• gp120
  • This antibody attached to a "conserved" portion of gp120 that outlasts many of its mutations, affecting 17/24 tested strains at low doses. (wikipedia.org)
  • He repeatedly donated blood over the course of a year, which researches used to create a timeline of changes in his virus' gp120, his antibody response and the ultimate emergence of a bNAb. (wikipedia.org)
  • A screen of massive gp120 libraries led to one that strongly bound both an original antibody and the mature bNAb that evolved from it. (wikipedia.org)
  • Giving patients a modified gp120 that contains little more than the epitope that both antibodies target could act to "prime" the immune system, followed by a booster that contains trimer spikes in the most natural configuration possible. (wikipedia.org)
  • strains
  • They individually probed 30,000 of one woman's antibody-producing B cells and isolated two that were able to stop more than 70% of 162 divergent HIV strains from establishing an infection. (wikipedia.org)