• Although the blood generally carries only a small fraction of the total lead body burden, it serves as the initial receptacle of absorbed lead and distributes lead throughout the body, making it available to other tissues or for excretion. (medscape.com)
  • The absorption, distribution and excretion of test substance was determined by performing in vivo study in rats. (europa.eu)
  • For the study of the excretion of 14C-labelled compounds, similarly treated animals were kept in metabolism cages permitting the separate collection of urine and faeces, which were removed at 4 h intervals for a period of 3 days and kept refrigerated until examined. (europa.eu)
  • Pharmacokinetics is the study of the time course for the Of course the actual nature of the relationship between tis- absorption, distribution, metabolism, and excretion of a sue exposure and response, particularly across species, may chemical substance in a biological system. (cdc.gov)
  • Tissue samples weighing 100-200 mg were cut in duplicate from the liver, kidneys, spleen, heart, lungs and hind leg (gastrocnemius muscle) for radioassay. (europa.eu)
  • In addition, gold nanoshells did not induce any tissue damage, such as necrosis, inflammatory infiltrate or fibrosis in mouse liver, spleen, kidney or bone marrow after 6 months. (springer.com)
  • Germinal centers where B cells proliferate and differentiate are poorly developed in all lymphoid tissue, including the spleen. (medscape.com)
  • Ancillary tests included aerobic bacterial culture of liver, spleen, and lung tissue and real-time PCR for Salmonella species in intestinal contents, for avian influenza virus and avian paramyxovirus-1 on an oropharyngeal swab sample, and for West Nile virus in kidney tissue. (cdc.gov)
  • Acute necrotizing foci stippled with karyorrhexis and fibrin exudates and small plasmacytic infiltrates were found in myocardium, peripheral nerves and perineural tissues, liver, spleen, and lungs. (cdc.gov)
  • Fig. 1b, c ) or the pancreas and the white adipose tissue (WAT) that are infiltrated with MAC1-possitve macrophages expressing YFP (Fig. 1d ). (nature.com)
  • This study revealed in general that the level of pesticides in samples of adipose tissue was higher than that in samples of milk from any source (city or rural). (scialert.net)
  • Indeed, while the average of 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane (DDT), predominant specie and its isomers in adipose tissue was 10.02 mg kg -1 in countryside and 6.93 mg kg -1 in the city, it was respectively 0.013 and 0.019 mg kg -1 in milk. (scialert.net)
  • Adipose tissue samples revealed the presence of polychlorinated biphenyl (PCB), Hexachlorobiphenyl (HCB) in addition to pesticides which are found in the milk Average concentrations of organochlorine pesticides in milk matrix were above the Maximum Residue Limits (MRL) of WHO. (scialert.net)
  • Regarding adipose tissue, this trend was also observed, except for DDT and its metabolites whose values were far below the MRL. (scialert.net)
  • Vitamin D accumulates in adipose tissue (AT), and vitamin D deficiency is frequent in obesity. (medscape.com)
  • The high prevalence of vitamin D deficiency in obese subjects [ 3 ] suggests that adipose tissue (AT) has a major role in the body distribution of vitamin D, but the causal relationship between obesity and low levels of circulating 25(OH)D has not been completely elucidated yet. (medscape.com)
  • Animal studies indicate that the liver, lungs, and kidneys have the greatest soft-tissue lead concentrations immediately after acute exposure. (medscape.com)
  • When the animals were preserved either 24 or 72 h post mortem second group, an increase of MDMA and MDA levels in the liver and the eye globe walls was noticed. (erowid.org)
  • The disease can become fatal if extensive amyloid is deposited into the tissue of critical organs, such as the kidneys, liver, or heart. (merckvetmanual.com)
  • or each of these agents, carcinogenicity in rats and/or mice, els, differences in exposure con- there was sufficient evidence of car- for example for the liver (aflatoxins, ditions between studies in animals cinogenicity from studies in rats and/ trichloroethylene [TCE], and vinyl and in humans, or limitations in Part 1 · Chapter 1. (who.int)
  • The blood distributes lead to various organs and tissues. (medscape.com)
  • The distribution of the 14C-labelled test substance was studied using collected samples of blood, organs and tissues by radioassay. (europa.eu)
  • Analysis of the uptake and distribution of radioactivity in the TDI exposed fluids and tissues indicated that some form of the labeled compound, whether TDI, a conjugate, metabolite or hydrolysis product, entered and penetrated throughout the entire system. (cdc.gov)
