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Descemet MembraneDescemet Stripping Endothelial KeratoplastyFuchs' Endothelial DystrophyEye BanksCorneal Endothelial Cell LossCorneal EdemaEndothelium, CornealKeratoplasty, PenetratingCorneal DiseasesCorneal StromaPseudophakiaMembranesMembrane LipidsCell MembraneIntracellular MembranesVisual AcuityCorneal TransplantationMembrane PotentialsMembranes, ArtificialEncyclopedias as TopicConjunctivaConnective Tissue CellsFibrillar CollagensCorneaAcinar Cells
KeratoplastyDMEKLamellarDetachmentEndotheliumStromaHost Descemet membraneOptical coherenceKeratoconusGraftEpithelialFoldsCalled Descemet's membraneBowman'sSpontaneousBowmanEndothelial cellsRupturePosterior surfaceSurgeryMembranaMesenchymalThird of the corneaGlaucomaDonorArtificialIrisDouble anterior chamberCiliaryOcularPeripheralDeepAqueousPhotographing the anterior chamberTearChamber angleSurgicalInjection
Keratoplasty22
  • Obata H, Tsuru T. Corneal wound healing from the perspective of keratoplasty specimens with special reference to the function of the Bowman layer and Descemet membrane. (medscape.com)
  • Prevention and Management of Graft Detachment in Descemet Membrane Endothelial Keratoplasty. (medscape.com)
  • Melles GR, Ong TS, Ververs B, van der Wees J. Preliminary clinical results of Descemet membrane endothelial keratoplasty. (medscape.com)
  • Conventional endothelial keratoplasty (EK) entails stripping off the Descemet's membrane (DM) and transplantation of the posterior lamellar graft. (bmj.com)
  • Purpose: The aim of this study was to evaluate how Scheimpflug-derived parameters of eyes with Fuchs endothelial corneal dystrophy (FECD) are influenced by Descemet membrane endothelial keratoplasty (DMEK) depending on FECD severity and the presence of subclinical edema. (hu.nl)
  • In deep anterior lamellar keratoplasty (DALK), AS-OCT gives valuable information on preoperative decision process. (intechopen.com)
  • Before deciding for a Descemet membrane endothelial keratoplasty (DMEK), preoperative stromal scars can be identified with an AS-OCT and might affect the decision of the surgical procedure (DMEK or penetrating keratoplasty). (intechopen.com)
  • I considered performing Descemet-stripping endothelial keratoplasty at this juncture, but I decided to irrigate and aspirate as much blood as possible and proceed as planned. (crstoday.com)
  • Would you consider combining intervention with Descemet membrane endothelial keratoplasty (DMEK) or Descemet-stripping endothelial keratoplasty? (crstoday.com)
  • Endothelial rejection is also of concern following posterior lamellar transplantation (Descemet's Stripping Automated Endothelial Keratoplasty, DSAEK, and Descemet's Membrane Endothelial Keratoplasty, DMEK), although it does not occur following DALK where rejection may occur in the epithelium or stroma layers. (college-optometrists.org)
  • Deep anterior lamellar keratoplasty has been proposed as an excellent alternative to penetrating keratoplasty for corneal diseases that do not affect the endothelium. (eyerounds.org)
  • These are ultra-violet corneal crosslinking and intracorneal ring segments for mild to moderate keratoconus, and penetrating keratoplasty or deep anterior lamellar keratoplasty for the more advanced cases of keratoconus. (biomedcentral.com)
  • By being a sutureless procedure and using an acellular graft, it potentially avoids commonly known suture and graft-related complications of penetrating or deep anterior lamellar keratoplasty. (biomedcentral.com)
  • In his course on transitioning from Descemet's stripping endothelial keratoplasty to Descemet's membrane endothelial keratoplasty, Dr. McKee uses this case as an example of the sinister phenomenon known as negative transfer, where a skill or maneuver that used to be useful in one task is now actually detrimental in a new one. (reviewofophthalmology.com)
  • Forty-three (69.35%) underwent penetrating keratoplasty and 19 (30.65%) deep anterior lamellar keratoplasty (using the big-bubble technique). (touchophthalmology.com)
  • We realised a deep anterior keratoplasty with pathologies involving the corneal stroma and sparing the Descemet membrane. (touchophthalmology.com)
  • The technique for a lamellar keratoplasty involves removal of the anterior portion of the donor corneal stroma and epithelium. (vetbloom.com)
  • Therefore deep anterior lamellar keratoplasty involves dissection to the level of, but does not include) Descemet's membrane. (vetbloom.com)
