EndocannabinoidsPolyunsaturated AlkamidesCannabinoid Receptor ModulatorsArachidonic AcidsAmidohydrolasesHydrolysisReceptor, Cannabinoid, CB1CarbamatesGlyceridesReceptors, CannabinoidCannabinoidsMonoacylglycerol LipasesReceptor, Cannabinoid, CB2PyrazolesPiperidinesCannabinoid Receptor AgonistsCannabinoid Receptor AntagonistsBenzoxazinesDronabinolNaphthalenesReceptors, DrugBenzodioxolesBornanesCyclohexanolsMorpholinesBenzyl CompoundsEthanolaminesTRPV Cation ChannelsRats, Sprague-DawleyPalmitic AcidsCannabidiolSynaptic TransmissionNeural InhibitionBenzamidesCannabisSignal TransductionKineticsLipoprotein LipaseDose-Response Relationship, DrugLong-Term Synaptic DepressionRats, WistarInhibitory Postsynaptic PotentialsBrainSynapsesAdenosine TriphosphatePeriaqueductal GrayNeuronsgamma-Aminobutyric AcidEnzyme InhibitorsPatch-Clamp TechniquesCalcium Channel BlockersPhospholipase DReceptors, Metabotropic GlutamateMice, Inbred C57BLOleic AcidsAnalgesicsPhenylmethylsulfonyl FluorideHippocampusCapsaicinExcitatory Postsynaptic PotentialsNeuronal PlasticityMice, KnockoutSubstrate SpecificityPresynaptic TerminalsMethoxyhydroxyphenylglycolCalciumMass SpectrometryAdenosine TriphosphatasesChromatography, High Pressure LiquidPainElectric StimulationPyramidal CellsGlutamic Acid