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PondiminSerotoninDexfenfluramineCocaineWithdrawnPharmacologicPhendimetrazinePhentermineCombinationCathinoneDrugsProperties

Pondimin1

• As a result of these reports, the manufacturer has voluntarily withdrawn two medications, fenfluramine (Pondimin) and dexfenfluramine (Redux) from the market. (the-medical-dictionary.com)

Serotonin1

• Both medications belonged to a group of appetite suppressants known as serotonergic anorectics, which work by reducing serotonin levels in the brain. (mind-set-travel.com)

Dexfenfluramine1

• When the FDA approved dexfenfluramine in 1996 as a stronger variation of the previously authorised weight-loss medication fenfluramine, this came to an end. (mind-set-travel.com)

Cocaine3

• Caffeine, cocaine, amphetamines, nicotine, and the therapeutic use of stimulants for treatment-resistant depression and attention deficit (hyperactivity) disorder are not discussed in this article. (medscape.com)
• See Cocaine-Related Psychiatric Disorders, Amphetamine-Related Psychiatric Disorders, Caffeine-Related Psychiatric Disorders, Nicotine Addiction, and ADHD for further information on these topics. (medscape.com)
• 4 In the ARC, there are two distinct neuronal populations: one group of neurons produces the orexigenic neuropeptides neuropeptide Y (NPY) and agouti-related peptide (AgRP), whereas the other subset of neurons expresses the anorexigenic neuropeptides proopiomelanocortin (POMC), and cocaine- and amphetamine-regulated transcript. (nature.com)

Withdrawn1

• fenfluramine was subsequently withdrawn from the US market in fall of 1997. (empowerpharmacy.com)

Pharmacologic1

• The pharmacologic effects of phentermine are similar to amphetamines. (empowerpharmacy.com)

Phendimetrazine2

• Phendimetrazine is chemically related to amphetamines and is a Schedule IV drug under the Convention on Psychotropic Substances. (the-medical-dictionary.com)
• To a certain extent phendimetrazine is metabolized into phenmetrazine, which may account for parts of its anorectic effect. (the-medical-dictionary.com)

Phentermine7

• Phentermine is similar to an amphetamine. (avanticoaching.nl)
• The drug combination fenfluramine/phentermine, usually called fen-phen, was an anti-obesity treatment in the early 1990s that utilized two anorectics. (avanticoaching.nl)
• In the past, doctors had combined phentermine and fenfluramine to create the infamous "fen-phen" combination. (mind-set-travel.com)
• In the mid-90s, there was renewed interest in phentermine in combination with another anorectic, fenfluramine, for the treatment of obesity and substance abuse, however, little scientific data support this practice. (empowerpharmacy.com)
• Use of phentermine with other anorectic agents for obesity has not been evaluated and is not recommended. (empowerpharmacy.com)
• Similar to the amphetamines, phentermine increases the release of norepinephrine and dopamine from nerve terminals and inhibits their reuptake. (empowerpharmacy.com)
• A combination of the amphetamine analogs fen- denal switch, vertical sleeve gastrectomy, and adjustable gastric fluramine and phentermine, Fen-Phen's effectiveness helped banding. (eddoctor24h.com)

Combination1

• Perhaps the most infamous is the combination drug Roux-en-Y gastric bypass, biliopancreatic diversion with duo- Fen-Phen. (eddoctor24h.com)

Cathinone1

• Temporal parameters of cathinone, amphetamine and cocaine. (omeka.net)

Drugs1

• Anorectic drugs should be reserved for those who are clinically at risk from being overweight, and then only as part of a comprehensive weight-reducing programme including regular dietary counselling. (nih.gov)

Properties2

• Of the former group, amphetamine and phenmetrazine are no longer recommended because of their stimulant properties and addictive potential. (nih.gov)
• Rats were trained to discriminate between the stimulus properties of intraperitoneally administered d-amphetamine (0.8 mg/kg) and its vehicle in a two-lever, food-motivated operant task. (omeka.net)