aspects of the cell and its function. (utm.edu)
  • similar
  • Stueber showed that kidneys would survive in situ clamping of the renal pedicle for 6 hours if the kidneys were cooled to 0-5 °C by being placed in a cooling jacket, and Schloerb showed that a similar technique with cooling of heparinised dog kidneys to 2-4 °C gave protection for 8 hours but not 12 hours. (wikipedia.org)
  • This technique is critical to distinguishing between disorders with similar morphology, as well as characterizing the molecular properties of certain cancers. (wikipedia.org)
  • blood
  • Kiser used this technique to achieve successful 7 hours in vitro storage of a dog kidney, when the kidney had been flushed at 5 °C with a mixture of dextran and diluted blood prior to storage. (wikipedia.org)
  • antigens
  • Each class of antibody binds to corresponding molecules (antigens) on the cell surfaces of certain foreign organisms or substances, attempting to protect the body against reactions or illness. (encyclopedia.com)
  • specific
  • Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the. (naver.com)
  • In these disorders, specific diseasefighting antibodies (immunoglobulins such as IgG, IgA, and IgM) are either missing or are present in reduced levels. (encyclopedia.com)
  • Immunoglobulin deficiencies refer to missing or reduced levels of immunoglobulin (IgG, IgA, IgM) associated with an inability to make adequate specific antibody. (encyclopedia.com)
  • These antibodies are specific proteins (immunoglobulins) produced by the immune system to respond to bacteria, viruses, fungi, parasites, or toxins that invade the body. (encyclopedia.com)
  • However, recent investigation provides an alternative structure of 19S base via an integrative approach combining data from cryoelectron microscopy, X-ray crystallography, residue-specific chemical cross-linking, and several proteomics techniques. (wikipedia.org)
  • human
  • It was the first example of a human viral pathogen discovered using unbiased metagenomic next-generation sequencing with a technique called digital transcriptome subtraction. (wikipedia.org)
  • Sadun's major research thrust was on the human immunologic reaction to parasitic diseases, or more precisely, host-parasite immunological interactions. (wikipedia.org)
  • The conference annals edited by E.H. Beutner, R. Nisengard and B. Albin (2) focused on the reproducible detections antinuclear antibodies (ANA) with fluorescein labeled antibodies to human IgG. (wikipedia.org)
  • Memory
  • Mature B cells are capable of making antibodies and developing memory, a feature in which the B cell will rapidly recognize and respond to an infectious agent the next time it is encountered. (encyclopedia.com)
  • expression
  • Further studies have been conducted in C. reinhardtii and have depended heavily upon antigen expression yields, antibody titers elicited from the antigen and the adjuvent(delivery system) that the vaccine was administered with. (wikipedia.org)
  • blood
  • Kiser used this technique to achieve successful 7 hours in vitro storage of a dog kidney, when the kidney had been flushed at 5 °C with a mixture of dextran and diluted blood prior to storage. (wikipedia.org)
  • allows
  • Breastfeeding triggers biochemical reactions which allows for the enzymes, hormones, growth factors and immunologic substances to effectively defend against infectious diseases for the infant. (wikipedia.org)