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  • toothpaste
  • Triclosan is commonly found in antibacterial personal-care products such as hand soaps as well as deodorants, mouthwashes, toothpaste, bedding, clothes, carpets, toys and trash bags. (quantumday.com)
  • A study by Colgate-Palmolive found a significant reduction in gingivitis, bleeding, and plaque with the use of triclosan-containing toothpaste, but an independent review of the Cochrane group suggests that while the reduction in gingivitis, bleeding, and plaque may be statistically significant, it may not be beneficial enough to yield clinical significance. (wikipedia.org)
  • Chlorhexidine is used in disinfectants (disinfection of the skin and hands), cosmetics (additive to creams, toothpaste, deodorants, and antiperspirants), and pharmaceutical products (preservative in eye drops, active substance in wound dressings and antiseptic mouthwashes). (wikipedia.org)
  • organisms
  • The U.S. Environmental Protection Agency in 1998 estimated that more than 1 million pounds of triclosan are produced annually in the United States, and that the chemical is detectable in waterways and aquatic organisms ranging from algae to fish to dolphins, as well as in human urine, blood and breast milk. (quantumday.com)
  • efficacy
  • Manufacturers have not demonstrated the safety or efficacy of 19 antibacterial agents common in hand and body soaps, according to the US Food and Drug Administration. (the-scientist.com)
  • In 2011, a large clinical trial designed to evaluate the efficacy of hand sanitizers based on different active ingredients in preventing virus transmission amongst schoolchildren was re-designed to exclude sanitizers based on benzalkonium chloride due to safety concerns. (wikipedia.org)
  • Under the test conditions of the European Standard EN 1499, no significant difference in the efficacy was found between a 4% solution of chlorhexidine digluconate and soap. (wikipedia.org)
  • molecular
  • Triclosan is found in virtually everyone's home and is pervasive in the environment," said Isaac Pessah, professor and chair of the Department of Molecular Biosciences in the UC Davis School of Veterinary Medicine and principal investigator of the study. (quantumday.com)
  • Specifically, the team evaluated the effects of triclosan on molecular channels in muscle cells that control the flow of calcium ions, creating muscle contractions. (quantumday.com)
  • Triclosan has been employed as a selective agent in molecular cloning. (wikipedia.org)
  • water
  • Those exposed to triclosan in the water for seven days had significantly reduced swimming activity compared to controls during both normal swimming and swim tests designed to imitate fish being threatened by a predator. (quantumday.com)
  • NRDC's lawsuit comes on the heels of Beyond Pesticides, Food and Water Watch, and other NGOs having submitted a petition (pdf) to FDA calling for a ban on nonmedical uses of triclosan, citing the possibility of bacterial resistance to antibacterial substances and antibiotics, along with other concerns. (greenbiz.com)
  • If water and soap is not available, hands can be cleaned with ash instead. (wikipedia.org)
  • Interventions that promote hand washing can reduce diarrhoea episodes by about a third, and this is comparable to providing clean water in low income areas. (wikipedia.org)
  • Hand washing is usually integrated together with other sanitation interventions as part of water, sanitation and hygiene (WASH) programmes. (wikipedia.org)
  • Triclosan is soluble in ethanol, methanol, diethyl ether, and strongly basic solutions such as a 1M sodium hydroxide solution, but only slightly soluble in water. (wikipedia.org)
  • The United States FDA has found that triclosan provides no health benefits over soap and water. (wikipedia.org)
  • exposure
  • Finally, the investigators looked at the effects of triclosan exposure on fathead minnows, a small fish commonly used as a model organism for studying the potential impacts of aquatic pollutants. (quantumday.com)
  • survival
  • There are arguments for creating or maintaining conditions that are not conducive to bacterial survival and multiplication, rather than attempting to kill them with chemicals. (wikipedia.org)
  • resistant
  • showering with 2% triclosan has become a recommended regimen in surgical units for the decolonization of patients whose skin carries methicillin-resistant Staphylococcus aureus (MRSA). (wikipedia.org)
  • skin
  • A possible small detrimental effect of hand washing is that frequent hand washing can lead to skin damage due to drying of the skin. (wikipedia.org)
  • It is usually a highly-foaming mixture of surfactants with low skin irritation, and is primarily used for hand washing of glasses, plates, cutlery, and cooking utensils in a sink or bowl. (wikipedia.org)
  • Chlorhexidine gluconate is used as a skin cleanser for surgical scrubs, a cleanser for skin wounds, for preoperative skin preparation and germicidal hand rinses. (wikipedia.org)
  • The legs should be dried thoroughly after washing with antibacterial shampoo using paper towels, There are many products available to help protect the skin from the constant wet by forming a barrier between the mud and the leg. (wikipedia.org)
  • evaluate
  • The investigators performed several experiments to evaluate the effects of triclosan on muscle activity, using doses similar to those that people and animals may be exposed to during everyday life. (quantumday.com)
  • chemicals
  • According to NRDC, FDA first proposed a rule that would have removed these chemicals from soaps in 1978, but has not finalized it. (greenbiz.com)
  • found
  • The team also found that triclosan impairs heart and skeletal muscle contractility in living animals. (quantumday.com)
  • Elsewhere, triclosan has been found to create problems at wastewater treatment plants, whereby it can "sabotage some sludge-processing microbes and promote drug resistance in others. (wikipedia.org)
  • products