  • At 20 min and 1 hr after the oral dosing, there was still considerable radioactivity within the contents of the stomach although significant amounts had already been absorbed and distributed throughout the animals. (europa.eu)
  • At 3 and 9 hr, the amount of radioactivity in most tissues of the mother was rapidly decreasing. (europa.eu)
  • No radioactivity was retained in any other fetal tissue. (europa.eu)
  • In animals, based on total radioactivity, cabergoline (and/or its metabolites) has shown extensive tissue distribution. (drugs.com)
  • Preclinical pharmacokinetics were determined in tumor-bearing animals with biodistribution experiments and small-animal PET. (snmjournals.org)
  • Implicit in any of interest in blood (and perhaps other tissues) are col- application of pharmacokinetics to toxicology or risk lected. (cdc.gov)
  • This guidance provides establishments that manufacture animal cells, tissues, and cell- and tissue-based products meeting the definition of a new animal drug (ACTPs) with recommendations for meeting current good manufacturing practice (CGMP) requirements. (fda.gov)
  • Electron microscopy identified nanoshells within blood vessels at 5 and 30 min, within endothelial cells at 3 and 6 h and within cytoplasms of macrophages in the tumoral tissue after 24 h. (springer.com)
  • In conclusion, no toxicity was observed in mice 6 months after administration of PEGylated gold nanoshells and the distribution kinetics progressed from intravascular flow at 30 min to intratumoral cells 24 h later. (springer.com)
  • During more recent years, his reseach has been conducted in the field of regenerative medicine, focussed on antigen expression and immune recognition of human embryonic stem cells and bioartificial heart valves, the latter tissues being of animal origin. (gu.se)
  • Knock-out of the MT gene also renders animals/cells more vulnerable to oxidative stress and DNA alkylating agent-induced toxicity. (go.jp)
  • Systems toxicology, therefore, aims at understanding and exploring the way that different biological components are orchestrated as an ensemble in cells, tissues, and organisms. (brill.com)
  • The transplantation of organs, cells and tissues has become the treatment of choice for a wide range of both fatal and non-fatal diseases, resulting in high levels of demand for transplantation services, particularly in high- and middle-income countries. (who.int)
  • To determine their possible roles in tissues and satellite cells in vitro, their expression pattern was examined in tissues from 40-day-old chickens and in satellite cells from the breast muscles of 1-week-old and 2-week-old chickens using RT-PCR and immunocytochemistry analyses. (scielo.br)
  • However, since there are many different non-muscle cell populations that reside within the tissue, these experiments cannot easily distinguish true myonuclei from those of neighboring mononuclear cells. (frontiersin.org)
  • In the absence of mature B cells, patients lack lymphoid tissue and fail to develop plasma cells, the cells that manufacture antibodies. (medscape.com)
  • Immediate post mortem examination showed œdema and congestion of the lungs in all animals. (unodc.org)
  • The lungs and the lamina propria of the gut lack the normal pattern of lymphocyte distribution. (medscape.com)
  • In the third group, ligation of the large vessels around the heart took place immediately post mortem, but significant differences in blood and tissue MDMA concentrations between rabbits of group 2 and 3 could not be demonstrated. (erowid.org)
  • We found dramatic changes in trace element tissue concentrations between the high p CO 2 /high trace element and control sites, with strong accumulation of iron, lead, copper and cobalt, but decreased concentrations of cadmium, zinc and arsenic proximate to the vent. (peerj.com)
  • C. burnetii persists in stool, urine, milk, and tissues (especially the placenta), so that fomites and infective aerosols form easily. (msdmanuals.com)
  • We further used these WGBS data to detect 50,023 experimentally supported CGIs across bovine tissues and found that they might function as a guard against C-to-T mutations for TSS-HMRs. (umd.edu)
  • In a preclinical model of mouse xenografted with human renal cancer, we analysed the bio-distribution of a single dose (160 μg/kg) intravenously injected of poly-ethylene glycol (PEG)ylated gold nanoshells (~150 nm), in blood, normal and tumoral tissues. (springer.com)
  • This request was initially approved but later rejected because preclinical evidence in animals showed that laetrile was not likely to be effective as an anticancer agent,[ 3 , 11 , 12 ] and because there were questions about how the proposed study was to be conducted. (cancer.gov)
  • Jessica Pamment, professional lecturer at DePaul University, explains how plants are able to photosynthesize and how animals consume other organisms for energy. (coursehero.com)
