• ocular
  • The purpose of this study is to evaluate patient perceptions of olopatadine 0.2% dosed once daily in patients previously treated with twice-daily, topical, ocular, anti-allergy medications. (clinicaltrials.gov)
  • The ocular allergic response is a cascade of events that is coordinated by mast cells. (wikipedia.org)
  • 1989
  • In order to secure funding for a start-up company based on family funds, the Changs sought collaboration with Genentech in 1989, sending data and samples of early anti-IgE antibody, but talks with Genentech were unsuccessful. (wikipedia.org)
  • treatment
  • Chang is a cofounder of Tanox, a biopharmaceutical company specialized in anti-IgE therapies for the treatment of allergic diseases. (wikipedia.org)
  • Originating from Chang's research, antibodies that target the IgE-mediated allergic pathway have proven effective in the treatment of various allergic diseases. (wikipedia.org)
  • inflammatory
  • Amlexanox (trade name Aphthasol) is an anti-inflammatory antiallergic immunomodulator used to treat recurrent aphthous ulcers (canker sores), and (in Japan) several inflammatory conditions. (wikipedia.org)
  • The drug is an anti-inflammatory, antiallergic immunomodulator. (wikipedia.org)
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) alleviate pain by counteracting the cyclooxygenase (COX) enzyme. (wikipedia.org)
  • On the other hand, there are analgesics that are commonly associated with anti-inflammatory drugs but that have no anti-inflammatory effects. (wikipedia.org)
  • Antileukotrines are anti-inflammatory agents which function as leukotriene-related enzyme inhibitors (arachidonate 5-lipoxygenase) or leukotriene receptor antagonists (cysteinyl leukotriene receptors) and consequently oppose the function of these inflammatory mediators. (wikipedia.org)
  • ImSAIDs are a class of peptides being developed by IMULAN BioTherapeutics, LLC, which were discovered to have diverse biological properties, including anti-inflammatory properties. (wikipedia.org)
  • The ImSAIDs represent a new category of anti-inflammatory and are unrelated to steroid hormones or nonsteroidal anti-inflammatories. (wikipedia.org)
  • One SGP-T derivative is a three-amino acid sequence shown to be a potent anti-inflammatory molecule with systemic effects. (wikipedia.org)
  • receptor
  • Meclizine, a piperazine-derivative H 1 -receptor antagonist similar to buclizine, cyclizine, and hydroxyzine, is used as an antivertigo/antiemetic agent. (pharmacycode.com)
  • nausea
  • The most common adverse effects noted for second-generation agents include drowsiness, fatigue, headache, nausea and dry mouth. (wikipedia.org)
  • Phase
  • Chang not only proposed the theory behind anti-IgE therapeutics, but also actively participated in the phase I and II clinical trials of Talizumab from 1990 to 1996. (wikipedia.org)
  • allergy
  • Proxicromil was developed in the late 1970s as an oral analogue and a successor of anti-allergy drug Intal, whose patent protection period was to expire in 1982. (wikipedia.org)
  • drug
  • Pirquinozol (SQ-13,847) is a drug which was investigated as an antiallergen and antiasthmatic agent in the early 1980s but was never marketed. (wikipedia.org)
  • Name
  • Urushiol-induced contact dermatitis (also called Toxicodendron dermatitis and Rhus dermatitis) is the medical name given to allergic rashes produced by the oil urushiol, which is contained in various plants, most notably those of the Toxicodendron genus: the Chinese lacquer tree, poison ivy, poison oak, and poison sumac. (wikipedia.org)