  • Triclosan, an antibacterial chemical widely used in hand soaps and other personal-care products, hinders muscle contractions at a cellular level, slows swimming in fish and reduces muscular strength in mice, according to researchers at the University of California, Davis, and the University of Colorado. (quantumday.com)
  • Triclosan's had a good run for many years, driving a strong market for anti-bacterial hand soaps and other products, but at some point the reputational and marketing liabilities of triclosan may outweigh financial benefits. (greenbiz.com)
  • If your company's not examining a "no triclosan" scenario for its consumer products, especially soaps, you may be ill-prepared to be shut out of the market. (greenbiz.com)
  • Conversely, you ought to be considering enlarged market share opportunities for triclosan-free products. (greenbiz.com)
  • EPA's March 2010 " Triclosan Facts " notes the chemical is used in adhesives, fabrics, vinyl, plastics, textiles, carpeting, and a wide variety of other consumer products. (greenbiz.com)
  • environmental
  • EPA states it will launch another comprehensive review of triclosan beginning in 2013, reexamining both human health and environmental hazards. (greenbiz.com)
  • With respect to environmental impacts, the agency seems mainly concerned about discharges at industrial sites where triclosan is added to plastics and textiles. (greenbiz.com)
  • Additional research seeks to understand its potential for causing antibacterial resistance and its effects on organismal and environmental health. (wikipedia.org)
  • effects
  • The effects of triclosan on cardiac function were really dramatic," said Nipavan Chiamvimonvat, professor of cardiovascular medicine at UC Davis and a study co-author. (quantumday.com)
  • stop
  • In April 2010, Representative Edward Markey, Chair of the Energy and Environment Subcommittee of the House Energy and Commerce Committee wrote to 13 major manufacturers urging them to voluntarily stop using triclosan. (greenbiz.com)
  • acts
  • Although triclosan is not regulated as a drug, this compound acts like a potent cardiac depressant in our models. (quantumday.com)
  • By mimicking the natural substrate of the enoyl-acyl-carrier protein reductase (ENR) enzyme, triclosan acts as a site-directed inhibitor and disrupts lipid, phospholipid, lipopolysaccharide and lipoprotein synthesis. (wikipedia.org)
  • infections
  • According to UNICEF, turning hand washing with soap before eating and after using the toilet into an ingrained habit can save more lives than any single vaccine or medical intervention, cutting deaths from diarrhea by almost half and deaths from acute respiratory infections by one-quarter. (wikipedia.org)
  • currently
  • Triclosan safety is currently under review by the U.S. Food and Drug Administration (FDA) and Health Canada. (quantumday.com)
  • In its April 2010 fact sheet for consumers, FDA stated, "Triclosan is not currently known to be hazardous to humans. (greenbiz.com)
  • hygiene
  • Medical hand hygiene refers to hygiene practices related to medical procedures. (wikipedia.org)
  • In environments with high lipids or protein waste (such as food processing), the use of alcohol hand rubs alone may not be sufficient to ensure proper hand hygiene. (wikipedia.org)
  • presence
  • But in the presence of triclosan, the normal communication between two proteins that function as calcium channels was impaired, causing skeletal and cardiac muscle failure. (quantumday.com)
  • Food
  • There are five critical times during the day where washing hands with soap is important to reduce fecal-oral transmission of disease: after defecation, after cleaning a child's bottom, before feeding a child, before eating and before preparing food or handling raw meat, fish, or poultry. (wikipedia.org)
  • liquid
  • Dishwashing liquid (BrE: washing-up liquid), known as dishwashing soap, dish detergent and dish soap, is a detergent used to assist in dishwashing. (wikipedia.org)
  • form
  • Then, 1-vinylpyrrolidin-2-one can be reacted with 5-chloro-2-(2,4-dichlorophenoxy)phenyl acrylate in n-heptane to form triclosan. (wikipedia.org)
  • Alternatively, some form of covering for the leg may be used such as Anti mud fever boots. (wikipedia.org)
  • cosmetics
  • However, over the last 20 years, they have been used increasingly in cosmetics and personal care products, in food processing, on inanimate objects, in clothing, and for the treatment of bacterial disease in animals, fish, and plants. (beyondpesticides.org)
  • The US Food and Drug Administration first registered triclosan in 1969 , and the chemical has been added to countless soaps, cosmetics and cleaning products since then. (wordpress.com)
  • germs
  • Some people think that just running water over our hands will rinse off the germs. (hubpages.com)
  • They claim it is animal lard/dung and does nothing to remove dirt but it is the action of rubbing the hands together that gets dirt and germs off? (hubpages.com)
  • While they do kill germs on your hands they don't work as effectively as they claim. (hubpages.com)
  • In your mind you should be thinking Soap, Alcohol, pH, Acids, and other Bactericidal elements to use that actually do not promote resistance to attacking germs. (mythichealth.com)
  • disease
  • While that was in test tubes, not on actual humans, that's much longer than the 20 seconds the US Centres for Disease Control and Prevention recommends you take to wash your hands. (wordpress.com)
  • Hand washing before administering medicine or medical care can prevent or minimize the spread of disease. (wikipedia.org)
  • natural
  • By mimicking the natural substrate of the enoyl-acyl-carrier protein reductase (ENR) enzyme, triclosan acts as a site-directed inhibitor and disrupts lipid, phospholipid, lipopolysaccharide and lipoprotein synthesis. (wikipedia.org)
  • mouth
  • People can become infected with respiratory diseases such as influenza or the common cold, for example, if they do not wash their hands before touching their eyes, nose, or mouth. (wikipedia.org)