  • Animals are multicellular eukaryotes that consume other organisms for energy. (coursehero.com)
  • Animals are heterotrophic eukaryotes that must obtain carbon and energy from consuming other organisms. (coursehero.com)
  • They are unable to photosynthesize, but there are a few examples of animals that form a symbiotic relationship with photosynthetic organisms. (coursehero.com)
  • The concentration in the fetuses was greater than that in maternal tissues but it decreases with time. (europa.eu)
  • decreases were seen in tissues and mucosal secretions, critically decreasing potential for virus transmission. (cdc.gov)
  • In the single non-pregnant female, the sites of localization were identical in the adult tissues: brain, nasal epithelium, bone, and renal and hepatic elimination are seen. (europa.eu)
  • The kinetics of distribution and elimination appeared to be the same in female and pregnant animals. (europa.eu)
  • In this study, the plasma concentration profiles of 10 marketed compounds exhibiting two-phase elimination after intravenous administration in humans were evaluated in terms of distribution volumes just after intravenous administration ( V 1 ), at steady state ( V ss ), and in the elimination phase ( V β ) using physiologically based pharmacokinetic (PBPK) modeling implemented in a commercially available simulator (Simcyp). (aspetjournals.org)
  • This study demonstrated that human PBPK models developed with consideration of animal PBPK models could accurately predict distribution volumes in various elimination phases. (aspetjournals.org)
  • The laboratory is especially interested in transport proteins and their impact on tissue drug distribution and elimination. (uwo.ca)
  • Subunit alpha1-, beta1-, beta2-, beta3- and gamma2-immunoreactivities were found throughout the brain, although differences in their distribution were observed. (nih.gov)
  • We observed large differences across cattle tissues in the methylation patterns of global CpG sites, partially methylated domains (PMDs), hypomethylated regions (HMRs), CG islands (CGIs), and common repeats. (umd.edu)
  • It is transmitted to humans on ological surveillance unit and showed etiology, we conducted the following consuming infected animal products no sex differences in occurrence, and study. (who.int)
  • Moreover, absent pharmacodynamic differences identifiable physiological entities but rather are abstract between animal species, it is expected that similar responses concepts with meaning only in terms of a particular calcu- will be produced at equivalent tissue exposures regardless lation. (cdc.gov)
  • Only kidney and nasal epithelium show specific tissue affinities at these early time intervals. (europa.eu)
  • For ethylene oxide, there ylene oxide), nasal tissue (formal- chemicals and chemicals that are was limited evidence of carcinogen- dehyde), and the kidney (TCE). (who.int)
  • Other in direct contact with tissues and fluids studies by Lebanese researchers have Methods of infected animals. (who.int)
  • In this study, a highly heterogeneous distribution of 13 different GABA(A) receptor subunit-immunoreactivities was observed. (nih.gov)
  • This distribution and the apparently typical patterns of co-distribution of these GABA(A) receptor subunits support the assumption of multiple, differently assembled GABA(A) receptor subtypes and their heterogeneous distribution within the adult rat brain. (nih.gov)
  • This, in turn, establishes chronic inflammation and tissue pathology in mice with important ramifications for DNA repair-deficient, progeroid syndromes and aging. (nature.com)
  • Using mice with an engineered ERCC1-XPF defect in tissue-infiltrating macrophages, we provide evidence for a fundamental mechanism by which irreparable DNA damage triggers an exosome-based, metabolic reprogramming that leads to chronic inflammation and tissue pathology in NER progeroid syndromes and likely also during aging. (nature.com)
  • The distribution of 14C-test substance was studied in female and 14.5-day-pregnant mice by whole-body autoradiography after administrating 6.5-6.7 mg test substance/kg bw (11-14 uCi/mouse) by oral intubation. (europa.eu)
  • According to Loewe, the LD 50 (lethality in 50% of animals administered the toxic) of cannabis extracts administered to mice, orally, subcutaneously, and intravenously were 21.6, 11.0, and 0.18 gm/kg respectively. (unodc.org)
  • Animal models of human BTK mutations are confined to mice at this time. (medscape.com)
  • However the process of tissue harvesting from large species is necessarily more complicated than from mice, including the longer delay between euthanasia and tissue collection, and a larger size of lymph nodes. (jove.com)
  • The levels of organochlorine residues in 40 samples of milk and 20 human adipose tissues from two locations in the northern of Côte d Ivoire were determined. (scialert.net)