  • PPMD patients with bilateral, corneal opacities that can affect vision, descemet's membrane endothelial keratoplasty or penetrating keratoplasty are the treatments of choice to improve vision and to avoid amblyopia. (mdwiki.org)
  • Region of Interest Densitometry Analysis of Descemet Membrane Endothelial Keratoplasty Dehiscence on Anterior Segment Optical Coherence Tomography. (ucsd.edu)
  • in a corneal transplant technique known as deep anterior lamellar keratoplasty (DALK) the donated corneal tissue replaces the corneal stroma and epithelium only. (msdmanuals.com)
  • In corneal endothelium transplantation, there are 2 techniques: Descemet stripping endothelial keratoplasty (DSEK) and the newest technique, Descemet membrane endothelial keratoplasty (DMEK). (msdmanuals.com)
DMEK1
Lamellar1
  • Histologically, it is characterized by an absent or fragmented Bowman layer, thinned stroma with normal lamellar organization, and a thin Descemet membrane. (aao.org)
Detachment7
  • Viscoelastic or refluxed blood can collect there, causing a Descemet's membrane detachment. (aao.org)
  • In a three-year follow-up of 157 canaloplasty patients, Descemet's membrane detachment was noted in 3.2 percent. (aao.org)
  • A retrospective study on the incidence of post-cataract surgery Descemet's membrane detachment and outcome of air descemetopexy. (jamanetwork.com)
  • Descemet's membrane detachment with schisis induced by phacoemulsification. (jamanetwork.com)
  • Complex Descemet's membrane tears and detachment during phacoemulsification. (jamanetwork.com)
  • 10.1055/b-0035-121726 11 Descemet Membrane Detachment: Classification and ManagementSoosan Jacob and Amar Agarwal Posterior capsular rupture can result in various complications, including corneal damage. (entokey.com)
  • Descemet membrane detachment ( DMD ) is a disease of the posterior cornea that mostly occurs as a complication of intraocular surgery but also due to ocular trauma and even spontaneously. (eyewiki.org)
Endothelium7
  • Detection of Lassa virus (LASV) antigen in the anterior uvea and endothelium within the eye of guinea pigs infected with LASV-Josiah and in the epithelium of structures adjacent to the eye in study of LASV targeting of anterior uvea and endothelium of cornea and conjunctiva in eye. (cdc.gov)
  • B) Immunohistochemical (IHC) staining in the endothelium and adjacent stroma of the corneal margin (asterisk) and in the endothelium deep to Descemet's membrane (arrowhead). (cdc.gov)
  • In the peripheral posterior stroma, there were dust-like, bright, granular deposits that tended to increase in number and density toward Descemet's membrane, masking the peripheral endothelium. (scielo.br)
  • This is a partial-thickness cornea transplant that replaces the endothelium and Descemet's membrane just above it. (adveye2020.com)
  • First, the endothelium and Descemet's membrane are carefully stripped away through a small incision and then a circular disc is removed from the inner lining of a donor cornea. (adveye2020.com)
  • The corneal epithelium and endothelium as well as Descemet membrane are spared. (rareguru.com)
  • PPCD, also known as Schlichting dystrophy, is an autosomal dominant disorder of the corneal endothelium and Descemet's membrane. (mdwiki.org)
Stroma10
  • The Descemet membrane is the specialized basement membrane of the endothelial cells positioned between the stroma and the endothelial cell layer. (medscape.com)
  • During this procedure, cannulation or viscodilation of Schlemm's canal can cause a perforation from the canal of Schlemm through Schwalbe's line and create a space between Descemet's membrane and the corneal stroma. (aao.org)
  • Preoperative AS-OCT imaging of recipient stroma can also predict Descemet membrane perforation during big bubble induction. (intechopen.com)
  • Irregular, grey-white, geographic-like opacities are located in the Bowman layer and anterior stroma. (uiowa.edu)
  • It is characterized by lattice lines which are linear, radially oriented, branching refractile opacities described as 'glass like' located in the anterior stroma (See Figure 2A and 2B). (uiowa.edu)
  • OCT imaging may show the opacity as an "inverse dome" that extends from the anterior to posterior stroma with homogenous reflectivity. (aao.org)
  • Compared with the control corneas, there were fewer keratocytes in the anterior stroma (17.380 vs. 22.380/mm 3 ). (scielo.br)
  • Bowman's membrane, a specialized layer of the corneal stroma, underlies the epithelium. (digitalhistology.org)
  • The corneal stroma and Descemet membrane contain sheet-like opacities with clear intervening areas. (arizona.edu)
