• acute myocardial
  • Virtually all regional acute myocardial infarcts are caused by thrombosis developing on a culprit coronary atherosclerotic plaque. (bmj.com)
  • Given the importance of thrombosis as the trigger for acute myocardial ischaemia, it is necessary to know something about the structure of plaques before thrombotic events occur and why there should be a sudden change from a stable state (no thrombus) to an unstable state (thrombus). (bmj.com)
  • women with microvascular
  • Nebivolol has unique antioxidant properties and dilates blood vessels and it is therefore proposed that treatment with nebivolol will reduce angina (chest symptoms) in women with microvascular disease as well as improve exercise capacity, reduce resource utilization and improve other measures of artery function. (clinicaltrials.gov)
  • In the absence of robust outcomes data to drive the care of these women with microvascular ischemia, various approaches are taken, in addition to the fundamental management of baseline risk factors. (clinicaltrials.gov)
  • Nevertheless, given that these women with microvascular ischemia continue to have higher morbidity and mortality, as well as increased resource consumption, there is a widely recognized need for effective therapeutic agents to reduce symptoms, improve quality of life, decrease resource consumption, and ultimately reduce mortality. (clinicaltrials.gov)
  • morbidity and morta
  • In particular, myocardial ischemia (MI) is a leading cause for cardiovascular morbidity and mortality despite controlling certain risk factors such as arteriosclerosis and treatments via surgical intervention (Thygesen). (jove.com)
  • ischemic
  • Further the degree to which overlap exists between extensive CAD and severe ischemia is also unclear but remains an important goal for future developments in risk stratification, which will also focus on the interplay between nonischemic CAD to ischemic mild to severe CAD. (onlinejacc.org)
  • symptoms
  • It is interesting that blood cultures and DNA amplification of the operative tissue were both negative, suggesting chronicity of this process, which was not recognized until the patient developed symptoms equivalent to those of angina. (ahajournals.org)
  • grafts
  • You elect to perform transmyocardial revascularisation to the circumflex territory, prior to placing the grafts, but you resolve to review the literature to check that you have not unnecessarily increased the risk of mortality for this patient, and that this additional procedure might improve the chances or resolving your patient's angina. (bestbets.org)
  • Free vein grafts are also used frequently during reconstructive surgery in situations where recipient vessels are damaged or are otherwise inadequate and require bridging vein grafts to connect graft and recipient blood vessels or to restore vessel length in situations where recipient vessels have been surgically debrided. (wikipedia.org)
  • This is not surprising given the similar anatomy and physiology between types of vein grafts and given that vascular graft experience similar stresses, including the physical trauma of harvesting and handling, post-harvest ischemia, oxidative stress, reperfusion injury and adaptive stress in the new post grafting environment. (wikipedia.org)
  • stable
  • Chronic stable angina guidelines - is there an emerging international consensus? (bjcardio.co.uk)
  • Stable angina is the most common manifestation of coronary heart disease. (bjcardio.co.uk)
  • Guidelines for the management of stable angina are relatively conservative in their approach, given their process of development. (bjcardio.co.uk)
  • Moreover, stable angina management has not been as rigorously evaluated in large randomised trials as other coronary conditions. (bjcardio.co.uk)
  • Stable angina, assessed according to the Rose Angina Questionnaire, is estimated to affect about 6% of individuals (both men and women) across 31 countries. (bjcardio.co.uk)
  • The Euro-Heart Survey provides insights into how the management of stable angina has evolved. (bjcardio.co.uk)
  • CABG
  • In addition a systematic review recently published by the STS as a guideline for the use of TMR with or without CABG as treatment for refractory angina was included. (bestbets.org)
  • study
  • Efficacy of calcium channel blockers in the treatment of the myocardial bridging: a pilot study. (radiopaedia.org)
  • Cardiopulmonary exercise testing is an ideal diagnostic test in this study as it will provide unique information on how microvascular ischemia influences functional capacity as measured through sensitive gas exchange parameters. (clinicaltrials.gov)
  • Results
  • He studied the effects of acidosis and ischaemia on myocardial function and Ca exchange and his early results suggested that developed force and Ca exchange were more responsive to acidosis within the cell than to extracellular acidosis. (wikipedia.org)
  • quality of l
  • He currently has CCS grade IV angina and has told you that he has no quality of life and is desperate for something to be done. (bestbets.org)