• receptor
  • The data obtained with the angiotensin receptor subtype-selective compounds, losartan and PD 123319, suggest that the depressor action is an AT 1 -mediated effect and give no indication that AT 2 receptors could be involved. (ahajournals.org)
  • gene
  • Some strains of mice appear to carry a duplication of the renin structural gene (Ren-2) near the Ren-1 locus. (ahajournals.org)
  • Sequence analysis of a 319 bp renin cDNA recombinant isolated from a kidney library from the two-gene strain DBA/2Ha corresponds to a transcript of the Ren-1 gene. (ahajournals.org)
  • activity
  • Our experiments also address the hypothesis that angiotensinogenic depressor responses could be mediated by non-AT 1 /AT 2 receptors, because of the experiments by Haberl 6 described above and the observation that angiotensin IV and angiotensin-(1-7) have dilator or depressor activity. (ahajournals.org)
  • Evidence of enhanced renin-angiotensin system (RAS) activity in PCOS suggests an important correlation between the RAS and PCOS [ 10 , 11 ]. (mdpi.com)