OrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesHealth Care
Heterocyclic Compounds, Bridged-RingHIV InfectionsAnti-Bacterial AgentsHIV SeropositivityMicrobial Sensitivity TestsBacteriaGram-Positive BacteriaGram-Negative BacteriaAnti-Infective AgentsHIV SeroprevalenceStaphylococcus aureusHIV SeronegativityAntimicrobial Cationic PeptidesPlant ExtractsMolecular StructureEscherichia coliSilver
AntimicrobialInhibitorsProteaseDerivativesWater-solubleAntimalarial agentCompoundsPotentVitroTherapeutic agentsInfectionAntioxidantAIDSActivitiesDrugsBacterialInfectious agentsMedicationsPropertiesTreatmentApoptosisExtractVirusesPatientsActionMedicationEffectiveApplicationsResearchPotentialStartCurrentCancerStudyStudiesShown
Antimicrobial6
  • Antimicrobial Agents and Chemotherapy, 2018. (nih.gov)
  • Carboxyfullerene directly inhibits in vitro growth of Streptococcus pyogenes and enhances bactericidal activity of neutrophils in mice in vivo [ 5874 ], suggesting that the fullerene derivative "can be considered an antimicrobial agent for group A streptococcus infection. (nanomedicine.com)
  • Gromwell root is sweet in taste and has been shown to be antimicrobial, antiviral, antifungal, and anti-inflammatory. (articlefeed.org)
  • 5 It also contains potent antimicrobial action, meaning it is antibacterial, antifungal, and antiviral by nature. (articlefeed.org)
  • Despite the wide success of antimicrobial agents against waterborne pathogens, waterborne disease continues to pose a threat to both mankind and animals. (uwc.ac.za)
  • They represent a very interesting class of compounds because of their wide applications as antimicrobial, anti-inflammatory, anti-degenerative and anti-HIV activities. (org.in)
Inhibitors3
  • By 1998, computational models for optimizing the binding of fullerene inhibitors of the HIV-1 protease led to the synthesis and testing of two C 60 -derived ligands for the HIV protease active site that displayed ~50-fold increase in affinity compared to previously tested fullerene compounds [ 735 ]. (nanomedicine.com)
  • Identification and validation of novel notch signaling pathway inhibitors as potential anticancer agents of natural origin. (edu.in)
  • Receptors and drug action:drug-receptor interactions, ion channels, G-protein-coupled receptors, nuclear receptors, protein kinases, intracellular receptors for gene transcription regulation, antibacterial inhibitors of protein synthesis, enzymes as drug targets. (unizg.hr)
Protease5
  • Prezcobix (darunavir and cobicistat) is a combination of a human immunodeficiency virus ( HIV -1) protease inhibitor and a CYP3A inhibitor and is indicated for the treatment of HIV-1 infection in adult patients. (rxlist.com)
  • Darunavir is an inhibitor of the human immunodeficiency virus ( HIV -1) protease . (rxlist.com)
  • In 1993, MSAD-C 60 was found effective against HIV-1 and HIV-2 with 50% effective concentration (EC50) averaging 6 x 10 -6 M in acutely or chronically infected human lymphocytes, and with selective activity against HIV-1 protease [ 732 ]. (nanomedicine.com)
  • A C 60 molecule covalently linked to peptide T, like peptide T, displays potent human monocyte chemotaxis while weakly inhibiting HIV-1 protease [ 693 ]. (nanomedicine.com)
  • Several reports have demonstrated dihydropyridine derivatives as a potentiator of cystic fibrosis transmembrane conductance regulator protein, potent antimalarial agent and HIV-1 protease inhibitor. (cysticfibrosistreatmentreport.com)
Derivatives3
  • In particular, the discovery of the new use of artemisinin derivatives as excellent anti-cancer drugs is also reviewed. (anti-agingfirewalls.com)
  • Other studies [ 5877 ] have also found antibacterial activity of fullerene derivatives, and even of carbon nanotubes [U. Sagman, personal communication, December 2002]. (nanomedicine.com)
  • In vitro cytotoxicity against the HeLa S3 cell line has been evaluated by studying the inhibited growth rate [ 922 ], and some C 60 derivatives have shown promise as anti-cancer agents [ 1090 - 1092 ]. (nanomedicine.com)
Water-soluble1
  • Flormidal is a short-acting, water soluble benzodiazepine used as a sedative and anesthetic agent. (generic-meds-store.com)
