• isoflurane
  • We now report that mutation of these residues within either GABA A α2 (S270 or A291) or β1 (S265 or M286) subunits resulted in receptors that retain normal or near-normal gating by GABA but are insensitive to clinically relevant concentrations of another inhaled anesthetic, isoflurane. (aspetjournals.org)
  • injection
  • citation needed] Following intravenous injection, the drug rapidly reaches the brain and causes unconsciousness within 30-45 seconds. (wikipedia.org)
  • During surgeries in and around the eye, such as corneal transplant surgery, the patient often requires injection of a local anesthetic into the eye. (wikipedia.org)
  • dose
  • It can occur either because of failure to deliver sufficient anesthetic medication to the patient's body, or because of individual patient factors that mean the patient is resistant to what would normally be an adequate dose of anesthetic medication. (wikipedia.org)
  • airway
  • However, most of the halogenated anesthetics are irritating to the airway, perhaps leading to coughing, laryngospasm and overall difficult inductions. (wikipedia.org)
  • Administration
  • As the only adrenal steroidogenesis inhibitor available for intravenous or parenteral administration, it is useful in situations in which rapid control of hypercortisolism is necessary or in which oral administration is unfeasible. (wikipedia.org)
  • In the brain, etoxadrol slows down the synthesis of serotonin to 50-60% of control rates and speeds up the rate of dopamine synthesis by up to 200% of the normal rate 4-6 hours after intravenous administration. (wikipedia.org)
  • Intravenous administration is the most reliable and rapid way to accomplish euthanasia. (wikipedia.org)
  • surgery
  • If you are having surgery, your doctor will give you medicine called an anesthetic. (icdlist.com)
  • The likelihood of a complication occurring is proportional to the relative risk of a variety of factors related to the patient's health, the complexity of the surgery being performed and the type of anesthetic used. (wikipedia.org)
  • Inhalation anesthetics are vaporized and mixed with other gases prior to their inhalation by the patient before or during surgery. (wikipedia.org)
  • onset
  • They have a slower onset and longer half-life than ester anesthetics, and are usually racemic mixtures, with the exception of levobupivacaine (which is S(-) -bupivacaine) and ropivacaine (S(-)-ropivacaine). (wikipedia.org)
  • patient
  • The patient begins to sneeze just as the needle is inserted into the eye, often resulting in the anesthesiologist having to remove the needle before injecting the local anesthetic in order to avoid damaging the patient's eye. (wikipedia.org)