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  • synthesis
  • The method is based on the measurement of the incorporation of bromouridine (as the uridine analogue) into the nascent RNA during RNA synthesis inhibition (RSI) induced by the stalling of RNA polymerases at DNA lesions on the transcribed DNA strand, which triggers transcription-coupled nucleotide excision repair (TC-NER). (go.jp)
  • The synthesis of 5-methyl-MDA can be found online. (wikipedia.org)
  • chemical
  • To identify gene expression that can be closely involved in chemical-induced hepatocellular hypertrophy, the hepatic gene expression profile was assessed by cDNA microarray analysis in male F344 rats fed for 3 days, 4 weeks, and 13 weeks a diet containing a hepatocellular hypertrophy inducer, either phenobarbital (500 ppm), clofibrate (2,500 ppm), or piperonyl butoxide (20,000 ppm). (go.jp)
  • When we tested chemical agents (camptothecin, etoposide, 4-nitroquinoline-1-oxide, mitomycin C, methyl methanesulfonate, and cisplatin) in HeLa cells by the method, RSI indicative of genomic toxicity was observed in the nucleoli of the tested cells. (go.jp)
  • 6-MAPDB (1-(2,3-dihydrobenzofuran-6-yl)-N-methylpropan-2-amine) is a chemical compound which might be an entactogenic drug. (wikipedia.org)
  • Serotonin
  • 5-Methyl-MDA acts as a selective serotonin releasing agent (SSRA) with IC50 values of 107nM, 11,600nM, and 1,494nM for serotonin, dopamine, and norepinephrine efflux. (wikipedia.org)
  • Recent research has used data on 2-methyl-MDA and 5-methyl-MDA to help guide computer modeling of the serotonin transporter complex. (wikipedia.org)
  • substance
  • 3a) 'Commission' means the Commission for Mental Health, Developmental Disabilities, and Substance Abuse Services established under Part 4 of Article 3 of Chapter 143B of the General Statutes. (ncleg.net)
  • 4) 'Control' means to add, remove, or change the placement of a drug, substance, or immediate precursor included in Schedules I through VI of this Article. (ncleg.net)
  • 3. The physical appearance of the tablets, capsules or other finished product containing the substance is substantially identical to a specified controlled substance. (ncleg.net)
  • Maximum 3 years imprisonment Schedule IV: It is not an indictable offence to possess a Schedule IV substance for personal use. (wikipedia.org)
  • Lysergic
  • Development of tolerance in man to LSD-25 by prior administration of MLD-41 (1-methyl-d-lysergic acid diethylamide). (springer.com)
  • compounds
  • Derivatives include compounds such as 1-methyl-indane and 2-methyl-indane (where one methyl group is attached to the five carbon ring), 4-methyl-indane and 5-methyl-indane (where one methyl group is attached to the benzene ring), various dimethyl-indanes, and various pharmaceutical derivatives. (wikipedia.org)
  • effects
  • 3] The most common side effects are cardiovascular, such as fast or irregular heartbeat, and psychological, such as anxiety. (pearltrees.com)
  • legally
  • 5-Methyl-MDA is not scheduled at the federal level in the United States, but it is possible that 5-Methyl-MDA could legally be considered an analog of MDA, in which case, sales or possession could potentially be prosecuted under the Federal Analogue Act. (wikipedia.org)
  • safrole
  • Wacker oxidation of safrole to yield 3,4-methylenedioxyphenylpropan-2-one (MDP2P) followed by reductive amination or via reduction of its oxime. (wikipedia.org)
  • Safrole (4-allyl-1,2-methylenedioxybenzene or shikimol) is a phenylpropene. (wikipedia.org)
  • Safrole itself is an acetal which is readily hydrolysed in acidic solutions to give 4-allylpyrocatechol and formaldehyde (or formaldehyde polymers). (wikipedia.org)
  • agent
  • A CB weapon is an integrated device of (1) agent, (2) dissemination means, and (3) delivery system. (wikipedia.org)
  • substances
  • 4] Circa 1993, the DEA added cathinone to the Controlled Substances Act's Schedule I. Dextroamphetamine. (pearltrees.com)
  • acid
  • This is reduced to the 2-aminoindan following a modification of Nichols' earlier method from a paper discussing DOM analogues, using a Pd/C catalyst in glacial acetic acid with catalytic H2SO4. (wikipedia.org)