  • They are characterized by their bioaccumulation properties in the fatty parts of biological beings, such as blood, breast milk and fatty tissues via the food chain ( Smith and Gangolli, 2002 ). (scialert.net)
  • Human breast milk samples (40 samples) and adipose tissues (20 samples) were collected from mothers (17 to 56 years old, average age 30) living in two different locations in the north of Côte d Ivoire (Korhogo and Sinématiali) from 2004 to 2007. (scialert.net)
  • Ensuring animal vaccination, educating people on correct ways of milk pasteurization and handling meat products, and elevating food safety monitoring threshold are key elements in controlling brucellosis. (who.int)
  • We analyse two comprehensive transcriptome datasets from human tissues and human-derived cell lines in terms of the expression profiles of the SLC and ABC families of membrane transporters. (biorxiv.org)
  • Rather than examining whole anemone tissue, we analyzed two different body compartments-the pedal disc and the tentacles, and also examined the distribution of trace elements in the tentacles between the animal and the symbiotic algae. (peerj.com)
  • Based on the behavior of the data, a mathematical assessment is the assumption that the toxic effects in a par- model is selected which possesses a sufficient number of ticular tissue can be related in some way to the concentra- compartments (and therefore parameters) to describe the tion time course of an active form of the substance in that data. (cdc.gov)
  • The compartments do not generally correspond to tissue. (cdc.gov)
  • Altogether there are four main datasets, namely 409 "SLCs" in 59 tissue types and 56 cell lines, and 48 ABCs in the same tissue types and cell lines. (biorxiv.org)
  • Using Holstein cattle, we generated 29 whole genome bisulfite sequencing (WGBS) datasets for 16 tissues, 47 corresponding RNA-seq datasets, and 2 whole genome sequencing datasets. (umd.edu)
  • Some animal studies indicate chemical. (cdc.gov)
  • The SULF1 and SULF2 transcripts were widely distributed in various tissues. (scielo.br)
  • The role of MT in Cd toxicology has become clearer by the use of MT-I transgenic and MT-I and -II knock-out animals. (go.jp)
  • His research focus is the analysis of the molecular foundation of signal transmission in the various structural and functional organizational units of the human brain, and in the brains of transgenic animals, that serve as models of mental and neurological diseases. (rwth-aachen.de)
  • This group of re-emerging human and animal diseases has recently attracted much attention, as well as concern, both in the scientific world and among the general public. (who.int)
  • The epidemiology, both in human beings and animals, has been reviewed and the causative agents described. (who.int)
  • Diagnosis, pathology, prevention and control are addressed, showing how the risk to animals and human beings could be minimized. (who.int)
  • Large-sized gold nanoparticles, promising imaging and therapeutic tools in human cancer, need long-term studies evaluating tissue bio-distribution in blood, organs and tumor. (springer.com)
  • We performed a sequential analysis of uptake and distribution of large-sized PEGylated gold nanoshells and focussed the study on their intracellular distribution in the xenografted human cancers, as well as on their long-term tolerance in normal mouse organs. (springer.com)
  • When developing human PBPK models, the insight gained from prior animal PBPK models based on nonclinical data informed the optimization of the lipophilicity input of the compounds and the selection of the appropriate mechanistic tissue partition methods. (aspetjournals.org)
  • The accuracy of V 1 , V ss , and V β values predicted that using human PBPK models developed in accordance with prior animal PBPK models was superior to using those predicted using conventional approaches, such as allometric scaling, especially for V 1 and V β . (aspetjournals.org)
  • The distribution volumes predicted using human PBPK models based on prior animal PBPK modeling were more accurate than those predicted without reference to animal models. (aspetjournals.org)
  • The most commonly used approaches predict human distribution volumes of drugs from animal data via interspecies scaling techniques, such as allometric scaling. (aspetjournals.org)
  • Laetrile has shown little anticancer activity in animal studies and no anticancer activity in human clinical trials. (cancer.gov)
  • The symptoms reported are consistent with botulism, and while further testing is underway to pinpoint the cause of the horse illnesses, horse owners and handlers should take precautions to protect human and animal health. (oregonvma.org)
  • The lack of documentation makes it difficult to 1 Animal-to-human, or xenogeneic, transplantation. (who.int)
