• nuclear
  • 2 Abeles and Abeles Clinical Utility of Positive Antinuclear Antibody 343 cubating patient serum on a cellular antigen substrate (typically HEp-2 cells, which are clonal cancer cells useful in this assay for their large nuclei), and then, after a washing step, detecting patient antibodies bound to nuclear antigens through the addition of fluorescence-tagged anti-immunoglobulin G antibodies. (docplayer.net)