  • Typically, a ring-shaped yellow-white opacity composed of innumerable fine needle-shaped crystals forms in Bowman layer and the adjacent anterior stroma of the central cornea. (rareguru.com)
Host Descemet membrane2
Optical coherence4
  • Anterior segment optical coherence tomography (AS-OCT) is a valuable tool in corneal transplantation surgery. (intechopen.com)
  • Early changes in clear cornea incision after phacoemulsification: an anterior segment optical coherence tomography study. (jamanetwork.com)
  • However, if there is significant corneal edema, imaging tools such as anterior segment optical coherence tomography (AS-OCT) are fundamental for the diagnosis. (eyewiki.org)
  • The most used and accurate exam for the diagnosis of DMDs is the anterior segment optical coherence tomography (AS-OCT). AS-OCT is a quick, non-contact modality that can determine the exact location, configuration, and extent of the DMD, not only confirming the diagnosis but also guiding the treatment method and outcomes. (eyewiki.org)
Keratoconus1
Graft1
  • Following removal the graft is placed in the anterior chamber and an air bubble infusion facilitates graft-host apposition. (ama-assn.org)
Epithelial3
  • [ 2 ] or membrane, the second layer moving in toward the eye, serves as the smooth adhesion layer for the basement membrane of the epithelial cells. (medscape.com)
  • TEM revealed full thickness corneal perforation with an epithelial plug extending to the lower third of the cornea, but without evidence of epithelial cell migration into the anterior chamber. (biomedcentral.com)
  • Comparison of Persistent Epithelial Defect Treatment With Sutureless Cryopreserved and Dehydrated Amniotic Membrane. (ucsd.edu)
Folds8
  • Diffuse illumination showing Descemet membrane folds after surgery. (medscape.com)
  • Any condition that causes inflammation of the cornea or the anterior chamber can cause Descemet membrane folds. (medscape.com)
  • Descemet membrane folds is common because it is associated with many inflammatory conditions of the eye. (medscape.com)
  • Descemet membrane folds affects women and men equally. (medscape.com)
  • Descemet membrane folds affects all age groups with slower resolution of the folds in elderly persons. (medscape.com)
  • Denion E, Dalens PH, Huguet P, Petitbon J, Gerard M. Radial Descemet's membrane folds as a sign of pterygium traction. (medscape.com)
  • Fleischer rings are usually not present, but prominent folds and areas of thickening in Descemet membrane are common. (aao.org)
  • The study comprised 35 eyes out of which 28 eyes had clear cornea , 4 eyes had descemet membrane folds, 3 eyes with focal stromal oedema and 1 eye with diffuse corneal oedema at post-op day 1. (ascrs.org)
Called Descemet's membrane1
  • The final layer, which is the inner elastic layer of the cornea that separates it from the fluid of the anterior chamber of the eye is called Descemet's membrane. (eyehelp.co.uk)
Bowman's4
  • It is between Bowman's layer anteriorly, and Descemet's membrane posteriorly. (wikipedia.org)
  • Histopathology reveals anterior stromal and subepithelial deposits of hyaline-like material which disrupt and often replace Bowman's layer (See Figure 1A and 1B). (uiowa.edu)
  • Both in Bowman's mem�brane and Descemet's membrane rents are formed which get filled with un�usual type of connective tissue con�taining elastic fibres. (ijo.in)
  • Ruptures in both the Descemet's and Bowman's membranes were observed, more extensive in the left eye. (ijo.in)
Spontaneous1
  • Spontaneous rupture of the Descemet membrane and corneal hydrops can occur, but iron lines, stress lines, and anterior scarring are not typically seen. (aao.org)
Bowman2
  • He also observed that injury to the Descemet membrane was greater than that induced by injury on the Bowman layer, suggesting that surgery on the posterior cornea would be more effective than surgery on the anterior cornea. (medscape.com)
  • Porción anterior y transparente de la cubierta fibrosa del ojo constituida por cinco capas: epitelio escamoso estratificado (epitelio anterior), la LÁMINA LIMITANTE ANTERIOR (membrana de Bowman), el estroma (sustancia propia, tela conectiva), LÁMINA LIMITANTE POSTERIOR (membrana de Descemet) y el endotelio mesenquimatoso (mesotelio). (bvsalud.org)
Endothelial cells2
Rupture1
  • At times acute ectasia develops due to rupture of Descemet's membrane leading to imbibition of aqueous with swelling and opacifica�tion of the cornea. (ijo.in)
Posterior surface1