  • Katrin Amunts for many years on a three dimensional model of the human brain that is based on thousands of microscopic tissue sections. (rwth-aachen.de)
  • C. burnetii is also maintained in nature through an animal-tick cycle, but arthropods are not involved in human infection. (msdmanuals.com)
  • In the absence of quantitative data in the human, this process is often dependent upon the use of animal and in vitro data to estimate human response. (cdc.gov)
  • In recent years, newly recognized sequelae identified in human cases has highlighted the importance of continued investigations of non-lethal infection both in humans and animal models. (cdc.gov)
  • Guinea pigs are important animal models for human disease, and both outbred and inbred lines are utilized in biomedical research. (cdc.gov)
  • Samples from large animals, including both livestock and wildlife species, are of interest in the study of zoonotic diseases. (jove.com)
  • A range of lymph nodes can be collected from animals infected with different diseases. (jove.com)
  • A variety of biochemical, molecular biological and genetic methods are employed in cellular and animal models together with studies in humans. (uwo.ca)
  • Transplant Rejection, in medicine, is the immune reaction of a host organism to a foreign biological tissue. (searchquotes.com)
  • Post-mortem redistribution is known to influence blood and tissue levels of various drugs. (erowid.org)
  • No studies were located regarding systemic effects in animals after inhalation exposure to tetryl. (cdc.gov)
  • Sociodemographic data, exposure to animals and animal products, knowledge about brucellosis, symptoms and history of past brucellosis infections were collected. (who.int)
  • Animals were monitored for neurological deficits and were killed 3 days after infusion. (thejns.org)
  • This chapter presents a summarized account of their habitats, distribution, behavior, morphology, and taphonomic signatures on bone and soft tissue. (improbable.com)
  • However, biopsy of lymphoid tissue and bone marrow examination are not currently performed in the workup of most cases of XLA. (medscape.com)
  • AL amyloid is another common form of amyloid protein that usually forms in animals with certain types of cancer (plasma cell tumors or myelomas). (merckvetmanual.com)
  • Here, we report on the clinical impact of a novel NiV-derived nonspreading replicon particle lacking the fusion (F) protein gene (NiVF) as a vaccine in three small animal models of disease. (cdc.gov)
  • The uptake and distribution of carbon-14 (C-14) labeled toluene- diisocyanate (584849) (TDI) was studied in guinea-pigs. (cdc.gov)
  • Using inductively coupled plasma mass spectrometry (ICP-MS), dark field and electron microscopy, we performed a sequential study of nanoshell uptake and distribution in the tumor. (springer.com)
  • Fourteen days after the final administration, [3H]-paroxetine binding to 5HT uptake sites was reduced by 89% in membranes prepared from tissue samples of frontal cortex. (erowid.org)
  • Distribution maps and photographs of several taxa are included, as are tables that summarize ecological and morphological characteristics of each species such as habitat, dental formula, animal size, conservation status, and typical taphonomic signatures. (improbable.com)
  • Although DNA methylation has been well studied in humans and other model species, its distribution patterns and regulatory impacts in cattle are still largely unknown. (umd.edu)
  • Animal reproduction is mostly sexual, but some species are able to reproduce asexually. (coursehero.com)
  • Here, at the National Animal Disease Center, we study infections of livestock with species like brucella abortus, which causes brucellosis in cattle and bison, and E.Coli O157:H7 as shed from the intestinal tracks of cattle. (jove.com)
  • We will also recover tissue samples from wildlife species, like deer and elk. (jove.com)
  • Studies of tissues in these natural host species are generally more relevant to the natural progression of disease than mouse models. (jove.com)
  • However, more recently evolved animals show radial (cylindrical, like a sea anemone) or bilateral (mirrored on either side of a mid-line, like an alligator) symmetry and are able to navigate their environment. (coursehero.com)
  • Using immunocytochemistry, we investigated the distribution of GABA(A) receptor subunits deriving from 13 different genes (alpha1-alpha6, beta1-beta3, gamma1-gamma3 and delta) in the adult rat brain. (nih.gov)
  • Afterwards, the differing expression - that is the individual distribution profile for brain regions of more than 20 different receptors for signal transfer molecules - is transferred into the functional and structural correlation. (rwth-aachen.de)
  • The brain is a site of distribution as well. (medscape.com)
