• analgesia
  • Despite the potential for renal impairment when used at anesthetic doses, no significant adverse effects have been reported in the literature when it is used at the lower doses (up to 6 milliliters) used for producing analgesia and sedation. (wikipedia.org)
  • Administration
  • As the only adrenal steroidogenesis inhibitor available for intravenous or parenteral administration, it is useful in situations in which rapid control of hypercortisolism is necessary or in which oral administration is unfeasible. (wikipedia.org)
  • In the brain, etoxadrol slows down the synthesis of serotonin to 50-60% of control rates and speeds up the rate of dopamine synthesis by up to 200% of the normal rate 4-6 hours after intravenous administration. (wikipedia.org)
  • Intravenous administration is the most reliable and rapid way to accomplish euthanasia. (wikipedia.org)
  • PMID 11606122 Rigby-Jones AE, Sneyd JR, Vijn P, Boen P, Cross M. First administration to man of Org 25435, an intravenous anaesthetic: A Phase 1 Clinical Trial. (wikipedia.org)
  • drugs
  • Lipid emulsion therapy has also been used successfully to treat cardiac arrest and intractable arrhythmias caused by overdoses of antiepileptic drugs, cardiovascular drugs, and psychotropic medications, but experience with intravenous lipids as antidotal therapy in these clinical situations is limited. (aacn.org)
  • without this, they can move and the anesthesiologists are alerted and provide more anesthetic drugs to render the patient unconscious again. (wikipedia.org)
  • dose
  • Study Design: Sequential study of an intravenous anaesthetic in young healthy males, at up to eight dose levels. (clinicaltrials.gov)
  • It can occur either because of failure to deliver sufficient anesthetic medication to the patient's body, or because of individual patient factors that mean the patient is resistant to what would normally be an adequate dose of anesthetic medication. (wikipedia.org)
  • ester
  • They have a slower onset and longer half-life than ester anesthetics, and are usually racemic mixtures, with the exception of levobupivacaine (which is S(-) -bupivacaine) and ropivacaine (S(-)-ropivacaine). (wikipedia.org)