Antimalarial agent1
Compounds6
  • Large numbers of heterocyclic compounds are being used as therapeutic agents. (ijpsonline.com)
  • This review highlights the important role of Erythrina species as sources of lead compounds or new class of phytotherapeutic agents for fighting against major public health (MDR infections, cancer, diabetes, obesity) in Sub-Saharan Africa. (scialert.net)
  • All the compounds were screened for their tuberculostatic, antibacterial, and anticancer activities. (springer.com)
  • Preliminary results indicated that target compounds exhibited weak tuberculostatic and antibacterial activities. (springer.com)
  • The synthesized compounds were evaluated for their biological activity in vitro: tuberculostatic, antibacterial, cytotoxic, and anticancer. (springer.com)
  • A large body of epidemiological studies has proven the bioactivities of phenolics in both standard compounds and natural extracts: namely, anticancer, anti-inflammatory, and antibacterial activities as well as reducing diabetes, cardiovascular disease, and neurodegenerative disease. (mdpi.com)
Potent2
  • However, recent data shows that leptomycin causes G1 cell cycle arrest in mammalian cells and is a potent anti-tumor agent against murine experimental tumors in combination therapy. (wikipedia.org)
  • In addition to antifungal and antibacterial activities, leptomycin B blocks the cell cycle and is a potent anti-tumor agent. (wikipedia.org)
Vitro1
  • This article summarizes recent advances in in vitro and in vivo research on the anti-cancer effects and related mechanisms of some promising natural products. (anti-agingfirewalls.com)
Therapeutic agents1
  • The study recommended that Shikonin, and more broadly, it is a worthy natural component to be included in the development of novel anti-HIV therapeutic agents. (articlefeed.org)
Infection1
  • The development of bacterial resistance to available antibiotics and increasing incidence of multi resistant bacterial infections in hospitals and in the community has necessitated the search for new antibacterial agents to treat the bacterial infection. (org.in)
Antioxidant1
  • Some species also exhibited antioxidant, anti-inflammatory activities and enzymes inhibitory properties. (scialert.net)
AIDS3
  • Women who have HIV/ AIDS should not breastfeed due to the potential for HIV transmission and the potential for serious adverse reactions in nursing infants. (rxlist.com)
  • This situation is serious because microbial infections are the most frequent opportunistic diseases occurring during HIV/aids which affected many people in Africa. (scialert.net)
  • Acyclovir), HIV-AIDS (e.g. (eurekaselect.com)
Activities1
  • Moreover, it has been exploited for the treatment of a variety of cardiovascular diseases due to its potential antihypertensive, anti-angina, vasodilator, and cardiac depressant activities. (cysticfibrosistreatmentreport.com)
Drugs3
  • the company's anti-HIV drugs apparently have about one-tenth the toxicity of current HIV cocktails, and human trials start in 2003 [ 259 ]. (nanomedicine.com)
  • To eliminate cancerous cells effectively, the anti-cancer drugs must be targeted to the affected cells. (uwc.ac.za)
  • BPaL was approved in accordance with the Limited Population Pathway for Antibacterial and Antifungal Drugs (LPAD) for development of drugs targeting infections that lack effective therapies. (cdc.gov)
Bacterial1
  • E. coli -induced increases in blood-brain barrier permeability and inflammatory neutrophilic infiltration were also inhibited [ 5876 ], suggesting that the C 60 compound could be a useful therapeutic agent in some cases of bacterial meningitis [ 738 ]. (nanomedicine.com)
Infectious agents1
  • Viruses are infectious agents for which modern medicine has limited treatment. (iherb.com)
Medications2
  • Patients who have had TEN must be counseled regarding the likely causative medication or agent, and they must be advised to avoid these medications and those of the same or similar classes in the future. (medscape.com)
  • is actively being studied in combination with other anti-TB medications not included in the BPaL regimen. (cdc.gov)
Properties6