  • 2) corneal perforation during laser-assisted blepharoplasty, which may be supported by the presence of pigmented cells on the posterior surface of Descemet´s membrane, pointing to a possible iris injury. (biomedcentral.com)
Surgery1
  • Dr. Santiago is a fellowship trained cornea, complex anterior segment, ocular surface and refractive surgery specialist. (rochester.edu)
Membrana1
  • No estroma posterior periférico, havia presença de depósitos granulares brilhantes e com aparência de pó que tendiam a aumentar em número e densidade no sentido da membrana de Descemet, mascarando o endotélio periférico. (scielo.br)
Mesenchymal1
  • Because human mesenchymal stem cells are known to be sensitive to their mechanical environments, we investigated the mechanotransductive potential of Descemet membrane-like microtopography (DLT) to differentiate human mesenchymal stem cells into CEC-like cells. (lww.com)
Third of the cornea2
  • On the other hand, it has also been suggested that the BL may be the strongest biomechanical element of the human cornea followed by the anterior third of the cornea [ 18 ]. (biomedcentral.com)
  • The crystals usually remain in the anterior third of the cornea. (rareguru.com)
Glaucoma1
  • I would look for anterior segment inflammation and uveitis-glaucoma-hyphema syndrome. (crstoday.com)
Donor1
  • Intraoperative AS-OCT assures reaching the proper depth in order, and postoperatively, a surgeon can objectively assess the Descemet membrane and donor association and define complications such as a double anterior chamber. (intechopen.com)
Artificial2
  • Artificial reproduction of Descemet membrane with respect to topography and similar stiffness offers a potential innovative way to bioengineer a functional CEC monolayer from autologous stem cells. (lww.com)
  • The Posner 4-mirror gonioprism is not preferred for evaluating suspected angle recession because of the potential for indenting the central cornea, inducing artificial deepening, and/or distorting of the anterior-chamber angle. (medscape.com)
Iris2
  • Anterior chamber was non-existent and a part of iris was seen through the ulcer. (ijo.in)
  • The iris abnormalities consisting of iridocorneal adhesions to Schwalbe's line and pupillary abnormalities suggest that PACD is a congenital disorder, perhaps a form of anterior chamber dysgenesis. (arizona.edu)
Double anterior chamber1
  • Extensive and central DMDs may create a typical "double anterior chamber" appearance. (eyewiki.org)
Ciliary2
  • In their classic report in 1962, Wolf and Zimmerman described a characteristic tear extending into the anterior ciliary body, separating the longitudinal and circular fibers. (medscape.com)
  • Similarly, unlike infectious or inflammatory processes which exhibit characteristic features, CTK rarely presents with anterior chamber reaction, conjunctival hyperemia, or ciliary flush [7] . (aao.org)
Ocular2
  • 10.1055/b-0035-121722 7 Anterior-Segment Exploration with Optical Coherence TomographyGeorges Baikoff Until recently, most efforts in ocular imaging concerned posterior-segment exploration. (entokey.com)
  • Ocular form of mucous membrane pemphigoid may cause corneal opacity and loss of vision. (mdwiki.org)
Peripheral1
  • A) Anterior uvea with LASV antigen immunolabeled (red) within the peripheral CO and CJ vessels, the FA, CB, and I. Original magnification ×4. (cdc.gov)
Deep2
  • The corneas have a globular shape with a deep anterior chamber. (aao.org)
  • The anterior chambers were deep and the pupils reacted sluggishly to light. (ijo.in)
Aqueous2
  • They are arranged with their apical portion toward the aqueous humor in the anterior chamber. (medscape.com)
  • DMD normally occurs as aqueous enters the pre-descemetic space along a tear in Descemet's membrane (DM). (eyewiki.org)
Photographing the anterior chamber1
  • Use of the Koeppe lens for examining and photographing the anterior chamber angle is also advocated. (medscape.com)
Tear1
  • A tear in Descemet's membrane can be caused by manipulating tools through the wound or a sharp piece of dense nucleus. (reviewofophthalmology.com)
Chamber angle1
  • 26%), optic nerve hypoplasia, variable degrees of corneal clouding with or without a vascularized pannus, and dysgenesis of the anterior chamber angle are frequently present. (arizona.edu)
Surgical1
  • Esteban Santiago, MD, provides expert medical and surgical care to infants, children, adolescents and adult patients suffering from anterior segment eye conditions. (rochester.edu)
Injection1
  • Descemet membrane reattachment, almost immediately after air injection on the anterior chamber. (atlasrleye.com)