  • Children retain more lead in soft tissue than adults do. (medscape.com)
  • This protocol provides an overview of procedures for the isolation of RNA for the transcriptomic profiling of lymph node tissues from large animals, including steps in the identification and excision of lymph nodes from livestock and wildlife, sampling approaches to provide consistency across multiple animals, and considerations plus representative results for the post-collection preservation and processing for RNA analysis. (jove.com)
  • In this JoVE video, we will be sharing with you information about the collection and processing of lymph nodes from large animals for use in downstream RNA experiments. (jove.com)
  • Here, we'll present a protocol for the isolation of large animal lymph nodes for RNA study that will be informative for molecular biologists involved in the transcriptomic studies of large animal infections, as well as veterinary researchers commencing transcriptomic studies. (jove.com)
  • We found that like non-adapted wild-type EBOV, guinea pig-adapted EBOV resulted in widespread tissue infection, variably associated with tissue pathology, and alterations in clinical and immunological analytes in the absence of overt disease. (cdc.gov)
  • Furthermore, because of the insolubility of pure cannabinoid compounds in water, their intravenous administration in animals requires the addition of solvents such as tween, alcohol, ethylene glycol, which have to be taken into account. (unodc.org)
  • An animal model was used in an attempt to elucidate this problem for the amphetamine analogue, 3,4-methylenedioxymethamphetamine MDMA. (erowid.org)
  • Rabbits received 1 mg/kg MDMA intravenously iv and were killed 2 h later in order to simulate the state of complete distribution in the body. (erowid.org)
  • Animals were injected with MDMA (20 mg/kg sc) twice daily for 4 days. (erowid.org)
  • 2009. Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study. . (oregonstate.edu)
  • This insolubility makes it very difficult to study Δ 9 -THC in isolated tissue preparations suspended or incubated in the standard electrolyte solutions (such as Krebs Ringer) and obtain dose response curves. (unodc.org)
  • Within the tentacles, the various trace elements displayed different partitioning patterns between animal tissue and algal symbionts. (peerj.com)
  • We detected that each tissue had a distinct set of PMDs, which showed tissue-specific patterns. (umd.edu)
  • Furthermore, pharmacological and toxicological studies are performed on animals with compounds administered intravenously, by mouth or intraperitoneally. (unodc.org)
  • In addition to demonstrating that compounds optimized with Isis' chemistries produce superior results in animal models when compared to unoptimized compounds, the grant funds the discovery of RNAi-based drugs. (news-medical.net)
  • The current classification of animals is primarily based on characteristics of embryonic development and whether or not the animal molts (sheds outer covering to make room for growth). (coursehero.com)
  • It requires only 8 weeks for animal experimental treatment and a further few weeks for quantitative analysis of immunohistochemically-demonstrated glutathione S-transferase placental from positive hepatic foci. (go.jp)
  • Here, we show that persistent DNA damage accumulation in tissue-infiltrating macrophages carrying an ERCC1-XPF DNA repair defect ( Er1 F/− ) triggers Golgi dispersal, dilation of endoplasmic reticulum, autophagy and exosome biogenesis leading to the secretion of extracellular vesicles (EVs) in vivo and ex vivo. (nature.com)
  • We tested a classification of the HMRs based on their distributions relative to transcription start sites (TSSs) and detected tissue-specific TSS-HMRs and genes that showed strong tissue effects. (umd.edu)
  • Such CD133+ TICs have also been isolated from three other HCC animal models and patient HCC tissues and were characterized by their NANOG-dependent self-renewal and tumor-initiating activities 6 , 7 , 8 . (nature.com)
  • In experiments lasting for more than 24 h the animals were provided with food and water ad lib. (europa.eu)
  • In vivo, a higher SUV was reached in tumor-bearing animals, leading to larger areas under the curve as calculated from biodistribution experiments. (snmjournals.org)
  • Testing of the alfalfa cubes and other feed and tissue samples is in progress. (oregonvma.org)
  • The tissue samples are analyzed with the help of modern image evaluation methods. (rwth-aachen.de)
  • such as raw dairy products and raw a seasonal distribution related to the meat of cattle, goat and sheep, or when herds' birthing season [12]. (who.int)
  • Brucellosis is considered a major study highlighted the antimicrobial A matched case-control study was animal-related occupational health resistance of Brucella spp. (who.int)