  • The area is that of traditional Chinese herbal substances that have also been extensively researched only in China, but using the latest tools and intellectual frameworks of Western science and shown to have anti-cancer properties. (anti-agingfirewalls.com)
  • On this blog entry, emphasis will on an additional substances with anti-cancer properties, ones derived from gamboge resin. (anti-agingfirewalls.com)
  • One study found that the antiviral and anti-inflammatory properties of Shikonin, a phytochemical extract from Gromwell root, inhibited chemokine receptor function, and suppressed HIV Type 1. (articlefeed.org)
  • One theory is that the antibacterial properties of silver were known, and this was done to make water safer to drink. (iherb.com)
  • A 2016 study showed that silver had anti-fungal properties when tested at various concentrations. (iherb.com)
  • Phenolics also display anti-analgesic, anti-allergic, and anti-Alzheimer's properties. (mdpi.com)
Treatment1
  • 9. Severe infections (requiring hospitalization, parenteral treatment with antibacterial, antimycotic, or antiprotozoal agents) within 30 days before signing the informed consent form and during the screening period. (who.int)
Apoptosis1
  • We reported novel notch signaling inhibitor(s), and apoptosis inducer agents in cancer and cancer stem-like cells. (edu.in)
Extract1
  • Synthesis of silver doped titanium dioxide nanocomposites using tea extract from Aspalathus linearis and evaluation of their antibacterial effects. (uwc.ac.za)
Viruses1
  • By the late 1990s [ 736 ], photodynamic reactions induced by singlet oxygen-generating agents were known to inactivate enveloped viruses [ 682 ]. (nanomedicine.com)
Patients2
  • 7. A CD19+ cell proportion of = 1 % of the total lymphocyte count in patients exposed to other anti-B-cell therapies more than 6 months before signing the informed consent form. (who.int)
  • 2. Intrathecal oligoclonal or monoclonal IgG production (only in patients who are anti-AQP4 seronegative). (who.int)
Action1
  • Subsequent work [ 5875 ] by this research group found that the antibacterial action of carboxyfullerene on Gram-positive bacteria is achieved by insertion into the cell wall and destruction of membrane integrity. (nanomedicine.com)
Medication1
  • He was prescribed steroids and anti-inflammatory medication, and symptoms temporarily improved. (cdc.gov)
Effective1
  • Manuka honey appears to be an effective antibacterial wound healing agent against MRSA-colonized leg ulcers. (greenmedinfo.com)
Applications1
  • In this article, an overview is provided on the preparation and applications of various antibacterial hydrogels. (eurekaselect.com)
Research1
  • Currently, hydrogels with an antibacterial function are a research hotspot in biomedical field. (eurekaselect.com)
Potential1
  • Many Erythrina species showed real potential for fighting against pathogenic agents incriminated in alarming public health problems in sub-Saharan Africa. (scialert.net)
Start1
  • A good place to start is with the July 2011 e-publication Anti-cancer natural products isolated from chinese medicinal herbs , as to be expected written by a team of Chinese researchers. (anti-agingfirewalls.com)
Current1
  • The current study proposes silver nanoparticles (AgNPs) as an antibacterial agent. (uwc.ac.za)
Cancer3
  • The Part 1 post in this series is concerned principally with anti-cancer interventions that address the mTOR pathway, a growth pathway also of great interest from the viewpoint of longevity. (anti-agingfirewalls.com)
  • The Part 2 post in this series is concerned with mainline anti-cancer drug interventions that simultaneously address multiple growth pathways, ones that are entering clinical practice. (anti-agingfirewalls.com)
  • 3) Tumor/Anti-Cancer Therapy . (nanomedicine.com)
Study1
  • A 2005 study in Journal of Nanobiotechnology showed silver could stop the HIV virus from binding to host cells. (iherb.com)
Studies1
  • While these studies provide some hope for future treatments, colloidal silver should not be used as a method to prevent HIV or herpes infections. (iherb.com)
Shown1
  • Fullerenes have shown activity against HIV [ 693 , 732 - 735 , 1096 - 1098 ]. (nanomedicine.com)